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( Younjeong Lee ),( Kyung-jin Min ),( Sanghoon Lee ),( Jin Hwa Hong ),( Jae Yun Song ),( Jae-kwan Lee ),( Nak Woo Lee ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: To prove that making distinction between the cytology of Atypical Squamous Cells of Undetermined Significance (ASCUS) and Low-grade squamous intraepithelial lesion (LSIL) or between Atypical Squamous Cells cannot exclude HSIL (ASC-H) and High-grade Squamous Intraepithelial Lesion (HSIL) in clinical practice may not be necessary. Methods: Including the referrals from local hospitals, we investigated women who visited Korea university medical center, Guro hospital for cervical cancer screening from February 2004 to December 2014. Through chart review, we collected data of cervical biopsy of four groups: ASCUS, LSIL, ASC-H, and HSIL. Using Cochran-Mantel-Haenszel statistics method, we compared the pathologic results of cervical biopsy of ASCUS group to LSIL group, and ASC-H group to HSIL group in the same manner. Results: Of 216,723 women enrolled for Papanicolaou (Pap) smears, after excluding the results of cervical biopsy other than WNL, CIN1, CIN2, CIN3/CIS, and cervical cancer, total 855 women were included in this study. There were 161 women with cytology result of ASCUS, 425 women with LSIL, 22 women with ASC-H, and 247 women with HSIL. According to the Cochran-Mantel-Haenszel statistics, the p-value for the comparison between ASCUS group and LSIL group was 0.00068 (p< 0.05), which was statistically significant by proving differentiation between two groups. Conversely, the p-value for the association between ASC-H and HSIL was 0.26834 (p >0.05) which accepted the hypothesis of the study by not distinguishing two groups. Overall, the results of cervical biopsy between ASCUS and LSIL did show differentiation, yet ASC-H and HSIL did not have significant difference. Conclusion: Although the cytology results of ASCUS and LSIL are necessary to be distinguished, making distinction between the cytology of ASC-H and HSIL in the clinical practice may not be necessary. Further studies of comparing cytology of these groups may be helpful to simplify the colposcopy results in the real world.
Validation of Methods Based on PCR for the Detection of GM Events in South Korea
Young Rae Cho,Min Ki Shin,Eun-ju Song,Jun Hyun Sung,Younjeong Han,Min Young Bae,Ji Hyun Yoo,Sunmi Kim,Jyongeun Myung,Jisoo Hong,Sewook Park,Chohee Kim,Dongmi Choi,Mee Kyung Kim 한국식품영양과학회 2019 한국식품영양과학회 학술대회발표집 Vol.2019 No.10