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Matsuura Takumi,Yamamoto Tetsuya,Matsumoto Yoshiyuki,Itino Takao 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.4
We reconstructed Stomaphis phylogeny and analyzed evolutionary host-plant shifts. The molecular phylogeny revealed 23 well-supported lineages, each specialized to use specific host plant family, whilst host plants of Stomaphis aphids ranged across 6 orders, 11 families, 21 genera, and 28 species. This combination of high host specificity with evolutionarily distant host shifts is exceptional in herbivores. To explain this pattern, we propose one hypothesis among several possibilities: Stomaphis aphids are generalists with respect to the defensive chemicals produced by the plant, but specialists with respect to the stem surface structure of the host tree. This hypothesis predicts that tree taxa having stem surface structures preferred by Stomaphis would be used again and again by genetically distinct Stomaphis lineages. Consistent with this prediction, we found that different (occa sionally phylogenetically distant) Stomaphis lineages shared the same host plant genera such as Alnus and Betula. This result suggests that, in the course of their evolutionary history, Japanese Stomaphis aphids have repeatedly colonized a limited number of host plant genera.
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Transient Analysis of Self-Powered Energy-Harvesting using Bond-Graph
Makihara, Kanjuro,Shigeta, Daisuke,Fujita, Yoshiyuki,Yamamoto, Yuta The Society for Aerospace System Engineering 2015 International Journal of Aerospace System Engineer Vol.2 No.1
The transient phenomenon of self-powered energy-harvesting is assessed using a bond-graph method. The bond-graph is an energy-based approach to describing physical-dynamic systems. It shows power flow graphically, which helps us understand the behavior of complicated systems in simple terms. Because energy-harvesting involves conversion of power in mechanical form to the electrical one, the bond-graph is a good tool to analyze this power flow. Although the bond-graph method can be used to calculate the dynamics of combining mechanical and electrical systems simultaneously, it has not been used for harvesting analysis. We demonstrate the usability and versatility of bond-graph for not only steady analysis but also transient analysis of harvesting.
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Toshikazu Moriwaki,Masahiko Gosho,Akinori Sugaya,Takeshi Yamada,Yoshiyuki Yamamoto,Ichinosuke Hyodo 대한암학회 2021 Cancer Research and Treatment Vol.53 No.3
Purpose Maintenance therapy after oxaliplatin withdrawal is useful in patients with metastatic colorectal cancer (mCRC). This study aimed to investigate the timing of discontinuation or reintroduction of oxaliplatin and the optimal maintenance therapy regimen for survival.Materials and Methods PubMed and conference abstracts were searched to select phase II and III trials of first-line oxaliplatin-containing therapy with or without bevacizumab using maintenance therapy for mCRC. Correlations of median overall survival (OS) with induction therapy regimens, induction therapy duration, maintenance therapy regimens (fluoropyrimidine plus bevacizumab [FP+Bev], FP/Bev alone, and no treatment), and oxaliplatin reintroduction were investigated using correlation and weighted multivariate regression analyses.Results Twenty-two treatment arms were analyzed, including 2,581 patients. The maintenance therapy regimen FP+Bev showed the strongest correlation with a prolonged OS (Spearman’s partial correlation coefficient=0.42), and the other three variables correlated weakly with the OS. The maintenance therapy regimen significantly interacted with the induction chemotherapy duration (p=0.019). The predicted OS for FP+Bev crossed the lines of FP/Bev alone at 18 weeks of induction therapy, and of no treatment at 23 weeks. The corresponding OS at 12 and 27 weeks of induction therapies were 28.6 and 24.2 months for FP+Bev, 25.9 and 28.8 months for FP/Bev alone, and 20.5 and 27.5 months for no treatment.Conclusion The optimal maintenance therapy regimen for the OS is a continuous induction therapy as long as possible followed by FP/Bev alone and switching to FP+Bev within approximately 4 months if induction therapy is discontinued.
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Yoko Kato,Kuriko Kagitani-Shimono,Junko Matsuzaki,Ryuzo Hanaie,Tomoka Yamamoto,Koji Tominaga,Yoshiyuki Watanabe,Ikuko Mohri,Masako Taniike 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.3
Objective: The purpose of the present study was to clarify the relationship between white matter tracts and cognitive symptoms in children with high-functioning autism spectrum disorder (ASD). Methods: We examined the cognitive functions of 17 children with high-functioning ASD and 18 typically developing (TD) controls and performed diffusion tensor imaging (DTI) tractography. We compared the results between the groups and investigated the correlations between the cognitive scores and DTI parameters within each group. Results: The Comprehension scores in the ASD group exhibited a positive correlation with mean diffusivity (MD) in the forceps minor (F minor). In the TD group, the Comprehension scores were positively correlated with fractional anisotropy (FA) in the right inferior fronto-occipital fasciculus (IFO) and left anterior thalamic radiation (ATR), and negatively correlated with MD in the left ATR, radial diffusivity (RD) in the right IFO, and RD in the left ATR. Additionally, a positive correlation was observed between the Matching Numbers scores and MD in the left uncinate fasciculus and F minor, and RD in the F minor. Furthermore, the Sentence Questions scores exhibited a positive correlation with RD in the right inferior longitudinal fasciculus. Relative to TD controls, the specific tract showing a strong correlation with the cognitive scores was reduced in the ASD group. Conclusion: Our findings indicate that white matter tracts connecting specific brain areas may exhibit a weaker relationship with cognitive functions in children with ASD, resulting in less efficient cognitive pathways than those observed in TD children.
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