중소·중견기업 지원형태에 따른 지원 효과 분석: 월드클래스300 기업을 대상으로

윤상필(Yoon, Sang-Pil),정양헌(Chung, Yang-hon),한수혁(Han, Su-hyeok),한상준(Han, Sang-Jun) 한국경영교육학회 2021 경영교육연구 Vol.36 No.3

肝固有動脈結紮 및 門脈狹窄이 正常家兎의 干組織에 미치는 影響

尹必逵,孫基燮 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2

This study was undertaken to investigate the effect of proper hepatic artery ligation and portal vein stenosis on the liver tissues of the normal rabbits and the relationship between hepatic artery and portal vein in the intrahepatic circulation. The experimental groups were divided in to 3 groups; proper hepatic artery ligation group, portal vein stenosis group and control group. The livers of each group were observed grossly and microscopically at the 5th, 10th, 15th, 20th and 30th postoperative days. The diameters of the hepatic arteries, portal veins and central veins which were located between 200μ-400μ from the anterior surface of the left posterior lobe of the liver were measured microscopically at the same postoperative days and changes of the size of the vessels were observed. Kupffer cells which contain the previously injected india ink particles were counted microscopically at the same postoperative days. The experimental results were summarized as follows; 1. Ligation of the proper hepatic artery in the rabbit caused massive necrosis of the liver and the gallbladder, and hydropic degeneration of the hepatocytes. But transient hydropic degeneration of the hepatocytes were observed in the portal vein stenosis group. 2. Blood flow in the hepatic artery and portal vein were closely related each other in the intrahepatic circulation. Diameters of hepatic arteries decreased (P<0.01), those of portal veins increased (P<0.005) and those of central veins decreased (P<0.001) in the proper hepatic artery ligation group. It means that occlusion of the proper hepatic artery was not compensated by increased flow in the portal vein and even caused stasis of flow in the portal vein. 3. Diameters of portal veins decreased (P<0.05), those of hepatic arteries increased (P<0.05) and those of central veins didn't change significantly (P>0.05) in the portal vein stenosis group. it suggests that reduced flow in the portal vein was compensated by increased flow in the hepatic artery. 4. The phagocytic activities of Kupffer cells were closely related to hepatic afferent blood flow. The activities were decreased continuously in the proper hepatic artery ligation group and transient decrease was noted in the portal vein stenosis group of rabbits (P<0.001).

悔軒의 耽羅雜詠 硏究

梁淳珌,金允中 제주대학교 1991 논문집 Vol.33 No.1

Cheju Island was one of the worst places of exiles. Many anexile suffered political ostracism had been sent to the remote island and there confined in the house enclosed with a hedge of thorny bushes. The prefecture of Taejong-hyon in Cheju was the typical rugged country for banishing. So for in the paper there have been analyzed the 22 pieces of "Tamna Chabyong(Miscellaneous Poems) written by Cho, Kwan-bin during his exile in Taejong. The summary is as follows: 1) Literature of exile is to be definded as a form of literature which shows direct experiences, emotions and spiritual lives of a writer and politician exiled owing to the periodical and political state of the Chosen Dynasty. Especially, literature of Cheju-exile was the literature formed by exiles banned to Cheju Island during their exile. 2) Hoehon (Cho, Kwan-bin's pseudonym) was exiled to Taejong by king Youg-jo for bearing a factical grudge against a minister. In the 7th year of King Yong-jo(1731), serving as Taesahon, he had impeached Yi, Kwang-jwa, the leader of the party of Soron, for Shinim Sahwa(The Shinim Calamity of Savants) by way of presenting a memorial to the king. 3) Hoehon spent the period of exile usefully, recognizing the social realities of the isolated island. Through his severe self-examination, he created remarkable works of literature of exile, confronting the difficulties of exile. 4) His literary works showed in "Tamna Chabyong" are charactered by successive construction from the 1st poem to the 22nd poem. The poems show his recognition of the island as his own experiential reality. He poetized the nature and the custom of the island itself, which has made a great contribution towards the expanding subject matters of Korean literature. While most subject matters of classical poetry had close relations to place names of China or Chinese folklore, the subject matters of "Tamna Chabyong" have relations to place names of exile and the island itself. In this respect the poems have a historic significance of Korean literature. 5) In the poems, there are described such as follows: first, the location of Tamna and Mt. Halla and myths; second, the history of Tamna and the longing for the King;third, the condition of the place of exile and the history of O-hyon; fourth, the ways of lives in Tamna and the custom; fifth, the presents to the King; last, the exile itself and emotions. Among them, there are specially well-described the living conditions of Cheju countrymen, the scenery of strange customs, an old peddler, the oranges and presents to the King, and the exile's miserable emotions. 6) While the characteristics of many other poems of this kind lie in the general composition of seclusion, escape, patriotic, sentiment, wailing ill fortunate and longing for the King, those of "Tamna chabyong" lie in the composition of such as the history, society, scenery and customs and manners of the place of exile. And it can be said that Hoehon'a'"Tamna Chabyong" had an influence on the same-titled poems composed by Cho, Chong-ch'ol(Chonghon), who was Hoehon's brother's grandson and was exiled to the same place in the years of King Chong-jo. 7) The whole poetry written in Hoehon-jip, a collecton of Hoehon's works, are supposed to be studied in general on the foundation of study on "Tamna Chabyong".

응급의료센터로 내원한 급성심근경색증 환자

정윤석,김준식,유인술,조준필 大韓應急醫學會 1996 대한응급의학회지 Vol.7 No.1

Early reperfusion can prevent myocardial necrosis, and clinical trials with reperfusion therapy demonstrating a significant reduction in acute myocardial infarction(AMT) mortality have dramatically changed the treatment paradigm for AMI. All patients with symptoms and ECG findings suggestive of AMI should be considered for treatment with thrombolytic agents. However, only a minority of AMI patients actually receive a thrombolytic therapy. Many patients are often excluded from treatment because they do not meet the criteria for age, duration of the chest pain, and a qualifying ECG. And late arrival at the hospital is a frequently cited reason for not giving a thrombolytic agent. To confirm the reason for not receiving an early reperfusion therapy, we obtained the data for the clinical characteristics, the time intervals between the symptom onset and the start of a thrombolytic agent infusion, the method of reperfusion therapy, the reason for not giving a thrombolytic agent and overall outcomes by retrograde chart review. During the 12-month study period between July 1994 and June 1995, 113 patients were finally diagnosed to AMI, who presented to Emergency Center of Ajou University Hospital in total 30,819 patients. The results were followings: 1. The average age was 59±12 years old, the ratio of male to female was 3.2:1. The direct visited patients to our hospital were 31 and the transfered were 82. 2. The chief complaints were chest pain(86.7%), dyspnea, dyspnea, and mental change. The common preceding diseases were angina pectoris(10 cases), old myocardial infarction(9 cases), congestive heart failure(2 cases) and typical chest pain but not diagnosed(23 cases). The risk factors were smoking(81 cases), hypertension (46 cases) and DM (22 cases). 3. 75 patients had arrived within 12 hours from symptom onset and 38 patients after 12 hours. 45cases (54.7%) were performed the reperfusion therapy ; 31 patients were taken the thrombolytic therapy by tissue-type Plasminogen Activator. 4. The most common reason for not receiving a reperfusion therapy was the time delay and the main was the patient/bystander factor. 5. 75.2%(85 cases) of the patients discharged with or without complications, 7.1% (8 cases) died, 10.6% (12 cases) discharged moribundly, and 7.1% (8 cases) discharged against advise. In conclusion, the time delay was the first reason for not receiving a reperfusion therapy in AMI patients. And the education for the AMI symptom and BLS (Basic Life Support) to the people, good EMS(Emergency Medical Service) system, early definite diagnosis and aggresive therapy may decline the mortality rate.

프로스타글란딘 E₁ 투영와 외과적 지연 처치가 당뇨 흰쥐의 횡복직근피판의 생존에 미치는 영향

조성필,전영준,송윤상,한기택 大韓成形外科學會 2002 Archives of Plastic Surgery Vol.29 No.6

한국에서의 스페인 연구 60년사 : 동향과 과제

최윤국,김현식,강필운,양성혜 조선대학교 국제문화연구원 2008 국제문화연구 Vol.1 No.1

Este trabajo trata de ojear la historia de las investigaciones con los temas de Espan~a realizadas en Corea durante unos 60 an~os. Para dicho objetivo elaboramos una base de datos de la bibliografi'a que abarca todos los libros, arti'culos, tesis sobre Espan~a publicados en Corea desde el an~o 1945 hasta el 2007. Basa'ndonos en el cual analizamos la tendencia del estudio espan~ol en Corea. La suma de los estudios realizados en Corea durante tal peri'odo llega a ser 3,072 ejemplares, entre los cuales, los libros son 1,131(36.82%), las tesis, 612(19.92%) y los arti'culos acade'micos, 1,329(43.26%). Analizando los datos, primero, esbozamos co'mo se han cambiado por las etapas el nu'mero de los frutos de las investigaciones espan~olas en Corea a lo largo del tiempo, segundo, nos centramos en la transicio'n por peri'odo del porcentaje que ocupan cada campos de estudio. por ejemplo, en poli'tica, economi'a, cultura, sociedad, historia, geografi'a, lingu¨i'stica y literatura, turismo, etc. y el cambio de los contenidos de estudio en cada campos segu'n las etapas del tiempo. Una peculiaridad destacable en el resultado del ana'lisis es que han estimulado la investigacio'n sobre Espan~a en Corea unos eventos histo'ricos en ambos pai'ses como la imigracio'n de coreanos a los pai'ses hispanohablantes, la poli'tica de la campan~a de exportacio'n por parte del gobierno coreano, la adhesio'n de Espan~a en la CE en 1986, los Juegos Oli'mpicos en Seu'l en 1988, la asociacio'n de Corea tanto en la OCDE como en la ASEM en 1996, la Copa Mundial de Fu'tbol en Corea en 2002, etc.

고장식염수가 토끼 빈창자 점막 산호성 과립세포의 미세구조에 미치는 영향

문정석,윤상필,정윤영,허영,장인엽,김종중 朝鮮大學校 附設 醫學硏究所 1998 The Medical Journal of Chosun University Vol.23 No.1

This experiment was performed to study the influence of hypertonic saline on the production of the secretory granules by the cellular organelles of the jejunal Paneth cells of the rabbit fed on the 3 % hypertonic saline. The jejunal mucosae of the experimental rabbits were removed partially in the upper one third of the jejunum and fixed in 2.0% glutaraldehyde for 2 hours, followed by 1% osmium tetroxide fixative for 2 hours. Then they were embedded in epon mixture, cut with ultramicrotome and done uranyl acetate-lead citrate double stain, and observed with JEM100 CX Ⅱ electron microscope. Observed results were as follows: 1. The number of secretory granules of a higher electron density was gradually increased as a whole in the course of time after feeding on the hypertonic saline. 2. After feeding on the hypertonic saline, secretory granules of various sizes with a higher electron density mostly occupied the supranuclear region of Paneth cells, but a few secretory granules of various sizes with low electron density were observed. 3. After feeding on the hypertonic saline, the Goigi complex, the mitochondria and the rough surfaced endoplasmic reticula were gradually figured, especially the cisternae of the rough surfaced endoplasmic reticula displayed polyhedral shapes. 4. Considering the above findings, following the feeding on the hypertonic saline, the function of the jejunal Paneth cells was influenced and secretory granules of various sizes with a higher electron density were more abundant as compared with those of a lower electron density. From the above results, it was considered that the Golgi complex, the mitochondria and especially the rough surfaced endoplasmic reticula were activated to maintain homeostasis. As a result of that, the production and concentration of secretory granules were prominently observed.

흰쥐 올리브소뇌계통의 발생에 따른 IGF-I에 대한 면역조직화학적 연구

장인엽,윤상필,정윤영,김종중,문정석,김영택,장영훈 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.4

고장식염수가 토끼 빈창자 점막 산호성 과립세포의 미세구조에 미치는 영향

문정석,윤상필,정윤영,허영,장인엽,김종중 조선의대 1996 The Medical Journal of Chosun University Vol.21 No.2

Carbofuran이 청개구리 배아 발달에 미치는 영향

고선근,윤필상 호남대학교 2008 학술논문집 Vol.29 No.2

The Frog Embryo Teratogenesis Assay-Xenopus(FETAX) protocol has recently been adopted as a valuable tool for evaluating the embryotoxicity of chemical toxicity and environmental contaminants in frogs. In this experiment, embryotoxicity of the Pb2+ was determined in Korean frog, Hyla japonica using the FETAX protocol. The percentage of mortality as well as the percentage of malformed larvae was investigated by probit analysis. The 96-h LC50 of 23.9 ㎎/ℓ and EC50 of 13.8 ㎎/ℓ, a TI of 1.73 was derived; indicating that Carbofuran is to be considered a teratogenic compound. From the above results, it reveal that Carbofuran in this experiment suppressed the development of embryos at relatively low concentration. Therefore, the Hyla japonica embryo teratogenesis assay system can be used as a useful tool to evaluate the toxicity of the pollutants in environment.