항균성 펩타이드인 Mastoparan B의 살조효과

서정길,김찬희,배윤정,문호성,김근용,박희연,윤호동,김창훈,변대석,홍용기,박남규 한국어병학회 2003 한국어병학회지 Vol.16 No.3

Mastoparan B (MPB)는 벌독으로부터 정제된 양친매성α-helical 구조를 취하면서 14개의 아미노산 잔기로 구성된 염기성 항균성 펩타이드로서 여러 가지 생물막과 작용한다. 본 연구에서는 우리 나라 연안의 적조 (HABs, harmful algal blooms)를 일으키는 4종의 적조생물 (Alexandrium tamarense, Chattonella catenatum)에 대한 MPB의 살조효과를 조사하였다. MPB의 4종의 적조생물에 대한 살조효과는 31.3㎍/㎖에서 세포의 lysis또는 ecdysis와 같은 형태로 현미경으로 관찰할 수 있었다. 또한 MPB는 C. marina 및 C. polykridorides에 대해서 A. tamarense와 G. catenatum보다 더욱 강한 살조효과를 나타내었다. 이러한 MPB의 HABs에 대한 살조효과연구는 새로운 살조물질을 개발하기 위한 자료가 될 것으로 생각된다. Mastoparan B (MPB), an antimicrobial cationic peptide isolated from the venom of the hornet Vespa basalis, is a basic amphipathic a-helical peptide composed of fourteen amino acid residues. In this study, we have investigated the algicidal effect of MPB against hatmful algae blooms (HABs) casative Alexandrium tamarense, Chattonella marina, Cochlodinium polykrikoides and Gymnodinium catenatum. The algicidal effect of MPB showed in the concentration of 31.3 ㎍/㎖ to 500 ㎍/㎖ against 4 HAB species and observed cell lysis or cell ecdysis by microscopy. MPB reacted more sensitive to C. marina and C.polykrikoides than A. tamarense and G. catenatum. The algicidal study of MPB against HABs will provides much insight into development of new algicidal substances.

新生國의 政治參與의 政治發展

尹龍熙 慶北大學校 1982 論文集 Vol.33 No.-

The main purposes of this paper are to present limitation factors and improvement plans of the political participation and political development, how political participation influences political development in the emerging countries. Political participation is activies that a people express their opinion and influences the process of national policy decision-making individually or in a group, and political development is increase of political system ability, and the increase of political system ability can be accomplished through increase to political participation, legitimacy and efficiency of the political system. In the other express, political development means institutionalization of political system and political participation. Accordingly, desirable political development can be achieved in harmony and balance of participation and efficience in the political system, especially political development can be realized by institutionalization of political participation. The main contents of this paper are summarized as follow; 1) political participation and political development; (1) definition of political participation and political development (2) relation of political participation and political development (3) patterns of political participation crises 2) The limitation factors of political participation and political development in emerging countries are: (1) the weakness of social-culture and economic structure (2) weakness of political system and political parties (3) undemocratic of political leaders, elite and people 3) The plans of improvement on political participation and political development in emerging countries are: (1) improvement of social-culture and economic structure (2) formation of participant political culture through political socialization (3) strength of political system through political participation (4) local self-government operation (5) differentiation and autonomy of interest group (6) institutionalization of political parties (7) independence and autonomy of political communication (8) increase on democratic idea of political leaders and a people 4) Conclusion

第1共和國 政黨의 構造와 機能

尹龍熙 경북대학교 사회과학연구소 1985 社會科學硏究 Vol.1 No.1

The political system of The First republic was authoritarian system of single man and the level of institutionalization was very low, the party system also not well organized and it remain as a Kind of tempory coalition around the indivicual elites Parties Functioned not by is systemic structure but by the personal Leadership so the party structure of the First Republic was weak and it did not function well as a political party This Article describe the elite party system of the First Republic an its structual and functional weakness At able contents of this paper are summarized as Follow: 1) weak of political system 2) structure of political parties ① weak of political parties foundation ② formation and strucure ③ formation and sturcture of opposition 3) Function of political parties 4) pathology of person an elite parites

뇌졸중 후 반사성 교감신경성 위축증후군에서체표온도의 정량적 분석

신용일,양선호,서정환,김연희 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.3

政治社會化와 環境

尹龍熙,成章煥 慶北大學校 東洋文化硏究所 1982 東洋文化硏究 Vol.9 No.-

This paper intends to explain what political socialization is and to know the environment of the political socialization. Especially, this paper accounts for the environment which affects the political socialization of people, and examines family, school, peer group, and mass communication as the environment of the political socialization. In order to bring up the sound democratic citizens, reasonable political socialization is to be done. For three points, each citizen has to learn good and high political social norms. The contents of this paper are as follows; 1) Preface 2) Political Socialization and Poiltical Culture 3) Political Socialization and Environment 4) Political Socialization in Korea 5) Conclusion

中共의 權力鬪爭樣相

尹龍熙 경북대학교 법정대학 1979 法大論叢 Vol.17 No.-

뇌손상 후 인지기능장애에 대한 메칠페니데이트의 효과-이중맹검 위약대조 연구-

김연희,나승용,신용일,서정환 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.4

政治發展과 政黨 및 行政發展의 關係

尹龍熙 慶北大學校 東洋文化硏究所 1981 東洋文化硏究 Vol.8 No.-

The main purposes of this paper aim to define the concept of the political development and to examine the correlation of the political development with the parties and the administrative development. The political development has the various meanings. But in this paper we define that the political development is the balanced development between the parties development and the administrative development together. In other words, the political development means that input functions in the political system are increased through the political parties development and the administrative development. In the political development, the input function can he increased through the political parties development and output function can be increased through the administrative development. For this reason, the perfect meanings of the political development can be achieved through the balanced development and the close correlation of the political parties development with the administrative development. In the political development, the crises faced with common are identity crisis, legitimacy crisis, participation crisis, distribution crisis, penetration crisis, integration crisis etc. Also these can be only achieved through the balanced development of the political parties development and the administrative development. Therefore, in the political development, there are the close correlations among the political development and the political parties development, the political development and the administrative development, and the political parties development and the administrative development interdependent. The main contents of this paper summarize as follows; 1) forward 2) the concept of the political development 3) the relation of politics and administration 4) the relation of the political development and the political parties development 5) the relation of the political development and the administrative development 6) the correlation of the political parties development and the administrative development 7) conclusion.

니켈 촉매를 이용한 탄소-탄소 결합반응

윤희성,박광용 중앙대학교 생산공학연구소 1997 생산공학연구소 논문집 Vol.6 No.2

탄소와 탄소를 결합시키는 반응은 유기합성에서 매우 중요한 도구중의 하나이다. Alkyl metal reagents와 aryl halides간의 cross-coupling reactions 에는 nickel 또는 palladium complexes가 촉매로서 효과적으로 사용되고 있다. 특히 primary alkyl Grignard reagents와 aryl halides간의 반응인 경우에는 NiCl 탄소와 탄소를 결합시키는 반응은 유기합성에서 매우 중요한 도구중의 하나이다. Alkyl metal reagents와 aryl halides간의 corss-coupling reactions 에는 nickel 또는 palladium complexes가 촉매로서 효과적으로 사용되고 있다. 특히 primary alkyl Grignard reagents와 aryl halides간의 반응인 경우에는 NiCl₂L₂ 형태의 촉매에 의해 가장 능률적으로 반응이 진행되는 것으로 알려져 있다. 본 연구에서는 alkyl metal reagents로서 neopentyl Grignard reagents를 사용하여 다양한 aryl halides와의 cross-coupling reaction을조사하였다. 반응의 촉매로서는 (dppf)NiCl₂가 사용되었다. Neopentyl group은 primary alkyl 형태로서 일반적으로 반응성이 적고, 구조적으로 steric hinderance의 영향 때문에 탄소-탄소 결합 형성이 어렵다고 알려진 구조이다. 본 연구에서는 두 종류의 neopentyl Grignard reagents와 네 가지의 aryl halides의 조합으로 부터 모두 8 종류의 생성물들을 우수한 수율로 얻을 수 있었으며, 이 생성물들을 GC-Mass를 이용하여 분석하였다. Carbon-carbon bond-forming reactions is one of the most useful tools in the area of organic synthesis. Cross-coupling reactions of alkyl metal reagents with aryl halides are effectively catalyzed by nickel or palladium complexes. It is especially well known that primary alkyl Grignard reagents couple with aryl halides most efficiently in the presence of NiCl₂L₂ as catalyst. The cross-coupling reactions of neopentyl Grignard reagents, which were used as alkyl metal reagents, with various aryl halides were investigated in this research. (dppf)NiCl₂ was utilized as the catalyst for these coupling reactions. Neopentyl group which is the primary alkyl group has been reported as the structure with the poor reactivity in most cases and the difficulty forming carbon-carbon coupling due to steric hinderance. From the combination of two neopentyl Grignard reagents and four aryl halides, eight cross-coupling products were prepared in good yields and analyzed by GC-Mass.

거대 관동맥류에 병발한 급성 심근 경색증 1예

윤혁준,김기식,허승호,박남희,조용원 대한순환기학회 2002 Korean Circulation Journal Vol.32 No.8