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      • 인체 심근막 구성섬유의 배열 양상

        이용덕 대구보건전문대학교 2006 대구보건대학 論文集 Vol.26 No.-

        This study examined the running patterns of deep fascia around muscles in a human cadaver. After the skin and superficial fascia were removed, the holistic fascia arrangement was investigated with the naked eye. In order to make an observation, the interconnection of fasciae on both sides and muscles were lifted. To make an estimation of running direction and tension of the subject fasciae of each body part, epimysium along with muscle fibers of the subject muscles were held and lifted with tweezers. The running direction and tension correlation of the deep fascial fibers were observed parallel to the muscle fibers of the subject muscles. In the back, four rhomboid shape fascial profiles were observed around the vertebral column. The rhomboid profiles are composed of a fascia of trapezius, a fascia of latissimus dorsi, a fascia of Michaelis rhombod, and an innominated rhomboid, which were located between a fascia of trapezius and a fascia of latissimus dorsi. Upon observation of the connection of fascial fibers, they appeared with a thin and loose formation between muscles, appeared with a thin and dense formation between a muscle and soft tissue around the bone, and appeared with a thick and loose formation between muscle groups.

      • KCI등재

        운동훈련이 흰쥐 노화심근에 미치는 영향 : I. 장기간 지구력 운동 훈련 I. Long Term Endurance Exercise

        이용덕,이상선,박원학 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 1996 Journal of biomedical laboratory sciences Vol.2 No.1

        장기간 반복 주행운동이 흰쥐의 심근에 미치는 효과를 규명하기 위하여 생후 3개월, 10개월 및 20개월된 흰쥐를 운동군과 대조군으로 대별하여 motor driven treadmill을 이용하여 Park등이 사용한 방법에 준해서 5개월간, 주 5일 20분간 운동을 시킨 후 심근의 조직 및 세포학적 변화를 관찰하고 심근 세포 내 미세구조 변화를 입체해석학적으로 비교 분석하였다. 연령 증가에 따라 장기간 반복운동이 흰쥐 심근 미세구조에 미치는 영향은 8, 15개월의 운동군과 대조군 사이에 뚜렷한 차이를 인정할 수 없으며, 15개월의 운동군에서 대조군에 비하여 변성된 사립체, 리소조옴, 지방적, 공포, 노화색소 등이 증가하는 경향이 있었다. 25개월 운동군은 같은 연령 대조군에 비하여 근원섬유 수축대, 근원섬유 소실, 윤반분리, 세포간질 증식, 핵의 변성, 교원섬유 근섬유내 침입 등 매우 심한 변화를 보였다. 조직상에 나타나는 early lipofusin과 미세구조상에 나타나는 노화색소는 8, 15개월의 운동군과 대조군 사이에 유의한 차이는 없었으며, 25개월 운동군은 같은 연령 대조군에 비하여 유의한 차이로 증가하였다. Glucose-6-phosphatase 활성도 8, 15개월군에서 운동군과 대조군에서 모두 활성이 높았으며 25개월의 대조군과 운동군에서는 모두 활성이 거의 나타나지 않았다. 미세구조 변화를 입체해석학적으로 분석한 결과 8,15개월의 대조군과 운동군에서 체적 밀도의 모든 항은 양군사이에 유의한 차이가 없었다. 25개월에서는 세포간질이 대조군에 비하여 운동군이 유의한 증가를 나타내었고, 근원섬유는 유의한 차이는 없지만 증가하는 경향을 보였으며, 사립체는 대조군에 비하여 유의한 감소를 나타내었고 근형질세망의 체적밀도는 감소하는 경향을 보였다. 사립체와 근원섬유 비는 8개월 운동군에서 유의한 차이는 없지만 대조군에 비하여 높게 나타났으며, 15개월의 운동군과 대조군 사이에서는 차이를 인정할 수 없었다. 그러나 25개월 운동군은 대조군에 비하여 유의한 차이로 감소하였다. 연령증가에 따른 사립체 내막 표면밀도와 사립체수는 대조군과 운동군 사이에는 유의한 변화는 없었다. 본 연구의 성적을 검토한 결과 젊은층(3개월군)과 중령층(10개월군)의 흰쥐에서는 반복된 지구력 운동이 심장에 미치는 역효과를 인정할 수 없었으며 젊은층의 흰쥐에서는 오히려 심장기능 강화를 보이는 경향이 나타났으며, 노화층(20개월군)에서 운동군에서는 스트레스로 작용하여 심장기능의 저하를 초래 하였다고 생각된다. There is considerable current interest in the effect of regular vigorous exercise and in particular endurance-running as a possible measure in improving myocardial function. Some data indicate that the aging heart may actually suffer from vigorous endurance exercise. On the contrary, appropriate exercise in aged animals improves myocardial function and aerobic energy metabolism. So far there is relatively little data to indicate that endurance exercise is in fact beneficial in improving myocardial function or damaging to heart of aged animals. The present investigation aimed to study the possible effect of a long range treadmill training program on the heart in aging rats. Male rats aged 3, 10, and 20 months were divided at random into a control (sedentary) and an exercise group. The training group was exercised for 5 days a week on an automated treadmill for 20minutes at 18m/min over a period of 5 months. The exercise regimen of our experiments did not cause any significant changes in the tissues and ultrastructural as compared with sedentary age-matched control. Tissues and ultrastructures of myocardial cells in trained group aged 8 months are intact and well organized as well as sedentary control group. Age associated tissue and ultrastructural changes of trained group aged 15 months included : an increase in transformed mitochondria, vacuoles, lysosomes, lipid droplets and early lipofuscin. But the trained heart did not show significant difference in tissue and ultrastructural properties from those of sedentary controls. Endurance-trained group aged 25 months showed significant qualitative tissue and ultrastructural difference as compared with age-matched controls. In addition to those found in 25 months control group, focal necrosis, myofibril fraying, hypercontraction band, seperation of intercalated discs, degenerating nucleus and infiltration of collagenous fiber into myocyte were noted in trained 25 months group. The stereological examination of the micrographs disclosed no significant difference in the myofibril, mitochondrion, sarcotubule and interstitium volume density and surface density of mitochondrial cristae and numerical density of mitochondria between trained and control group aged 8 and 15 months. In the trained 25 months group, significant increase in volume density of interstitium, lipofucsin granule were shown as compared to untrained agematched control. On the other hand, significant decrease in mitochondrion volume density was shown. The myofibril volume density did not differ between trained and control group although trained group showed slight increase. From the data obtained, a reduced mitochondria/myofibrils ratio was found in trained rat heart aged 25 months and there was no difference between trained and control rat aged 15 months. But a slight but not significant increase was found in the trained group aged 8 months as compared with same age control group. Such increase in the ratio in young animals is considered to be of great importance to cardiac pumping and adaptability. Whereas such adaptations don't seem to occur in aged heart muscle. This study proposed that repeated endurance exercise do not cause any significant qualitative and quantitative ultrastructural change of heart muscle in young(3months) and adult(10months) suggesting that the heart is able to adapt to the exercise. On the contrary, the repeated endurance exercise stress may actually induce degenerative changes in the aged heart muscle(20months).

      • KCI등재
      • 資産性 投資事業의 效果的 管理를 위한 經營情報시스템의 設計

        崔德圓,崔相萬,洪永植 成均館大學校 1980 論文集 Vol.28 No.-

        Most industries have several projects to undertake which fall into the category of capital investments. But the general tendency of their economic analysis has been confined to a project by project basis. This tendency made it very difficult to configurate overall possible impacts upon the value of a firm, and upon the future financial structure that may be produced from the performance of a certain set of selected project alternatives. This thesis attempts to resolve these shortcomings by adopting the concept of integrated management information system. For this purpose a data base schema was constructed to facilitate the systematic processing of capital investment information. From the cash flow information a desirable debt ratio (DDR) was determined to find the amount of debt that can be financed to each project under specified risk level. The DDR model, when applied with the 0-1 integer programming model, plays an important role in the selection of optimum project-mix that will keep the firm in healthy financial position throughout its planning horizon. Another important achievement from this study is that it was made possible to derive various kinds of expected financial ratios over the forthcoming time domain of top management's concern, while the conventional financial ratio analysis has been restricted to the past.

      • KCI등재

        한국인에서 Quadruplex PCR을 이용한 8종류 상염색체 STR 유전좌의 다형성 분석

        장영길,김기범,신창호,이숭덕,이윤성,이정빈 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

        Two quadruplex PCR reactions were designed for 7 tetrameric (D3S2406, D4S2368, D5S818, D7S821, D9S925, D13S317, D19S253) and one trimeric (D6S1043) short tandem repeats loci to study the allele frequency and the applicability of genetic variation in these loci in forensic case works. For 310 unrelated Koreans DNA was isolated from peripheral blood using phenol/chloroform method. Quadruplex I was consisted of D4S2368, D6S1043, D7S821, D9S925 and quadruplex II D3S2406, D5S818, D13S317, D19S253. The amplified products were analyzed by 5% polyacrylamide gel electrophoresis followed by silver staining. The heterozygosity in each loci ranged 92.91-66.13%, and PD(Power of Discrimination) was above 085 in each loci. Every loci except D6S1043 followed hardy-Weinberg expectation. The cumulative PI was low as 1.65×10-10. Two mutations were noted, one in D19S253 and the other in D9S925 among 234 gametes. With these results above eight STR loci studied here preyed to be highly polymorphic enough to be used in forensic field. This study provides valuable population data in these loci for Korean.

      • 200m 달리기시 곡선 구간과 직선 구간 동작의 운동학적 변인 비교 분석

        김용운,정철수,은선덕,이영석 한국운동역학회 2000 한국운동역학회지 Vol.10 No.1

        본 연구는 단거리 달리기(200 m)의 곡선 구간과 직선 구간의 동작을 비교 · 분석하여, 운동학적 변인의 차이를 규명하고, 곡선 구간의 동작 메카니즘에 대한 기초적인 정보를 제공하기 위해, 서울체육고등학교의 100 m 및 200 m 달리기 선수 5명을 대상으로 하여, 3차원 영상 분석법을 통하여 동작을 분석하였다. 본 연구에서 도출된 결론은 다음과 같다. 1. 신체중심의 높이는 직선 구간이 곡선 구간보다 높았으며, 신체중심 변위의 변화는 곡선 구간에서 더 컸다. 2. 신체중심의 수평속도는 곡선 구간이 직선 구간보다 컸으며, 곡선 구간에서 내측 스트라이드 국면이 외측 스트라이드 국면보다 컸다. 3. 신체중심의 수평 측면속도는 평균값에서 곡선 구간과 직선 구간이 차이가 없었으나, 속도의 절대값에서는 곡선 구간이 직선 구간보다 컸다. 4. 곡선 구간 내, 외측 스트라이드 국면의 이지, 착지시 접선속도는 차이가 없었다. 5. 스트라이드 길이는 곡선 구간의 외측 스트라이드가 가장 길었으며, 직선 구간, 곡선 구간의 내측 스트라이드 순서로 길었다. 6. 스트라이드 빈도는 곡선 구간과 직선 구간에서 차이가 없었다. 7. 상체 전경각의 평균값은 곡선 구간과 직선 구간에서 차이가 없었으나, 범위는 곡선 구간이 직선 구간보다 컸다. 8. 상체 측경각은 평균값에서 곡선 구간이 직선 구간보다 컸으나, 범위는 차이가 없었다. 9. 상완의 운동범위는 곡선 구간과 직선 구간에서 차이가 없었다. 10. 무릎거양각은 곡선 구간이 직선 구간보다 운동범위가 컸다. 이상의 결과, 단거리 달리기의 곡선 구간에서 직선 구간과는 차별화된 수행 형태를 보였으며, 내, 외측 스트라이드 간에도 상이한 수행 형태를 보였다. This study was conducted to make a comparative analysis of running motion and to examine the differences of kinematice in curved and straight track portion during the 200m sprinting. In this study, five skilled male sprinters of high school served as subjects. The running motions were analyzed using the method of three-dimensional cinematography The conclusions of this study were as follows. 1. Height of the center of gravity in straight portion was higher than that in curved portion, but displacement of the center of gravity in curved portion was higher than that in straight portion. 2. Horizontal velocity of the center of gravity in curved portion was faster than that in straight portion, and in curved portion that of left stride phase was faster than that in fight stride phase. 3. There was no difference in mean value of lateral component of horizontal velocity between both portions, but absolute value of that in curved portion was faster than that in straight portion. 4. There was no difference in tangential velocity at the instant of touchdown and takeoff of both strides on curved portion. 5. Stride length in right stride of curved portion was the longest, and next to that, that of straight portion was, and left stride of curved portion was the shortest. 6. There was no difference in stride frequence between curved and straight portion. 7. There was no difference in mean value of forward lean angle between both portions, but active range of that in curved portion was larger than that in straight portion. 8. Mean value of inward lean angle in curved portion was larger than that in straight portion, but no difference in active range of that between both portions. As the conclusion of this study, it was clear that there were significantly different running patterns between curved and straight portion, and between left and right stride of curved portion.

      • 최대 운동후 면역 기능의 반응

        최용어,박덕배 韓國體育大學校 1998 論文集 Vol.21 No.-

        This study rearches how graded maximal exercise has an effect on the university handball atheletes group and the general individuals group before exercise, after exercise and in the recovering two hours through cellic immunoreaction. Graded maximal excercise has been done by means of treadmill, applying Bruce protocol which was practised by male university students to see what difference there is between the athelete group and general individual group. The following is the results of comparing and analyzing the immunoreaction of the drawn blood before exercise, after exercise and in recovering two hours. 1. When graded maximal exercise is done, total white blood cells increase more after exercise for both the athlete group and the general individual group. And they are inclined to increase continously in the recovering two hours. Statistically there is no meaningful difference between them. 2. When graded maximal exercise is done, neutrophils increase more after exercise than before exercise for both the athlete group and the individual group. And they are inclined to increase continously in the recovering two hours. Statistically there is no meaningful difference between them. 3. When graded maximal exercise is done, lymphocytes increase more after exercise for both the athletes group and the general individuals group. For the athletes group, lymphocytes increase continously in the recovering two hours. But for the general individuals group, lymphocytes are inclined to come to stability as usual. Statistically there is no meaning difference between them. 4. When graded maximal exercise is done, monocytes increase more after exercise than before exercise. And they continue to increase in the recovering two hours for the athletes group. Monocytes decrease after exercise, but they are inclined to increase in the recovering two hours. Statistically there is no meaningful difference between them. 5. When graded maximal exercise is done, natural killer cells increase more after exercise than before exercise. And they continue increasing in the recovering two hours for both the athletes group and the general individuals group. Statistically there is no meaningful difference between them. All the above results being considered, the graded maximal exercise make immune cells change a lot. It is suggested that especially lymphcytes and natural killer cells can be a factor which enforces human body immunity function.

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