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노희삼,홍사용,류지욱,이춘우 공주대학교 기초과학연구소 2000 自然科學硏究 Vol.9 No.-
광연대 측정의 기본 원리와 몇 가지 응용을 기술하였다. 광 연대측정은 결정체의 결함이 외부 에너지원으로부터 자극을 받아 여기된 전자를 구속할 있으며 구속된 전자는 열이나 빛과 같은 외부 자극에 의해 바닥 상태로 전이되며 이 때 빛을 발생하는 원리를 이용한다. 광연대 측정은 몇 십년 단위부터 몇 십만년 단위의 연대 측정이 가능하며 고고학적 지질학적 연구에 적합하다. The basic theory of the luminescence dating and its applications is described. The optical dating utilizes that crystal defects can trap electrons excited by natural radioactivity and give luminescence when external stimulat'ion such as light and heat, is applied. The range of the optical dating is from a few decades to hundreds of thousand years, which is useful for both archeological and geological dating. There are some commercially available systems, which automate the measurements.
Poster Session : IGF2/IGF2R system is a novel regulator of endothelial progenitor cell homing
( Yong Sun Maeng ),( Yeon Sook Choi ),( Seung Sik Rho ),( Ji Hye Kim ),( Yong Hak Kim ),( Jeong Ki Min ),( Ja Young Kwon ),( Yong Won Park ),( Young Myeong Kim ),( Young Guen Kwon ) 한국생화학분자생물학회 (구 한국생화학회) 2006 생화학분자생물학회 춘계학술발표논문집 Vol.2006 No.-
노용관 ( Yong Kwan Rho ),유광호 ( Kwang Ho Yoo ),김지영 ( Ji Young Kim ),이갑석 ( Kap Sok Li ),서성준 ( Seong Joon Seo ),홍창권 ( Chang Kwun Hong ),송계용 ( Kye Yong Song ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.12
Spindle cell lipoma is a benign, subcutaneous neoplasm typically located on the neck, back and shoulder of men. Pseudoangiomatous spindle cell lipoma is a rare variant of spindle cell lipoma that is characterized by non-vascular branching spaces. A 64-year old man presented with 2 masses on the abdomen. Although 1 tumor had a very low fat component, it could be histologically diagnosed as pseudoangiomatous spindle cell lipoma due to CD 34 positive spindle cells, ropey collagen and blood vessels. We report a case of pseudoangiomatous spindle cell lipoma on the abdomen, which was diagnostically difficult due to a scanty fat component. (Korean J Dermatol 2008;46(12):1644∼1647)
노용지(Yong Ji Rho),이규석(Kyu Suk Lee),송준영(Joon Young Song) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.6
Transforming growth factor beta(TGF-p), initially identified in vlatelet extracts by virtue of its ability to confer anchorage of independent growth and a necplastic phenotype on mesenchymal cells, has subsequently been identified as a potent inh bit or of proliferation in most cells of epithelial origin. The family of TGF-p peptides is currenly onsisted of four subtypes (TGF-pl, p2, p3, p4). Tkiey are initially translated very larged are urssors of approximately 390 amino acids and produced by a wide variety of cell type. iricluding normal cells and tumor cells. TGF-ps promote deposition of extracellular matrix compcineits, facilitate remodeling events during embryonic development, and suppress immune ce 1 fimetion during the inflammatory process. Several nutaneous diseases are characterized typxcessive and progressive fibrosis of the dermis anil subcutaneous tissues. Prominent amon these disorders are progressive systemic sclerosi(PSS) and generalized morphea(GM), is well as the recently described syndrome of diffuse fasciitis eosinophilia(DF), also known; Shulmans syndrome. The hallmark of the pathologic alteration in these disorders is the excessive deposition of collagen and other connenctive iissues. Macromoleculse in the aerriis and/or the subcutaneous and fascial strutures often accompanied by variable degress of hronic inflammatory cell infiltrates. Now we have examined the expression of TGF-b1 mRNA using of northern blot hybridization with specific sequenced cDNA probe in the normal curltured fibroblasts, placental tissues, and fibrosarcorna derived tumor cell line(HT1080). We found that the size of TGF-b mRNA of each specimen was 2.5kb and theres no alteration of its quality. (Kor J Dermatd 1992;30(6):824-829)
노용지(Yong Ji Rho),이규석(Kyu Suk Lee),송준영(Joon Young Song) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.3
A 19-month old male patient developed mutiple, firm, plum-colored, finger tip to chestnut sized nodules on the left cheek, right preauricular area, both elbow joints, and right wrist. On physical examination, a right cervical lymph node was palpable. Histology from one of the nodules revealed a diffuse infiltration of atypical, hyperchromatic, polymorphous lymphocytes in the dermis and subrutaneous fat. Bone marow aspiration, chest X-ray, ultrasonogram, and computerized tomogram were performed revealing bone marrow and lymph node involvement. The patient was treated with a POG @8617 schedule. Skin lesions markedly improved after one cycle regimen. We present a case of diffuse, ponrly differentiated, malignant lymphocytic lymphoma in the early childhood. (Kor J Dermatd 1992; 30(3): 422-427)
노용관 ( Yong Kwan Rho ),김연진 ( Yeon Jin Kim ),안지영 ( Ji Young Ahn ),서성준 ( Seong Jun Seo ),홍창권 ( Chang Kwun Hong ),송계용 ( Kye Yong Song ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.11
Adult xanthogranuloma is nearly indistinguishable from juvenile xanthogranuloma characterized by yellow-red nodules on the skin, normal lipid findings and the proliferation of xanthomatizied histiocytes with foamy Touton cells, histologically. But unlike juvenile xanthogranuloma, there is no visceral involvement, spontaneous regression and more solitary lesions. Multiple adult xanthogranulomas are rare entities that present more spontaneous involution. Here we report a case of a 39-year-old patient with multiple xanthogranulomas which developed on the face, trunk and extremities. Diagnostic workup revealed normal lipid profile and no extracutaneous manifestations. (Korean J Dermatol 2007;45(11):1176∼117)
에 대한 혈청 IgG 역가로 위 - 십이지장질환을 감별진단할 수 있는가 ?
최지용(Ji Yong Choi),김학양(Hak Yang Kim),윤덕형(Duck Hyoung Yoon),노승혁(Seung Hyuk Rho),김수진(Soo Jin Kim),이자영(Ja Young Lee),백광호(Gwang Ho Baik),김억(Auk Kim),이진헌(Jin Heon Lee),김용범(Yong Bum Kim),김우중(Woo Joong Kim),유 대한소화기학회 2002 대한소화기학회지 Vol.39 No.3
Background/Aims: Among the diagnostic methods to detect Helicobacter pylori (H. pylori) infection, serological test is a noninvasive, safe, and inexpensive method in clinical practice. This study was performed to determine whether the titer of anti-H. pylori IgG antibody was correlated with endoscopic findings of gastroduodenal diseases, gastric ulcer stage, and age. Methods: Two hundred and eighteen patients who were H. pylori positive by serological method and received gastroduodenal endoscopy were enrolled. All patients had the titers of anti-H. pylori IgG antibody >300 U/mL. We compared the antibody titer according to gastroduodenal diseases, peptic ulcer stage, and age group. Results: There was no statistically significant difference between serum anti-H. pylori IgG antibody titer according to gastroduodenal diseases (chronic gastritis, 999.8±120 U/mL; gastric ulcer, 1043±155.6 U/mL; duodenal ulcer, 1018.5±121.9 U/mL; gastric cancer, 1351±266 U/mL; p=0.504). No significant difference in the anti-H. pylori IgG antibody titer was observed according to peptic ulcer stage (p=0.065) and age (p=0.791). Conclusions: The serum anti-H. pylori IgG antibody titer is not valuable in differentiating the gastroduodenal diseases. (Korean J Gastroenterol 2002;39:167-172)
노용지(Yong Ji Rho),최윤애(Yoon Ae Choi),이규석(Kyu Suk Lee),송준영(Joon Young Song) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.6
Background : Epidermolysis bullosa is a group of inherited disorcier characterized by blistering of the skin as a result of minor trauma. Objective : There exist very little epidemiologic data for most of the major and minor subsets of inherited epidermolysis bullosa in Korea. We look forward to obtaining basic data for the pathogenesis and treatment of epidermolysis bullosa. Methods : We performed 1st and 2nd trial of survey with the help of 28 dermatologic departments snd 28 pediatric departments of medical colleges and 14 dermatologic dipartments of general hospitals. Results : 68 cases were collected and classified by disease type, sex distribution, age distribution, and regional distribution. In disease type, 42 cases of EB simplex(62%), 8 cases of junctional type(12%), 10 cases of dominant dystrophic type(15%), 8 cases of recessive dytrcphic type(12%) were reported. In most cases males predominnted, but in dominant dystrophic type both sexes were equivalent. EB simplex, junctional type, RDEB were mostly developed in the 1st decade of life, dominant dystrophic type in the 2nd decade of life. In regional distribution, the number of pi tients was outstanding in large cities such as Seoul, Pusan, Taegu, Kwanju. Conclusion : Due to many limitations and shortage of techniques, this epidemiologic study may be notgood enough for the total estimated number of epidermolysis bullos. patients, prevalence rate, and therapeutic modalities. Furthe evaluation should be necessary next time, (Kor J Dermatol 1993;31(6):931-936)