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Xu, Ying,Zhang, Xiao-Hui,Pang, You-Zhi Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.11
TYR (Tyrosinase) and TYRP1 (Tyrosinase-related protein 1) play crucial roles in determining the coat color of birds. In this paper, we aimed to characterize the relationship of TYR and TYRP1 genes with plumage colors in Korean quails. The SNPs were searched by cDNA sequencing and PCR-SSCP in three plumage color Korean quails (maroon, white and black plumage). Two SNPs ($367T{\rightarrow}C$ and $1153C{\rightarrow}T$) were found in the coding region of TYRP1 gene, but had no significant association with plumage phenotype in Korean quails. The expression of TYR was higher in black plumage quails than that in maroon plumage quails. In contrast, the expression of TYRP1 was lower in black plumage quails than that in maroon plumage quails. This study suggested that the melanic plumage color in Korean quails may be associated with either increased production of TYR or decreased production of TYRP1.
Mechanical Performance of Prefabricated External Wall Panel under Horizontal Displacement
Ying Xu,Shuai-Ying Wang,Lei Chai,Cong-Cong Luo 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.11
In this paper, experiment and Finite Element Method (FEM) approaches are employed to study the mechanical performance of prefabricated external wall panel under lateral displacement. Tensile bond strength test and Z-shaped specimen direct shear test of the bonding interface of mortar to ceramsite concrete are performed, the normal and shear mechanical property of the interface is studied respectively. Scaled model test of prefabricated external wall panel under lateral displacement is then performed to obtain loaddisplacement curve, and mechanical behavior of prefabricated external wall panel in different stages is studied. Moreover, ABAQUS finite element analysis model for scaled model test panel is established based on previous study about bond interface and the results from experiment and FEM analysis are relatively consistent with each other. It is found that with the gradual increase in tangential contact stiffness of joint interfaces, the overall lateral stiffness of wall panels will approach complete joint consolidation conditions before the peak load. However, when the tangential contact stiffness of joint interfaces increases to a certain extent, there will be little change in initial lateral stiffness.
Ying Jiang,Chaoyang Guan,Xu Liu,Yushan Wang,Huaqin Zuo,Tian Xia,Peipei Xu,Jian Ouyang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.1
Doxorubicin (DOX) plays an important part in lymphoma treatment. However, various side effects on normal tissues restrict its clinical use. Nanocarriers connected by Gly–Phe–Leu–Gly (GFLG) can be equipped with the advantages of nanoparticles (NPs), their enhanced permeability and retention (EPR) effect, and surface modifiability. Nanocarriers can also be specifically enzymatically hydrolyzed by cathepsin (Cath) B, a kind of enzyme highly expressed in tumor cells. In this work, we proposed a novel drug delivery system comprising GFLG conjugated with copper sulfide (CuS) NPs loaded with DOX. The system, designated as CuS-GFLG-DOX, could be used for NP-based targeted combination chemotherapy. Results showed that the drug delivery system had an appropriate diameter, good dispersibility, high encapsulation efficiency and high drug loading. The system also exhibited an excellent targeting of lymphoma cells and an enhanced antitumor activity. The possible pathway to induce cytotoxic effects was Bcl-2/caspase-mediated apoptosis pathway. In conclusion, CuS-GFLG-DOX could precisely deliver drugs to lymphoma cells and could be a novel and promising therapeutic option for lymphoma.
Xu Ying,Chen Jing,Jiang Li-Yun,Qiao Ge-xia 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.1
A new species of the genus Aphis with stridulatory apparatus, Aphis gnetuma Qiao sp. n., feeding on Gnetum parvifolium which is a new host plant record for aphids from Guangxi, China is described. The new species is distinguished by a well-developed median frontal tubercle and body bearing white wax powder in life. The taxonomic position of this new species is supported by analysis results of COI and gnd genes. A key to Aphis species with stridulatory spines on the hind tibiae of apterous viviparous females is provided. The type specimens studied are deposited in the National Zoological Museum of China, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Xu, Xin-Fang,Gao, Yan,Xu, Shu-Ya,Liu, Huan,Xue, Xue,Zhang, Ying,Zhang, Hui,Liu, Meng-Nan,Xiong, Hui,Lin, Rui-Chao,Li, Xiang-Ri The Korean Society of Ginseng 2018 Journal of Ginseng Research Vol.42 No.3
Background: Temperature is an essential condition in red ginseng processing. The pharmacological activities of red ginseng under different steam temperatures are significantly different. Methods: In this study, an ultrahigh-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry was developed to distinguish the red ginseng products that were steamed at high and low temperatures. Multivariate statistical analyses such as principal component analysis and supervised orthogonal partial least squared discrimination analysis were used to determine the influential components of the different samples. Results: The results showed that different steamed red ginseng samples can be identified, and the characteristic components were 20-gluco-ginsenoside Rf, ginsenoside Re, ginsenoside Rg1, and malonyl-ginsenoside Rb1 in red ginseng steamed at low temperature. Meanwhile, the characteristic components in red ginseng steamed at high temperature were 20R-ginsenoside Rs3 and ginsenoside Rs4. Polar ginsenosides were abundant in red ginseng steamed at low temperature, whereas higher levels of less polar ginsenosides were detected in red ginseng steamed at high temperature. Conclusion: This study makes the first time that differences between red ginseng steamed under different temperatures and their ginsenosides transformation have been observed systematically at the chemistry level. The results suggested that the identified chemical markers can be used to illustrate the transformation of ginsenosides in red ginseng processing.
A RIF Based Mapping of RDB2RDF
Ying Chen,Zhuoming Xu,Yuyan Ni,Guangxu Cao,Shiqing Zhang 보안공학연구지원센터 2014 International Journal of Database Theory and Appli Vol.7 No.6
Mapping RDB to RDF (i.e., RDB2RDF) is the key to constructing the Semantic Web, hence has been an active research field during the last decade. Many technically heterogeneous RDB2RDF tools resulted in non-interchangeable and unreusable RDB2RDF mapping descriptions. In 2009, the W3C RDB2RDF Incubator Group Report once strongly suggested that the RDB2RDF mapping language be expressed in rules as defined by the W3C Rule Interchange Format (RIF) Working Group, because rules are an effective way to express mappings between information models, and RIF, as part of the infrastructure for the Semantic Web, is now a standard for exchanging rules among Web rule systems. This paper addresses the issue of RIF-based RDB2RDF mapping and proposes a database semantics-driven, RIF Production Rule Dialect (RIF-PRD) based mapping description approach. The work includes defining a set of generic RIF-PRD mapping rules for RDB2RDF, developing a prototype mapping engine called RIFD2RME (stands for RIF-based RDB2RDF Mapping Engine), and conducting case study experiments with the prototype. The experimental results indicate that the proposed mapping approach is achievable and effective.