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간경변증 환자에서 고암모니아혈증과 Helicobacter pylori의 연관성
김영수,최원,신현주,신용운,권계숙,이돈행,김범수,조현근,이재수,홍의수,박은재 대한소화기학회 1999 대한소화기학회지 Vol.34 No.3
Background/Aims: We examined the correlation between hyperammonemia and gastric Helicobacter pylori (H. pylori) infection in patients with liver cirrhosis. Methods: We studied 31 patients with liver cirrhosis and 34 normal controls. However, the cirrhotic group did not include patients who had a bleeding tendency or hepatic encephalopathy. We performed gastroscopy, obtained gastric juice (3-4 mL) and antral biopsy specimens, and examined the ammonia levels of blood and gastric juice in each group. Results: In the cirrhotic group, there was no difference in blood ammonia levels between the H. pylori- positive (HP+) and negative (HP-) groups. However, the ammonia levels of gastric juice in the HP+ group showed a tendency to be higher than those in the HP- group (p=0.0773). Child-Pugh scores in the HP+ group were significantly lower than those in the HPQ group (p= 0.0309). By multiple regression analysis, factors affecting the ammonia levels of blood were determined. They were age (coefficient 1.2462, p=0.0256) in the control group (r2=0.2821), and ammonia levels of gastric juice (coefficient 0.007417, p=0.0322) in the cirrhotic group (r2=0.3127). On the other hand, Child- Pugh scores (coefficient 12.508122, p=0.0883) indicated a slight correlation with the blood ammonia levels in the cirrhotic group. Conclusions: It seems that gastric H. pylori infection is associated with hyperammonia in patients with liver cirrhosis.
Quality evaluation using Paired Comparison and Median Rank Method
Kim Kye-Wan,Park Dong-Yeun,Yun Deok-Kyun 한국산업경영시스템학회 2002 한국산업경영시스템학회 학술대회 Vol.2002 No.추계
제품의 품질을 측정함에 있어 대부분의 방법들은 각각의 항목들에 대해 가중치를 부과하고 등급을 부여함으로써 실시된다. 그러나 고객의 입장에서는 단순한 등급보다는 객관적인 품질과 주관적 품질을 모두 고려한 보다 객관적인 품질평가지표를 원한다. 이 논문에서는 품질을 평가하는데 있어서 쌍대비교(Paired Comparison)와 메디안랭크(Median Rank) 방법을 사용하여, 상호 품질항목에 대한 쌍대비교를 통해 척도를 산출해 낸 후 해당되는 메디안 랭크를 부여함으로써 객관적 및 주관적 품질요소를 모두 반영한 통합된 품질평가 방법을 제시하고자 한다.
계승희,문현경,정해랑,황성희,김우선,문혜연 한국식생활문화학회 1995 韓國食生活文化學會誌 Vol.9 No.5
The purpose of the present study is to identify potentially hazardous factors which can contribute to the outbreak of foodborne disease and to represent more practical management methods in terms of environmental sanitation and facilities for the kitchen. 230 Korean-style restaurants in Seoul were assessed and analyzed by the restaurant total area. Facilities and sanitary check-lists were developed to evaluate the facilities and sanitary conditions of sampled restaurants. The sanitary condition of kitchen, guest room and other area were assessed by the sanitary score. The basic cooking machinery and utensil were properly facilitated but automation machinery were equiped below 10% sampled restaurants. The kitchen area were not properly sufficient to total area. Sanitary condition of kitchen, guest room, cooking appliance and stored foods were evaluated as the unsatisfactory state with potentially hazardous. Concrete guidelines should be made in terms of following item; establishment for the kitchen space expansion, facilities for the improvement of the working environment and sanitary condition of foods cooked. Additionally, it need to practice the effective education and training program for the foodservice manager and employees.
Kim, Yeon-Kye,Lim, Chi-Won,Yeun, So-Mi,Lee, Moon-Hee,Moon, Ho-Sung,Cho, Hyeon-Ah,Yoon, Na-Young,Yoon, Ho-Dong,Park, Hee-Yeon,Lee, Doo-Seog The Korean Society of Fisheries and Aquatic Scienc 2011 Fisheries and Aquatic Sciences Vol.14 No.4
The jellyfish Nemopilema nomurai was hydrolyzed with papain and a novel dipeptide purified via ultrafiltration, gel filtration chromatography with Sephadex LH-20, and reverse phase chromatography using $C_{18}$ and $C_{12}$ columns. The IR, 1H NMR, 13C NMR, and MS spectrometer analyses showed that the dipeptide comprised tyrosine-isoleucine (Tyr-Ile). The $IC_{50}$ and $K_i$ values were $6.56{\pm}1.12$ and $3.10{\pm}0.28\;{\mu}M$, respectively, indicating competitive inhibition of angiotensin-I-converting enzyme (ACE). As a novel ACE-inhibitory active peptide, Tyr-Ile may have potential for use in antihypertensive therapy.
김현숙,김계남,오도연,신길자,이우형 梨花女子大學校 醫科大學 醫科學硏究所 1983 EMJ (Ewha medical journal) Vol.6 No.4
A case of lead poisoning is presented and recent litures are reviewed. A 47-year old male had been admitted to Ewha Womans University Hospital in March 1983 with chief complaints of abdominal colic & distention, nausea and tingling sensation of lower extremities after ingestion of herb pills(HAE GU SIN). Laboratory examinations are as follows; anemia with hypocromic, microcytic, basophilic stippling of erythrocytes in peripheral blood and bone marrow. Blood level of lead was 34.6mcg/㎗, urine level of lead was 128.4mcg/L, coproporphyrine and △-ALA in 24hours urine were 270.8mcg/L, 19.9㎎/L respectively. After treatment with BAL for 1 day, blood level of lead was 30.4mcg/㎗, urine level of lead was 2988.6mcg/L, coproporphyrine and △-ALA in 24hours urine were increased to 667.2mcg/L, 5.5㎎/L respectively and quantitative analysis of herb pills revealed 10% of containing lead.
전정부와 체부에서의 H. pylori 진단율과 장상피화생
김나영,고영희,임선희,고재중,이계희,오주현,이창균,최신은 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.1
Aims: In this paper we have investigated the detection rate of each H. pylori test in the antrum and in the body for patients with nonulcer dyspepsia (NUD), duodenal ulcer (DU), benign gastric ulcer (BGU), and stomach cancer. In addition, we examined whether or not there is any relationship between the decrease of H. pylori detection rate and intestinal metaplasia in the antrum. Methods: Three different test methods for identifying H. pylori infection-CLOtest, Gram stain, H&E stain-were taken in the antrum and in the body. Results: 1) The detection rates of CLOtest, Gram stain, and H&E stain for NUD group were 88%, 75%, and 64% (mean: 76%) in the antrum, and 89%, 78%, and 67% (mean: 78%) in the body, respectively, and those of DU group were 95%, 95% and 81% (mean: 90%) in the antrum, and 97%, 87% and 64% (mean: 83%) in the body, respectively. Those of BGU group were 86%, 74%, 53% (mean: 71%) and 98%, 82%, 58% (mean: 79%), respectively, and those of stomach cancer group were 80%, 88%, 58% (mean: 75%) in the antrum, and 100%, 96%, 83% (mean: 93%) in the body, respectively. The B/A detection ratio which means the ratio of mean H. pylori detection rate of body to that of antrum was 1.03 in NUD, 0.93 in DU, 1.11 in BGU, and 1.24 in stomach cancer group. 2) The rate of intestinal metaplasia in the antrum was 12% for NUD, and 15% for DU group. Those of BGU and stomach cancer group were 47% and 72%, respectively. 3) The correlation etween B/A detection ratio and intestinal metaplasia in the antrum was good (correlation coefficient(r)=0.93). Conclusions: The result that body is more adequate for H. pylori detection in BGU and stomach cancer patients rather than antrum can be explained by the high rate of intestinal metaplasia in the antrum which is hostile surrounding for H. pylori.
Lee, Nakwon,Kim, Sang-Ha,Kwon, Woocheol,Lee, Myoung Kyu,Yong, Suk Joong,Shin, Kye Chul,Jung, Ye-Ryung,Choi, Yeun Seoung,Choi, Jiwon,Choi, Ji Sun,Lee, Won Yeon The Korean Academy of Tuberculosis and Respiratory 2014 Tuberculosis and Respiratory Diseases Vol.77 No.6
Background: Transbronchial lung biopsy (TBLB) is a valuable diagnostic tool for peripheral pulmonary lesions. The diagnostic yield of TBLB reportedly ranges from 41%-60%. Many studies demonstrated the various factors that influence the yield of TBLB, including size, location, and distance from the carina or pleura. However, no study has evaluated the effects of the bronchoscope diameter. We evaluated whether the bronchoscope diameter affected the diagnostic yield of TBLB. Methods: We reviewed records from 178 patients who underwent TBLB using bronchoscopes of two different diameters (5.7 mm, thick outer diameter, Olympus BF-200; 4.9 mm, thin, BF-260). The fluoroscopic guidance rates, yield of TBLB and flexible bronchoscopy (FB) were compared between the two groups. Additionally, we compared the results of the procedures with respect to diagnosis, distance from the pleura, and size of the lesion. Results: The results of fluoroscopic guidance, TBLB, and FB yield using thin diameter bronchoscope were significantly better than those obtained with a thick diameter bronchoscope (p=0.021, p=0.036, and p=0.010, respectively). Particularly, when the distance from the pleura was ${\leq}10mm$, success rates for fluoroscopic guidance and FB with thin bronchoscope were higher (p=0.013 and p=0.033, respectively), as compared to with thick bronchoscope. Conclusion: A thinner diameter bronchoscope increased the yield of bronchoscopy, and bronchial washing in conjunction with TBLB was useful in the diagnosis of peripheral pulmonary nodules.