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Seo, Hocheol,Kim, Yeonjoo Copernicus GmbH 2019 Geoscientific model development Vol.12 No.1
<P><p><strong>Abstract.</strong> Fire plays an important role in terrestrial ecosystems. The burning of biomass affects carbon and water fluxes and vegetation distribution. To understand the effect of interactive processes of fire and ecological succession on surface carbon and water fluxes, this study employed the Community Land Model version 4.5 to conduct a series of experiments that included and excluded fire and dynamic vegetation processes. Results of the experiments that excluded the vegetation dynamics showed a global increase in net ecosystem production (NEP) in post-fire regions, whereas the inclusion of vegetation dynamics revealed a fire-induced decrease in NEP in some regions, which was depicted when the dominant vegetation type was changed from trees to grass. Carbon emissions from fires are enhanced by reduction in NEP when vegetation dynamics are considered; however, this effect is somewhat mitigated by the increase in NEP when vegetation dynamics are not considered. Fire-induced changes in vegetation modify the soil moisture profile because grasslands are more dominant in post-fire regions. This results in less moisture within the top soil layer than that in unburned regions, even though transpiration is reduced overall. These findings are different from those of previous fire model evaluations that ignored vegetation dynamics and thus highlight the importance of interactive processes between fires and vegetation dynamics in evaluating recent model developments.</p> </P>
Sangho Sohn,Yeonjoo Seo,Yunsik Jeong,Seungwoo Lee,Jeesun Lee,이경주 한국보건의료인국가시험원 2021 보건의료교육평가 Vol.18 No.-
Purpose: In 2015, the South Korean government legislated the Act for the Improvement of Training Conditions and Status of Medical Residents (Medical Resident Act). This study investigated changes in the working and learning environment pre- and post-implementation of the Medical Resident Act in 2017, as well as changes in training conditions by year post-implementation. Methods: An annual cross-sectional voluntary survey was conducted by the Korean Intern Resident Association (KIRA) between 2016 and 2019. The learning and working environment, including extended shift length, rest time, learning goals, and job satisfaction, were compared by institution type, training year, and specialty. Results: Of the 55,727 enrollees in the KIRA, 15,029 trainees took the survey, and the number of survey participants increased year by year (from 2,984 in 2016 to 4,700 in 2019). Overall working hours tended to decrease; however, interns worked the most (114 hours in 2016, 88 hours in 2019; P<0.001). Having 10 hours or more of break time has gradually become more common (P<0.001). Lunch breaks per week decreased from 5 in 2017 to 4 in 2019 (P<0.001). Trainees’ sense of educational deprivation due to physician assistants increased from 17.5% in 2016 to 25.6% in 2018 (P<0.001). Awareness of tasks and program/work achievement goals increased from 29.2% in 2016 to 58.3% in 2018 (P<0.001). Satisfaction with the learning environment increased over time, whereas satisfaction with working conditions varied. Conclusion: The Medical Resident Act has brought promising changes to the training of medical residents in Korea, as well as their satisfaction with the training environment.
기후변화 적응을 위한 우리나라 수문학적 가뭄 위험도 평가
서정호,지혜원,김혜진,김연주,Seo, Jungho,Chi, Haewon,Kim, Heey Jin,Kim, Yeonjoo 한국수자원학회 2022 한국수자원학회논문집 Vol.55 No.6
As natural disasters have been increasing due to climate change, sustainable solutions are in need to alleviate the degree of drought hazard, assess and project the drought influence based on future climate change scenarios. In assessing drought risk, socio-economic factors of the region must be considered along with meteorological factors. This study categorized drought hazard, exposure, and vulnerability as three major components of drought risk according to the Intergovernmental panel on Climate Change (IPCC) risk assessment framework, and selected indices for each component to quantify the drought risk in South Korea according to the mid-size basins. Combinations of climate scenarios (Representative Concentration Pathway; RCP 2.6 and RCP 8.5) and socio-economic scenarios (Shared Socio-economic Pathways; SSP 1, SSP2 and SSP3) for the near future (2030-2050) ant the far future (2080-2099) were utilized in drought risk analysis, and results were compared with the historical data (1986-2005). In general, the drought risks for all scenarios shows large increases as time proceeds to the far furture. In addition, we analyzed the rank of drought hazard, exposure, vulnerability for drought risk, and each of their contribution. The results showed that the drought hazard is the most contributing component to the increase of drought risk in future and each basin shows varying contributing components. Finally, we suggested countermeasures for each basin according to future climate change scenarios, and thus this study provides made the basis for establishing drought management measures.
Collateral effect of the COVID-19 pandemic on emergency department visits in Korea
여인환,김종근,( Byunghyuk Yu ),( Kang-suk Seo ),( Jung-bae Park ),( Yeonjoo Cho ),( Jae Young Choe ),( Changho Kim ),( Yun Jeong Kim ),( Dong Eun Lee ),( In Hwan Yeo ),( Won-kee Lee ) 대한응급의학회 2022 대한응급의학회 학술대회초록집 Vol.2022 No.2
Yu, Namhee,Yong, Seunghui,Kim, Hong Kwan,Choi, Yoon‐,La,Jung, Yeonjoo,Kim, Doyeon,Seo, Jihae,Lee, Ye Eun,Baek, Daehyun,Lee, Jinseon,Lee, Seungjae,Lee, Jong Eun,Kim, Jaesang,Kim, Jhingook,Lee, Sa John Wiley and Sons Inc. 2019 MOLECULAR ONCOLOGY Vol.13 No.6
<P>The roles of miRNAs in lung cancer have not yet been explored systematically at the genome scale despite their important regulatory functions. Here, we report an integrative analysis of miRNA and mRNA sequencing data for matched tumor–normal samples from 109 Korean female patients with non‐small‐cell lung adenocarcinoma (LUAD). We produced miRNA sequencing (miRNA‐Seq) and RNA‐Seq data for 48 patients and RNA‐Seq data for 61 additional patients. Subsequent differential expression analysis with stringent criteria yielded 44 miRNAs and 2322 genes. Integrative gene set analysis of the differentially expressed miRNAs and genes using miRNA–target information revealed several regulatory processes related to the cell cycle that were targeted by tumor suppressor miRNAs (TSmiR). We performed colony formation assays in A549 and NCI‐H460 cell lines to test the tumor‐suppressive activity of downregulated miRNAs in cancer and identified 7 novel TSmiRs (miR‐144‐5p, miR‐218‐1‐3p, miR‐223‐3p, miR‐27a‐5p, miR‐30a‐3p, miR‐30c‐2‐3p, miR‐338‐5p). Two miRNAs, miR‐30a‐3p and miR‐30c‐2‐3p, showed differential survival characteristics in the Tumor Cancer Genome Atlas (TCGA) LUAD patient cohort indicating their prognostic value. Finally, we identified a network cluster of miRNAs and target genes that could be responsible for cell cycle regulation. Our study not only provides a dataset of miRNA as well as mRNA sequencing from the matched tumor–normal samples, but also reports several novel TSmiRs that could potentially be developed into prognostic biomarkers or therapeutic RNA drugs.</P>