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( Man Chin Hua ),( Hsun Chin Chao ),( Tsung Chieh Yao ),( Ming Wei Lai ),( Jing Long Huang ),( The Patch Study Group ) 대한소화기학회 2013 Gut and Liver Vol.7 No.4
Background/Aims: The aim of this study was to investigate whether genetic variations at positions -1082, -819, and 592 in the interleukin (IL)-10 promoter affect IL-10 production in children with irritable bowel syndrome (IBS). Methods: Ninety-four children with IBS and 102 children as healthy controls (HCs) were enrolled. Genomic DNA was extracted, and IL-10 -1082, -819, and -592 polymorphisms were detected by direct sequencing from all participants. Peripheral blood mononuclear cells (PBMCs) from 46 IBS children and 38 HCs were isolated and cultured with and without 5 ng/mL Escherichia coli lipopolysaccharide (LPS). IL-10 levels in the culture supernatants were measured by enzyme-linked immunosorbent assay. Results: There were no significant differences in the distribution of IL-10 -1082, -819, and -592 polymorphisms or in the allele and haplotype frequencies between IBS children and HCs. PBMCs from children with IBS had significantly lower IL-10 levels after LPS stimulation than PBMCs from HCs (p=0.011); however, LPS-induced IL-10 levels in PBMCs with different genotypes of -819 and 592 polymorphisms were not significantly different between IBS patients and HCs. Conclusions: Although significantly lower LPS-induced IL-10 production by PBMCs was noted, it is unlikely that IL-10 production was fully genetically determined in our IBS children. ClinicalTrials.gov identifier: NCT01131442. (Gut Liver 2013; 7:430-436)
An Orthogonal Study of Industrial Scale Colour Fading Process of Cotton Fabric
Yao-hui Liu,Chester Kin-Man To,Hiu-yan Cheung,Chi-wai Kan,Hong Chua 한국섬유공학회 2019 Fibers and polymers Vol.20 No.3
Colour fading is now a popular process used for imparting a vintage look to textile and fashion products, whichenhances market value because of the current fashion trends. This study examined a non-aqueous colour fading process with the use of oxygen plasma-induced ozone treatment. An industrial scale machine and commercially available red sulpur-dyed cotton fabric (with 0.5 %, 1.5 % and 2.5 % colour depths) were used in this study. Since the colour fading process factors are inter-related to each other, a specific experiment approach, i.e. orthogonal method, was used for obtaining the optimum conditions in an industrial scale colour fading process. Three process factors used in the industrial scale colour fading process, i.e. (i) oxygen gas concentration (%); (ii) amount of water in fabric (%); and (iii) treatment time (minutes), would be studied in this paper. Through the orthogonal method, the optimum conditions for colour fading of the three colour depths of cotton fabric dyed by red sulphur dye were determined and their optimum conditions were same. The optimum conditions of the colour fading of the three colour depths were: (i) 70 % oxygen gas concentration; (ii) 35 % amount of water in fabric; and (iii) 30 minutes treatment time. Although colour fading conditions are the same, the order of importance of these process factors was different. Unlike the conventional colour fading process, oxygen plasma-induced ozone colour fading treatment can achieve uniform and even colour fading effect in the cotton fabric effectively.
TiO2ecarbon nanotube composites for visible photocatalysts - Influence of TiO2 crystal structure
Mu Yao Guo,Fangzhou Liu,Yu Hang Leung,Alan Man Ching Ng,Aleksandra B. Djurišić,Wai Kin Chan 한국물리학회 2013 Current Applied Physics Vol.13 No.7
We investigated the influence of the crystal structure of TiO2 and the use of different TiO2 precursors on the properties and photocatalytic activity of carbon nanotube (CNTs)etitania composites. We found that the crystal structure and properties of starting TiO2 nanomaterial significantly affected the effect of CNTs incorporation on the photocatalytic activity under simulated solar and visible light illumination (simulated solar illumination with UV-blocking filter). In case of significant photocatalytic activity under visible light illumination (anatase TiO2), likely due to the presence of native defects, composites exhibited lower activity under visible illumination only, but higher activity under simulated solar illumination. The opposite trends were observed for P25 (anatase þ rutile) and rutile TiO2, where incorporation of CNTs resulted in a significant increase of photocatalytic activity under visible illumination. Thus, control over crystal structure and native defects is essential for the development of efficient visible light activated photocatalysts.
SOME DESIGN CONSIDERATIONS IN NETWORK DATABASE DESIGN
Sheng, Yao Wan,Hua, Xu Shu,Li, Wang Xiao,Hua, Zhao Man 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1
Computer Network has been widely used. Network databases design is a important technical issues. This paper presents some technical considerations in destgning a network databases. These considerations are: ratio analysis, design decision tree, syneronization and network data management.
Hang Yu,Man Ding,Qian Cao,Rumeng Zhou,Jiajia Yao,Rong Fu,Yue Liu,Zheman Xiao,Zuneng Lu 대한신경과학회 2023 Journal of Clinical Neurology Vol.19 No.6
Background and Purpose We aimed to determine the clinical features of Miller Fisher syndrome (MFS) in southern China and compare them with those presenting in other countries. Methods We collected the medical records of patients diagnosed with MFS during 2013–2016. We analyzed the age, sex, onset season, precursor events, clinical symptoms and signs, findings of nerve conduction studies (NCS), cerebrospinal fluid (CSF), therapeutic remedies, nadir time, and length of hospital stay of patients with MFS in southern China. We concurrently compared the differences between urban and rural areas and between patients with incomplete ophthalmoplegia (IO) and complete ophthalmoplegia (CO). Results The study enrolled 72 patients: 36 from rural areas and 36 from urban areas, and 50 males and 22 females. The mean age at onset was 47.72 years, and 30 (41.7%) and 21 (29.2%) patients developed MFS in spring and winter, respectively. The typical triad of ophthalmoplegia, ataxia, and areflexia was observed in 50 (69.4%) patients. A history of upper respiratory tract infection 1 week before onset was found in 52.8% of the patients, while 5.6% experienced gastrointestinal infections and 48 (73.8%) exhibited albuminocytological dissociation in the CSF study. Only 26 (36.1%) patients presented abnormalities in NCS. Moreover, restricted outward eyeball movement presented in 83.5% of the patients with classic MFS and acute ophthalmoplegia, and bilateral symmetrical ophthalmoplegia presented in 64.2%. With the exception of the higher proportion of NCS abnormalities in urban areas (47.2% vs. 25.0%), urban and rural differences were insignificant regarding sex ratio, age at onset, high-incidence season, precursor events, disease characteristics, and albuminocytological dissociation in the CSF. Furthermore, patients with CO were older than those with IO (64.53±7.69 vs. 43.19±14.40 years [mean±standard deviation], p<0.001). Conclusions The patients with MFS were mostly male and middle-aged, and most presented in winter and (especially) spring. More than half of the patients had clear precursor events, most of which were classic MFS with the typical triad. More than 70% of the patients presented albuminocytological dissociation in the CSF. NCS abnormalities were uncommon in MFS. The age at onset was lower in patients with IO than in patients with CO; bilateral symmetrical extraocular muscle paralysis was the most common symptom, and the external rectus was the most frequently involved muscle.
Shan-Jing Yao,Yi-Xin Guan,Hai-Xue Pan,Yong-Gui Gao,Man-Gi Cho 한국생물공학회 2005 Biotechnology and Bioprocess Engineering Vol.10 No.2
A size exclusion chromatography (SEC) process, in the presence of denaturant in the refolding buffer was developed to refold recombinant human interferon- (rhIFN-) at a high concentration. The rhIFN- was overexpressed in E. coli, resulting in the formation of inactive inclusion bodies (IBs). The IBs were first solubilized in 8 M urea as the denaturant, and then the refolding process performed by decreasing the urea concentration on the SEC column to suppress protein aggregation. The effects of the urea concentration, protein loading mode and column height during the refolding step were investigated. The combination of the buffer-exchange effect of SEC and a moderate urea concentration in the refolding buffer resulted in an efficient route for producing correctly folded rhIFN-, with protein recovery of 67.1% and specific activity up to 1.2 107 IU/mg.
Shanshan Fang,Yawen Zhou,Man Zhou,ZHONGYU LI,SONG XU,Chao Yao 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.58 No.-
ZnFe2O4/CdS composites were successfully prepared by a facile process. The obtained samples have beencharacterized by X-ray diffraction (XRD), scanning electron microscopy (FE-SEM), transmission electronmicroscopy (TEM), diffuse reflection spectroscopy (DRS), Raman spectroscopy and photoluminescence(PL). Under visible light irradiation, ZnFe2O4/CdS composite shows higher photocatalytic activity in the Cr(VI) reduction, relative to the pure CdS and ZnFe2O4. The enhanced photocatalytic performance wasascribed to the intimate contact interfaces and matching band potentials between CdS and ZnFe2O4, andcan be related to the efficient transfer and separation of the electron-hole pairs. It was found that themodification of ZnFe2O4 did not affect the morphology of CdS. The result of PL test indicated a lowerintensity, and effective separation of photogenerated electron-hole pairs. In addition, the ZnFe2O4/CdScomposites showed more intense optical absorption than that of pure CdS and ZnFe2O4. Through theanalysis of experiment results, a reasonable photocatalytic mechanism over ZnFe2O4/CdS photocatalystswas also proposed.