Steel scale-CaO composite catalyst for coke combustion and in-situ NO and SO2 removal

Li Zhang,Jingchong Yan,Zhiping Lei,Xianzhong Cao,Tiejun Chun,Zhanku Li,Hengfu Shui,Shibiao Ren,Zhicai Wang,Ying Kong 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.110 No.-

The performance of the steel scale (SS)-CaO composite on the combustion of coke nuts and in-situ reductionof SO2 and NO emission was investigated. Combustion experiments show that SS-CaO compositeaccelerates coke combustion and reduces SO2 and NO emissions concurrently. X-ray diffraction (XRD),scanning electron microscopy (SEM), and electron spin resonance (ESR) were used to investigate thecatalysis mechanism. Results show that SS and CaO have synergistic effect in in-situ denitration. Theincrease of SS and CaO fraction in the composites improve the denitration and sulfur fixation performance,respectively. The denitration activity is mainly attributed to the Fe2O3 in SS and Ca2Fe2O5 formedduring combustion. The desulfurization is due to the sulfur fixation with CaO. The increasing fraction ofCaO in the composites leads to the agglomeration of ash particles. 2%CaO is confirmed as the optimumaddition for catalytic combustion and emission reduction. This work sheds light on the cheap and effectivecatalysts that are potentially useful for iron ore sintering.

Interactive Olfaction and Future Opportunities

CAO YAN YAN 창의융합 디자인연구소 2021 창의융합연구 Vol.1 No.2

Clinical Observations on Associations Between the UGT1A1 Genotype and Severe Toxicity of Irinotecan

Lu, Yan-Yan,Huang, Xin-En,Wu, Xue-Yan,Cao, Jie,Liu, Jin,Wang, Lin,Xiang, Jin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

Background: Severe toxicity is commonly observed in cancer patients receiving irinotecan (CPT-11) UDPglucuronosyltransferase1A1 (UGT1A1) catalyzes the glucuronidation of the active metabolite SN-38 but the relationship between UGT1A1 and severe toxicity remains unclear. Our study aimed to assess this point to guide clinical use of CPT-11. Materials and Methods: 89 cancer patients with advanced disease received CPT-11-based chemotherapy for at least two cycles. Toxicity, including GI and hematologic toxicity was recorded in detail and UGT1A1 variants were genotyped. Regression analysis was used to analyse relationships between these variables and tumor response. Results: The prevalence of grade III-IV diarrhea was 10.1%, this being more common in patients with the TA 6/7 genotype (5 of 22 patients, 22.7%) (p<0.05). The prevalence of grade III-IV neutropenia was 13.4%and also highest in patients with the TA 6/7 genotype (4 of 22 patients; 18.2%) but without significance (p>0.05). The retreatment total bilirubin levels were significantly higher in TA6/7 patients (mean, $12.75{\mu}mol/L$) with compared to TA6/6 (mean, $9.92{\mu}mol/L$) with p<0.05. Conclusions: Our study support the conclusion that patients with a $UGT1A1^*28$ allele (s) will suffer an increased risk of severe irinotecan-induced diarrhea, whether with mid-or low-dosage. However, the $UGT1A1^*28$ allele (s) did not increase severe neutropenia. Higher serum total bilirubin is an indication that patients UGT1A1 genotype is not wild-type, with significance for clinic usage of CPT-11.

Phase II Study on Javanica Oil Emulsion Injection (Yadanzi^®) Combined with Chemotherapy in Treating Patients with Advanced Lung Adenocarcinoma

Lu, Yan-Yan,Huang, Xin-En,Cao, Jie,Xu, Xia,Wu, Xue-Yan,Liu, Jin,Xiang, Jin,Xu, Lin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

Purpose: To investigate the efficacy and safety of Javanica oil emulsion injection (Yadanzi$^{(R)}$) combined with pemetrexed and platinum (PP) for treating patients with advanced lung cancer. Patients and Methods: From June 2011 to June 2013, we recruited 58 patients with advanced lung cancer, and divided them into two groups. Twenty eight patients received Yadanzi$^{(R)}$ (from ZheJiang Jiuxu Pharmaceutical Co., Ltd.) together with PP chemotherapy (combined group), while the others were given only PP chemotherapy (control group). After two cycles of treatment, efficacy and safety of treatment were evaluated. Results: The overall respnse rate [(CR+PR+SD)/(CR+PR+SD+PD)] of the combined group was higher than that of control group (89.7% vs. 86.2%, p>0.05). Regarding rate of life improvement, it was 82.8% in combined group, and 51.7% in the control group (p<0.05). In terms of side effects, leukopenia in combined group was less frequent than that in control group (p<0.05). More patients in the control group were found to suffer liver toxicity. Conclusions: Javanica oil emulsion injection combined with chemotherapy could be considered as a safe and effective regimen in treating patients with advanced lung adenocarcinoma. It can improve the quality of life and reduce the possibility of leukopenia. Further clinical trials with a large sample size should be conducted to confirm whether addition of Yadanzi$^{(R)}$ to chemotherapy could increase the response rate, reduce toxicity, enhance tolerability and improve quality of life for patients with advanced lung cancer.

Potential Predictors of Sensitivity to Pemetrexed as First-line Chemotherapy for Patients with Advanced Non-Squamous NSCLCs

Lu, Yan-Yan,Huang, Xin-En,Xu, Lin,Liu, De-Gan,Cao, Jie,Wu, Xue-Yan,Liu, Jin,Xiang, Jin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Background: Pemetrexed (PEM) is effective in first-line treatment for patients with non-squamous non-small cell lung cancer (NSCLC). However there are currently no definitive determinants to certify which patients could benefit from PEM. To improve the efficacy of PEM combined with platinum as first-line therapy for advanced non-squamous NSCLC, we conducted this retrospective study to detect potential determinants of this regimen. Methods: We recruited 109 patients with advanced non-squamous NSCLC who received PEM with a platinum as first-line therapy from June 2006 to February 2013 in Jiangsu Cancer Hospital. Multiple variables (age, sex, smoking, degree of cell differentiation, hemoglobin, platinum drugs combined, positions of metastasis) were selected. Logistic regression analysis was used to analyse relationships between these variables and tumor response. Result: In univariate analysis, we found that age and platinum significantly influenced the results of PEM therapy (P<0.05). In multivariable analysis, no factors were independently significant. Conclusion: Our analysis did not suggest that the age, sex, metastasis of liver or other organs, hemoglobin, smoking history and pathological differentiation are associated with the response of PEM. We should conduct further analyses with larger sample size to reconfirm this issue.

Experimental-based optimization of polymer injection molding process parameters using anfis-ga method

Yanli Cao,Xi-ying Fan,Yong-huan Guo,Xin Liu,Chunxiao Li,Lulu Li 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.3

Compared with ordinary injection-molded parts, the slender, cantilevered, and thin-walled plastic parts are harsh on the injection molding process conditions. For complexity and particularity, it is difficult to form such parts. It is also more likely to cause excessive warpage deformation, affecting the molding quality and performance. The automobile audio shell is a typical slender, cantilevered, thin-walled plastic part. When the mold structure and material are determined, optimizing its injection molding process is the most economical and effective method to manufacture the products with the optimum properties. In order to minimize the warpage deformation, the adaptive network based fuzzy inference system (ANFIS) and genetic algorithm (GA) were adopted to optimize the injection molding process parameters. In particular, considering the high-dimensional nonlinear relationship between the process parameters and the warpage, the ANFIS is constructed as the prediction model of the warpage. Then, the GA is used to globally optimize the prediction model to determine the optimal process parameters. The results show that the optimization method based on ANFIS-GA has a good performance. The warpage is reduced to 0.0925 mm while reduced by 88.25 %. The optimal injection molding process parameters are used for simulation and manufacture, verifying the effectiveness and reliability of the optimization method.

ON SPLIT LEIBNIZ TRIPLE SYSTEMS

Cao, Yan,Chen, Liangyun Korean Mathematical Society 2017 대한수학회지 Vol.54 No.4

In order to study the structure of arbitrary split Leibniz triple systems, we introduce the class of split Leibniz triple systems as the natural extension of the class of split Lie triple systems and split Leibniz algebras. By developing techniques of connections of roots for this kind of triple systems, we show that any of such Leibniz triple systems T with a symmetric root system is of the form $T=U+{\sum}_{[j]{\in}{\Lambda}^1/{\sim}}I_{[j]}$ with U a subspace of $T_0$ and any $I_{[j]}$ a well described ideal of T, satisfying $\{I_{[j]},T,I_{[k]}\}=\{I_{[j]},I_{[k]},T\}=\{T,I_{[j]},I_{[k]}\}=0 \text{ if }[j]{\neq}[k]$.

Optimization algorithms for composite beam as smart active control of structures using genetic algorithms

Yan Cao,Yousef Zandi,Morteza Gholizadeh,Leijie Fu,Jiang Du,Xueming Qian,Zhijie Wang,Angel Roco-Videla,Abdellatif Selmi,Alibek Issakhov 국제구조공학회 2021 Smart Structures and Systems, An International Jou Vol.27 No.6

The principles of productive active and semi-active civil and infrastructure engineering structural control date back 40 years and significant progress has been recorded in those four decades. Smart structures typically have some control systems that enable them to deal with perturbations. The active vibration management techniques have been applied numerically and experimentally in order to reduce the vibrational levels of lightweight economic composite structures. Smart composite beams and plates have been produced and tested with surface-based piezoelectric sensors and actuators. It has been found that an effective model of smart composite plates can predict the dynamic characteristics. Utilizing Genetic Algorithm (GA) was designed and implemented. Two regression model as root mean square (RMSE) and determination coefficient (R²) were used. The first and second bending modes are operated effectively by a beam, and simultaneous vibration levels are significantly reduced for the conductive plates by the simultaneous operation of the bending and twisting modes. Vibration management is realized by using efficient control. GA could show better performance for managing linear feedback laws under given assumptions.

Comparison of Efficacy and Toxicity of First Line Chemotherapy with or without Epirubicin for Patients with Advanced Stage Soft Tissue Sarcoma

Cao, Jie,Huang, Xin-En,Liu, Jin,Wu, Xue-Yan,Lu, Yan-Yan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

Purpose: To compare the safety and efficacy of first-line chemotherapy regimen with or without doxorubicin in treating patients with advanced soft tissue sarcoma (STS). Patients and Methods: We retrospectively analyzed a cohort of 56 patients histologically confirmed with STS who were treated at Jiangsu Cancer Hospital and Research Institute from July 2011 to June 2012.The basic element of first line chemotherapy contained epirubicin in group B and lacked epirubicin in group A. Response was assessed using RECIST criteria. The Kaplan-Meier method was used to estimate progress free survival (PFS). Results: According to RECIST criteria, patients in group treated by chemotherapy without epirubicin, the objective response (OR) ratio was 6.5 % (CR0%+PR6.5%). Disease control rate (DCR=CR+PR+SD) was 25.8% with a median follow-up of 14.6 months, including 2 patients achieving a partial response (PR 6.5%) and a stable response (SD 19.4%) in 6. In group B with epirubicin based regimens, no patient had complete response, PR (28 %) was observed in 7 and SD (24 %) in 6. DCR was observed in 13 patients (52%). By Fisher's exact test, the DCR difference between the two groups was statistically significant (p=0.046). In group A, median PFS was 3.0 months (95%CI:2.1-3.8), compared with 4.0 months (95% CI:3.03-4.97) in group B (p=0.0397 by log-rank test). Epirubicin based chemotherapy and ECOG performance status 0-1 were identified as favorable factors for progression in our cohort of patients. Differences of nonhematologic and hematologic toxicities were not statistically significant between the two groups, and the addition of epirobicin was not associated with cardiac toxicity (p=0.446). Conclusion: Our study demonstrates that epirubicin-based chemotherapy is effective and well tolerated, and is superior to chemotherapy without epirubicin regarding efficacy. Therefore it is recommended that epirubicin-based chemotherapy should be considered as first line for patients with advanced STS.

The Impact of Line Resistance on Load Sharing and An Improved Droop Control of DC Microgrid

CAO Wei,YANG Daopei,CAO Jialin,WANG Yongzhi,YAN Yuxing 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6

This paper proposes an effective DC voltage and power sharing droop control structure for DC microgrid based on public bus voltage feedback signal. Firstly, the impact of the line resistance on power sharing among droop controlled distributed generators is analyzed and the reason why the line resistance cannot be ignored is presented. Then, an improved droop control is proposed. The simulation test based on MATLAB/Simulink was implemented to demonstrate the proposed approach.