Effect of reservoir properties on the heat extraction performance in multi-well production EGS

Liu Songze,Wei Jianguang,Liu Hongliang,Liu Xuemei,Yan Bingxu 한국자원공학회 2021 Geosystem engineering Vol.24 No.4

A multi-well production enhanced geothermal system (EGS) with discrete fracture network is designed for heat extraction in this study. A thermal-hydraulic numerical simulation model is established, and the effect of reservoir properties on heat extraction is investigated. The results show that the growth rate of heat extraction efficiency will decrease as the mining time increases. The initial reservoir temperature has a positive correlation with average production temperature which provides a broad space for the use of extracted thermal energy. The variation of initial reservoir pressure has little effect on the heat extraction performance. A higher matrix permeability leads to a higher average production temperature and heat extraction ratio which prompts more working fluid flow into the matrix, the heat transfer process is enhanced. Under the conditions of this study, the preferred initial reservoir temperature is 493.15 K, the matrix permeability is 10−14m2.

Efficacy and safety of herbal medicine (Binafuxi granules) for the common cold with fever: A multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial

Liu Xuemei,Min Jie,She Bin,Chen Yang,Li Jun,Huang Lei,Chen Ju,Luo Ai,Mei Yang,Li Ting,Wu Yanqing,Chen Daohong,Hongli Zhong,Liu Wei,Mao Bing,Jiang Hongli 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3

Background: Binafuxi granules are a traditional Uighur medicine (TUM) for treating the common cold with fever. However, high-quality clinical studies supporting its efficacy and safety are lacking. Methods: In this multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial, patients with common cold and fever were randomly assigned to a high-dose group, low-dose group, and placebo group in a 1:1:1 ratio. Outcomes were time to fever relief, time to fever clearance, proportion of afebrile patients, time to symptom disappearance, rate of symptom disappearance, effective rate, emergency drug usage and safety assessment. Results: A total of 235 patients were recruited. Of these, 234 were included in the full analysis set (FAS), and 217 were included in the per-protocol set (PPS). In the FAS analysis, the median time to fever relief was 6.00 h, 5.54 h and 10.65 h (P = 0.31) in the high-dose group, low-dose group and placebo group, respectively. The median time to fever clearance was 18.29 h, 20.08 h and 25.00 h (P = 0.0018), respectively, and the proportion of afebrile patients was 92.4%, 89.7% and 71.4% (P = 0.0002), respectively. There was a significant difference in the disappearance time and disappearance rate of all symptoms and of individual symptoms. No serious adverse events were found. Conclusions: Binafuxi granules can dose-dependently shorten the fever course and improve clinical symptoms in patients suffering from the common cold with fever.

Angle-stable top-emitting white organic light-emitting devices employing a down-conversion layer

Shihao Liu,Xuemei Wen,Wenbo Liu,Wei Zhang,Jing-Yuan Wang,Wenfa Xie,Letian Zhang 한국물리학회 2014 Current Applied Physics Vol.14 No.11

Angle-stable white top-emitting organic light-emitting devices (WTEOLEDs) by the combination of a blue TEOLED with a down-conversion (DC) layer are demonstrated. The DC layer is composed of red fluorescent dye doped in a host of tris (8-hydroxy-quinolinato) aluminum. The TEWOLED shows a CIE coordinates of (0.240, 0.332) and a maximum current efficiency of 3.95 cd/A. Furthermore, theWTEOLED shows excellently angle-stable characteristic, the CIE coordinates at 20 mA/cm2 only shift by (0.023, 0.007) from 0 to 60. It can be attributed to the angle-stable blue TEOLED based on the Ag/Ge/Ag transparent cathode.

Candidate Genes with Ovulation by Differential Display PCR in Small Tail Han Sheep

Liu, Shufang,Li, Hongbin,Song, Xuemei,Wang, Aihua,Wei, Caihong,Du, Lixin Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.9

To find the candidate genes concerned with ovulation rate of sheep, Differential Display Reverse Transcription Polymerase Chain Reaction was employed to find the differently expressed cDNA controlling ovulation in the Small Tail Han sheep of polyembryony and in Tan sheep of single birth. Twenty-four primer pairs of three anchored primers and eight arbitrary primers were assembled to amplify the specialized bands from these sheep. Positive cross tests were applied to optimize the ascertainable PCR conditions in which different special bands can be identified by silver strain in one PCR tube. After eliminating the false positive PCR products by Northern hybridization, 24 differential display bands were acquired from the ovary in the Small Tail Han sheep. These EST bands were sequenced and 18 different ESTs were found in which five ESTs had several copies and 13 ESTs had only one copy. Comparing these ESTs with homologous sequences by BLAST in the GenBank, there were six ESTs with known open reading frame (ORF) and function, three ESTs with known ORF and no function, and 9 ESTs without homologous sequence. These ESTs partly represent several genes such as NOS2, tensin, TCRA, CDKN1A, ESR1 and ACTB which express especially in Small Tail Han sheep.

Core–Shell-Structured Monodisperse Copolymer/Silica Particle Suspension and Its Electrorheological Response

Liu, Ying Dan,Quan, Xuemei,Hwang, Bora,Kwon, Yong Ku,Choi, Hyoung Jin American Chemical Society 2014 Langmuir Vol.30 No.7

<P>Monodisperse core–shell-structured poly(styrene-<I>co</I>-butyl acrylate-<I>co</I>-[2-(methacryloxy)ethyl] trimethylammonium chloride)/silica (PSBM/SiO<SUB>2</SUB>) nanoparticles were applied as new electrorheological (ER) materials in which the particles were dispersed in an insulating oil. These nanoparticles were prepared by the consecutive precipitation of cetyltrimethylammonium bromide and negatively charged tetraethylorthosilicate onto the cationic surfaces of PSBM colloidal particles. The successful deposition of the shell phase of the particles and their morphology was examined by transmission and scanning electron microscopy. Their ER properties were studied with a rotational rheometer under different shear modes: controlled shear rate, steady shear under constant shear rate, and creep test. The silica shell allowed the PSBM/SiO<SUB>2</SUB> particles to exhibit typical ER performance under an applied electric field. The dielectric spectra of the PSBM/SiO<SUB>2</SUB>-based ER fluid were also recorded using an LCR meter, which was correlated to the ER performance of the ER fluid.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/langd5/2014/langd5.2014.30.issue-7/la4050072/production/images/medium/la-2013-050072_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/la4050072'>ACS Electronic Supporting Info</A></P>

Molybdenum Dioxide-Anchored Graphene Foam as a Negative Electrode Material for Supercapacitors

Xuemei Mu,Xiaozhi Liu,Ke Zhang,Jian Li,Jinyuan Zhou,ER-QING XIE,Zhenxing Zhang 대한금속·재료학회 2016 ELECTRONIC MATERIALS LETTERS Vol.12 No.2

Molybdenum dioxide nanoparticles of diameter 100 nm were anchoreduniformly to a three-dimensional (3D) graphene foam using an ultrasonicationassisteddeposition method. X-ray diffraction and Raman spectroscopyindicated that the molybdenum dioxide nanoparticles had a monoclinic crystalstructure. The 3D graphene/MoO2 nanoparticle composite showed excellentpseudocapacitive ability as its specific capacitance reached 404 F g−1 at a scanrate of 2 mV s−1 in the negative potential range, −1.0 to −0.2 V, in a neutralsolution. Overall, the 3D graphene/MoO2 nanoparticle composite has greatpotential as an anode material for the next generation of high-performancesupercapacitors.

Knockout of Myostatin by Zinc-finger Nuclease in Sheep Fibroblasts and Embryos

Zhang, Xuemei,Wang, Liqin,Wu, Yangsheng,Li, Wenrong,An, Jing,Zhang, Fuchun,Liu, Mingjun Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.10

Myostatin (MSTN) can negatively regulate the growth and development of skeletal muscle, and natural mutations can cause "double-muscling" trait in animals. In order to block the inhibiting effect of MSTN on muscle growth, we transferred zinc-finger nucleases (ZFN) which targeted sheep MSTN gene into cultured fibroblasts. Gene targeted colonies were isolated from transfected fibroblasts by serial dilution culture and screened by sequencing. Two colonies were identified with mono-allele mutation and one colony with bi-allelic deletion. Further, we introduced the MSTN-ZFN mRNA into sheep embryos by microinjection. Thirteen of thirty-seven parthenogenetic embryos were targeted by ZFN, with the efficiency of 35%. Our work established the technical foundation for generation of MSTN gene editing sheep by somatic cloning and microinjection ZFN into embryos.

Optical Encryption Scheme with Multiple Users Based on Computational Ghost Imaging and Orthogonal Modulation

Sheng Yuan,Xuemei Liu,Xin Zhou,Zhongyang Li 한국광학회 2016 Current Optics and Photonics Vol.20 No.4

For the application of multiusers, the arrangement and distribution of the keys is a much concerningproblem in a cryptosystem. In this paper, we propose an optical encryption scheme with multiple usersbased on computational ghost imaging (CGI) and orthogonal modulation. The CGI encrypts the secret imageinto an intensity vector rather than a complex-valued matrix. This will bring convenience for post-processingand transmission of the ciphertext. The orthogonal vectors are taken as the address codes to distinguishusers and avoid cross-talk. Only the decryption key and the address code owned by an authorized userare matched, the secret image belonging to him/her could be extracted from the ciphertext. Therefore, thereare two security levels in the encryption scheme. The feasibility and property are verified by numericalsimulations.

Simple denoising method for novel speckle-shifting ghost imaging with connected-region labeling

Sheng Yuan,Xuemei Liu,Pibin Bing 한국광학회 2019 Current Optics and Photonics Vol.3 No.3

A novel speckle-shifting ghost imaging (SSGI) technique is proposed in this paper. This method can effectively extract the edge of an unknown object without achieving its clear ghost image beforehand. However, owing to the imaging mechanism of SSGI, the imaging result generally contains serious noise. To solve the problem, we further propose a simple and effective method to remove noise from the speckle-shifting ghost image with a connected-region labeling (CRL) algorithm. In this method, two ghost images of an object are first generated according to SSGI. A threshold and the CRL are then used to remove noise from the imaging results in turn. This method can retrieve a high-quality image of an object with fewer measurements. Numerical simulations are carried out to verify the feasibility and effectiveness.

Assimilating AOD retrievals from GOCI and VIIRS to forecast surface PM_2.5 episodes over Eastern China

Pang, Jiongming,Liu, Zhiquan,Wang, Xuemei,Bresch, Jamie,Ban, Junmei,Chen, Dan,Kim, Jhoon Elsevier 2018 Atmospheric environment Vol.179 No.-

<P><B>Abstract</B></P> <P>In this study, Geostationary Ocean Color Imager (GOCI) AOD and Visible Infrared Imaging Radiometer Suite (VIIRS) AOD data were assimilated to forecast surface PM<SUB>2.5</SUB> concentrations over Eastern China, by using the three–dimensional variational (3DAVR) data assimilation (DA) system, to compare DA impacts by assimilating AOD retrievals from these two types of satellites. Three experiments were conducted, including a CONTROL without the AOD assimilation, and GOCIDA and VIIRSDA with the assimilation of AOD retrievals from GOCI and VIIRS, respectively. By utilizing the Weather Research and Forecasting with Chemistry (WRF/Chem) model, 48-h forecasts were initialized at each 06 UTC from 19 November to 06 December 2013. These forecasts were evaluated with 248 ground-based measurements from the air quality monitoring network across 67 China cities. The results show that overall the CONTROL underestimated surface PM<SUB>2.5</SUB> concentrations, especially over Jing–Jin–Ji (JJJ) region and Yangtze River Delta (YRD) region. Both the GOCIDA and VIIRSDA produced higher surface PM<SUB>2.5</SUB> concentrations mainly over Eastern China, which fits well with the PM<SUB>2.5</SUB> measurements at these eastern sites, with more than 8% error reductions (ER). Moreover, compared to CONTROL, GOCIDA reduced 14.0% and 6.4% error on JJJ region and YRD region, respectively, while VIIRSDA reduced respectively 2.0% and 13.4% error over the corresponding areas. During the heavy polluted period, VIIRSDA improved all sites within YRD region, and GOCIDA enhanced 84% sites. Meanwhile, GOCIDA improved 84% sites on JJJ region, while VIIRSDA did not affect that region. These geographic distinctions might result from spatial dissimilarity between GOCI AOD and VIIRS AOD at time intervals. Moreover, the larger increment produced by AOD DA under stable meteorological conditions could lead to a longer duration (e.g., 1–2 days, > 2 days) of AOD DA impacts. Even though with AOD DA, surface PM<SUB>2.5</SUB> concentrations were still underestimated clearly over heavy polluted periods. And 3% sites performed worse, where low PM<SUB>2.5</SUB> values were observed and CONTROL performed well. With this study, the results indicate that AOD DA can partially improve the accuracy of PM<SUB>2.5</SUB> forecasts. And the obvious geographic differences on forecasts emphasize the potential and importance of combining AOD retrievals from GOCI and VIIRS into data assimilation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> AOD retrievals from two types of satellites were assimilated solely. </LI> <LI> Assimilating different AOD produced prominent geographic differences on forecast. </LI> <LI> Larger increment under stable meteorological conditions lead to a longer duration. </LI> <LI> The results emphasize the potential of combining different AOD retrievals. </LI> </UL> </P>