Peptide-based biosensor for selective detection of bisphenol A

Xue, Xue Sungkyunkwan university 2017 국내석사

Evaluation for Anti-inflammatory Effects of Saururus chinensis

Xue Meng Gachon University Graduate School 2014 국내석사

Heme oxygenase-1 (HO-1) is the rate-limiting microsomal enzyme in heme degradation, which acts as an anti-inflammatory and anti-oxidative potent therapy, and it could be induced by various compounds extracted from the natural plants in macrophages. In this study, it was screened 108 medicinal plants which are frequently used in Korea and China to investigate anti-inflammatory herbal medicinal resources. Also, it was reported that HO-1 protein was expressed by subfraction4 (F.4) that was extracted from the n-hexane fraction of the aerial parts of Saururus chinensis, as known as a kind of anti-inflammatory plant, in RAW264.7 cells in a time- and concentration-dependent manner. Up-regulation of HO-1 by F.4-induced might be regulation of mitogen-activated protein kinases (MAPKs) and phosphatidylinositol 3-kinase (PI3K) /Akt signaling pathways, dependent on the induction of phosphorylated p38 and Akt by F.4. Moreover, the signaling pathway involved F.4-mediated HO-1 induction included p65, a subunit of nuclear factor kappa B (NF-κB), dependent on the F.4-induced p65 expression and pyrrolidine dithiocarbamate (PDTC)-reduced HO-1 expression. F.4-induced HO-1 suppressed the pro-inflammatory enzyme inducible nitric oxide synthase (iNOS), nitric oxide (NO) production and cytokine tumor necrosis factor alpha (TNF-α) but not cyclooxygenase-2 (COX-2) by down-regulating signal transducers and activators of transcription protein 1 (STAT1) activity in LPS-stimulated RAW264.7 cells. Finally, it is suggested that Saururus chinensis can be used as anti-inflammatory resources and it is needed to further study to investigate its major components which act anti-inflammatory and anti-oxidative effects.

The Ethanol extracts of Saussurea lappa induced apoptosis and autophagy in prostate cancer cells

Xue Tian Gachon University 2017 국내석사

Saussurea lappa (SL) have been used as traditional herbal medicine for various disease, such as asthma, inflammatory disease, and ulcers. Extracts of Saussurea lappa have been shown in vitro to cause apoptosis in several types of cancer cells. To demonstrate the mechanisms by which the ethanol extract of Saussurea lappa (SLE) exerts a protective effect against prostate cancer, I evaluated the induction of apoptosis and autophagy by SLE in prostate cancer cells (LNCaP) cells. And we investigated whether SLE-induced autophagy exert pro-survival or pro-apoptotic effect in prostate cancer cell, LNCaP cells. Following optimization of the extract, viability of treated LNCaP cells was determined through the MTT assay using various concentrations of SLE (6.3-100 μg/mL). Cell apoptosis was evaluated using the Tali assay. The expression of apoptosis-related mRNA and proteins was analyzed by quantitative real-time RT-PCR and western blotting. Viability of LNCaP cells was found to be significantly reduced following SLE treatment for 24 h. I also found that SLE treatment increased the expression of Bax, tBid, cleaved caspase 3/8/9, cleaved PARP and FADD proteins while suppressed the expression of Bid and Bcl-2 in LNCaP cells, indicating the induction of apoptosis. PI3K/AKT/mTOR pathway-related proteins and autophagy-related proteins were evaluated by western blot assay. SLE was found to suppress phosphorylation and activation of AKT, AR, PSA, and PTEN, thus downregulating proteins related to cell proliferation in LNCaP cells. SLE exposure also resulted in stimulation of autophagy, as determined from the increase in levels of LC3I, LC3II and Beclin-1 proteins, and suppression of phosphorylation of mTOR. Finally, the inhibition of autophagy by exposure to 3-methyladenine lead to an increasing the apoptosis in LNCaP cell by SLE treatment was verified. The concurrent treatment of LNCaP cells with 3-methyladenine and SLE decreased the expression of anti-apoptotic protein Bcl-2 and increased the expression of pro-apoptotic protein Bax to a greater extent than did SLE treatment alone. These results suggest that SLE has anti-cancer effect by induction of cellular apoptosis and autophagy. And the apoptotic cell death could be improved by blocking of autophagy in SLE-treated LNCaP cells. However, this effect can be ameliorated by Saussurea lappa is a plant with strong potential as an effective anti-cancer drug for treatment of prostate cancer.

한국 문화관광 공연콘텐츠에 대한 중국관광객의 인식에 관한 콘텐츠정보

XUE FAN 경희대학교 대학원 2019 국내석사

중국 관광객들이 한국 여행에 대한 수요가 지속적으로 상승하고 있는 추세이다. 다양한 한국관광 상품이 중국 관광객의 주목을 받고 있다. 그중에서 K-POP을 시작으로 다양한 한국 문화관광 공연콘텐츠가 중국 관광객의 선호도1순위로 꼽히고 있다. 이런 논의와 함께 본 연구는 다양한 선행연구를 바탕으로 한국 문화관광 공연콘텐츠의 요인이 중국관광객의 만족도에 어떤 영향을 미치는지를 알아보고자 설문조사를 진행하였다. 특히 한국문화관광 공연콘텐츠의 구성요인과 특성요인을 통해 중국관광객들이 한국문화관광 공연콘텐츠를 선택할 때 영향을 미치는 요소들을 자세히 살펴보았다. 단체관광객과 개별관광객도 어떤 차이가 있는지를 분석하였다. 연구 결과, 중국 관광객은 전반적으로 한국 문화관광 공연콘텐츠에 대한 만족도 형성에 기여를 한 것으로 나타났다. 또한 단체관광객과 개별관광객의 만족도에서 유의미한 차이가 있는 것으로 확인되었다. 이러한 연구결과를 바탕으로 중국관광객을 대상으로 하는 한국문화관광 공연콘텐츠의 방향성을 제안해 보았다. 현재 중국관광객이 한국문화관광 공연콘텐츠에 대한 수요가 점점 높아지고 여행하는 유형과 관광목적이 다양해지고 있는 상황에서 이런 연구를 시도했다는데 의의가 있다고 생각한다. With more and more Chinese tourists travel to Korea, the diverse Korean Tourism Products are welcomed by them. Among all the products, the Korean Cultural Tourism Performance become their priority choice due to the prevalence of K-pop in China. A survey about the Korean Cultural Tourism Performance’s structure and feature was taken by those Chinese tourists who watched the performance, aiming at discovering the core factors of choosing a performance and the different ideas on Korean Cultural Tourism Performance between group tourists and independent tourists. It is found that Chinese Tourists are satisfied with the performance and tourists come to Korea with different travel method owns distinct ideas from each other. The research demonstrated that Chinese tourists have high demands to the content of Korean Cultural Tourism Performance and hold positive attitude towards the developmen

Effect of wrapping material, hot water, and storage condition on the maintenance of freshness in cut oriental hybrid lilies

Xue Wei Wu 단국대학교 대학원 2011 국내석사

Physiochemical and Oxidative Characteristics of Structured Lipids Containing Pinolenic Acid

Xue-Mei Zhu 충남대학교 대학원 2011 국내박사

Chapter I 효소 촉매반응을 통해 트리아실글리세롤 분자의 sn-2위치의 피놀산 함량을 향상 보도에 의하면 5-불포화 폴리메틸렌 차단 지방산 (5-UPIFAs)은 잣기름(PN)중 트리아실글리세롤(TAG)의 sn-1,3 위치에 풍부하다. 피놀산산(Pi)은∆5-UPIFAs로써 PN중에서 14.2%를 차지한다. 또한 Pi는 20% 이상이 TAG의 sn - 1 및 / 또는 sn – 3 위치에 자리잡고 있다. 이 연구에서는 효소의 촉매작용에 의한 PN과 팜 스테아린(PS)의 에스테르화반응을 통해 아실 마이그레이션이 일어나면서 sn-2위치의 Pi의 양을 향상시켰다. 반응 후, sn-2위치의 Pi의 비율은 그가 전제 지방산중에서 차이한 양과 비슷하다. 예를 들면 50:50(PN: PS)의 비율로 에스테르화된 생성물 중에서 동일한 양 (7.2%)의 Pi가 sn - 2 및 sn - 1, 3 위치에서 검출되었다. 하지만 파이토스테롤과 토코페롤은 에스테르화반응을 통해 감소되었다는 것이 발견됐다. Chapter II 잣기름과 팜 스테아린의 에스테로화 반응을 통해 만들어진 스틱 마가린의 산화특성 잣기름(PN)과 팜스테아린(PS) 를 각각 40:60, 30:70의 무게비로 혼합하여 Lipozyme TL IM을 촉매로 배치타입의 반응기에서 반응시키면 원하는 스틱 마가린 스톡 (재구성지질, SL)을 얻을 수 있다. 하지만 interesterification과 deacidefication 과정에서 소량으로 존재하는 biocomponts( i.e. 토코페롤)의 손실이 검출되었기에 지질의 산화도 따라서 나타나게 될 것이다. 그래서 카테킨과 로즈마리를 마가린 스톡에 첨가하여 보존 안정성을 약화시킨다. 인덱스 (OSI), 과산화수소 값 (POV), 산가 (AV), p- 아니시딘 (p-AV), 2 – Thiobarituric acid-reactive substances (TBARS) 값, 그리고 TOTOX 값들을 가속화된 산화조건에서 측정하면 물리적인 혼합과 비해 SLs는 더 쉽게 산화의 영향을 받게 된다고 평가되었다. 원래 물리적 혼합반응의 유도시간은 10시간 넘는데 에스테르화반응 후 0.18시간으로 줄어들었다. 다행히 카테킨(800 ppm) 과 로즈마리(2000ppm)를 첨가함으로써 SLs의 유도시간이 효과적으로 증가되었다. 그 결과 POV, AV, p-AV, and TBARS 값이 모두 카테킨과 로즈마리가 산화속도를 늦추거나 막을 수 있다는 것을 표시했다. 카테친은 로즈마리보다 항산화 능력이 뛰여나고 SL에 항산화제의 첨가는 산화를 방지하는 효율적인 방법중의 하나이다. Chapter III 정해진 비율로 Sn-2위치에 피놀산이 함유된 재구성지질과 그 특성 잣기름(PN)과 팜스테아린(PS)을 80:20, 50:50, 그리고 20:80의 무게비로 혼합하여 효소를 촉매로 하는 에스테르화 반응을 통해 제로 트랜스 지방을 만들었다. 반응 후 만들어진 주요한 트리아실글리세롤들은 POL/PLO/OPL, 그리고 POP/PPO 등이 있다. 토탈 지방산중의 ∆5-불포화 폴리메틸렌 차단 지방산 (∆5-UPIFAs)은 3.39-13.69%의 범위로 존재한다. 그리고 sn-2 위치의 Δ5–UPIFAs가 3.53-15.53 %로써 물리적 혼합을 통해 만들어진 양보다 높다. 물리 화학적 반응을 통해 에스테르화된 생성물(SL)은 서로 다른 융해와 결정화 프로필이 있으며 보다 낮은 SFC와 SMP 수치를 나타났다. PN:PS 50:50으로 만들어진 SL의 SFC 값은 10, 20, 30, 그리고 35°C 에서 각각 26.5, 18.46, 8.32, 그리고 2.29% 인데 이는 다른 참고문헌에서 나타난 소프트 튜브 마가린의 값과 비슷하다. 동시에 PN:PS 50:50으로 만들어진 SL의 SMP 값은 31.0°C 로써 이미 보도된 값의 범위 안에 있다. 그래서 PN:PS 50:50으로 만들어진 SL은 소프트 튜브 마가린으로 평가할 수 있다. 또한 PN:PS 20:80으로 만들어진 SL의 SFC값은 10-40°C 에서 12.07-59.95%로 나타났는데 쇼트닝과 비슷하다. 그러므로 PN과 PS로 만들어진 제로 트랜스 지방은 소프트 마가린과 쇼트닝을 만드는데 적합하다. Chapter IV 피놀산이 함유된 재구성 지질중의 α – 토코페롤, 아스코빌 팔미테이트, 그리고 쿼시틴등이 지질 산화에 의한 영향 이 연구는 SL이 30일간 60°C의 조건에서 보존하면서 α-토코페롤(α-TOH), 아스코빌 팔미테이트(AP), 그리고 쿼시틴(Qu) 등이 지방산 중의 Δ5-UPIFAs를 지질 산화에서 보호하여 효과를 조사했다. 보존시 α-TOH를 200과 500 ppm보다 높은 농도로 추가할 때 지질 산화를 가속화 한다. 한편, AP와 Qu는 각 농도에서 높은 항산화효과를 나타났다. 항산화 평가 중에서 Qu는 500ppm에서 가정 효과적이다. 또한 Δ5-UPIFAs를 함유한 SL에 α-TOH, AP, Qu등 항산화제들을 2가지 또는 3가지를 서로 조합하여 각각 100, 500, 그리고 500 ppm의 농도로 첨가하여 서로의 상호작용을 분석했다. 그 중에서 항산화제 AP:Qu와 α-TOH:AP:Qu의 조합이 다른 조합보다 훨씬 효과적이다. Chapter I Enrichment of pinolenic acid at the sn-2 position of triacylglycerol molecules through lipase-catalyzed reaction Reports have shown that ∆5-unsaturated polymethylene interrupted fatty acids (∆5-UPIFAs) are enriched at sn-1, 3 positions of triacylglycerols (TAG) in pine (Pinus koraiensis) nut oil (PN). As a major ∆5-UPIFA, about 14.2% of pinolenic acid (Pi) was determined in PN, while the percentage of Pi at the sn-1 and/or sn-3 positions in TAG was found more than 20%. In this current study, the enhancement of Pi at the sn-2 position has been achieved by acyl migration during the lipase-catalyzed interesterification between PN and palm stearin (PS). After reaction, the proportion of Pi increased at sn-2 positional fatty acid even is similar to that in total fatty acid, e.g. in the interesterified product of 50:50 (PN:PS), the same amount of Pi (7.2%) present were detected both at the sn-2 and sn-1, 3 positions. However, the reduction of phytosterols and tocopherols are observed in the interesterified products. Chapter II Production and oxidative properties of stick margarine interesterified from pine nut oil and palm stearin Desire stick margarine stocks (structured lipids, SL) were prepared from pine nut oil (PN) and palm stearin (PS) in weight ratio of 40:60 and 30:70 which catalyzed by Lipozyme TL IM in a batch type reactor. However, the lost of minor biocomponts (i.e. tocopherol) were detected during the processes of interesterification and deacidefication, which is susceptible to lipid oxidation. Thus, catechin and rosemary were added into the margarine stocks to attenuate the storage stability. Comparing with the physical blends, SLs are susceptible to be oxidized which was assessed by index (OSI), peroxide value (POV), acid value (AV), p-anisidine (p-AV), 2-Thiobarituric acid-reactive substances (TBARS) value, and TOTOX value under accelerate oxidation conditions. The induction time of physical blends is over than 10 h, but decreased to 0.18 h after interesterification. Fortunately, the induction time of SLs were effectively increased by addition of catechin (800 ppm) and rosemary (2000 ppm). The results of POV, AV, p-AV, and TBARS value show that the both catechin and rosemary could inhibit or slow down the oxidation. Catechin exhibits better antioxidant capability than rosemary. The addition of antioxidants to SL is one of efficient way to prevent oxidation. Chapter III Scaled production and characterization of structured lipids containing pinolenic acid at sn-2 position Zero-trans fat were produced by lipase-catalyzed interesterification from pine nut oil (PN) and palm stearin (PS) at a weight ratio of 80:20, 50:50, and 20:80. After reaction, the major triacylglycerols (TAG) were POL/PLO/OPL and POP/PPO. The ∆5-unsaturated polymethylene interrupted fatty acids (∆5-UPIFAs) in total fatty acid are ranged from 3.39-13.69. And 3.53-15.53% of sn-2 positional ∆5-UPIFAs were incorporated which are higher than that in the physical blends, the physical characteristics of the interesterified products (SL) had different melting and crystallization profiles, and showed lower SFC and SMP. SFC of SL-PN:PS 50:50 at 10, 20, 30 and 35°C was 26.5, 18.46, 8.32, and 2.29%, which is similar to the SFC of the soft tube margarine fat in literatures, Besides, SMP of SL-PN:PS 50:50 is 31.0°C in the reported ranges of SMP. Thus, SL-PN:PS 50:50 will be appreciable for soft (tub) margarine. In addition, SL-PN:PS 20:80 had SFC values of 12.07-59.95% at 10-40°C, which are corresponding to the shortening fat. Thus, this zero-trans fat could be suitable for soft margarine and shortenings were produced from PN and PS. Chapter IV Effects of α-tocopherol, ascorbyl palmitate, and quercetin on lipid oxidation in structured lipid containing pinolenic acid This study also investigated the effect of α-tocopherol (α-TOH), ascorbyl palmitate (AP), and quercetin (Qu) on protection of ∆5-UPIFAs in SL against lipid oxidation during storage for 30 days at 60 °C. α-TOH accelerated lipid oxidation during storage when added a concentration above 200 and 500 ppm. In contrast, AP and Qu present strongly antioxidative effect at each concentration. Among the antioxidants evaluated, Qu was found to be the most effective, at the concentration of 500 ppm. In addition, the interaction between the antioxidants, binary or ternary combinations of α-TOH, AP, and Qu were added to SL containing ∆5-UPIFAs at concentrations of 100, 500, and 500 ppm, respectively. Antioxidants of AP:Qu and α-TOH:AP:Qu were significantly effective than the other combinations.

Investigation of the slurry temperature effect during tungsten chemical mechanical planarization

Xue, Wenxing Sungkyunkwan University 2023 국내석사

Till now the semiconductor scale has advanced to a 3-nanometer technology node. The trend of higher integration is to stack more layers with 3D structures in the fabrication process. However, there are so many limitations during the fabrication process to achieve ideal devices. For stacking more layers, one of the urgent issues that should be solved is obtaining a flatter surface as the previous layer was deposited. Chemical mechanical planarization (CMP) is an essential technology to achieve local and global planarization in the semiconductor industry. Many factors can affect the CMP process leading to the generation of defects, especially temperature, which is an important factor in CMP. Many papers have reported the generation of heat and its effect on the CMP process. But still, there is not enough study related to the effect of slurry temperature changes on the CMP process. This study investigated the effects of slurry with different temperatures on tungsten(W) and tetraethyl ortho-silicate (TEOS) CMP through an in-situ heating and cooling system which can control injection slurry temperature. The mechanism under different slurry temperatures was discussed, and it proves that better performance of W CMP can be obtained by the system which was designed to adjust the temperature of solvent-deionized (DI) water from 15℃ to 60℃. For the whole polishing process, an increase in the slurry temperature to 60℃ leads to the increment of the polishing rate and saves the polishing time, thus improving the polishing efficiency by 41% during semiconductor fabrication. On the contrary, decreasing the slurry temperature to 15℃ can reduce the polishing rate of W, reduce the selectivity to 1.87 between metal and TEOS, reduce toughness to Ra 0.573nm, and thus improve the quality and yield of the device. The aim to get better performance of W CMP can come true through the slurry supply system with the changes of temperature in the process.

홍대 지역 버스킹 공연문화의 특수성 연구

Xue, Zhe 홍익대학교 대학원 2020 국내석사

한 · 중 품사 통용의 대조 연구

XUE, YINGYING 이화여자대학교 대학원 2019 국내석사

This study is based on a contrasting study of word class conversions in Korean and Chinese. However, it is not a direct comparison in word class conversions between Korean and Chinese. The purpose of this study is to study the similarities and differences between Korean and Chinese in word class conversions on the basis of the same word classification standards, word system, concept and scope of word class conversions in Korean and Chinese. The chapter Ⅰ served as an introduction, including the purpose, necessity, scope of the study and methods, pre-research. The chapter Ⅱ studied the same Korean and Chinese word classification standards and word system. Both Korean and Chinese have studied the four classification standards of 'meaning', 'function', 'form' and 'distribution' and selected 'function' and 'meaning' as the unified standards for the classification of words in Korean and Chinese. Because there is a big difference between Korean and Chinese word system so this study used the 'meaning' and 'function' as the basis to study the same word system of Korean and Chinese. The unified word system of Korean and Chinese in this article are noun, pronoun, numeral, adjective, adverb, postposition, verb, onomatopoeia, determiner and interjection. The chapter Ⅲ studied the unified concept and scope of word class conversions in Korean and Chinese. The basic concept of word class conversions in Korean and Chinese is a phenomenon in which a word has two or more parts of speech. However, in case of judging the word class conversions, the criteria beyond the basic concept is needed. After discussing their respective standards for judgment of the word class conversions between Korean and Chinese, this study used the same word and significance correlation as the same standards for the judgment of the word class conversions in Korean and Chinese. The chapter Ⅳ showed concrete examples of the word class conversions in Korean and Chinese under the same conditions. In order to facilitate the narrative, Korean uses the noun, adverb, onomatopoeia, pronoun, numeral, adjective to display the examples of the word class conversions. Chinese uses the noun, pronoun, numeral, adjective, verb, onomatopoeia, determiner and interjection to display the examples of the word class conversions. Refer to the above, this study found out the similarities and differences of word class conversions between Korean and Chinese. 본 연구는 한국어와 중국어의 품사 통용에 대한 것으로, 두 언어에서 나타나는 품사 통용 양상에 대한 대조 연구를 전개하였다. 기존의 한·중 품사 통용 연구에서는 항상 한국어와 중국어의 품사 분류 기준과 품사 체계를 각각 정리한 뒤, 이를 중심으로 두 언어의 품사 통용을 대조하고 연구하였다. 반면 본고는 한·중의 품사 분류 기준, 품사 체계, 품사 통용의 개념과 범위를 모두 통일하고 일관된 기준 아래에서 한·중 품사 통용을 대조하여 그 공통점과 차이점을 밝히는 데에 목적을 두었다. Ⅰ장에서는 연구의 목적 및 필요성, 연구 방법을 밝히고 선행 연구를 검토하였다. Ⅱ장에서는 한·중의 품사 분류 기준과 품사 체계를 연구하기 위한 일관된 체계를 세웠다. 한·중 품사 분류 기준에 대해 ‘의미’, ‘기능’, ‘형식’, ‘분포’ 네 가지 기준을 검토하였고, 그 결과 ‘기능’과 ‘의미’를 한·중에 동일하게 적용될 수 있는 품사 분류 기준으로 간주하였다. 한·중 두 언어의 품사 체계는 차이가 크기 때문에, 본고는 ‘의미’와 ‘기능’을 근거로 한·중의 품사 체계를 연구하였다. 그리고 한·중의 공통된 품사 체계로 명사, 대명사, 수사, 의성사, 동사, 형용사, 관형사, 부사, 조사, 감탄사의 10품사를 정하였다. Ⅲ장에서 한·중에서 공통적으로 쓰일 수 있는 품사 통용의 개념과 범위를 검토하였다. 한국어와 중국어의 품사 통용 개념은 대개 ‘한 단어가 두 가지 혹은 두 가지 이상의 품사를 가지는 현상’으로 정의되는데, 품사 통용을 판별하려면 이러한 기본 개념 외에도 판별 기준이 필요하다. 이에 한·중 각각의 품사 통용 판별 기준을 검토하였으며, 그 결과 하나의 단어여야 한다는 점과 의미적으로 상관성을 가져야 한다는 점의 두 가지 기준을 한·중 품사 통용에 동일하게 적용될 수 있는 판별 기준으로 정하였다. Ⅳ장에서는 앞에서 세운 동일한 조건을 기반으로 하여, 품사별로 한·중 품사 통용의 유형별 구체적 예시를 제시하였다. 논의의 편의를 위해 한국어는 명사, 부사, 의성사, 대명사, 수사, 형용사 관련 품사 통용으로 나누어 품사 통용 유형을 제시하였다. 중국어의 경우에는 명사, 동사, 형용사, 관형사, 대명사, 수사, 의성사, 감탄사 관련 품사 통용으로 나누어 품사 통용 유형을 제시하였다. 이와 같이 한·중 품사 통용 양상을 밝힘으로써 한국어와 중국어 각각의 품사 통용 특징을 밝혔고, 이를 바탕으로 한국어와 중국어 품사 통용의 공통점과 차이점을 밝혔다.

중국 생육보험제도의 효과에 대한 연구

XUE YUANYUAN 부경대학교 2022 국내석사

It has been over 70 years since the birth insurance system was introduced in the 1950s to prevent the disconnection of women from economic activities and to solve social risks in Chinese society. This thesis was studied to analyze the effects of the maternity insurance system comprehensively and to derive the system's problems and improvement plans. To this end, this paper conducts a theoretical review of the childbirth insurance system to confirm the institutional significance and policy contents, and then examines the effects of the Chinese childbirth insurance system by using the concept of comprehensive effectiveness of the system such as the input effect, the conversion effect, and the output effect. Based on this, problems and improvement plans of the maternity insurance system were presented. Improving the birth insurance system has been greatly helped to improve women's living standards during childbirth, protect women's reproductive rights and interests, and promote women's enthusiasm for re-participating in production and life after physical recovery. The appropriate adjustment of maternity treatment enables the baby to receive better care and companionship and grow up healthier. It has a positive effect on women's equal employment. Businesses with more women bear higher childbearing costs than those with fewer women. It is easy to cause the cost imbalance of enterprises. As a result, many companies are reluctant to hire women. By providing maternity protection, the pressure on employers to bear birth insurance is reduced, the opportunities for equal employment between men and women are increased, and the development of enterprises is promoted. It is conducive to fair competition, and through comprehensive consideration of the cost of recruiting women by enterprises, it protects fair competition of enterprises and promotes the benign development of social economy.