Selection response and estimation of the genetic parameters for multidimensional measured breast meat yield related traits in a long-term breeding Pekin duck line

Xu, Yaxi,Hu, Jian,Zhang, Yunsheng,Guo, Zhanbao,Huang, Wei,Xie, Ming,Liu, Hehe,Lei, Chuzhao,Hou, Shuisheng,Liu, Xiaolin,Zhou, Zhengkui Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.10

Objective: This study was conducted to estimate the genetic parameters and breeding values of breast meat related traits of Pekin ducks. Selection response was also determined by using ultrasound breast muscle thickness (BMT) measurements in combination with bosom breadth (BB) and keel length (KL) values. Methods: The traits analyzed were breast meat weight (BMW), body weight (BW), breast meat percentage (BMP) and the three parameters of breast meat (BB, KL, and BMT). These measurements were derived from studying 15,781 Pekin ducks selected from 10 generations based on breast meat weight. Genetic parameters and breeding value were estimated for the analysis of the breeding process. Results: Estimated heritability of BMW and BMP were moderate (0.23 and 0.16, respectively), and heritability of BW was high (0.48). Other traits such as BB, KL, and BMT indicated moderate heritability ranging between 0.11 and 0.28. Significant phenotypic correlations of BMW with BW and BMP were discovered (p<0.05), and genetic correlations of BMW with BW and BMP were positive and high (0.83 and 0.66, respectively). It was noted that BMW had positive correlations with all the other traits. Generational average estimated breeding values of all traits increased substantially over the course of selection, which demonstrated that the ducks responded efficiently to increased breast meat yield after 10 generations of breeding. Conclusion: The results indicated that duck BMW had the potential to be increased through genetic selection with positive effects on BW and BMP. The ultrasound BMT, in combination with the measurement of BB and KL, is shown to be essential and effective in the process of high breast meat yield duck breeding.

Organo-layered double hydroxides for the removal of polycyclic aromatic hydrocarbons from soil washing effluents containing high concentrations of surfactants

Zhang, Ming,Zhao, Cheng,Li, Jinye,Xu, Liheng,Wei, Fang,Hou, Deyi,Sarkar, Binoy,Ok, Yong Sik Elsevier 2019 Journal of hazardous materials Vol.373 No.-

<P><B>Abstract</B></P> <P>Disposal of soil washing effluent (SWE) resulting from the surfactant-enhanced remediation of soil containing hydrophobic organic contaminants (HOCs)is complicated because of the presence of high levels of surfactants. The synthesized layered double hydroxides (LDHs), modified with sodium dodecyl sulfonate (SDS) in different loading amounts (organo-LDHs),were evaluated in this study as sorbents for the removal of two typical HOCs, phenanthrene (PHE) and pyrene (PYR),from a simulative SWE. The results showed that the organo-LDHs can effectively sorb PHE and PYR from the SWE within an equilibrium time of 2 h. All isotherms were linear and the sorption capabilities of the organo-LDHs increased almost linearly with the increase in the amount of SDS loaded on the LDHs. Besides, the surface areas of the organo-LDHs decreased sharply with the increase in SDS loading owing to the hindrance of the exposed surface of the LDHs by the incorporated SDS. These findings indicated that partitioning dominated the sorption process rather than adsorption, and the strong affinity of HOCs towards the organic phase in LDHs assisted in the effective removal of polycyclic aromatic hydrocarbons (PAHs) from the SWE. Furthermore, the sorption capabilities of organo-LDHs towards PHE and PYR at the higher loading amounts of SDS were much greater than that of commercial activated carbon at the higher concentration ranges of PAHs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Dodecyl sulfonate anion modified LDHs are employed for the removal of PHE and PYR in soil washing effluent (SWE). </LI> <LI> Organo-LDHs showed superior performance in PHE removal from SWE than that of commercial activated carbon. </LI> <LI> Partitioning of PHE and PYR in the organic fraction of the organo-LDHs was the main mechanism. </LI> <LI> Using organo-LDHs for the separation of HOCs from surfactants in SWE facilitated reuse of the surfactants. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Control Strategy and Characteristic Analysis of Hybrid Active Power Filters with the Resonant Impedance Principle

Fang, Lu,Xu, Xian-Yong,Luo, An,Li, Yan,Tu, Chun-Ming,Fang, Hou-Hui The Korean Institute of Power Electronics 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.6

A new kind of resonant impedance type hybrid active filter (RITHAF) is proposed for dynamic harmonic current suppression and high capacity reactive compensation in medium and high voltage systems. This paper analyzed the different performance of the RITHAF when the active part of the RITHAF is controlled as a current source and as a voltage source, respectively. The harmonic suppression function is defined in this paper. The influences of the changes caused by the grid impedance and the detuning of the passive power filter on the compensating characteristics of the RITHAF are studied by analyzing the suppression function. Simulation and industrial application results show that the RITHAF has excellent performances in harmonic suppression and reactive compensation, which is suitable for medium and high voltage systems.

Control Strategy and Characteristic Analysis of Hybrid Active Power Filters with the Resonant Impedance Principle

Lu Fang,Xian-yong Xu,An Luo,Yan Li,Chun-ming Tu,Hou-hui Fang 전력전자학회 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.6

A new kind of resonant impedance type hybrid active filter (RITHAF) is proposed for dynamic harmonic current suppression and high capacity reactive compensation in medium and high voltage systems. This paper analyzed the different performance of the RITHAF when the active part of the RITHAF is controlled as a current source and as a voltage source, respectively. The harmonic suppression function is defined in this paper. The influences of the changes caused by the grid impedance and the detuning of the passive power filter on the compensating characteristics of the RITHAF are studied by analyzing the suppression function. Simulation and industrial application results show that the RITHAF has excellent performances in harmonic suppression and reactive compensation, which is suitable for medium and high voltage systems.

Extraction of hyper-elastic material parameters using BLSTM neural network from instrumented indentation

Jing Jin Shen,Jia Ming Zhou,Shan Lu,Yue Yang Hou,Rong Qing Xu 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.12

Instrumented indentation is a versatile method of extracting hyper-elastic material parameters, particularly useful for applications where stress-strain data are difficult to be insitu measured. Because the analytical force-displacement relation is still unavailable for the indentation of hyper-elastic materials, identifying hyper-elastic parameters often requires an iterative optimization strategy that fits finite element simulations with experimental data. However, the optimization strategy is burdened by heavy computation and its prediction accuracy is greatly influenced by the choice of optimization algorithm. To address these challenges in this study, a bidirectional long short-term memory (BLSTM) neural network is presented that directly predicts hyper-elastic material parameters from indentation load-displacement data, focusing on Mooney-Rivlin hyper-elasticity as an example. To improve the predication accuracy, the condition numbers for the inverse identification of the hyper-elastic parameters are investigated. And, a normalization procedure is proposed to treat the input data, which can guarantee the BLSTM network is well-conditioned. During evaluation, the trained BLSTM network significantly outperforms the iterative optimization strategy using a genetic algorithm. Furthermore, the effect of the normalization procedure is demonstrated.

Vertebral Artery Variations at the Craniovertebral Junction in “Sandwich” Atlantoaxial Dislocation Patients

Yinglun Tian,Nanfang Xu,Ming Yan,Jinguo Chen,Kan-Lin Hung,Xiangyu Hou,Shenglin Wang,Weishi Li 대한척추신경외과학회 2021 Neurospine Vol.18 No.4

Objective: To summarize the vertebral artery (VA) pattern of 96 “sandwich” atlantoaxial dislocation (AAD) patients and to describe the strategies of reducing the injury of VA during surgery. Methods: From 2009 to 2020, we retrospectively reviewed the 3-dimensional computed tomography angiography data of 96 AAD patients combined with atlas occipitalization and C2–3 fusion, which were diagnosed as “sandwich” AAD and 96 patients as control group patients who were without atlas occipitalization, C2–3 fusion and any other cervical bone deformity at our institution. The variations of each side of VA were described in 3 different parts (C0–1, C1–2, and C2–3) according to the characteristics of the 3-part pathological structures in “sandwich” subgroup. Results: One hundred ninety-two sides of VAs in every group of patients were analyzed and every VA was described separately at 3 different level regions. There were different variations in these 3 different regions: 4 variations in the upper fusion region, 5 variations in the sandwiched region, and 6 variations in the lower fusion region in sandwich AAD patients. And the rate of VA deformity in sandwich AAD patients was much higher and more types of VA variations existed. Conclusion: In “sandwich” AAD patients, deformities of vertebral arteries in craniovertebral junction are more common, and the same VA may have deformities at different levels that severely affect surgical procedures. Therefore, preoperative imaging examination of VA for “sandwich” AAD patients is vital of guiding surgeons to avoid injury of VA during surgery.

Efficient slope reliability analysis using a surrogate-assisted normal search particle swarm optimization algorithm

Yuan Yi-li,Hu Chang-ming,LI LIANG,Hou Xu-hui 한국CDE학회 2024 Journal of computational design and engineering Vol.11 No.1

Sampling of training data is the most important step in active learning slope reliability analysis, which controls the analysis accuracy. In this study, a novel surrogate-assisted normal search particle swarm optimization (SANSPSO) was proposed to enhance the accuracy and robustness of existing methodologies. In SANSPSO, the sampling process was considered a minimum problem with an objective function defined as the absolute value of the performance function. Initiated with a normal search paradigm and supplemented by three algorithm strategies, this approach seeks to preserve the continuity of the solution while refining the algorithm’s efficacy and efficiency. To reduce computation cost, surrogate-assistance was used, in which a surrogate model substitutes the objective function in most iterations. This surrogate model evolves during the iteration process and ultimately replaces the actual performance function within Monte Carlo simulation. Finally, this study presents a comparative study with five state-of-the-art methods across four explicit problems and three engineering cases, where test data suggest that the SANSPSO methodology yields a 20% improvement in accuracy and a 30% rise in stability under different dimensional problems relative to the most efficacious of the alternate methods assessed because of the improved and more consistent prediction of limit state function. These findings substantiate the validity and robustness of the SANSPSO approach.

ADRVis : an Information Visualization Platform for Adverse Drug Reactions

Wei Jian-Xiang,Zhu Yun-Xia,Sun Jun,Xu Hou-Ming,Li Ming,Sun Yue-Hong 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.10

Adverse drug reactions (ADRs) are a serious threat to people's lives and property safety. Currently, drug instructions are the main way for people to obtain information on ADRs. Due to drugs’ limited pre-market clinical trials, adverse reactionsstated in drug instructions are often not sufficient. Avisualization platform for ADRs isput forward to address this problem. Adverse drug events (ADEs) data include actual clinical adverse reactions of drugs detected by drug monitoring administrationand can compensate for the insufficiency of drug instructions. Based on drug instructions and ADEs data, ADRVis isrealized by data analysis, model design and JAVA programming. ADRVis presentsthe relationship of 656 common drugs and their respective ADRs. Three case studies show that the platform has the capacities of visual presentation of ADRs and early warning of drug risks.The platform can provide people more rich information about drugs and help them understand ADRs more accurately and comprehensively.

EMP3 Overexpression in Primary Breast Carcinomas is not Associated with Epigenetic Aberrations

Wei Zhou,Jinming Yu,Zheng Jiang,Xingang Li,Fenghua Xu,Yanbing Liu,Peie Wen,Li Kong,Ming Hou,Jinming Yu 대한의학회 2009 Journal of Korean medical science Vol.24 No.1

Epithelial membrane protein 3 (EMP3) is a trans-membrane signaling molecule with important roles in the regulation of apoptosis, differentiation and invasion of cancer cells, but the detailed is largely still unknown. We analyzed the mRNA levels and methylation statuses of EMP3 in 63 primary breast carcinomas and assessed their correlations with clinicopathologic variables. The expression of EMP3 mRNA in primary breast carcinomas was significantly higher than the expression of 20 normal breast tissues (p<10-7). EMP3 overexpression in breast carcinomas was significantly related to histological grade III (p=3.9×10-7), lymph node metastasis (p= 0.003), and strong Her-2 expression (p=3.3×10-6). Hypermethylation frequencies of EMP3 were detected in 36.5% of breast carcinomas by methylation-specific polymerase chain reaction. However, no significant correlations were found between methylation status of EMP3 and mRNA expression levels as well as other clinical parameters. In conclusion, EMP3 may be a novel marker of tumor aggressiveness. Overexpression of EMP3 in primary breast carcinoma is not associated with DNA methylation.

Meta-analysis of the Efficacy of Sorafenib for Hepatocellular Carcinoma

Wang, Zhao,Wu, Xiao-Ling,Zeng, Wei-Zheng,Xu, Gui-Sen,Xu, Hui,Weng, Min,Hou, Juan-Ni,Jiang, Ming-De Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

Purpose: By carrying out a meta-analysis of randomized controlled trials that compared sorafenib or combined chemotherapy with placebo or combined chemotherapy, the effectiveness of sorafenib in hepatocellular carcinoma was evaluated in the present study, which also provided clinical practice guidelines of evidence-based-medicine. Methods: We reviewed PubMed citations concerning sorafenib treating hepatocellular carcinoma in randomized controlled trials from Jan 2000 to July 2012. All the literature was extracted by Cochrane systematic reviews and underwent meta-analysis with RewMan 5.0 software. Results: Finally, four papers documenting randomized controlled studies were included. Compared with controls, sorafenib was shown to significantly increase overall survival (OS), time to progression (TTP), and disease control rates (DCR), but not the time to symptom progression (TTSP) in hepatocellular carcinoma patients. The incidence of grade-III/IV adverse reactions, including hand-foot-skin reactions, diarrhea, hypertension and skin rash or desquamation, in sorafenib treatment group was higher than that in controls. However, there was no significant difference in the incidence of hypodynamia between the two groups. Conclusions: Sorafenib exerts significant curative effects in hepatocellular carcinoma.