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      • KCI등재

        Neurotoxicity of acrylonitrile evaluated by manganese enhanced magnetic resonance imaging

        Ying Li,Lihong Mei,Jinwei Qiang,Chi-Shing Zee,Xiuju Li,Junhua Liu 대한독성 유전단백체 학회 2015 Molecular & cellular toxicology Vol.11 No.3

        Acrylonitrile (ACN), a chemical compound commonly used to manufacture plastics, has been found in drin king water and as a pollutant in the air. Exposure to high levels of ACN leads to brain lesions via oxidative stress-induced injury. To date, there is no non-invasive method of examining brain lesions. We determined if manganese-enhanced magnetic resonance imaging (MEMRI) can be used to detect brain lesions in ACN-treated rats by exploiting the binding properties of manganese to the enzymes manganesesuperoxide dismutase (Mn-SOD) and glutamine synthetase (GS). Rats exposed to low, mid, and high doses of ACN over 7 days were subjected to MEMRI on the eighth day. Contrast enhancement of the brain decreased in ACN-treated rats, along with marked decreases in Mn-SOD and GS activities, particularly in mid- and high-ACN treated rats. Our study indicates that MEMRI may be a potential non-invasive method of detecting ACN-induced oxidative damage.

      • SCOPUSKCI등재

        MIL-53(Fe)@γ-Al₂O₃ nanocomposites incorporated cellulose acetate for forward osmosis membranes of high desalination performance

        Tong Li,Xuelian Ba,Xiuju Wang,Zhongpeng Wang,Jie Yang,Yu Cui,Liguo Wang 대한환경공학회 2023 Environmental Engineering Research Vol.28 No.1

        Forward osmosis (FO) membrane is a promising membrane technique. However, its application in desalination is limited. Thus, we synthesized MIL-53(Fe)@γ-Al₂O₃ via solvent-thermal method to fabricate MIL-53(Fe)@γ-Al₂O₃/cellulose acetate (CA) composite membranes of high desalination performance. MIL-53(Fe)@γ-Al₂O₃ and MIL-53(Fe) particles were studied using XRD, FITR, SEM, N₂ adsorption-desorption isotherms, and AFM. The structural features of MIL-53(Fe)@γ-Al₂O₃/CA membrane and MIL-53(Fe)/CA membrane were analyzed using SEM, AFM and water contact angle. The reverse salt flux and water flux of the MIL-53(Fe)@γ-Al₂O₃/CA membrane reached 1.78 g m<SUP>-2</SUP> h<SUP>-1</SUP> and 37.1 L m<SUP>-2 </SUP>h<SUP>-1</SUP>, respectively, when the deionized water and 1 M NaCl solution were the feed solution and traction solution, respectively. Compared to the MIL-53(Fe)/CA membrane, the MIL-53(Fe)@γ-Al₂O₃/CA membrane demonstrated better perviousness and selectivity properties of the membrane. This study shows a potential advantage of MOF composites as additives for improvement in the desalination performance of forward osmosis membranes.

      • KCI등재

        MIL-53(Fe)@γ-Al2O3 nanocomposites incorporated cellulose acetate for forward osmosis membranes of high desalination performance

        Tong Li,Xuelian Ba,Xiuju Wang,Zhongpeng Wang,Jie Yang,Yu Cui,Liguo Wang 대한환경공학회 2023 Environmental Engineering Research Vol.28 No.1

        Forward osmosis (FO) membrane is a promising membrane technique. However, its application in desalination is limited. Thus, we synthesized MIL-53(Fe)@γ-Al2O3 via solvent-thermal method to fabricate MIL-53(Fe)@γ-Al2O3/cellulose acetate (CA) composite membranes of high desalination performance. MIL-53(Fe)@γ-Al2O3 and MIL-53(Fe) particles were studied using XRD, FITR, SEM, N2 adsorption-desorption isotherms, and AFM. The structural features of MIL-53(Fe)@γ-Al2O3/CA membrane and MIL-53(Fe)/CA membrane were analyzed using SEM, AFM and water contact angle. The reverse salt flux and water flux of the MIL-53(Fe)@γ-Al2O3/CA membrane reached 1.78 g m−2 h−1 and 37.1 L m−2 h−1, respectively, when the deionized water and 1 M NaCl solution were the feed solution and traction solution, respectively. Compared to the MIL-53(Fe)/CA membrane, the MIL-53(Fe)@γ-Al2O3/CA membrane demonstrated better perviousness and selectivity properties of the membrane. This study shows a potential advantage of MOF composites as additives for improvement in the desalination performance of forward osmosis membranes.

      • KCI등재

        A repressor motif-containing poplar R3 MYB-like transcription factor regulates epidermal cell fate determination and anthocyanin biosynthesis in Arabidopsis

        Qingnan Hu,Li Yang,Shanda Liu,Limei Zhou,Xutong Wang,Wei Wang,Ling Cai,Xiuju Wu,Ying Chang,Shucai Wang 한국식물학회 2016 Journal of Plant Biology Vol.59 No.5

        Single-repeat R3 MYB transcription factors (R3 MYBs) regulate epidermal cell fate determination in Arabidopsis through a lateral inhibition mechanism. Previously we have shown that poplar R3 MYB genes regulate trichome formation when expressed in Arabidopsis. Here we report the identification and functional characterization of a poplar R3 MYB-like protein, Populus trichocarpa R3 MYB-LIKE1 (PtrRML1). So far all the MYB transcription factors identified have a highly conserved N-terminal DNA-binding domain composed of MYB repeats and a highly variable C-terminal domain. However, PtrRML1 has a single R3 MYB repeat at its C-terminal and an LxLxL repressor motif-containing N-terminal, and with amino acids about twice of that of the known R3 MYBs. PtrRML1 is localized in nuclear in transgenic Arabidopsis plants expressing PtrRML1-GFP. PtrRML1 repressed reporter gene expression in protoplasts, and it interacted with GL3 in plant cells. Expression of PtrRML1 in Arabidopsis resulted in glabrous phenotypes, increased number of root hairs, and decreased anthocyanin accumulation. Consist with these observation, the expression levels of some MBW component genes and some of their target genes involved in the regulation of epidermal cell fate determination and anthocyanin biosynthesis, including TRY, CPC, ETC1, GL1, GL2, DFR, UF3GT and TT8 were reduced in the transgenic plants.

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