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Jiankun Xiong,Haibo Zhang,Fuheng Nie,Fen He,Jianping Yang,Zhan Hu,Zhongbo Wen,Haiyan Zhao,Xinjian Yuan 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7
The formation mechanisms for two carbides with co-existence and increasing stacking faults nearby the carbides duringsurfacing welding were investigated in this study. The results indicated that the surfacing layer had a two-phase structure ofa matrix phase and a second phase, the density of the second phase was relatively small and the second phase was discontinuous,by contrast with the as-received welding wire. Relatively uniform microstructure of surfacing layer and the weldinginterface without melting of base metal were obtained, resulting in an inapparent change in the microhardness. A few carbideswith blocky shape were identified in the surfacing layer. The mechanisms for (Cr,Co)23C6 of face-centered cubic crystalstructure co-existing with (Cr,Co)7C3 of hexagonal close-packed crystal structure and (Cr,Co)23C6 subsequently forming closeto the pre-formed (Cr,Co)7C3 during the cooling process were discussed in alloying element, calculated equilibrium phasediagram, Gibbs energy, etc. The relatively higher density of the stacking fault present around the carbides was understoodfrom forming energy of stacking faults.
Roles of Immunohistochemical Staining in Diagnosing Pulmonary Squamous Cell Carcinoma
Yan, Yue,Zhang, Ya-Xiong,Fang, Wen-Feng,Kang, Shi-Yang,Zhan, Jian-Hua,Chen, Nan,Hong, Shao-Dong,Liang, Wen-Hua,Tang, Yan-Na,He, Da-Cheng,Wu, Xuan,Zhang, Li Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2
Background: Differentiating morphologic features based on hematoxylin-eosin (HE) staining is the most common method to classify pathological subtypes of non-small-cell lung cancer (NSCLC). However, its accuracy and inter-observer reproducibility in pathological diagnosis of poorly differentiated NSCLC remained to be improved. Materials and Methods: We attempted to explore the role of immunohistochemistry (IHC) staining in diagnosing pulmonary squamous cell carcinoma (SQCC) with poorly differentiated features by HE staining or with elevated serum adenocarcinoma-specific tumor markers (AD-TMs). We also compared the difference of epidermal growth factor receptor (EGFR) mutation rate between patients with confirmed SQCC and those with revised pathological subtype. Logistic regression analyses were used to test the association between different factors and diagnostic accuracy. Results: A total of 132 patients who met the eligible criteria and had adequate specimens for IHC confirmation were included. Pathological revised cases in poor differentiated subgroup, biopsy samples and high-level AD-TMs cases were more than those with high/moderate differentiation, surgical specimens and normal-level AD-TMs. Moreover, biopsy sample was a significant factor decreasing diagnostic accuracy of pathological subtype (OR, 4.037; 95% CI 1.446-11.267, p=0.008). Additionally, EGFR mutation rate was higher in patients with pathological diagnostic changes than those with confirmed SQCC (16.7% vs 4.4%, p=0.157). Conclusions: Diagnosis based on HE staining only might cause pathological misinterpretation in NSCLC patients with poor differentiation or high-level AD-TMs, especially those with biopsy samples. HE staining and IHC should be combined as pathological diagnostic standard. The occurrence of EGFR mutations in pulmonary SQCC might be overestimated.
Xiong, Wei,Jiang, Yong-Xin,Ai, Yi-Qin,Liu, Shan,Wu, Xing-Rao,Cui, Jian-Guo,Qin, Ji-Yong,Liu, Yan,Xia, Yao-Xiong,Ju, Yun-He,He, Wen-Jie,Wang, Yong,Li, Yun-Fen,Hou, Yu,Wang, Li,Li, Wen-Hui Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8
Background: Preoperative 5-fluorouracil (5-FU)-based chemoradiotherapy is a standard treatment for locally advanced colorectal cancer (CRC). However, CRC cells often develop chemoradiation resistance (CRR). Recent studies have shown that long non-coding RNA (lncRNA) plays critical roles in a myriad of biological processes and human diseases, as well as chemotherapy resistance. Since the roles of lncRNAs in 5-FU-based CRR in human CRC cells remain unknown, they were investigated in this study. Materials and Methods: A 5-FU-based concurrent CRR cell model was established using human CRC cell line HCT116. Microarray expression profiling of lncRNAs and mRNAs was undertaken in parental HCT116 and 5-FU-based CRR cell lines. Results: In total, 2,662 differentially expressed lncRNAs and 2,398 mRNAs were identified in 5-FU-based CRR HCT116 cells when compared with those in parental HCT116. Moreover, 6 lncRNAs and 6 mRNAs found to be differentially expressed were validated by quantitative real time PCR (qRT-PCR). Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis for the differentially expressed mRNAs indicated involvement of many, such as Jak-STAT, PI3K-Akt and NF-kappa B signaling pathways. To better understand the molecular basis of 5-FU-based CRR in CRC cells, correlated expression networks were constructed based on 8 intergenic lncRNAs and their nearby coding genes. Conclusions: Changes in lncRNA expression are involved in 5-FU-based CRR in CRC cells. These findings may provide novel insight for the prognosis and prediction of response to therapy in CRC patients.
Direct ethanol production from dextran industrial waste water by Zymomonas mobilis
Ming-xiong He,Han Qin,Xiao-bo Yin,Zhi-yong Ruan,Fu-rong Tan,Bo Wu,Zong-xia Shui,Li-chun Dai,Qi-chun Hu 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.11
The direct production of ethanol from dextran industrial waste water was investigated by using Zymomonasmobilis via batch and semi-continuous fermentation mode. In batch fermentation, pretreated waste water (unsterilizedand sterilized), pH value (3.8 and 6.0), and Mg2+(with and without) was compared with OD600, sugar and ethanol con-centration. After 24 h fermentation, sugar in the dextran waste water was almost exhausted, and the amount of ethanolaccumulated reached 24.33-29.92 g/l, which is nearly 99% of the theoretical yield of ethanol. Kinetic parameters ofZ. mobilis in batch fermentation were also investigated. The raw dextran waste water was also used in semi-continuousfermentation. After 48 h fermentation, the production of ethanol was 28.65 g/l. These results indicated that dextranwaste water may be used as a candidate substrate and Z. mobilis could convert the raw material into ethanol directly.
Research of Face Recognition System Based on Visual Intelligent Monitoring
He Zhiliang,Xiong Juntao,Mai Zhiheng,Zhong Pengfei,Tang Linyue 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.5
The key technology of intelligent face recognition based on the visual monitoring was researched. Firstly, obtained the real-time scene by video camera, and the background difference method was used to judge whether there is a character goal in monitoring region, in view of the existing target, the color space of YCgCr and YCgCb were chosen to detect skin color, the geometric constraints that the aspect ratio of facial contour is 0.8 to 1.85 was used to realize the positioning of face region. Then the improved 2DPCA algorithm was used for face recognition, and data matching with the established database of face to determine the validity character identity. Finally the identification results were sent to the mobile terminal through the control system. System test results show that the processing speed of face recognition is 7 s/times, and the accuracy of face recognition results was 85%, which can provide technical support for the identity intelligent recognition of visual monitoring.
Xiong Zhiyong,Wen Zhuoqi,Cui Zhongjie,Mei Shiliang,He Haiyang,Duan Zhongtao,Zhang Wanlu,Xie Fengxian,Guo Ruiqian 한국물리학회 2023 Current Applied Physics Vol.45 No.-
Hysteresis effects in self-luminous devices like organic light-emitting diodes (OLEDs) and perovskite light-emitting diodes (PeLEDs) have been discovered recently, besides emerging in thin film transistors (TFTs). However, the influences of lateral leakage caused by next-door devices on hysteresis effects in flexible OLEDs array have rarely been demonstrated. To mitigate the impact of lateral leakage and figure out the detailed relationship with hysteresis effects, a series of experiments for OLEDs array involving p-doping in holes transport layer (HTL) were employed. It is found that the lateral leakage and hysteresis effects have a trade-off exhibition, which means stronger lateral leakage has induced weaker hysteresis effects. In order to get rid of the role of lateral leakage, the experiments with mono blue devices were also performed to substantiate the intrinsic hysteresis effects existence. The research opens the possibility of considering more internal relationships between different performances on self-luminous arrays for their actual application.
A Vibration Signal Analysis Method based on Enforced De-Noising and Modified EMD
He jun,Qinghua Zhang,Guoxi Sun,Ji-cheng Yang,Jianbin Xiong 보안공학연구지원센터(IJSIP) 2015 International Journal of Signal Processing, Image Vol.8 No.1
To deal with the noise from rotating machinery vibration signal and analysis the fault signal, a rotating machinery fault diagnosis method based on enforced de-noising and modified EMD is proposed. Firstly, fault signals were de-noised by the wavelet with enforced threshold in order to filter the noises in the high frequency, and then the EMD method used to decompose the fault signals into a finite number of stationary intrinsic mode function (IMFs), then the linear correlation coefficient between two sets of data is proposed to select the useful IMF. In order to restrain the endpoint effect of EMD, in this paper, the cosine window function is employ to the fault signals, and then the envelope error of the fault signals is controlled at the both endpoints of the vibration signals. Experimental results shows: this proposed method can extract the fault information effectively, with overcoming the drawbacks of EMD well.
LCL-T resonant network-based modular multi-channel constant-current LED driver analysis and design
He, Qingqing,Luo, Quanming,Huang, Jian,Cao, Chi,Sun, Pengju,Du, Xiong The Korean Institute of Power Electronics 2020 JOURNAL OF POWER ELECTRONICS Vol.20 No.6
Multiple output LED drivers are necessary to achieve better performance and higher reliability in street lighting, tunnel lighting and LCD background lighting applications. Based on LCL-T constant-current characteristics, a modular multiple output LED driver is proposed in this paper. The LCL-T rectifiers are connected to the same voltage bus and work like current sources. However, since there are much higher voltage harmonics in the AC square bus voltage, it is very important to quantitatively analyze how these harmonics influence the precision of the output currents. In addition, all of the switches can achieve Zero Voltage Switching (ZVS) by proper design of the LCL-T network. Finally, a 200-W prototype with five channels is established with an efficiency of 92.25%.
Review of the Molecular Pathogenesis of Osteosarcoma
He, Jin-Peng,Hao, Yun,Wang, Xiao-Lin,Yang, Xiao-Jin,Shao, Jing-Fan,Guo, Feng-Jin,Feng, Jie-Xiong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Treating the osteosarcoma (OSA) remains a challenge. Current strategies focus on the primary tumor and have limited efficacy for metastatic OSA. A better understanding of the OSA pathogenesis may provide a rational basis for innovative treatment strategies especially for metastases. The aim of this review is to give an overview of the molecular mechanisms of OSA tumorigenesis, OSA cell proliferation, apoptosis, migration, and chemotherapy resistance, and how improved understanding might contribute to designing a better treatment target for OSA.