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Biomechanical Mechanism of Fabric Softness Discrimination
Hu, Jiyong,Ding, Xin,Wang, Rubin The Korean Fiber Society 2007 Fibers and polymers Vol.8 No.4
"Softness" is one of the primitive terms describing the physical and sensory attributes of fabric, however, the information for its physiological mechanism compared to statistical physical factors of fabric softness is scarce. To explain the biomechanical and the potential neurophysiological phenomenon for exploring fabric softness, a finger-fabric finite element model is used to conduct an active contact simulation analysis. The effects of surface friction index and compression modulus of fabric on softness discrimination are investigated. The interests of the study are in the contributions of these fabric variables to the changing contact area, interfacial fiction shear stress and contact pressure distributions, which are significant cognitive variables or stimulus parameters in peripheral neural levels documented by prior observations. The mechanistic data for fingerpad-fabric interaction indicate that the basis for the perception of softness of flexible and bulk fabric is likely on the spatial variation of the pressure and shear stress on the skin resulting from the surface friction index and compression property of fabric. These conclusions suggest that devices for the haptic rendering of fabric softness, based on vibration result from surface roughness, is not sufficient to perceive the soft-touch feel of fabric as a result of the cues with lack information for the changing contact area by touch.
Hu, Zheng-Hui,Lin, Yi-Wei,Xu, Xin,Chen, Hong,Mao, Ye-Qing,Wu, Jian,Zhu, Yi,Xu, Xiang-Lai,Xie, Li-Ping Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1
Background: Many studies have investigated associations between the glutathione S-transferase M1 (GSTM1) null polymorphism and risk of prostate cancer, but the impact of GSTM1 in people who live in Asian countries is still unclear owing to inconsistencies across results. Methods: We searched the PubMed, Web of Science, Scopus, Ovid and CNKI databases for studies of associations between the GSTM1 null genotype and risk of prostate cancer in people who live in Asian countries, and estimated summary odds ratios (ORs) with 95% confidence intervals (95% CIs). Results: A total of 18 case-control studies with 2,172 cases and 3,258 controls were included in this meta-analysis, which showed the GSTM1 null genotype to be significantly associated with increased risk of prostate cancer in people who live in Asian countries (random-effects OR=1.74, 95% CI1.44-2.09, P<0.001). Similar results were found in East Asians (OR=1.41; 95% CI: 1.12-1.78; P=0.004) and Caucasians in Asia (OR=2.19; 95% CI: 1.85-2.60; P<0.001). No evidence of publication bias was observed. Conclusions: This meta-analysis of available data suggested that the GSTM1 null genotype does contribute to increased risk of prostate cancer in people who live in Asian countries.
Hu, Zheng-Hui,Lin, Yi-Wei,Xu, Xin,Chen, Hong,Mao, Ye-Qing,Wu, Jian,Xu, Xiang-Lai,Zhu, Yi,Li, Shi-Qi,Zheng, Xiang-Yi,Xie, Li-Ping Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3
Objective: To evaluate the association between tea consumption and the risk of renal cell carcinoma. Methods: We searched PubMed, Web of Science and Scopus between 1970 and November 2012. Two evaluators independently reviewed and selected articles based on predetermined selection criteria. Results: Twelve epidemiological studies (ten case-control studies and two cohort studies) were included in the final analysis. In a meta-analysis of all included studies, when compared with the lowest level of tea consumption, the overall relative risk (RR) of renal cell carcinoma for the highest level of tea consumption was 1.03 (95% confidence interval [CI] 0.89-1.21). In subgroup meta-analyses by study design, there was no significant association between tea consumption and renal cell carcinoma risk in ten case-control studies using adjusted data (RR=1.08, 95% CI 0.84-1.40). Furthermore, there was no significant association in two cohort studies using adjusted data (RR=0.95, 95% CI 0.81-1.12). Conclusion: Our findings do not support the conclusion that tea consumption is related to decreased risk of renal cell carcinoma. Further prospective cohort studies are required.
Colorimetric and Fluorescent Detecting Phosgene by a Second-Generation Chemosensor
Hu, Ying,Zhou, Xin,Jung, Hyeseung,Nam, Sang-Jip,Kim, Myung Hwa,Yoon, Juyoung American Chemical Society 2018 ANALYTICAL CHEMISTRY - Vol.90 No.5
<P>Because of the current shortage of first-generation phosgene sensors, increased attention has been given to the development of fluorescent and colorimetric based methods for detecting this toxic substance. In an effort focusing on this issue, we designed the new, second-generation phosgene chemosensor <B>1</B> and demonstrated that it undergoes a ring-opening reaction with phosgene in association with color and fluorescent changes with a detection limit of 3.2 ppb. Notably, in comparison with the first-generation sensor RB-OPD, <B>1</B> not only undergoes a much faster response toward phosgene with an overall response time within 2 min, but it also generates no byproducts during the sensing process. Finally, sensor <B>1</B> embedded nanofibers were successfully fabricated and used for accurate and sensitive detection of phosgene.</P> [FIG OMISSION]</BR>
Nrf2 Overexpression Predicts Prognosis and 5-FU Resistance in Gastric Cancer
Hu, Xiu-Feng,Yao, Jun,Gao, She-Gan,Wang, Xin-Shuai,Peng, Xiu-Qing,Yang, Yan-Tong,Feng, Xiao-Shan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9
Objective: NF-E2-related factor 2 (Nrf2) is activated in several human malignancies. However, the role of Nrf2 in gastric cancer (GC) remains incompletely understood. In this study, we therefore analyzed associations of Nrf2 expression status with clinical features and chemotherapeutic resistance in GC. Materials and Methods: A total of 186 samples from GC patients who underwent gastrectomy were used for prognostic assessment. A further 142 samples from GC cases who received first-line combination chemotherapy were applied for investigation of chemoresistance. The Nrf2 expression was evaluated by immunohistochemistry in GC samples, and its relationship with clinicopathological parameters and chemotherapy sensitivity was analyzed. The effect of Nrf2 gene silencing on chemotherapy resistance was also examined by cell viability assay in vivo. Results: Of the 186 patients with GC, 104/186 (55.9%) showed high expression for Nrf2. The overexpression of Nrf2 was an independent predictor of overall survival [OS, hazard ratio (HR) 3.9; P=0.011] and disease-free survival (DFS, HR 4.3; P=0.002). The gene silencing of Nrf2 reduced resistance to cell death induced by 5-FU in GC cell lines. Conclusion: Our data show that Nrf2 is an independent prognostic factor in GC. Furthermore, Nrf2 confers resistance to chemotherapeutic drug 5-FU in GC cells. Taken together, Nrf2 is a potential prognostic marker and predictive for 5-FU resistance in GC.
( Xinli Hu ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2
Piles have been widely used to stabilize landslides in reservoir area. The interaction between stabilizing piles and landslide body is complicated and is vital for evaluating the long-term safety of landslides and reservoirs. Taking the Majiagou landslide in Hubei Province, China, as a prototype, two physical models with and without piles were constructed with a geometrical similarity ratio of 1:40. The water level in the models was raised and maintained to an elevation of 0.89 m. The deformation, earth pressure, and pore-water pressure of the landslide and the strain of one representative pile were recorded during the tests. The comparison between the model with piles and that without piles shows that: (1) Piles significantly improved the deformation resistance of landslides. Landslides with piles can tolerate a larger deformation before failure and the displacement rate of landslides after failure was reduced; (2) The implantation of piles changed the soil pressure distribution of landslides. The soil pressures at the upslope and around the piles increased while those at the downslope decreased. The distribution of soil pressures along the depth at the uphill and downhill side of the piles changed from triangular to invert triangular and parabolic, respectively; (3) Piles arrested the anticipant slip surface that occurred in an unreinforced landslide, and at least two sliding bands traversed the landslide. (4) Comparison of the pile-reinforced landslide model with those in literature with piles with a much higher stiffness show that the stiffness of piles significantly affects the mechanical interaction between piles and landslides.
Xin Zhao,Fangchao Cheng,Yingcheng Hu 한국섬유공학회 2021 Fibers and polymers Vol.22 No.1
Cellulose nanofibrils (CNFs) were successfully isolated from agro-industrial waste (cornstalk, corn flesh, andcorncob) by subjecting the raw materials to organosolv and peroxide treatment, followed by ultrasonication. A detailedcomparative study was performed. Characterization results showed that the CNFs from cornstalk (CS) exhibited higher yieldand lignin content (20.81 %), compared with CNFs from corn flesh (CF) and corncob (CC). The CNFs from CF and CCexhibited similar morphology, particle size, crystallinity, and thermal stability but showed improved ultraviolet blockingability and optical transparency relative to those of CS. The CNFs from CF showed higher dispersion stability andmechanical properties than those from CS and CC. Peroxide treatment negatively influenced crystallinity and thermalstability, but exerted no apparent effect on optical transparency and mechanical strength. Thus, this study demonstrates thatagro-industrial wastes are sustainable resources for CNF production, which can potentially have a wide range of value-addedapplications. Ionic liquid-aided solvothermal treatment followed by ultrasonication is a facile and ideal method to produceCNFs with ultraviolet blocking ability.