論中國傳統企業效率問題

康 埈 荣,张守鑫 韓國外國語大學校 外國學綜合硏究센터 中國硏究所 2005 中國硏究 Vol.35 No.-

Numerical investigation on the wind stability of super long-span partially earth-anchored cable-stayed bridges

Xin-jun Zhang,Mei Yao 한국풍공학회 2015 Wind and Structures, An International Journal (WAS Vol.21 No.4

To explore the favorable structural system of cable-stayed bridges with ultra-kilometer main span, based on a fully self-anchored cable-stayed bridge with 1400 m main span, a partially earth-anchored cable-stayed bridge scheme with the same main span is designed. Numerical investigation on the dynamic characteristics, aerostatic and aerodynamic stability of both two bridge schemes is conducted, and the results are compared to those of a suspension bridge with similar main span, and considering from the aspect of wind stability, the feasibility of using partially earth-anchored cable-stayed bridge in super long-span bridges with ultra-kilometer main span is discussed. Moreover, the effects of structural design parameters including the length of earth-anchored girder, the number of auxiliary piers in side span, the height and width of girder, the tower height etc on the dynamic characteristics, aerostatic and aerodynamic stability of a partially earth-anchored cable-stayed bridge are analyzed, and their reasonable values are proposed. The results show that as compared to fully self-anchored cable-stayed bridge and suspension bridge with similar main span, the partially earth-anchored cable-stayed bridge has greater structural stiffness and better aerostatic and aerodynamic stability, and consequently becomes a favorable structural system for super long-span bridges with ultra-kilometer main span. The partially earth-anchored cable-stayed bridge can achieve greater stiffness and better wind stability under the cases of increasing the earth-anchored girder length, increasing the height and width of girder, setting several auxiliary piers in side span and increasing the tower height.

Spatial analysis of tuberculosis treatment outcomes in Shanghai: implications for tuberculosis control

Zhang Jing,Shen Xin,Yang Chongguang,Chen Yue,Guo Juntao,Wang Decheng,Zhang Jun,Lynn Henry,Hu Yi,Pan Qichao,Zhang Zhijie 한국역학회 2022 Epidemiology and Health Vol.44 No.-

OBJECTIVES: Tuberculosis (TB) treatment outcomes are a key indicator in the assessment of TB control programs. We aimed to identify spatial factors associated with TB treatment outcomes, and to provide additional insights into TB control from a geographical perspective.METHODS: We collected data from the electronic TB surveillance system in Shanghai, China and included pulmonary TB patients registered from January 1, 2009 to December 31, 2016. We examined the associations of physical accessibility to hospitals, an autoregression term, and random hospital effects with treatment outcomes in logistic regression models after adjusting for demographic, clinical, and treatment factors.RESULTS: Of the 53,475 pulmonary TB patients, 49,002 (91.6%) had successful treatment outcomes. The success rate increased from 89.3% in 2009 to 94.4% in 2016. The successful treatment outcome rate varied among hospitals from 78.6% to 97.8%, and there were 12 spatial clusters of poor treatment outcomes during the 8-year study period. The best-fit model incorporated spatial factors. Both the random hospital effects and autoregression terms had significant impacts on TB treatment outcomes, ranking 6th and 10th, respectively, in terms of statistical importance among 14 factors. The number of bus stations around the home was the least important variable in the model.CONCLUSIONS: Spatial autocorrelation and hospital effects were associated with TB treatment outcomes in Shanghai. In highly-integrated cities like Shanghai, physical accessibility was not related to treatment outcomes. Governments need to pay more attention to the mobility of patients and different success rates of treatment among hospitals.

Wind stability of a structurally non-symmetric suspension bridge under erection

Xin-Jun Zhang 한국풍공학회 2009 Wind and Structures, An International Journal (WAS Vol.12 No.5

Study of seismic performance and favorable structural system of suspension bridges

Xin-Jun Zhang,Chao Zhang 국제구조공학회 2016 Structural Engineering and Mechanics, An Int'l Jou Vol.60 No.4

By taking the Runyang Highway Bridge over the Yangtze River with 1490 m main span as example, structural response of the bridge under the horizontal and vertical seismic excitations is investigated by the response spectrum and time-history analysis of MIDAS/Civil software respectively, the seismic behavior and the influence of structural nonlinearity on the seismic response of the bridge are revealed. Considering the aspect of seismic performance, the suitability of employing the suspension bridge in super long-span bridges is investigated as compared to the cable-stayed bridge and cable-stayed-suspension hybrid bridge with the similar main span. Furthermore, the effects of structural parameters including the span arrangement, the cable sag to span ratio, the side to main span ratio, the girder height, the central buckle and the girder support system etc on the seismic performance of the bridge are investigated by the seismic response spectrum analysis, and the favorable earthquake-resistant structural system of suspension bridges is also discussed.

Study of structural parameters on the aerodynamic stability of three-tower suspension bridge

Zhang, Xin-Jun Techno-Press 2010 Wind and Structures, An International Journal (WAS Vol.13 No.5

In comparison with the common two-tower suspension bridge, due to the lack of effective longitudinal restraint of the center tower, the three-tower suspension bridge becomes a structural system with greater flexibility, and more susceptible to the wind action. By taking a three-tower suspension bridge-the Taizhou Bridge over the Yangtze River with two main spans of 1080 m as example, effects of structural parameters including the cable sag to span ratio, the side to main span ratio, the deck's dead load, the deck's bearing system, longitudinal structural form of the center tower and the cable system on the aerodynamic stability of the bridge are investigated numerically by 3D nonlinear aerodynamic stability analysis, the favorable structural system of three-tower suspension bridge with good wind stability is discussed. The results show that good aerodynamic stability can be obtained for three-tower suspension bridge as the cable sag to span ratio is assumed ranging from 1/10 to 1/11, the central buckle are provided between main cables and the deck at midpoint of main spans, the longitudinal bending stiffness of the center tower is strengthened, and the spatial cable system or double cable system is employed.

Investigation on mechanics performance of cable-stayed-suspension hybrid bridges

Xin-Jun Zhang 한국풍공학회 2007 Wind and Structures, An International Journal (WAS Vol.10 No.6

The cable-stayed-suspension hybrid bridge is a cooperative system of the cable-stayed bridge and suspension bridge, and takes some advantages and also makes up some deficiencies of both the two bridge systems, and therefore becomes strong in spanning. By taking the cable-stayed-suspension hybrid bridge, suspension bridge and cable-stayed bridge with main span of 1400 m as examples, the mechanics performance including the static and dynamic characteristics, the aerostatic and aerodynamic stability etc is investigated by 3D nonlinear analysis. The results show that as compared to the suspension bridge and cable-stayed bridge, the cable-stayed-suspension hybrid bridge has greater structural stiffness, less internal forces and better wind stability, and is favorable to be used in super long-span bridges.

Exploration of Molecular Mechanisms of Diffuse Large B-cell Lymphoma Development Using a Microarray

Zhang, Zong-Xin,Shen, Cui-Fen,Zou, Wei-Hua,Shou, Li-Hong,Zhang, Hui-Ying,Jin, Wen-Jun Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Objective: We aimed to identify key genes, pathways and function modules in the development of diffuse large B-cell lymphoma (DLBCL) with microarray data and interaction network analysis. Methods: Microarray data sets for 7 DLBCL samples and 7 normal controls was downloaded from the Gene Expression Omnibus (GEO) database and differentially expressed genes (DEGs) were identified with Student's t-test. KEGG functional enrichment analysis was performed to uncover their biological functions. Three global networks were established for immune system, signaling molecules and interactions and cancer genes. The DEGs were compared with the networks to observe their distributions and determine important key genes, pathways and modules. Results: A total of 945 DEGs were obtained, 272 up-regulated and 673 down-regulated. KEGG analysis revealed that two groups of pathways were significantly enriched: immune function and signaling molecules and interactions. Following interaction network analysis further confirmed the association of DEGs in immune system, signaling molecules and interactions and cancer genes. Conclusions: Our study could systemically characterize gene expression changes in DLBCL with microarray technology. A range of key genes, pathways and function modules were revealed. Utility in diagnosis and treatment may be expected with further focused research.

Protective effects of phillyrin against influenza A virus in vivo

Xin-yan Qu,Qing-jun Li,Hui-min Zhang,Xiao-juan Zhang,Peng-hui Shi,Xiu-juan Zhang,Jing Yang,Zhe Zhou,Sheng-qi Wang 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.7

Influenza A virus infection represents a great threat to public health. However, owing to side effects and the emergence of resistant virus strains, the use of currently available anti-influenza drugs may be limited. In order to identify novel anti-influenza drugs, we investigated the antiviral effects of phillyrin against influenza A virus infection in vivo. The mean survival time, lung index, viral titers, influenza hemagglutinin (HA) protein and serum cytokines levels, and histopathological changes in lung tissue were examined. Administration of phillyrin at a dose of 20 mg/kg/day for 3 days significantly prolonged the mean survival time, reduced the lung index, decreased the virus titers and interleukin-6 levels, reduced the expression of HA, and attenuated lung tissue damage in mice infected with influenza A virus. Taken together, these data showed that phillyrin had potential protective effects against infection caused by influenza A virus.

Mechanics feasibility of using CFRP cables in super long-span cable-stayed bridges

Zhang, Xin-Jun Techno-Press 2008 Structural Engineering and Mechanics, An Int'l Jou Vol.29 No.5

To gain understanding of the applicability of CFRP cables in super long-span cable-stayed bridges, by taking a 1400 m cable-stayed bridge as example, mechanics performance including the static behavior under service load, dynamic behavior, wind stability and seismic behavior of the bridge using either steel or CFRP cables are investigated numerically and compared. The results show that viewed from the aspect of mechanics performance, the use of CFRP cables in super long-span cable-stayed bridges is feasible, and the cross-sectional areas of CFRP cables should be determined by the principle of equivalent axial stiffness.