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      • KCI등재

        Metalens for improving optical coherence tomography

        Guo Songming,Feng Weibin,Long Yong,Liu Zhihao,Fu Xiao,Liang Haowen,Li Juntao 한국물리학회 2022 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.81 No.1

        Optical coherence tomography is one of the most attractive new tomographic techniques, especially in the detection and imaging of biological tissues. For the detection and imaging of human corneas, the current ultra-high-resolution optical coherence tomography technology faces the challenge that the depth of focus is too short to scan the entire human cornea in a single amplitude scan. Here, we propose and design a silicon metalens to replace the objective lens in the sample arm of the optical coherence tomography system. In our simulation, a uniform focused beam with a depth of focus of 886 μm, an axial resolution of 3.1 μm and a lateral resolution of 2.2 μm can be generated by the metalens, which is under the excitation of broadband Gaussian light with wavelength coverage from 800 to 900 nm. This metalens fully satisfies the depth of focus and resolution requirements of the ultra-high-resolution optical coherence tomography system for human corneas, hence expands the application of optical coherence tomography in medical science for the benefit of mankind.

      • A Chaperone Function of NO CATALASE ACTIVITY1 Is Required to Maintain Catalase Activity and for Multiple Stress Responses in Arabidopsis

        Li, Jing,Liu, Juntao,Wang, Guoqiang,Cha, Joon-Yung,Li, Guannan,Chen, She,Li, Zhen,Guo, Jinghua,Zhang, Caiguo,Yang, Yongqing,Kim, Woe-Yeon,Yun, Dae-Jin,Schumaker, Karen S.,Chen, Zhongzhou,Guo, Yan American Society of Plant Biologists 2015 The Plant cell Vol.27 No.3

        <P>Arabidopsis protein NCA1 interacts with catalases in the cytosol and increases catalase activity through maintaining catalase folding state, which is required for stress responses.</P><P>Catalases are key regulators of reactive oxygen species homeostasis in plant cells. However, the regulation of catalase activity is not well understood. In this study, we isolated an <I>Arabidopsis thaliana</I> mutant, <I>no catalase activity1-3</I> (<I>nca1-3</I>) that is hypersensitive to many abiotic stress treatments. The mutated gene was identified by map-based cloning as NCA1, which encodes a protein containing an N-terminal RING-finger domain and a C-terminal tetratricopeptide repeat-like helical domain. NCA1 interacts with and increases catalase activity maximally in a 240-kD complex in planta. In vitro, NCA1 interacts with CATALASE2 (CAT2) in a 1:1 molar ratio, and the NCA1 C terminus is essential for this interaction. CAT2 activity increased 10-fold in the presence of NCA1, and zinc ion binding of the NCA1 N terminus is required for this increase. NCA1 has chaperone protein activity that may maintain the folding of catalase in a functional state. NCA1 is a cytosol-located protein. Expression of <I>NCA1</I> in the mitochondrion of the <I>nca1-3</I> mutant does not rescue the abiotic stress phenotypes of the mutant, while expression in the cytosol or peroxisome does. Our results suggest that NCA1 is essential for catalase activity.</P>

      • KCI등재

        Effect of La2O3 promoter on NiO/Al2O3 catalyst in CO methanation

        Hongyun Qin,Cuili Guo,Yuanyuan Wu,Juntao Zhang 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.7

        A series of NiO/Al2O3 catalysts promoted by different La2O3 contents were prepared by impregnation method. The physicochemical properties of NiO-La2O3/Al2O3 were characterized by N2 adsorption-desorption, X-ray diffraction(XRD), H2 temperature programmed reduction (H2-TPR) and H2 chemisorption. The effect of La2O3 on the activityof NiO/Al2O3 for CO methanation was investigated in a fixed bed reactor. A lifetime test, as well as thermogravimetric(TG) analysis, was performed to investigate the stability performance and anti-carbon deposition of catalysts. Theresults showed that the addition of La2O3 can restrain the growth of NiO particles, increase the H2 uptake and Ni dispersion,and therefore enhance the activity of catalysts. When the La2O3 content was 3 wt%, a CO conversion of 98%and a selectivity to CH4 of 96% were obtained at 400 oC. Furthermore, the catalyst NiO-La2O3/Al2O3 with 3 wt% La2O3content displayed highly stable performance in long-term tests, especially exhibiting good anti-carbon deposition property.

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        Spatial analysis of tuberculosis treatment outcomes in Shanghai: implications for tuberculosis control

        Zhang Jing,Shen Xin,Yang Chongguang,Chen Yue,Guo Juntao,Wang Decheng,Zhang Jun,Lynn Henry,Hu Yi,Pan Qichao,Zhang Zhijie 한국역학회 2022 Epidemiology and Health Vol.44 No.-

        OBJECTIVES: Tuberculosis (TB) treatment outcomes are a key indicator in the assessment of TB control programs. We aimed to identify spatial factors associated with TB treatment outcomes, and to provide additional insights into TB control from a geographical perspective.METHODS: We collected data from the electronic TB surveillance system in Shanghai, China and included pulmonary TB patients registered from January 1, 2009 to December 31, 2016. We examined the associations of physical accessibility to hospitals, an autoregression term, and random hospital effects with treatment outcomes in logistic regression models after adjusting for demographic, clinical, and treatment factors.RESULTS: Of the 53,475 pulmonary TB patients, 49,002 (91.6%) had successful treatment outcomes. The success rate increased from 89.3% in 2009 to 94.4% in 2016. The successful treatment outcome rate varied among hospitals from 78.6% to 97.8%, and there were 12 spatial clusters of poor treatment outcomes during the 8-year study period. The best-fit model incorporated spatial factors. Both the random hospital effects and autoregression terms had significant impacts on TB treatment outcomes, ranking 6th and 10th, respectively, in terms of statistical importance among 14 factors. The number of bus stations around the home was the least important variable in the model.CONCLUSIONS: Spatial autocorrelation and hospital effects were associated with TB treatment outcomes in Shanghai. In highly-integrated cities like Shanghai, physical accessibility was not related to treatment outcomes. Governments need to pay more attention to the mobility of patients and different success rates of treatment among hospitals.

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