Effective 3-D FEM for large-scale high temperature superconducting racetrack coil

Xiangyu Huang,Zhen Huang,Xiaoyong Xu,Wan Li,Zhijian Jin 한국초전도.저온공학회 2019 한국초전도저온공학회논문지 Vol.21 No.3

In various types of large-scale electrical applications, the number of coil turns in such machines is usually large. Electromagnetic simulation of large-scale superconducting coils (tens to hundreds of turns) is indispensable in the design process of superconducting electrical equipment. However, due to the large scale of the coil and the large aspect ratio of super-conducting material layer in HTS coated conductor, it is usually difficult or even unable to perform 3-D transient electromagnetic simulation. This paper introduces an effective 3-D electromagnetic simulation method for large-scale HTS coated conductor coil based on T-A formulation. The simulation and experimental results show that the 3-D model based on the T-A formulation using homogeneous strategy is more accurate than the traditional 2-D models. The memory usage is not sensitive to the number of turns and this model will be even more superior as the number of turns becomes larger.

Rehmannioside D mitigates disease progression in rats with experimental-induced diminished ovarian reserve via Forkhead Box O1/KLOTHO axis

Yan Liang,Huimin Wang,Jin Chen,Lingyan Chen,Xiaoyong Chen 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.2

This study aims to explore the impact of Rehmannioside D (RD) on ovarian functions of rats with diminished ovarian reserve (DOR) and its underlying mechanisms of action. A single injection of cyclophosphamide was performed to establish a DOR rat model, and fourteen days after the injection, the rats were intragastrically administrated with RD for two weeks. Rat estrus cycles were tested using vaginal smears. Ovarian tissues were histologically evaluated, the number of primordial, mature, and atretic follicles was calculated, and the apoptotic rate of granulosa cells. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) levels were determined by ELISA assays. Protein levels of Forkhead Box O1 (FOXO1), KLOTHO, Bcl-2, and Bax were investigated in ovarian tissues of DOR rats. The binding between FOXO1 and KLOTHO was verified by ChIP assay. High-dose administration of RD into DOR rats improved their estrus cycles, increased ovarian index, enhanced the number of primordial and mature follicles, reduced the number of atretic follicle number, and ovarian granulosa cell apoptosis in addition to inhibiting FSH and LH levels and upregulating E2 expression. FOXO1 and KLOTHO were significantly suppressed in DOR rats. FOXO1 knockdown partially suppressed the protective effects of RD on DOR rats, and KLOTHO overexpression could restore RD-induced blockade of DOR development despite knocking down FOXO1. FOXO1 antibody enriched KLOTHO promoter, and the binding between them was reduced in DOR group compared to that in sham group. RD improved ovarian functions in DOR rats and diminished granulosa cell apoptosis via the FOXO1/KLOTHO axis

Fast iterative algorithm for calculating the critical current of second generation high temperature superconducting racetrack coils

Xiangyu Huang,Zhen Huang,Xiaoyong Xu,Wan Li,Zhijian Jin 한국초전도.저온공학회 2019 한국초전도저온공학회논문지 Vol.21 No.4

The critical current is one of the key parameters of high temperature superconducting (HTS) racetrack coils. Therefore, it is significant to calculate critical currents of HTS coils. This paper introduces a fast iterative algorithm for calculating the critical current of second generation (2G) HTS coils. This model does not need to solve long charging transients which greatly reduced the amount of calculation. To validate this model, the V-I curve of four 2G HTS double racetrack coils are measured. The effect of the silicon steel sheet on the critical current of the racetrack coil is also studied based on this algorithm.

Fast iterative algorithm for calculating the critical current of second generation high temperature superconducting racetrack coils

Huang, Xiangyu,Huang, Zhen,Xu, Xiaoyong,Li, Wan,Jin, Zhijian The Korea Institute of Applied Superconductivity a 2019 한국초전도저온공학회논문지 Vol.21 No.4

The critical current is one of the key parameters of high temperature superconducting (HTS) racetrack coils. Therefore, it is significant to calculate critical currents of HTS coils. This paper introduces a fast iterative algorithm for calculating the critical current of second generation (2G) HTS coils. This model does not need to solve long charging transients which greatly reduced the amount of calculation. To validate this model, the V-I curve of four 2G HTS double racetrack coils are measured. The effect of the silicon steel sheet on the critical current of the racetrack coil is also studied based on this algorithm.

Effective 3-D FEM for large-scale high temperature superconducting racetrack coil

Huang, Xiangyu,Huang, Zhen,Xu, Xiaoyong,Li, Wan,Jin, Zhijian The Korea Institute of Applied Superconductivity a 2019 한국초전도저온공학회논문지 Vol.21 No.3

In various types of large-scale electrical applications, the number of coil turns in such machines is usually large. Electromagnetic simulation of large-scale superconducting coils (tens to hundreds of turns) is indispensable in the design process of superconducting electrical equipment. However, due to the large scale of the coil and the large aspect ratio of super-conducting material layer in HTS coated conductor, it is usually difficult or even unable to perform 3-D transient electromagnetic simulation. This paper introduces an effective 3-D electromagnetic simulation method for large-scale HTS coated conductor coil based on T-A formulation. The simulation and experimental results show that the 3-D model based on the T-A formulation using homogeneous strategy is more accurate than the traditional 2-D models. The memory usage is not sensitive to the number of turns and this model will be even more superior as the number of turns becomes larger.

Genome-wide analyses and expression patterns under abiotic stress of LAC gene family in pear (Pyrus bretschneideri)

Lu Chunyi,Yang Tianyuan,Zhang Yiwu,Miao Xingchen,Jin Cong,Xu Xiaoyong 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.3

Plant laccases are copper-containing glycoproteins oxidizing monolignol, which is a key regulator for lignin polymerization and deposition in plant cell walls. In plants, the LAC gene family has been identifed and functionally characterized in Arabi�dopsis, rice, and other plant species. Whereas, no systematic analysis of LAC genes was explored in pear (Pyrus bretschnei�deri), especially their biological roles in stress responses. In this study, a total of 40 P. bretschneideri LACs (PbLACs) were identifed from the pear genome, among which 32 PbLACs members were distributed on 14 chromosomes, and 8 PbLACs were mapped onto scafold contigs. Subsequently, the chromosome localizations, gene structures, conserved domains, gene duplication were analyzed comprehensively and bioinformatically. Phylogenetic analysis demonstrated that the PbLACs were classifed into seven groups. Synteny analysis exhibited that whole-genome duplication (WGD)/segmental duplication was essential for the expansion of PbLAC family. In detail, the 26 PbLACs duplicated gene pairs were taken place at the two WGD events. Further, our results showed that purifying selection presented as the primary force to drive the evolution of PbLACs. Notably, the transcriptomic data were used for exploring the biological roles of PbLACs in response to abiotic stresses (cold, drought, and salt) in pear. We found that the expression of certain PbLACs was signifcantly induced by drought, cold or salt treatments, suggesting that these PbLACs are potentially key genes for further functional characterization in pear in the future. Taken together, our results not only contribute to an enhanced understanding of the evolutional complexity of PbLAC gene family but also provide a good platform for functional studies of PbLAC genes in response to various abiotic stresses.

Study on Mud-Water Separation Test Technology for Shield Slurry in Underground Tunnel

( Changhong Yan ),( Shulan Guo ),( Liang Wen ),( Liangwei Li ),( Xiaoyong Yang ),( Zhiwei Jin ),( Xuyang Fan ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

The construction of urban subway produced a large amount of slurry with hign moisture content. In order to ensure the stability of the excavation face during the construction of the tunnel shield, prevent the spoil from adhering to the shield cutter, a large amount of additives such as water, bentonite, foaming agent are added to the spoil. Therefore, the slurry has the characteristics of uneven particle composition, high moisture content, low permeability and remarkable plastic flow, and its shear strength is almost zero. The transportation and stacking of slurry can cause environmental pollution and damage the ecological environment. To solve this problem, our research team developed a set of mud-water separation test device to carry out research on mud-water separation technology. The Optimal treatment plan for mud-water separation is given by a large number of laboratory tests: when the moisture content of slurry is relatively high, the vacuum negative pressur is firstly used to discharge the free water. When the moisture content drops below the liquid limit, the electroosmosis and the vacuum negative pressure are combined to discharge the bound water, at which time the moisture content in the slurry is close to the plastic limit, thereby achieving slurry hardening. This method has a fast drainage speed and low cost, and has been successfully applied to the Suzhou Metro. It is not only conducive to the resource utilization of slurry, but more importantly, it can effectively protect the ecological environment.

Mutations of ARX and non-syndromic intellectual disability in Chinese population

Yufei Wu,Huan Zhang,Xiaofen Liu,Zhangyan Shi,Hongling Li,Zhibin Wang,Xiaoyong Jie,Shao-Ping Huang,Fu-Chang Zhang,Junlin Li,Ke-Jin Zhang,Xiao-Cai Gao 한국유전학회 2019 Genes & Genomics Vol.41 No.1

Mutations of Aristaless-related homeobox (ARX) gene were looked as the third cause of non-syndromic intellectual disability (NSID), while the boundary between true disease-causing mutations and non-disease-causing variants within this gene remains elusive. To investigate the relationship between ARX mutations and NSID, a panel comprising six reported causal mutations of the ARX was detected in 369 sporadic NSID patients and 550 random participants in Chinese. Two mutations, c.428_451 dup and p.G286S, may be disease-causing mutations for NSID, while p.Q163R and p.P353L showed a great predictive value in female NSID diagnosis with significant associations (X2 = 19.60, p = 9.54e−6 for p.Q163R; X2 = 25.70, p = 4.00e−07 for p.P353L), carriers of these mutations had an increased risk of NSID of more than fourfold. Detection of this panel also predicted significant associations between genetic variants of the ARX gene and NSID (p = 3.73e−4). The present study emphasized the higher genetic burden of the ARX gene on NSID in the Chinese population, molecular analysis of this gene should be considered for patients presenting NSID of unknown etiology.

Construction of Phenol/O2 Fuel Cell with CuO/MWCNTs Modified Electrode as Anode

Shuhui Liu,Yuan Wu,Yonglei Xing,Yan Hai,Juan Peng,Gang Ni,Xiaoyong Jin 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.10

Traditional biofuel cells (BFCs) are devices that use biological catalysts to catalyze the oxidation of organic materials and in the meantime convert chemical energy into electrical energy. In this work, a nonenzymatic catalyst that integrated copper oxide with multi-walled carbon nanotubes (CuO/MWCNTs) was synthesized by a simple solvothermal method, and the composites show an outstanding electrocatalytic activity for oxidation of phenol due to the synergistical contribution of CuO nanoparticles and MWCNTs. The effects of the pH, concentration of electrolyte and phenol and scan rate on the phenol oxidation are investigated. Benefitting from the excellent performance toward phenol oxidation, a H-type phenol fuel cell was fabricated with CuO/MWCNTs as anode material and electro-deposited platinum film as cathode material. The results show that the phenol fuel cell has an open-circuit potential (OCP) of 0.69 V and can produce a maximum power density of 0.25 mW · cm -2 at 0.44 V with 500 mg · L -1 phenol and 0.1 mol · L -1 PBS. The stability test revealed that the fuel cell could still deliver about 0.24 mW · cm -2 after repeating the test for five times, indicating that the fuel cell has good stability.