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RISS 인기검색어
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- 저자 : Xianwen Chen (검색결과 5 건)
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Lin, Jing,Li, Xican,Chen, Li,Lu, Weizhao,Chen, Xianwen,Han, Lu,Chen, Dongfeng Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.6
[6]-Gingerol is known as the major bioactive constituent of ginger. In the study, it was observed to effectively protect against ${\bullet}OH$-induced DNA damage ($IC_{50}$ $328.60{\pm}24.41{\mu}M$). Antioxidant assays indicated that [6]-gingerol could efficiently scavenge various free radicals, including ${\bullet}OH$ radical ($IC_{50}$ $70.39{\pm}1.23{\mu}M$), ${\bullet}O_2{^-}$ radical ($IC_{50}$ $228.40{\pm}9.20{\mu}M$), $DPPH{\bullet}$radical ($IC_{50}$ $27.35{\pm}1.44{\mu}M$), and $ABTS{^+}{\bullet}$radical ($IC_{50}$ $2.53{\pm}0.070{\mu}M$), and reduce $Cu^{2+}$ ion ($IC_{50}$ $11.97{\pm}0.68{\mu}M$). In order to investigate the possible mechanism, the reaction product of [6]-gingerol and $DPPH{\bullet}$ radical was further measured using HPLC combined mass spectrometry. The product showed a molecular ion peak at m/z 316 $[M+Na]^+$, and diagnostic fragment loss (m/z 28) for quinone. On this basis, it can be concluded that: (i) [6]-gingerol can effectively protect against ${\bullet}OH$-induced DNA damage; (ii) a possible mechanism for [6]-gingerol to protect against oxidative damage is ${\bullet}OH$ radical scavenging; (iii) [6]-gingerol scavenges ${\bullet}OH$ radical through hydrogen atom ($H{\bullet}$) transfer (HAT) and sequential electron (e) proton transfer (SEPT) mechanisms; and (iv) both mechanisms make [6]-gingerol be oxidized to semi-quinone or quinone forms.
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Jing Lin,Xican Li,Li Chen,Weizhao Lu,Xianwen Chen,Lu Han,Dongfeng Chen 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.6
[6]-Gingerol is known as the major bioactive constituent of ginger. In the study, it was observed to effectively protect against •OH-induced DNA damage (IC50 328.60 ± 24.41 μM). Antioxidant assays indicated that [6]- gingerol could efficiently scavenge various free radicals, including •OH radical (IC50 70.39 ± 1.23 μM), •O2 − radical (IC50 228.40 ± 9.20 μM), DPPH• radical (IC50 27.35 ± 1.44 μM), and ABTS+• radical (IC50 2.53 ± 0.070 μM), and reduce Cu2+ ion (IC50 11.97 ± 0.68 μM). In order to investigate the possible mechanism, the reaction product of [6]-gingerol and DPPH• radical was further measured using HPLC combined mass spectrometry. The product showed a molecular ion peak at m/z 316 [M+Na]+, and diagnostic fragment loss (m/z 28) for quinone. On this basis, it can be concluded that: (i) [6]-gingerol can effectively protect against •OH-induced DNA damage; (ii) a possible mechanism for [6]-gingerol to protect against oxidative damage is •OH radical scavenging; (iii) [6]-gingerol scavenges •OH radical through hydrogen atom (H•) transfer (HAT) and sequential electron (e) proton transfer (SEPT) mechanisms; and (iv) both mechanisms make [6]-gingerol be oxidized to semi-quinone or quinone forms.
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Xiaoxia Chen,Wuhui Lin,Xianwen He,Liangliang Feng,Kuo-Ying Wang 한국기상학회 2022 Asia-Pacific Journal of Atmospheric Sciences Vol.58 No.1
The Arctic Oscillation (AO) accounts for a large fraction of recent decadal climate trends in Northern Hemisphere (NH) high latitudes. In East Asia, an elevated AO index (AOI) was associated with warmer temperatures in middle- to high-latitude regions, colder temperatures over low-latitude regions, and elevated ozone intrusion from the stratosphere. Elevated beryllium-7 (7Be) is produced in the stratosphere. Few studies have discussed the relationship between 7Be and the AO. Here, we identify the AO signature in 7Be and lead (Pb)-210 observed at a tropical ambient monitoring site in Nanning (22.8°N, 108.5°E) during the December 2014–December 2017 period. Our results show that the 7Be and 210Pb concentrations are positively and significantly correlated with the AOI (P < 0.01). These results show that elevated 7Be and 210Pb are associated with an increase in the AOI, reflecting air masses originating from NH high latitudes and vertically from the high-latitude upper troposphere and lower stratosphere regions to tropical latitudes in East Asia. These results have been verified with ozonesonde data without seasonality and with two meteorological data sets. Our results are also confirmed by observational data over the Pacific regions. We conclude that the AO exerts impacts over the tropical regions in East Asia, and 7Be can be used as a tracer to track the impacts of the AO.
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Le Song,Qin Ouyang,Xianwen Huang,Hongbo Ma,Peng Chen,Lanping Shen,Xuan Wang 한국섬유공학회 2021 Fibers and polymers Vol.22 No.1
Lignin/polyacrylonitrile (PAN) composite precursors and PAN precursors were prepared by wet spinning and thenconverted into carbon fibers together under different carbonization temperatures. The microscopic morphology, mechanicalproperties and microstructure of the carbon fibers were studied. All the carbon fibers had dense structure without any visiblemacrovoids. Carbon fibers with tensile strength of 2.1 GPa and tensile modulus of 224 GPa were obtained from the lignin/PAN composite precursor by carbonizing at 1200 oC. Interestingly, the lignin/PAN-based carbon fibers had a unique uniformdisordered carbon structure. They were expected to be applied in the fields of electrothermal conversion and thermalinsulation, besides composites.
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Zhang Hongxing,Mi Min,Miao Jianyin,Wang Lu,Chen Yang,Ding Ting,Ning Xianwen,Huo Yuhua 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.6
This paper describes the development and result of ground experiment and analyzes the on-orbit operation of Loop heat pipes (LHP) for the Chinese circumlunar return and reentry spacecraft. A novel LHP was developed to satisfy the thermal control requirements of Inertial measurement units (IMU). The LHP consisted of an integrated evaporator subassembly, a cambered condenser, and an electric explosion valve. Ground experiments were conducted to investigate the startup characteristics, and heat transfer and heat insulation performance of the LHPs. During a flight mission, the LHPs work as a thermal switch and perform both heat transfer and insulation functions. Before returning to the earth’s atmosphere, the valves of the reentry capsule are opened to discharge working fluid and prevent heat transfer from the capsule wall to the devices. In the flight mission, the LHPs performed all the required functions, and the IMU temperatures were maintained within an allowable range.
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