High Performance De-interlacing Algorithm Based on Region Adaptive Interpolation Filter

Yang, Yang,Chen, Xiangdong,Wang, Jin,Jeong, Jechang 한국방송·미디어공학회 2011 한국방송공학회 학술발표대회 논문집 Vol.2011 No.11

In order to convert interlaced video into progressive scanning format, this paper proposed a high performance de-interlacing algorithm based on region adaptive interpolation filter design. Specifically, usage of the 6-tap filter is only for the most complex region, but for the smooth and regular edge region, much more correlated filter such as 2-tap or 4-tap filter should be used instead. According to the experimental results, the proposed algorithm has achieved noticeably good performance.

Network Security Threats Situation Assessment and Analysis Technology Study

Xiangdong Cai,Yang Jingyi,Huanyu Zhang 보안공학연구지원센터 2013 International Journal of Security and Its Applicat Vol.7 No.5

A Review of Sustainable Network Design for Road Networks

Xiangdong Xu,안토니첸,Chao Yang 대한토목학회 2016 KSCE JOURNAL OF CIVIL ENGINEERING Vol.20 No.3

The Network Design Problem (NDP) is a strategical decision-making problem in planning, designing, and managing road networks with the aim to make efficient use of limited resources for optimizing the road network performance. Sustainability development is a major concern of various social-economic systems throughout the world. As a critical component of sustainable development, transportation systems should be designed to make positive contributions to the economic, environmental, and social sustainability of the served regions and communities. This requirement significantly uplifts the challenges on the modeling and the analysis of NDP. In this paper, we provide a review on the sustainable road NDP. Specifically, an overview on the three dimensions of sustainable development (i.e., economic, environmental, and social) is first provided, focusing on their representative performance measures relevant to road NDP. Then, we review the existing studies with the classification system of economy and environmentoriented sustainable NDP, economy and equity-oriented sustainable NDP, and three-dimensional sustainable NDP. Future research directions are suggested for advancing the methodological advancement and practical applications of sustainable transportation NDP.

Tissues Expression, Polymorphisms Identification of FcRn Gene and Its Relationship with Serum Classical Swine Fever Virus Antibody Level in Pigs

Liu, Yang,Wang, Chonglong,Liu, Zhengzhu,Xu, Jingen,Fu, Weixuan,Wang, Wenwen,Ding, Xiangdong,Liu, Jianfeng,Zhang, Qin Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.8

Neonatal Fc receptor (FcRn) gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G (IgG) and is responsible for IgG transport and stabilization. In this report, the 8,900 bp porcine FcRn genomic DNA structure was identified and putative FcRn protein included 356 amino acids. Alignment and phylogenetic analysis of the porcine FcRn amino acid sequences with their homologies of other species showed high identity. Tissues expression of FcRn mRNA was detected by real time quantitative polymerase chain reaction (Q-PCR), the results revealed FcRn expressed widely in ten analyzed tissues. One single nucleotide polymorphism (SNP) (HQ026019:g.8526 C>T) in exon6 region of porcine FcRn gene was demonstrated by DNA sequencing analysis. A further analysis of SNP genotypes associated with serum Classical Swine Fever Virus antibody (anti-CSFV) concentration was performed in three pig populations including Large White, Landrace and Songliao Black pig (a Chinese indigenous breed). Our results of statistical analysis showed that the SNP had a highly significant association with the level of anti-CSFV antibody (At d 20; At d 35) in serum (p = 0.008; p = 0.0001). Investigation of expression and polymorphisms of the porcine FcRn gene will help us in further understanding the molecular basis of the antibody regulation pathway in the porcine immune response. All these results indicate that FcRn gene might be regarded as a molecular marker for genetic selection of anti-CSFV antibody level in pig disease resistance breeding programmes.

Tissues Expression, Polymorphisms of IFN Regulatory Factor 6 (IRF6) Gene and Their Associated with Immune Traits in Three Pig Populations

Liu, Yang,Xu, Jingeng,Fu, Weixuan,Weng, Ziqing,Niu, Xiaoyan,Liu, Jianfeng,Ding, Xiangdong,Zhang, Qin Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.2

Interferon regulatory factor 6 (IRF6) gene is a member of the IRF-family, and plays functionally diverse roles in the regulation of the immune system. In this report, the 13,720 bp porcine IRF6 genomic DNA structure was firstly identified with a putative IRF6 protein of 467 amino acids. Alignment and phylogenetic analysis of the porcine IRF6 amino acid sequences with their homologies to other species showed high identity (over 96%). Tissues expression of IRF6 mRNA was observed by RT-PCR, the results revealed IRF6 expressed widely in eight tissues. One SNP (HQ026023:1383 G>C) in exon7 and two SNPs (HQ026023:130 G>A; 232 C>T) in the 5′ promoter region of porcine IRF6 gene were demonstrated by DNA sequencing analysis. A further analysis of SNP genotypes associated with immune traits including IFN-${\gamma}$ and IL10 concentrations in serum was carried out in three pig populations including Large White, Landraces and Songliao Black pig (a Chinese indigenous breed). The results showed that the SNP (HQ026023:1383 G>C) was significantly associated with the level of IFN-${\gamma}$ (d 20) in serum (p = 0.038) and the ratio of IFN-${\gamma}$ to IL10 (d 20) in serum (p = 0.041); The other two SNPs (HQ026023:130 G>A; 232 C>T) were highly significantly associated with IL10 level in serum both at the day 20 (p = 0.005; p = 0.001) and the day 35 (p = 0.004; p = 0.006). Identification of the porcine IRF6 gene will help our further understanding of the molecular basis of the IFN regulation pathway in the porcine immune response. All these results should indicate that the IRF6 gene can be regarded as a molecular marker associated with the IL10 level in serum and used for genetic selection in the pig breeding.

Distributed Adaptive Attitude Tracking of Multiple Spacecraft with a Leader of Nonzero Input

Dapeng Yang,Zhen Chen,Xiangdong Liu 제어·로봇·시스템학회 2013 International Journal of Control, Automation, and Vol.11 No.5

This paper considers the distributed attitude tracking problem of multiple spacecraft with a leader whose control input is possibly nonzero, bounded, and not available to any follower. Based on the relative attitudes and angular velocities of neighboring spacecraft, we design a distributed discon-tinuous adaptive controller to each follower to guarantee that the attitude errors between the followers and the leader converge to zero for any communication graph containing a directed spanning tree with the leader as the root. To tackle the chattering effect caused by the discontinuous controller, we further propose a distributed continuous adaptive controller, under which both the attitude tracking errors and the adaptive gains are ultimately bounded.

Coptis chinensis Polysaccharides Inhibit Advanced Glycation End Product Formation

Ye Yang,Yun Li,Dengke Yin,Song Chen,Xiangdong Gao 한국식품영양과학회 2016 Journal of medicinal food Vol.19 No.6

Coptis chinensis Franch (Huanglian) is commonly used to treat diabetes in China. In this study, the effects of the C. chinensis Franch polysaccharides (CCP) on advanced glycation end product (AGE) formation in vitro and in streptozotocin-induced diabetic mice were investigated. CCP significantly inhibited all the three periods of nonenzymatic protein glycation in vitro, including Amadori product, dicarbonyl compound, and AGE formation (P < .01). In diabetic mice, the administration of CCP not only improved both bodyweight and serum insulin and decreased fasting blood glucose and glycated serum protein concentrations but also decreased the AGE accumulations and morphological abnormalities in pancreas and liver. The inhibitory effects of CCP on AGE formation afford a potential therapeutic use in the prevention and treatment of diabetes.

Chinese Patterns of University-Industry Collaboration

Chen, Xiangdong,Yang, Jian-An,Park, Hyun-Woo Asian Society for Innovation and Policy 2012 Asian Journal of Innovation and Policy Vol.1 No.1

This paper deals with university - industry collaboration movement in China in recent years. By summarizing related development background in Government-Industry-University framework, the paper specifies Chinese pattern through analysis of technology transfer between universities and industries, collaborative R&D between universities and industries in practical fields, and university-run high-tech companies, especially through analysis of joint patenting between universities and their industrial partners in China. The research provides clear picture of Chinese universities' increased development with industrial entities in comprehensive and wider technology fields.

Reliability-based sensitivity of mechanical components with arbitrary distribution parameters

Yimin Zhang,Xiangdong He,Zhou Yang,Qiaoling Liu,Bangchun Wen 대한기계학회 2010 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.24 No.6

This paper presents a reliability-based sensitivity method for mechanical components with arbitrary distribution parameters. Techniques from the perturbation method, the Edgeworth series, the reliability-based design theory, and the sensitivity analysis approach were employed directly to calculate the reliability-based sensitivity of mechanical components on the condition that the first four moments of the original random variables are known. The reliability-based sensitivity information of the mechanical components can be accurately and quickly obtained using a practical computer program. The effects of the design parameters on the reliability of mechanical components were studied. The method presented in this paper provides the theoretic basis for the reliability-based design of mechanical components.

Allergen-Dependent Differences in ILC2s Frequencies in Patients With Allergic Rhinitis

Dachuan Fan,Xiangdong Wang,Min Wang,Yang Wang,Liang Zhang,Ying Li,Erzhong Fan,Feifei Cao,Koen Van Crombruggen,Luo Zhang 대한천식알레르기학회 2016 Allergy, Asthma & Immunology Research Vol.8 No.3

Purpose: Group 2 innate lymphoid cells (ILC2s) are a novel population of lineage-negative cells that induce innate type 2 responses by producing the critical Th2-type cytokines IL-5 and IL-13 in response to IL-25 and IL-33 stimulation. ILC2s accumulation in the peripheral blood of patients with allergic rhinitis (AR) is controversial; the precise role of ILC2s in the immunopathogenesis of AR is still not clear. We investigated the role of ILC2s in phenotypic AR sensitized to distinct allergens. Methods: Flow cytometric analysis of the peripheral blood of 7 healthy controls (HCs), 9 patients monosensitized to house dust mite (HDM), and 8 patients monosensitized to mugwort was performed to quantify ILC2s frequency. Peripheral blood mononuclear cells (PBMCs) were isolated from HDM-AR and mugwort-AR patients, and Lineage- and Lineage+ cells were separated using a fluorescence-activated cell sorter (FACS). IL-5 and IL-13 levels in the supernatants of PBMCs, and Lineage- and Lineage+ cells stimulated with IL-25 and/or IL-33 combined with IL-2 in vitro were assessed using the Milliplex magnetic bead kit. Results: The percentage of ILC2s was significantly elevated in HDM-AR patients compared to mugwort-AR patients and HCs, while no significant difference was found between mugwort-AR patients and HCs. IL-33±IL-25 plus IL-2 induced a significantly greater release of IL-5 and IL-13 in the PBMCs of HDM-AR patients compared to PBMCs of mugwort-AR patients. IL-25 plus IL-2 also induced a significantly greater release of IL-13 in the PBMCs of HDM-AR patients compared to PBMCs of mugwort-AR patients. Stimulation with IL-33 and/or IL-25 combined with IL-2 also induced a significantly greater IL-5 and IL-13 release from Lineage- cells compared to Lineage+ cells. Conclusions: AR patients sensitized to HDM or mugwort allergen have distinct phenotypic and functional profiles in ILC2s frequencies. ILC2s mediate major type 2 immunity in the development of HDM-AR and may be a potential therapeutic target.