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      • KCI등재

        우황청심원(牛黃淸心元)이 저산소증 유발 배양신경세포에 미치는 영향

        조규선,신길조,일수,이원철,정승현,Cho, Gyu-Seon,Shin, Gil-Cho,Moon, Il-Soo,Lee, Won-Chul,Chung, Sung-Hyun 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.2

        Objectives : The purpose of this investigation is to evaluate the effects of Woohwangcheongsim-won on neuronal death of hypoxic E18 cortical neuroblast. Methods : To evaluate the effect of Woohwangcheongsim-won on neuronal death caused by hypoxia, the survival rate of E18 cortical neuroblast was measured with MTT assay and the changes of several synaptic proteins and enzymes were investigated with the immunoblot assays. Results : The E18 cortical neuroblasts were added 50, 100, 500, 1,000, and $5,000{\mu}g/ml$ Woohwangcheongsim-won. They showed neurotoxicity, when the concentration of Woohwangcheongsim-won was above $1,000{\mu}g/ml$. The E18 cortical neuroblasts, which were added 50, 100, and $500{\mu}g/ml$ Woohwangcheongsim-won, were exposed 98% $N_2/5%\;CO_2$ for 3 hours to induce hypoxia, 3 days later, the survival rate of $50{\mu}g/ml$ Woohwangcheongsim-won was 141.5% when compared to the control group. On the immuneblot assays, the expressions of ${\alpha}$CaMKII, NR2A, NR28, PDE2, PSD-95, and eEF-$1{\alpha}$ were increased in normoxia, but those of NR2A, NR2B were decreased in hypoxia when compared to the control group. Conclusions : The data shows that the effects of Woohwangcheongsim-won on neuronal death of hypoxic E18 cortical neuroblast is a significant result.

      • KCI등재
      • KCI등재
      • SCOPUSKCI등재

        우리나라 암환자의 의료기관 접근성의 지역간 불균형

        연옥(Yeon Ok Moon),박은철(Eun Cheol Park),신해림(Hai Rim Shin),원영주(Young Joo Won),정규원(Kyu Won Jung),황순영(Soon Young Hwang),이진희(Jin Hee Lee),공현주(Hyun Joo Kong),황승식(Seung Sik Hwang),이종구(Jong Koo Lee),공인식(In Sik 한국역학회 2006 Epidemiology and Health Vol.28 No.2

          Objectives: To investigate the differences in accessing regional hospitals and the utilization rate of hospitals located in other regions for cancer patients by regions.   Methods: Data for the utilization of regional hospitals for cancer patients were obtained from the Korean National Cancer Incidence Databases in 1999 and 2002. We divided the regions into 16 provinces by administrative districts. We using the SAS 9.1.3 to analyze difference of regional self-sufficiency and the Arcview 3.2 to show in a schematize for regional variation of the regional self-sufficiency.   Results: There were regional variations in the regional self-sufficiency of cancer patients. Especially, Jeollanamdo(1999 13.6%, 2002 12.8%), Gyeongsangbuk-do(1999 22.0%, 2002 20.7%), and Chungcheongnam-do(1999 27.8%, 2002 27.1%) had low regional self-sufficiency. The regional self-sufficiency in Gyeonggi-do and utilization rate of cancer patients who lived in other regions were increased between 1999 and 2002(regional self-sufficiency: 1999 37.2%, 2002 48.2%).   Conclusion: The results of this study showed that there were regional variation in utilization of regional hospitals for cancer patients. Accessibility of cancer patients in metropolitan areas was higher than in small size cities, medium size cities, and rural county areas. These results suggested that it should be considered support medical facilities for cancer patients in rural areas where have lower relevance rate.

      • KCI등재

        BPSK 복조를 위한 K-Band CMOS Four-Port 직접 변환 수신기 설계

        성모(Seong-Mo Moon),박동훈(Donghoon Park),유종원(Jong-Won Yu),이문규(Moon-Que Lee) 한국전자파학회 2010 한국전자파학회논문지 Vol.21 No.2

        본 논문에서는 K-band 응용을 위한 0.18 ㎛ CMOS 공정을 기반으로 한 새로운 방색의 four-port BPSK 직접 변환 수신기를 제안하고 검증한다. 제안한 직접 변환 수신기는 두 개의 능동 결합기, 집중 소자 LC 발룬, 두 개의 전력 검출기, 그리고 아날로그 디코더로 구성되어 있다. 설계된 직접 변환 수신기는 K-bnad 반송파 주파수의 데이터율 40 Mbps까지의 BPSK 변조 신호를 성공적으로 복조하였다. In this paper, we propose and demonstrate a new four-port BPSK direct conversion receiver based on 0.18 ㎛ CMOS technology for K-band applications. The proposed direct conversion receiver is composed of two active combiners, an lumped LC balun, two power detectors and an analog decode. The designed direct conversion receiver is successfully demodulated BPSK signal with 40 Mbps in the K-band.

      • KCI등재

        저항 부하된 소형 다이폴을 이용한 3축 등방성 전기장 프로브 설계

        성원(Sung-Won Moon),장병준(Byung-Jun Jang) 한국전자파학회 2017 한국전자파학회논문지 Vol.28 No.3

        본 논문에서는 저항 부하를 갖는 소형 다이폴을 이용하여 3축 등방성 전기장 측정 프로브를 설계하였다. 특히, 상용저항소자와 PCB를 이용함으로써 상용화에 장점이 있다. 설계된 전기장 측정 프로브는 저항 부하로 인한 광대역 특성으로 100 kHz에서 3 GHz까지의 광대역 특성을 갖는다. 제작 결과 광대역에 걸쳐 ±0.39 dB 이내의 등방성 특성, 0.1 V/m의 수신감도 특성, 3 dB 이내의 주파수 응답 특성을 얻었다. 특히 250 kHz에서 3 GHz까지의 주파수 응답 특성은 ±1.4 dB의 우수한 특성을 보여 기존 전기장 프로브에 비해 우수한 특성 개선을 보였다. In this paper, we designed the 3-axis isotropic electric-field measurement probe using resistor-loaded short dipole with lumped chip resistors. The designed probe shows good isotropic characteristics as well as wideband and low sensitivity. The isotropic characteristics of ±0.39 dB from 100 kHz to the 3 GHz band were derived and the reception sensitivity was 0.1 V/m. The frequency response is within 3 dB of the whole section, especially ±1.3 dB from 150 kHz to 3 GHz, which is superior to the conventional electric field probe with short dipoles.

      • KCI등재

        제주도의 효율적인 외자유치 전략

        문원석(Moon Won-Suk) 한국문화산업학회 2006 문화산업연구 Vol.6 No.1

        Jeju Provincial Government has recently implemented various legal and economic revisions to provide for Jeju Island's development into a free international island. But the main goal of these revisions, namely, to induce private investment, has not been achieved. The key reason for this failure to induce private investment is that policy markers have not cultivated the reliability necessary to develop confidence among international investors. Without this confidence it is not possible to create income through business activities in Jeju Island. To induce International investment, Jeju Island must promote a special emphasis on the specific advantage of local investment in order to attract firms based outside of Korea. To this effect, the purpose of this paper is to explore the existing weaknesses in policy regarding the inducement process for foreign investment in Jeju Island. In addition, this paper offers strategies for a more efficient inducement of international investment in Jeju Free International Island. Jeju Provincial Government has recently implemented various legal and economic revisions to provide for Jeju Island's development into a free international island. But the main goal of these revisions, namely, to induce private investment, has not been achieved. The key reason for this failure to induce private investment is that policy markers have not cultivated the reliability necessary to develop confidence among international investors. Without this confidence it is not possible to create income through business activities in Jeju Island. To induce International investment, Jeju Island must promote a special emphasis on the specific advantage of local investment in order to attract firms based outside of Korea. To this effect, the purpose of this paper is to explore the existing weaknesses in policy regarding the inducement process for foreign investment in Jeju Island. In addition, this paper offers strategies for a more efficient inducement of international investment in Jeju Free International Island.

      • KCI등재

        논문 : 로컬리티와 타자

        성원 ( Sung Won Moon ) 한국철학사상연구회 2010 시대와 철학 Vol.21 No.2

        이른바 세계화의 시대에 지역성과 국지성(局地性)을 특징으로 하는 로컬리티의 문제는 반(反)보편주의의 비판적 함의를 지닌다. 이 논문은, 로컬리티를 주체상관적인 현상학적 장소의 문제로 다루는 데서 출발하여, 단순한 반보편주의를 넘어서는 로컬리티의 변화 지향적인 의미를 타자의 수용문제와 관련하여 궁구하고자 한다. 여기서 주요한 이론적 전거가 되는 철학자는 에마뉘엘 레비나스이다. 레비나스에게서 로컬리티를 본격적으로 논할 수 있는 것은 거주(居住)의 계기에서다. 거주란 분리된 존재인 유한자가 향유의 불안정성을 극복하기 위해 취하는 자리 잡음(localization)이라고 할 수 있다. 레비나스에 따르면, 거주지로서의 집은 세계의 한 지점에 불과한 것이 아니라 객관적인 세계의 출발점이자 기반이다. 더욱이 거주에는 레비나스 철학의 주요 개념인 타자(他者)와 환대(歡待)의 계기가 이미 들어와 있다. 이미 내가 내 거처에 받아들여졌듯이, 타자 또한 나에 의해 내 거주지에 받아들여질 수 있다. 이렇게 타자를 환대할 여지를 지닌 로컬리티는 기존의 동일자적 질서를 넘어서는 변화의 지점으로서 부각된다. The problematics of locality implies a critique of the universalization in the epoch of globalization. Over such a critique, this paper will investigate the radical meanings of locality, starting from the phenomenological view in which it is treated not as a part of the abstract space but as a place relative to a subject. Especially, the receptibility of the other in locality would be discussed with reference to the philosophy of Emmanuel Levinas. It is in the moment of dwelling that the locality could be an important issue in Levinas` thoughts. The dwelling is a localization of the existent, the separated being, to overcome the instability of enjoyment. Hence, the habitation or the home as a dwelling place is not just a point of the world but a base of the world. Besides, the dwelling involves the moment of hospitality, for I have been accepted in my habitation already. It can be a ground for the hospitality of the other. The locality where such a hospitality is permitted, might be open to the changes beyond the established order of the same.

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