http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Easy Diagnosis of Asthma: Computer-Assisted, Symptom-Based Diagnosis
Choi, Byoung Whui,Yoo, Kwang-Ha,Jeong, Jae-Won,Yoon, Ho Joo,Kim, Sang-Heon,Park, Yong-Mean,Kim, Wo-Kyung,Oh, Jae-Won,Rha, Yeong-Ho,Pyun, Bok-Yang,Chang, Suk-Il,Moon, Hee-Bom,Kim, You-Young,Cho, Sang-H KOREAN ACADEMY OF MEDICAL SCIENCE 2007 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.22 No.5
<P>Diagnosis of asthma is often challenging in primary-care physicians due to lack of tools measuring airway obstruction and variability. Symptom-based diagnosis of asthma utilizing objective diagnostic parameters and appropriate software would be useful in clinical practice. A total of 302 adult patients with respiratory symptoms responded to a questionnaire regarding asthma symptoms and provoking factors. Questions were asked and recorded by physicians into a computer program. A definite diagnosis of asthma was made based on a positive response to methacholine bronchial provocation or bronchodilator response (BDR) testing. Multivariate logistic regression analysis was used to evaluate the significance of questionnaire responses in terms of discriminating asthmatics. Asthmatic patients showed higher total symptom scores than non-asthmatics (mean 5.93 vs. 4.93; <I>p</I><0.01). Multivariate logistic regression analysis identified that response to questions concerning the following significantly discriminated asthmatics; wheezing with dyspnea, which is aggravated at night, and by exercise, cold air, and upper respiratory infection. Moreover, the presence of these symptoms was found to agree significantly with definite diagnosis of asthma (by kappa statistics). Receiver-operating characteristic curve analysis revealed that the diagnostic accuracy of symptom-based diagnosis was high with an area under the curve of 0.647±0.033. Using a computer-assisted symptom-based diagnosis program, it is possible to increase the accuracy of diagnosing asthma in general practice, when the facilities required to evaluate airway hyperresponsiveness or BDR are unavailable.</P>
S-280 : A case of paragonimiasis presented with pseudochylothorax
( Young Hwan Choi ),( Cheol Won Hyeon ),( Jae Woo Jung ),( Jae Chol Choi ),( Jong Wook Shin ),( Jae Yeol Kim ),( In Won Park ),( Byoung Whui Choi ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1
A pseudochylothorax, also known as cholesterol pleurisy or chyliform effusion that contains cholesterol crystals or high lipid content, is a rare lung disease. Although there have been several reported cases of pseudochylothorax associated with paragonimiasis, paragonimiasis is still a rare cause of pseudochylothorax. Moreover, no case of pleural paragonimiasis presented with pseudochylothroax has been reported in Korea. We report a case of Paragonimus westermani with unilateral pseudochylothorax A 93-year-old man was admitted to our hospital for progressive dyspnea with one week history of cough and sputum. He had a history of paragonimiasis 30years previously which had been successfully treated with mebendazol. He denied a recent history of ingestion of raw freshwater crab. Laboratory tests revealed a white blood cell count (WBC) was 8390 cells/mm3 (67% neutrophils, 16% lymphocytes, 1% eosinophils), hemoglobin 14.9 g/dL, platelet count 148,000/mm3 and the C-reactive protein was 10.97 mg/L. His chest radiographs showed right pleural effusion, thickening and calcification and chest CT scan detected no apparent abnormal pulmonary infiltrations or mediastinal lymph node swelling. Ultra-sound-guided percutaneous catheter drainage (PCD) was performed for diagnostic and therapeutic reasons. Pleural effusions from both pleural cavities were turbid and milky yellow. On biochemical examination this fluid was found to have a specific gravity of 1.035, pH 7.16, triglyceride 14 mg/dL, cholesterol 178 mg/dL, glucose 8 mg/dL, LDH 3195 IU/L, protein 7.0 g/dL and adenosine deaminase 43.4 IU/L. The cell cont was 50 cells/mm3 (neutrophils 71%, lymphocytes 28% and eosinophils 1%). Characteristic operculated eggs consistent with P. westermani and typical rhomboidal cholesterol crystals were noted on microscopic examination. The patient was treated with praziquantel (1,500 mg t.i.d. for 2 days). This case suggests that paragonimiasis should be included in the differential diagnosis of pseudochylothorax even if blood and pleural fluid eosinophilia are not detected.
연구보고 : 기관지천식환자에 있어서 고해상도 전산화단층촬영술을 이용한 기관지유발에 대한 기도의 반응
최병휘 ( Byoung Whui Choi ),강윤정 ( Yoon Jeong Kang ),고형기 ( Hyung Ki Ko ),박인원 ( In Won Park ),허성호 ( Sung Ho Hue ),김양수 ( Yang Soo Kim ),김영구 ( Young Goo Kim ),김건상 ( Kun Sang Kim ),김종효 ( Jong Hyo Kim ) 대한결핵 및 호흡기학회 1995 Tuberculosis and Respiratory Diseases Vol.42 No.6
기관지 천식 환자에서 혈청 IL - 6 , ICAM - 1 , RANTES 농도 측정의 임상적 의의
최재선(Jae Sun Choi),이병훈(Byung Hoon Lee),안창혁(Chang Hyuk Ahn),유지훈(Ji Hoon Yoo),나문준(Moon Jun Na),김재열(Jae Yeol Kim),박인원(In Won Park),최병휘(Byung Whui Choi),허성호(Sung Ho Hue) 대한내과학회 1998 대한내과학회지 Vol.55 No.5
N/A Bronchial asthma is a chronic airway inflammation disorder involving lymphocyte activation and various cytokines secretion by lymphocyte. The inflammatory response results from a complex network of interactions between inflammatory cells (mast cells, eosinophils, macrophages) and resident cells belonging to the lung structure itself like EC, fibroblasts, or bronchial epithelial cells. IL-6 which is known to up-regulate the endothelial cell expression of adhesion molecules participating in the development of the inflammatory reaction in bronchial asthma is produced by alveolar macrophage. ICAM-1 is produced by bronchial epithelial cell and expression by endothelial cell, which is known to enhance of the influx of various cells, RANTES which is known to a potent chemoattractant for eosinophils, lymphocytes, and monocytes, a member of the CC chemokine family, is expressed by bronchial epithelial cell. To evaluate whether markers of lymphocyte activation are useful markers of disease activity in bronchial asthma, we measured slL-6, sICAM- 1, sRANTES in 42 patients with mild to moderate bronchial asthma and in 26 normal controls and con the result with other disease activity markers in asthma(pulmonary function, blood eosinophil counts). The mean level of sIL-6 was higher than that of normal control and correlated significantly with sICAM-1, FEV1% to predicted value. The mean level of sICAM-1 was higher than that of normal control and correlated significantly with FEV1%, FEV1% to predicted value. The mean level of sRANTES showed the tendency to be higher than that of normal control, but not significant statistically, and did not correlated with sIL-6, sICAM-1, FEV1%, FEV1% to predicted value, blood eosinophil counts. It appeared that sIL-6 and sICAM-1 could be a disease marker in bronchial asthma. But, clinical application of the measurement of these markers needs to be studied further.