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- 저자 : Wenjie Tian (검색결과 6 건)
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Wenjie Tian,Guang Yang,Lina Wang,Fuwen Yin,Weiguo Gao 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.10
Geometric accuracy is crucially important for machine tools. Identification of geometric errors, especially position-dependent geometric errors, is still a challenging issue. This paper presents a systematic and fast approach to identify the geometric error components of a precision machine tool using double ball bar (DBB). The approach can be implemented in three steps: (1) polynomial based error modeling that relates the DBB radius error directly to the geometric error parameters of machine tool; (2) spatial measurement trajectory planning with a single installation of DBB in order to avoid producing extra setup errors; (3) error identification with regularization method that can solve the ill-posed identification problem effectively. Simulations and experiments show the accuracy and effectiveness of the proposed identification approach. The results of the DBB test show that, utilizing the proposed identification method, the roundness errors of the three circular paths in xy-, yz- and xz-plane are reduced from 27.3 μm, 20.7 μm and 24.1 μm to 9.2 μm, 12.3 μm and 7.8 μm, respectively, with error compensation.
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Design and Implementation of a High Power Three-Level T-Type Inverter for a Photovoltaic System
Yang Xuan,Mofan Tian,Xiaomei Song,Wenjie Chen,Xu Yang 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
Nowadays, the grid-connected photovoltaic systems are an important part of the renewable energy sources, and their performance is getting more and more important. Many reported researches focused on the traditional NPC topology. However, few researches were about the T-type NPC inverter. In this paper, a high power three-phase T-type neutral point clamped grid connected photovoltaic inverter prototype is designed and implemented. The design and implementation procedure of the inverter is discussed in detail. Experimental results showed that the output power of the proposed inverter could reach up to 100kW with unit power factor, while the total harmonic distortion of the grid current was less than 3%. And the total efficiency of the system is measured as 95.6%. The experimental results demonstrated the T-type NPC inverter can operate with a good performance.
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Antimicrobial and Cytotoxic Activity of Endophytic Fungi from Lagopsis supina
Zhang Dekui,Sun Weijian,Xu Wenjie,Ji Changbo,Zhou Yang,Sun Jingyi,Tian Yutong,Li Yanling,Zhao Fengchun,Tian Yuan 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.4
In this study, five endophytic fungi belonging to the Aspergillus and Alternaria genera were isolated from Lagopsis supina. The antimicrobial activity of all fungal fermented extracts against Staphylococcus and Fusarium graminearum was tested using the cup-plate method. Among them, Aspergillus ochraceus XZC-1 showed the best activity and was subsequently selected for large-scale fermentation and bioactivity-directed separation of the secondary metabolites. Four compounds, including 2- methoxy-6-methyl-1,4-benzoquinone (1), 3,5-dihydroxytoluene (2), oleic acid (3), and penicillic acid (4) were discovered. Here, compounds 1 and 4 displayed anti-fungal activity against F. graminearum, F. oxysporum, F. moniliforme, F. stratum, Botrytis cinerea, Magnaporthe oryzae, and Verticillium dahliae with diverse MIC values (128–512 μg/ml), which were close to that of the positive control antifungal, actidione (64–128 μg/ml). Additionally, compounds 1 and 4 also exhibited moderate antibacterial activity against S. aureus, Listeria monocytogenes, Escherichia coli, and Salmonella enterica, with low MIC values (8–64 μg/ml). Moreover, compounds 1 and 4 displayed selective cytotoxicity against cancer cell lines as compared with the normal fibroblast cells. Therefore, this study proposes that the endophytic fungi from L. supina can potentially produce bioactive molecules to be used as lead compounds in drugs or agricultural antibiotics.
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Low-Intensity Shock Wave Therapy and Its Application to Erectile Dysfunction
Hongen Lei,Jing Liu,Huixi Li,Lin Wang,Yongde Xu,Wenjie Tian,Guiting Lin,Zhongcheng Xin 대한남성과학회 2013 The World Journal of Men's Health Vol.31 No.3
Although phosphodiesterase type 5 inhibitors (PDE5Is) are a revolution in the treatment of erectile dysfunction (ED) and have been marketed since 1998, they cannot restore pathological changes in the penis. Low-energy shock wave therapy (LESWT) has been developed for treating ED, and clinical studies have shown that LESWT has the potential to affect PDE5I non-responders with ED with few adverse effects. Animal studies have shown that LESWT significantly improves penile hemodynamics and restores pathological changes in the penis of diabetic ED animal models. Although the mechanisms remain to be investigated, recent studies have reported that LESWT could partially restore corpus cavernosum fibromuscular pathological changes, endothelial dysfunction, and peripheral neuropathy. LESWT could be a novel modality for treating ED, and particularly PDE5I non-responders with organic ED, in the near future. However, further extensive evidence-based basic and clinical studies are needed. This review intends to summarize the scientific background underlying the effect of LESWT on ED.
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RPTOR methylation in the peripheral blood and breast cancer in the Chinese population
Yin Yifei,Lei Shuifang,Li Lixi,Yang Xiaoqin,Yin Qiming,Xu Tian,Zhou Wenjie,Li Hong,Gu Wanjian,Ma Fei,Yang Rongxi,Zhang Zhengdong 한국유전학회 2022 Genes & Genomics Vol.44 No.4
Background: Altered regulatory-associated protein of mTOR, complex 1 (RPTOR) methylation levels in peripheral blood was originally discovered as breast cancer (BC)-associated risk factor in Caucasians. Objective: To explore the relationship between RPTOR methylation and BC in the Chinese population, we conducted two independent case-control studies. Methods: Peripheral blood samples were collected from a total of 333 sporadic BC cases and 378 healthy female controls for the DNA extraction and bisulfite-specific PCR amplification. Mass spectrometry was applied to quantitatively measure the levels of methylation. The logistic regression, Spearman's rank correlation, and Non-parametric tests were used for the statistical analyses. Results: In our study, we found an association between BC and RPTOR_CpG_4 hypomethylation in the general population (per-10% of methylation, OR 1.29, P = 0.012), and a weak association between BC and RPTOR_CpG_8 hypomethylation in the women with older age (per-10% of methylation, OR 2.34, P = 0.006). We also identified age as a confounder for the change of RPTOR methylation patterns, especially at RPTOR_CpG_4, which represented differential methylation comparing age groups especially in the BC cases (age < 50 years vs age ≥ 50 years by Mann-Whitney U test, P < 0.0001 for BC cases and P = 0.079 for controls). Conclusion: Our study validated the association between hypomethylation of RPTOR and BC risk in the Chinese population also with weak effect and mostly for postmenopausal women. In addition, our findings provided novel insight for the regulation of DNA methylation upon aging or the change of hormone levels.
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