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Wei‑dong Zhang,Junye Ren,Bin Liu,Yong Liu,Zhenggang Wu,Jingwen Qiu 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.7
Ti–36Nb–2Ta–3Zr–0.35O (TNTZO) alloy is an excellent candidate for biomedical applications. In this study, a new methodcombining cold-swaging and cold-drawing was used to fabricate the TNTZO alloy wires with 0.3 mm diameter for orthodonticapplications. The microstructure and mechanical properties of cold-drawn and annealed TNTZO wires (referred toas TNTZO0.3and TNTZO0.3(HT), respectively) were investigated. The results show that the microstructure of cold drawnTNTZO0.3consists of main-sized elongated grains with 70 nm width. After annealing at 700 °C for 5 min, the microstructureof TNTZO0.3(HT) wires becomes equiaxial with a grain size of ~ 5 μm. The cold drawn TNTZO0.3wires exhibit improvedmechanical properties, higher tensile strength (about 1000 MPa) and similar elastic modulus (69 GPa), compared to annealedTNTZO0.3(HT) wires. Besides, TNTZO0.3has higher creep resistance and lower stress exponent (around 2), compared to Tiwires and TC4 wires with the same diameter. These results prove that TNTZO0.3wires have most of the ideal characteristicsof orthodontic wires.
Wei, Wei-Hong,Cai, Xiu-Yu,Xu, Tao,Zhang, Guo-Yi,Wu, Yong-Feng,Feng, Wei-Neng,Lin, Li,Deng, Yan-Ming,Lu, Qiu-Xia,Huang, Zhe-Li Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3
Background and Purpose: Cisplatin is the most common chemotherapeutic agent for loco-regionally advanced nasopharyngeal carcinoma (NPC); however, toxicity is a limiting factor for some patients. We retrospectively compared the efficacy and toxicity of weekly docetaxel-based and cisplatin-based concurrent chemoradiotherapy in loco-regionally advanced NPC. Methods and Materials: Eighty-four patients with Stage III and IVA-B NPCs, treated between 2007 and 2008, were retrospectively analyzed. Thirty received weekly docetaxel-based concurrent chemotherapy, and 43 were given weekly cisplatin-based concurrent chemotherapy. Radiotherapy was administered using a conventional technique (seven weeks, 2.0 Gy per fraction, total dose 70-74 Gy) with 6-8 Gy boosts for some patients with locally advanced disease. Results: Median follow-up time was 42.3 months (range, 8.6-50.8 months). There were no significant differences in the 3-year loco-regional failure-free survival (85.6% vs. 92.3%; p=0.264), distant failure-free survival (87.0% vs. 92.5%; p=0.171), progression-free survival (85.7% vs. 88.4%; p=0.411) or overall survival (86.5% vs. 92.5%, p=0.298) of patients treated concurrently with docetaxel or cisplatin. Severe toxicity was not common in either group. Conclusions: Weekly docetaxel-based concurrent chemoradiotherapy is potentially effective and has a tolerable toxicity; however, further investigations are required to determine if docetaxel is superior to cisplatin for advanced stage NPC.
Wei Peng,Teng-wei Qiu,Chun-yan Yao,Chen Tang,Wei Zhang 한국정밀공학회 2015 International Journal of Precision Engineering and Vol. No.
This paper proposes a method of free-abrasive wire sawing in the magnetic field. Magnetic abrasive grains are absorbed on surface of the wire by magnetic force, and therefore more magnetic abrasive grains are carried into cutting area. This mechanism is helpful to improve the cutting performance of wire saws. Theoretical modeling of the movement trajectory of magnetic abrasive grains is done in the magnetic field, and it is also verified by observation experiments of movement trajectory of magnetic abrasive grains. Absorption angle, which is used as the indicator of adsorption capacity about magnetic abrasive grain on surface of the wire, is proposed in this paper. The effect of magnetic field intensity on absorption angle is analyzed through computer simulations and observation experiments. Practical experiments and cutting results show that the change of magnetic field intensity has a significant impact on cutting efficiency, surface roughness, and kerf width.
Wei Qiu,Guo-Yue Lv,Chao Jiang,Ping Zhang,Xiao-Dong Sun,Xiao-Ju Shi,Xue-Yan Liu,Guang-Yi Wang 한국간담췌외과학회 2016 Annals of hepato-biliary-pancreatic surgery Vol.20 No.1
Acute graft-versus-host disease (GVHD) following liver transplantation is a rare but fatal complication. The correct diagnosis and management of GVHD after liver transplantation are still major challenges. Herein, we reported successful salvage treatment of acute GVHD by withdrawal of immunosuppression in a patient who presented with fever, skin rashes, and decreased blood cell counts after liver transplantation. This case highlights the need for awareness of drug-induced liver injury if liver function tests are elevated during treatment, especially in patients taking multiple potentially hepatotoxic drugs, such as broad-spectrum antibiotics. When occurs, an artificial liver support system is a useful tool to provide temporary support of liver function for the patient in the event of drug-induced liver injury.
Influence of Frequency on Electromagnetic Field of Super High-Speed Permanent Magnet Generator
Qiu, Hongbo,Wei, Yanqi,Wang, Wei,Tang, Bingxia,Zhao, Xifang,Yang, Cunxiang The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.4
When compared with traditional power frequency generators, the frequency of a super high-speed permanent magnet generator (SHSPMG) is a lot higher. In order to study the influence of frequency on the electromagnetic field of SHSPMGs, a 60000rpm, 117kW SHSPMG was taken as a research object. The two-dimensional finite element model of the generator was established, and the two-dimensional transient field of the generator was simulated. In addition, a test platform of the generator was set up and tested. The reliability of the simulation was verified by comparing the experiment data with that of the simulation. Then the generator electromagnetic field under different frequencies was studied, and the influence mechanism of frequency on the generator electromagnetic field was revealed. The generator loss, voltage regulation rate, torque and torque ripple were analyzed under the rated active power load and different frequencies. The influences of frequency on the eddy current density, loss, voltage regulation rate and torque ripple of the generator were obtained. These conclusions can provide some reference for the design and optimization of SHSPMGs.
Qiu, Hao,Duan, Wei-Ming,Shu, Jie,Cheng, Hong-Xia,Wang, Wei-Ping,Huang, Xin-En,Chen, Hui-Li Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24
The epidermal growth factor receptor (EGFR) is an important surface receptor with N-glycans in its extracellular domain, whose glycosylation is essential for its function, especially in tumor cells. Here, we demonstrated that polylactosamine is markedly increased in H7721 hepatocellular carcinoma cells after treatment with EGF, while it apparently declined after exposure to all-trans retinoic acid (ATRA). In the study of the enzymatic mechanism of this phenomenon, we explored changes in the expression of poly-N-acetyllactosamine (PLN) branching glycosyltransferases using RT-PCR. Among the four glycosyltransferases with altered expression, GnT-V was most elevated by EGF, while GnT-V and B3GNT2 were most declined by ATRA. Next, we conducted co-immunoprecipitation experiments to test whether B3GNT2 and EGFR associate with each other. We observed that EGFR is a B3GNT2-targeting protein in H7721 cells. Taken together, these findings indicated that the altered expression of B3GNT2 will remodel the PLN stucture of EGFR in H7721 cells, which may modify downstream signal transduction.
Wei Qiu,Guo-Yue Lv,Chao Jiang,Ping Zhang,Xiao-Dong Sun,Xiao-Ju Shi,Xue-Yan Liu,Guang-Yi Wang 한국간담췌외과학회 2016 한국간담췌외과학회지 Vol.20 No.1
Acute graft-versus-host disease (GVHD) following liver transplantation is a rare but fatal complication. The correct diagnosis and management of GVHD after liver transplantation are still major challenges. Herein, we reported successful salvage treatment of acute GVHD by withdrawal of immunosuppression in a patient who presented with fever, skin rashes, and decreased blood cell counts after liver transplantation. This case highlights the need for awareness of drug-induced liver injury if liver function tests are elevated during treatment, especially in patients taking multiple potentially hepatotoxic drugs, such as broad-spectrum antibiotics. When occurs, an artificial liver support system is a useful tool to provide temporary support of liver function for the patient in the event of drug-induced liver injury.
Onset of adrenal ganglioneuroblastoma in an adult after delivery
Wei Qiu,Ting Li,Xiao Dong Sun,Guo Yue Lv 대한외과학회 2015 Annals of Surgical Treatment and Research(ASRT) Vol.89 No.4
A case of adrenal ganglioneuroblastoma is presented here. This adrenal ganglioneuroblastoma was found in a 27-yearold female 7 months after delivery. CT clarified that the tumor originated retroperitoneally and was large in size (11.4 cm × 9.4 cm). The tumor was surgically removed together with pancreatic body and tail, left kidney and spleen, and pathological diagnosis was adrenal ganglioneuroblastoma-intermixed. Adrenal ganglioneuroblastoma is extremely rare in adults, with only about 9 cases documented including this case.
Influence of Frequency on Electromagnetic Field of Super High-Speed Permanent Magnet Generator
Hongbo Qiu,Yanqi Wei,Wei Wang,Bingxia Tang,Xifang Zhao,Cunxiang Yang 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.4
When compared with traditional power frequency generators, the frequency of a super high-speed permanent magnet generator(SHSPMG) is a lot higher. In order to study the influence of frequency on the electromagnetic field of SHSPMGs, a 60000rpm,117kW SHSPMG was taken as a research object. The two-dimensional finite element model of the generator was established,and the two-dimensional transient field of the generator was simulated. In addition, a test platform of the generator was set upand tested. The reliability of the simulation was verified by comparing the experiment data with that of the simulation. Then thegenerator electromagnetic field under different frequencies was studied, and the influence mechanism of frequency on thegenerator electromagnetic field was revealed. The generator loss, voltage regulation rate, torque and torque ripple were analyzedunder the rated active power load and different frequencies. The influences of frequency on the eddy current density, loss, voltageregulation rate and torque ripple of the generator were obtained. These conclusions can provide some reference for the designand optimization of SHSPMGs.
Changjian Qiu,Yuan Feng,Yajing Meng,Wei Liao,Xiaoqi Huang,Su Lui,Chunyan Zhu,Huafu Chen,Qiyong Gong,Wei Zhang 대한신경정신의학회 2015 PSYCHIATRY INVESTIGATION Vol.12 No.3
ObjectiveaaWe hypothesize that the amplitude of low-frequency fluctuations (ALFF) is involved in the altered regional baseline brain function in social anxiety disorder (SAD). The aim of the study was to analyze the altered baseline brain activity in drug-naive adult patients with SAD. MethodsaaWe investigated spontaneous and baseline brain activities by obtaining the resting-state functional magnetic resonance imaging data of 20 drug-naïve adult SAD patients and 19 healthy controls. Voxels were used to analyze the ALFF values using one- and two-sample t-tests. A post-hoc correlation of clinical symptoms was also performed. ResultsaaOur findings show decreased ALFF in the bilateral insula, left medial superior frontal gyrus, left precuneus, left middle temporal gyrus, right middle temporal pole, and left fusiform gyrus of the SAD group. The SAD patients exhibited significantly increased ALFF in the right inferior temporal gyrus, right middle temporal gyrus, bilateral middle occipital gyrus, orbital superior frontal gyrus, right fusiform gyrus, right medial superior frontal gyrus, and left parahippocampal gyrus. Moreover, the Liebowitz Social Anxiety Scale results for the SAD patients were positively correlated with the mean Z values of the right middle occipital and right inferior occipital but showed a negative correlation with the mean Z values of the right superior temporal gyrus and right medial superior frontal gyrus. ConclusionaaThese results of the altered regional baseline brain function in SAD suggest that the regions with abnormal spontaneous activities are involved in the underlying pathophysiology of SAD patients.