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Lin Meng-Ying,Wu Cheng-Lin,Su Yung-Yeh,Huang Chien-Jui,Chang Wei-Lun,Sheu Bor-Shyang 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.2
Background/Aims: A high-quality sample allows for next-generation sequencing and the administration of more tailored precision medicine treatments. We aimed to evaluate whether heparinized wet suction can obtain higher quality samples than the standard dry-suction method during endoscopic ultrasound (EUS)-guided biopsy of pancreatic masses. Methods: A prospective randomized crossover study was conducted. Patients with a solid pancreatic mass were randomly allocated to receive either heparinized wet suction first or dry suction first. For each method, two needle passes were made, followed by a switch to the other method for a total of four needle punctures. The primary outcome was the aggregated white tissue length. Histological blood contamination, diagnostic performance and adverse events were analyzed as secondary outcomes. In addition, the correlation between white tissue length and the extracted DNA amount was analyzed. Results: A total of 50 patients were enrolled, and 200 specimens were acquired (100 with heparinized wet suction and 100 with dry suction), with one minor bleeding event. The heparinized wet suction approach yielded specimens with longer aggregated white tissue length (11.07 mm vs 7.96 mm, p=0.001) and less blood contamination (p=0.008). A trend towards decreasing tissue quality was observed for the 2nd pass of the dry-suction method, leading to decreased diagnostic sensitivity and accuracy, although the accumulated diagnostic performance was comparable between the two suction methods. The amount of extracted DNA correlated positively to the white tissue length (p=0.001, Spearman̕s ρ=0.568). Conclusions: Heparinized wet suction for EUS tissue acquisition of solid pancreatic masses can yield longer, bloodless, DNA-rich tissue without increasing the incidence of adverse events (ClinicalTrials.gov. identifier NCT04707560).
Yeh, Wei-Ching,Lin, Hsi-Yen,Jhaot, Jhen-Bo Techno-Press 2007 Structural Engineering and Mechanics, An Int'l Jou Vol.25 No.4
By using the incremental form of the endochronic theory of plasticity, a model of material function is proposed in this paper to investigate plastic behavior. By comparing the stress-strain hysteresis loop, the theory is shown to agree well with the experimental results, especially in the evolution of peak stress values of SAE 4340 steel loaded by cyclic loading with various amplitudes. Depending on the choice of material parameters, the present model can substantially result in six categories of material function, each of which can behave differently with respect to an identical deformation history. In addition, the present model of material function is shown to be capable of describing the behavior of erasure of memory of materials, as experimentally observed by Lamba and Sidebottom (1978).
Ultrasound imaging for inguinal hernia: a pictorial review
Wei-Ting Wu,Ke-Vin Chang,Chih-Peng Lin,Chi-Chuan Yeh,Özçakar Levent 대한초음파의학회 2022 ULTRASONOGRAPHY Vol.41 No.3
Inguinal hernia is the most prevalent type of abdominal wall hernia. Indirect inguinal hernia is twice as common as direct inguinal hernia. Computed tomography and magnetic resonance imaging can be used to evaluate inguinal hernia, but these modalities are greatly limited by their cost and availability. Ultrasonography has emerged as the most convenient imaging tool for diagnosing inguinal hernia due to its advantages, such as portability and absence of radiation. The present pictorial review presents an overview on the use of ultrasonography in the evaluation of inguinal hernia with a particular emphasis on the regional anatomy, relevant scanning tips, identification of subtypes, postoperative follow-up, and diagnosis of pathologies mimicking inguinal hernia.
Wei-Ching Yeh,Hsi-Yen Lin,Jhen-Bo Jhao 국제구조공학회 2007 Structural Engineering and Mechanics, An Int'l Jou Vol.25 No.4
By using the incremental form of the endochronic theory of plasticity, a model of material function is proposed in this paper to investigate plastic behavior. By comparing the stress-strain hysteresis loop, the theory is shown to agree well with the experimental results, especially in the evolution of peak stress values of SAE 4340 steel loaded by cyclic loading with various amplitudes. Depending on the choice of material parameters, the present model can substantially result in six categories of material function, each of which can behave differently with respect to an identical deformation history. In addition, the present model of material function is shown to be capable of describing the behavior of erasure of memory of materials, as experimentally observed by Lamba and Sidebottom (1978).
FingerTalk: Real-time Fingertip Trajectories Tracking Service based on IoTtalk
Yun-Wei Lim,Lin-Hang Kao,Chun-Ting Yeh 한국통신학회 2020 한국통신학회 APNOMS Vol.2020 No.09
Internet of Things (IoT) integrates with finger tracking and 3D signature verification can provide the user authentication service for these IoT applications which require user identification and authorization, such as the home automation and security system. This work develops two modules. The FingerTalk module provides the fingertip trajectories tracking service based on a Leap Motion camera and IoTtalk. The AirSig module provides 3D signature verification service to recognize whether a signature is signed form the authenticated user. The AirSig module requires only two user signature samples to train the neural network model which significantly reduces the process time for signature collection. The validation results from 10 people show the average accuracy is up to 93.6% on 3D signature verification.
I-Mei Lin,Sheng-Yu Fan,Cheng-Fang Yen,Yi-Chun Yeh,Tze‐Chun Tang,Mei-Feng Huang,Tai-Ling Liu,Peng-Wei Wang,Huang-Chi Lin,Hsin-Yi Tsai,Yu-Che Tsai 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.2
Objective: Autonomic imbalance is considered a psychopathological mechanism underlying major depressive disorder (MDD). Heart rate variability (HRV) is an index for autonomic activation. Poor sleep quality is common among patients with MDD. HRV biofeedback (BF) has been used for regulating autonomic balance among patients with physical illness and mental disorders. The purpose of present study was to examine the effects of HRV-BF on depressive symptoms, sleep quality, pre-sleep arousal, and HRV indices, in patients with MDD and insomnia. Methods: In this case-controlled study, patients with MDD and Pittsburgh Sleep Quality Index (PSQI) score higher than 6 were recruited. The HRV-BF group received weekly 60-minute protocol for 6 weeks, and the control group who have matched the age and sex received medical care only. All participants were assessed on Beck Depression Inventory-II, Back Anxiety Inventory, PSQI, and Pre-Sleep Arousal Scale. Breathing rates and electrocardiography were also performed under resting state at pre-testing, and post-testing conditions and for the HRV-BF group, also at 1-month follow-up. Results: In the HRV-BF group, symptoms of depression and anxiety, sleep quality, and pre-sleep arousal were significantly improved, and increased HRV indices, compared with the control group. Moreover, in the HRV-BF group, significantly improved symptoms of depression and anxiety, decreased breathing rates, and increased HRV indices were detected at post-testing and at 1-month follow-up, compared with pre-testing values. Conclusion: This study confirmed that HRV-BF is a useful psychosocial intervention for improving autonomic balance, baroreflex, and symptoms of depression and insomnia in MDD patients.