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Guanglei Zhao,Zhao Wang,Xiuwei Fu 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.4
This paper investigates the event-triggered consensus problem of multi-agent systems with uncertainties and input saturation. First, a fully distributed robust consensus low-gain feedback control strategy is proposed, in which some global information, such as the communication graph and the scale of network, is not needed. Then, by defining an internal dynamic variable to memory the past state, an adaptive dynamic event-triggering mechanism is proposed, which contributes to reducing the usage of communication resources and also does not rely on any global information. Furthermore, Lyapunov-based consensus analysis results are presented, and it is also formally shown that Zeno behavior can be excluded with the proposed consensus protocols. Finally, a numerical example is provided to illustrate the effectiveness of the proposed results.
H_∞ DOF Control of Stochastic Systems with Time-varying Delay and L_∞ Disturbance
Guanglei Zhao,Jingcheng Wang 제어·로봇·시스템학회 2011 International Journal of Control, Automation, and Vol.9 No.4
This paper considers the problem of H∞ dynamic output feedback (DOF) control for a class of stochastic systems with time-varying delay and L∞ disturbance. A new delay-dependent sufficient condition for the existence of the DOF controller is derived and the controller design method is given in the form of bilinear matrix inequalities (BMIs). Moreover, a variable step size path-following algorithm is proposed to solve the BMI problem. Numerical examples are given to illustrate the effectiveness of the proposed methods.
Stability Analysis of Periodic Triggering Reset Control Systems
Guanglei Zhao,Jingcheng Wang,Bin Zhang 제어·로봇·시스템학회 2015 International Journal of Control, Automation, and Vol.13 No.4
In most literature related to reset control, the reset actions are triggered by continuous monitoring triggering reset conditions, which is not suitable for computer-based implementation. This paper considers periodic triggering reset control, where the reset actions are only triggered at periodically sampling instants. Hybrid system approach is given to analyze the asymptotic stability and L2 gain property, and less conservative switched system approach is presented for asymptotic stability analysis. The comparison of the two approaches is discussed. Moreover, novel reset conditions are given to improve the overshoot performance. Simulations are presented to support our results.
Wang, Zhiqiang,Guillen Quispe, Yanymee N.,Hwang, Seung Hwan,Zuo, Guanglei,Lim, Soon Sung Elsevier 2018 Industrial crops and products Vol.122 No.-
<P><B>Abstract</B></P> <P>Aldose reductase, the pivotal enzyme in the polyol pathway, has been widely investigated as an enzyme critically involved in the onset and progression of various pathologies associated with diabetes mellitus. Investigation of the inhibitory effect of tara [<I>Caesalpinia spinosa</I> (Molina) Kuntze] pods extract on aldose reductase revealed that its <I>n</I>-butanol fraction exhibits excellent aldose reductase inhibitory activity <I>in vitro</I> and <I>ex vivo</I>. Methyl gallate and pistafolin B were isolated from the <I>n</I>-butanol fraction of the tara pod methanolic extract as the main contributors for its aldose reductase inhibition, guided by affinity-based ultrafiltration-high performance liquid chromatography, with pistafolin B being the more potent inhibitor of the two. <I>In vitro</I> and <I>in silico</I> results demonstrated that pistafolin B is a mixed-type inhibitor that can bind to the aldose reductase active site rapidly, preventing substrate access and product formation (IC<SUB>50</SUB>, 0.198 mM; <I>K</I> <SUB>i</SUB>, 0.34 mM). <I>Ex vivo</I> experiments indicated that pistafolin B can penetrate the eye lens and successfully inhibit aldose reductase under hyperglycaemic conditions, thus preventing the accumulation of sorbitol and the subsequent osmotic stress.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The inhibitory effects of tara pods on aldose reductase activity were investigated. </LI> <LI> <I>n</I>-Butanol fraction of tara pods extract showed best aldose reductase inhibition. </LI> <LI> Aldose reductase ultrafiltration-high pressure liquid chromatography was developed. </LI> <LI> Pistafolin B was identified as a novel aldose reductase inhibitor in tara pods. </LI> </UL> </P>
Variations of Immunoglobulins in Colostrum and Immune Milk as Affected by Antigen Releasing Devices
Zhaoa, Shengguo,Zhanga, Chungang,Wang, Jiaqi,Liu, Guanglei,Bu, Dengpan,Cheng, Jinbo,Zhou, Lingyun Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.9
This work was conducted to examine the variation of immunoglobulins (Igs) in serum, immune milk, normal milk and colostrum upon implantation of a new Antigen Releasing Device (ARD). The core of each ARD housed an immunostimulating complex (ISCOM) that was made of adjuvant Quil A and type XIII lipase from a Pseudomonas sp. Each ARD was coated with polylactic acid, known as polylactide, that controls antigen release. Twenty lactating Chinese Holstein cows were divided into 2 groups (n = 10): test group and control group. All cows in the test group were implanted with a single injection in the right iliac lymph node with 3 types of ARDs, which were designed to release the antigens at d 0, 14 and 28 post-implantation. Blood and milk samples were collected from both groups, and colostrum samples were also collected from other post-partum cows in the same farm. Concentrations of $IgG_1$, IgA and IgM in whey and serum were measured by sandwich ELISA. The results showed that the $IgG_1$, IgA and IgM concentrations in serum and whey from the test group were higher than from the control group. Among the three Igs measured, the $IgG_1$ concentration in serum was significantly higher at d 40 after ARD implantation, and the $IgG_1$ concentration in whey peaked at d 9, 17 and 30, which corresponded with release of the antigen. Based on Pearson's correlation between Ig concentration and production parameters, IgA concentration in normal milk was positively correlated with lactation period, which reflected IgA changes during the lactation period in immune milk. In colostrum, $IgG_1$, IgA and IgM decreased abruptly from d 0 to 3, and then decreased slightly. In conclusion, serum $IgG_1$ concentration can be affected by controlled release of the ARD, while whey IgA levels are primarily affected by lactation period. These results may be useful in future studies designed to regulate concentrations of Igs in immune milk.
Hwang, Seung Hwan,Zuo, Guanglei,Wang, Zhiqiang,Lim, Soon Sung Elsevier 2018 Food chemistry Vol.266 No.-
<P><B>Abstract</B></P> <P>A heating model system (HMS) of chlorogenic acid (CGA) and 20 amino acids was produced by heating at 120 °C for 4 h and evaluated for in vitro antioxidant and aldose reductase (AR). The CGA-glutamic acid (GT) HMS showed high in vitro antiradical activity indicated by ABTS<SUP>+</SUP> (82.37%) and DPPH radical scavenging (83.21%) as well as AR (83.21%) inhibition. The structure of the new compound was established by NMR spectroscopy, as methyl-3-(((<I>E</I>)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-4,5-dihydroxycyclohexanecarboxylate (1) and 4-<I>O</I>-caffeoylquinic acid (2) from the CGA-GT HMS. The IC<SUB>50</SUB> values of compound 1 for ABTS<SUP>+</SUP>, DPPH and AR were 8.21, 56.97 and 3.68 μM, respectively. These activities were similar to or higher than those of known positive controls (5.49, 63.58 and 13.60 μM). We suggest that heat treatment generates novel CGA-GT HMS with increased antioxidant and AR inhibitory effects and contributes to the development of novel functional materials from CGA food products.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The newly produced compounds from the CGA-GT heating model system were isolated and characterized. </LI> <LI> The novel CGA derivative showed high in vitro ABTS<SUP>+</SUP> and DPPH radical scavenging activities and aldose reductase inhibitory activity. </LI> <LI> Heating CGA as well as coffee bean with glutamic acid in water may contribute to functional ingredients for treatment of diabetic complications. </LI> </UL> </P>
Yanyan Ren,Hongfeng Li,Guanglei Wu,Le Yang,Chenhui Zheng,LIUDING WANG,Fang Ren,Hui Xing,HONGJING WU 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.2
Al/Fe/Co doped ordered mesoporous carbon (OMC) composites have been synthesized by a facile method, and the influence of dopant on the electromagnetic (EM) and microwave absorption properties was investigated in the frequency range of 2–18 GHz. Compared with Fe/Co– OMC composites, the Al–OMC nanocomposite played a great role in adjusting values and frequency dependence of complex permittivity, which gives rise to significant improved microwave absorption and reduced thickness of the corresponding paraffin wax composites. Reflection loss (RL) values less than -5 dB and -10 dB were obtained in the frequency range of 9.2–18 GHz and 10.7–14.7 GHz with a single thickness of 2.00 mm, respectively. Such enhanced EM wave absorption property of the Al–OMC/paraffin wax composite was ascribed to its superior impedance matching characteristic. Thin thickness, broadband absorption microwave absorbers with Al doped OMC nanocomposites were obtained.
Xingyou Zhang,Bo Chen,Fei Wang,Xin Wang,Yan Cheng,Guanglei Li 대한전기학회 2019 Journal of Electrical Engineering & Technology Vol.14 No.5
Connecting neighbor microgrids into a multi-microgrids system (MMS) is one of research hotspots in the field of microgrids. This paper analyzes difference of distributed generators configuration and load types among each microgrid in a MMS. A method to evaluate the influence of dynamic behaviors and energy exchange behaviors on power supply reliability of microgrids in a MMS is proposed in this paper. A reliability assessment algorithm which takes account of connectivity ability among microgrids and intermittence characteristics of distributed energy, different load type and energy exchange behavior is also proposed in this paper. Since the proposed model can characterize dynamic behavior of microgrids in a MMS, the proposed method is of great significance for design and operation of a MMS.
Guillen Quispe, Yanymee N.,Hwang, Seung Hwan,Wang, Zhiqiang,Zuo, Guanglei,Lim, Soon Sung MDPI 2017 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.18 No.12
<P>This study investigates in vitro targets related to diabetes in 30 herbal extracts from Peru, for the first time, using α-glucosidase, aldose reductase (AR) inhibitory assays and 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) scavenging assays. Among the 30 herbal extracts, <I>Hypericum laricifolium</I> Juss. (HL) was the herb which showed more than 50% inhibition in all assays, presenting 97.2 ± 2.0%, 56.9 ± 5.6%, 81.9 ± 2.5%, and 58.8 ± 4.6% inhibition for the α-glucosidase, AR, DPPH, and ABTS assays, respectively. Finally, six bioactive compounds, namely, protocatechuic acid, chlorogenic acid, caffeic acid, kaempferol 3-<I>O</I>-glucuronide, quercetin, and kaempferol were identified in HL by offline high-performance liquid chromatography (HPLC). Quercetin exhibited the strongest inhibition in all enzyme assays and the strongest antioxidant activity. The results suggest that HL shows great potential for the complementary treatment of diabetes and its complications.</P>