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Long-Term Evolution of the Electrical Stimulation Levels for Cochlear Implant Patients
Jose Luis Vargas,Manuel Sainz,Cristina Roldan,Isaac Alvarez,Angel de la Torre 대한이비인후과학회 2012 Clinical and Experimental Otorhinolaryngology Vol.5 No.4
imObjectives. The stimulation levels programmed in cochlear implant systems are affected by an evolution since the first switch-on of the processor. This study was designed to evaluate the changes in stimulation levels over time and the relationship between post-implantation physiological changes and with the hearing experience provided by the continuous use of the cochlear implant. Methods. Sixty-two patients, ranging in age from 4 to 68 years at the moment of implantation participated in this study. All subjects were implanted with the 12 channels COMBI 40+ cochlear implant at San Cecilio University Hospital, Granada,Spain. Hearing loss etiology and progression characteristics varied across subjects. Results. The analyzed programming maps show that the stimulation levels suffer a fast evolution during the first weeks after the first switch-on of the processor. Then, the evolution becomes slower and the programming parameters tend to be stable at about 6 months after the first switch-on. The evolution of the stimulation levels implies an increment of the electrical dynamic range, which is increased from 15.4 to 20.7 dB and improves the intensity resolution. A significant increment of the sensitivity to acoustic stimuli is also observed. For some patients, we have also observed transitory changes in the electrode impedances associated to secretory otitis media, which cause important changes in the programming maps. Conclusion. We have studied the long-term evolution of the stimulation levels in cochlear implant patients. Our results show the importance of systematic measurements of the electrode impedances before the revision of the programming map. This report also highlights that the evolution of the programming maps is an important factor to be considered in order to determine an adequate calendar fitting of the cochlear implant processor.
Rey David Vargas-Sanchez,Felix Joel Ibarra-Arias,Brisa del Mar Torres-Martinez,Armida Sanchez-Escalante,Gaston Ramon Torrescano-Urrutia 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.11
The present paper reviews the findings of different research studies on the effect of natural ingredients in the Japanese quail (Coturnix coturnix japonica) diet on carcass characteristics and meat quality. The results show a relationship between the type and concentration of ingredients used in diets and carcass characteristics and meat quality. The inclusion of medicinal herbs (thyme, black seed, and mint), plants (canola), seeds (chickpea), spices (cinnamon and coriander), worms (earthworms), bee products (propolis), phytochemicals (lycopene), and edible fungi (common mushrooms) in the diet improved carcass quality characteristics compared to the control diets (basal diets). The inclusion of medicinal herbs (spearmint and green tea), spices (cinnamon), vegetables (tomato), plants (verbena and canola), seeds (marijuana), and edible fungi (oyster mushrooms) improved meat quality. In conclusion, the use of ingredients of natural origin in the diet of Japanese quail improves carcass quality characteristics and meat quality.
Lizbeth Anahı´ Portillo-Torres,Aurea Bernardino-Nicanor,Jose´ Mercado-Monroy,Carlos Alberto Go´mez-Aldapa,Leopoldo Gonza´lez-Cruz,Esmeralda Rangel-Vargas,Javier Castro-Rosas 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.9
To determinate the antimicrobial effect of chloramphenicol and aqueous extract against multidrug-resistant enterohemorrhagic Escherichia coli (EHEC) and Salmonella enterica serovar Typhimurium in CD-1 mice. Aqueous extract was isolated from Hibiscus sabdariffa calyces. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of chloramphenicol and aqueous extract were determined for EHEC and S. Typhimurium. Nine groups of six mice each were formed. Three groups were inoculated orally with 1 × 104 colony-forming units (CFU) of S. Typhimurium, three groups were inoculated with 1 × 104 CFU of EHEC and the remaining three groups were not inoculated. Six hours postinoculation, the mice of some groups were orally administered solutions of aqueous extract (50 mg/mL), chloramphenicol (82 μg/mL), or isotonic saline. The EHEC and S. Typhimurium concentration in all mice feces was determined. For both pathogens, the MIC and MBC values of aqueous extract were 20 y 50 mg/mL, respectively; for chloramphenicol, they were between 17.5 and 82 μg/mL. EHEC and S. Typhimurium were not detected in the feces of mice that were administered aqueous extract on the 2nd and 3rd days posttreatment. Furthermore, these mice recovered from the infection. In contrast, in mice not treated, or treated with chloramphenicol alone, pathogens were isolated from their feces throughout the study, and some mice died. The H. sabdariffa calyx extracts could be an alternative to control multidrug-resistant bacteria in humans and animals.
Norberto Chavarría-Hernández,Eduardo Ortega-Morales,Apolonio Vargas-Torres,Juan-Carlos Chavarría-Hernández,Adriana-Inés Rodríguez-Hernández 한국생물공학회 2010 Biotechnology and Bioprocess Engineering Vol.15 No.4
This study is the first to describe the evolution of both hydrodynamic and oxygen transfer conditions during the submerged culture of the entomopathogenic nematode,Steinernema carpocapsae CABA01 (an indigenous strain isolated within the State of Hidalgo, Mexico), and its symbiotic bacterium, Xenorhabdus nematophila, using an internal-loop mechanically agitated bioreactor of 4.5 L of liquid volume. Concentrations up to 217,306 viable nematodes per mL, with 94% in infective juvenile (IJ) stage (i.e.,204,444 IJ/mL), were achieved in 16 days of bioprocess. The Reynolds number (Re) was used as an index of the actual hydrodynamic conditions, and it varied within the interval 5,150 < Re (dimensionless) < 9,440, involving apparent culture broth viscosity changes from 3 to 5.4 mPa s during the processing. The aeration efficiency was expressed on the basis of the volumetric oxygen transfer coefficient, kLa, which varied within the range 0.026 to 0.170 s−1.
Luis Humberto Delgado-Rangel,Julia Hernández-Vargas,Marymar Becerra-González,Ataúlfo Martínez-Torres,Evgen Prokhorov,J. Betzabe González Campos 한국섬유공학회 2019 Fibers and polymers Vol.20 No.12
The combination of collagen (CG), chondroitin sulfate (CS), and hyaluronic acid (HA) with poly(vinyl alcohol)(PVA) was explored to produce 3D tri-component scaffolds with enhanced mechanical properties and potential use in tissueengineering. The CG/PVA/CS and CG/PVA/HA electrospun scaffolds were crosslinked with citric acid, a cytocompatiblecrosslinker, which induced improved mechanical properties in both dry and wet state, especially with large elongation atbreak in the wet state. Ultimate tensile stress under the dry and wet state are significantly higher than those previouslyreported about collagen based nanofibers. IR, DSC and dielectric analysis demonstrated homogenous blending without phaseseparation and strong interactions between components. All scaffolds had swelling pH-sensitive behavior, making thempromising materials for drug delivery systems. The nanofiber mats permitted adhesion and proliferation of human embryonickidney cells; this cell line formed clusters that adapted well to the mats’ surface, through which the cells extended theirprocesses.
Tick-borne rickettsial pathogens in questing ticks, removed from humans and animals in Mexico
Carolina G. Sosa-Gutierrez,Margarita Vargas-Sandoval,Javier Torres,Guadalupe Gordillo-Pérez 대한수의학회 2016 Journal of Veterinary Science Vol.17 No.3
Tick-borne rickettsial diseases (TBRD) are commonly encountered in medical and veterinary clinical settings. The control of these diseases is difficult, requiring disruption of a complex transmission chain involving a vertebrate host and ticks. The geographical distribution of the diseases is related to distribution of the vector, which is an indicator of risk for the population. A total of 1,107 ticks were collected by tick dragging from forests, ecotourism parks and hosts at 101 sites in 22 of the 32 states of Mexico. Collected ticks were placed in 1.5 mL cryovials containing 70% ethanol and were identified to species. Ticks were pooled according to location/host of collection, date of collection, sex, and stage of development. A total of 51 ticks were assayed by polymerase chain reaction (PCR) to confirm species identification using morphological methods. A total of 477 pools of ticks were assayed using PCR techniques for selected tick-borne pathogens. Anaplasma phagocytophilum was the most commonly detected pathogen (45 pools), followed by, Ehrlichia (E.) canis (42), Rickettsia (R.) rickettsii (11), E. chaffeensis (8), and R. amblyommii (1). Rhipicephalus sanguineus was the tick most frequently positive for selected pathogens. Overall, our results indicate that potential tick vectors positive for rickettsial pathogens are distributed throughout the area surveyed in Mexico.
Are Tattoos an Indicator of Severity of Non-Suicidal Self-Injury Behavior in Adolescents?
Marco Antonio Solís-Bravo,Yassel Flores-Rodríguez,Liliana Guadalupe Tapia-Guillen,Aymara Gatica-Hernández,Miriam Guzmán-Reséndiz,Luis Alberto Salinas-Torres,Tania Lucila Vargas-Rizo,Lilia Albores-Gall 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.7
Objective To compare adolescents with non-suicidal self-injury behavior and tattoos [NSSI (T+)] with another group with non-suicidal self-injury behavior without tattoos [NSSI (T-)]. Methods Adolescents (n=438) 42.6% males from the community (M=12.3, SD=1.3), completed the Self-Injury Schedule. Results The lifetime prevalence of tattoos performed with the purpose to feel pain was 1.8%. Compared to the NSSI (T-) group, the NSSI (T+) group was significantly more likely to meet the DSM-5 frequency criteria of 5 self-injury events in 1 year, practice more than one method of self-injury, and topography, more suicidal intentionality, more negative thoughts and affective emotions before, during, and after self-injury and more academic and social dysfunction. Conclusion Adolescents from the community who practice tattooing to feel pain, show a distinct phenotype of NSSI. Health professionals and pediatricians should assess tattooing characteristics such as intention (to feel pain), frequency, and presence of non-suicidal self-injury behavior and suicide intentionality.