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      • 구강내 악성흑색종에 대한 임상연구

        김욱규,허진호,황대석,김용덕,신상훈,김종렬,정인교 부산대학교 병원 암연구소 2008 부산대병원학술지 Vol.- No.23

        The prognosis of oral malignant melanoma is poor compared with cutaneous melanoma. It may be related to the difficulty of wide enough resection, the early hematogenous matastases, higher stage at initial diagnosis, tendency to growth vertically. In the view of histological differences between oral mucosa and skin, it is impossible use Clark’s and Breslow’s classifications for prognosis. The great problem is that there is still no consensus on the treatment due to rarity. Because data collection from case reports is considered to be the best source of information and should be pooled to anlalyze key determinants of outcome, We reported on 6 cases of primary malignant melanoma of the oral cavity which were diagnosed and treated in Pusan National University Hospital recently and reviewed the literature. Immunohistochemical study on S100 Protein, GP 100 (HMB-45) with biopsy was usable to confirm the melanoma. Neck dissection including wide excision is recommended if lymph node involvement is suspected. Additionally, adjuvant chemotherapy could be supporting therapy.

      • KCI등재

        충남지역 외국인투자유치 촉진전략에 관한 연구

        김억헌 한국생산성학회 1999 生産性論集 Vol.13 No.3

        Foreign Direct Investment(FDI) has been considered as one of the most significant measures to conquer the IMF era of Korean economy. Because of the many obstacles such as government regulations, high wages and rents, etc., FDI into Korea has been unsatisfactory and not enough. The purpose of this study is to develop appropriate strategies to expedite and induce FDI into Choongchungnam-Do(Choongnam). First, the study defines FDI and discuss various sorts of FDI. Second, the study examines the recent states of Choongnam economy. Third, it looks through the current FDI inducements of Choongnam. Finally, this study suggests various strategies to induce FDI into Choongnam.

      • 損害保險料率 算定時 投資收益의 考慮에 關한 硏究

        金億憲 홍익대학교 산업기술연구소 1994 産業技術 Vol.3 No.-

        One characteristic of property and liability insurance companies is that the excess assets, namely the policy reserves and investment income are very important in managing the companies. In that both policy reserves and investment income come from premium prepayment of the policyholders, the question of "whom the investment income belongs to" has been intensively debated especially in the U.S. The purpose of this paper is to rigorously examine Fairley's model which is reasonable theoretically and easy to be applied in considering investment income when setting property and liability insurance premium rates. Besides, the Hill's model and the model of Kraus and Ross are briefly discussed. In the conclusion part, the prerequisites to applying the Fairley's model to Korean property and liability insurance industry are discussed.

      • 하악과두에 발생하는 골연골종의 진단학적 방법

        신상훈,차승만,황대석,김용덕,김욱규 부산대학교 병원 암연구소 2006 부산대병원학술지 Vol.- No.20

        Pulpose : Osteeochondroma is a common benign tumor of the axial skeleton, especially the distal metaphysis of the femur and the proximal metaphysis of the tibia, however, is\ occured rarely on the facial skeleton. Tumors of the mandibular condyle are various and rare. so common interest is a little and its clinical symptoms are similar to the others. therefore, early diagnosis is very difficult. In this study, we will present our cases and review the literatures. Patients and Methods: We studied 17 patients(8 males, 9 females) who were diagnosed a osteochondroma of the mandibular condyle in the department of oral and maxillofacial surgery, Pusan National University Hospital. We reviewed the medical records. Results : Patients' mean age was 30.05 years. The sexual distribution is almost same. Twelve left condyles and five right condyles were involeved. The main symptoms was noise and facial asymmetry. Conclusion : Osteeochondroma is a rare benign tumor of the mandibular condyle. The differential diagnosis is difficult. However, using CT and MRI, we diagnosed early the osteochondroma and treated properly. Thus, we presented the cases of the osteochondroma with the literature reviews.

      • 응급실을 내원한 구강악안면외과 안면골 골절 환자의 변화에 대한 비교 연구

        신상훈,성화식,강영훈,황대석,김용덕,김욱규,김종렬,정인교 부산대학교 병원 암연구소 2008 부산대병원학술지 Vol.- No.24

        Although there have been many clinical studies about the facial trauma in the recent as well as in the past, severity and frequency of facial trauma are reported multifarious. It seemed to be because of variety of social, cultural, and environmental factors, and the view point of investigators. In this study, we investigated about the patients visiting emergency room during recent 4 years(2004-2007), and compared with retrospective study during former 10 years(1992-1996, 1999-2003) in Dept. OMS Pusan National University Hospital. We assessed the cause, type, demographic, etc, and analyzed alterations of facial bone fractures during past 3 periods. The results were as follows. The total number of patients was increased. 429 patients treated for maxillofacial fractures between January 1992 and December 1996, 466 patients treated between January 1992 and December 1996 and 764 patients treated between January 2004 and December 2007. The male-to-female ratio were 4.6:1, 3.9:1, and 4.16:1, respectively. Patient in the age groups of 10-19 years and 20-29 years increased in the latter two periods. Assaults and falls are decreased gradually, but slip down s are increased. Traffic accidents are still major cause of facial trauma. The mandibular fractures showed the highest incidence thorought three periods. Symphysis fractures of mandible was increased and condyle fractures of mandible was drecreased in the third period.

      • 하악측두관절에서 퇴행성 관절염의 실험모델 개발

        신상훈,송동석,김철훈,황대석,김용덕,김욱규 부산대학교 병원 암연구소 2007 부산대병원학술지 Vol.- No.21

        Purpose : The purpose of this study is to investigate temporomandibular joint arthritis that was induced by intra-articular injection of collagenase in rabbits. Material and Methods: In this study, 12 rabbis was used. We injected collagenase on temporomandibular joint of rabbit and observed for six weeks. H-E stain was done. Results : Four weeks later from 2.0 mg collagenase injection, we observe histologic appearance like arthritis. Conclusion : In our study using injection of collagenase in temporomandibular joint of rabbit we produce arthritis on temporomandibular joint of rabbit.

      • KCI등재

        지방자치제단체의 외국인직접투자환경 개선방안

        김억헌 韓日經商學會 2000 韓日經商論集 Vol.19 No.-

        Foreign Direct Investment(FDI) has been considered one of the most important measures to conquer the IMF era of Korean economy. Even though Korean government has tried various means to induce FDI, FDI inflows into Korea have decreased dramatically during January and February of 1999 probably due to the delay of reform by Korean major firms. The propose of this study is to analyze the current problems relating to inducement of FDI. Specifically, this study examines the strategies to improve the FDI environment of self-governed local districts in Korea. First, the study surveys the recent statistics and trends of FDI into Korea. Second, the study examines the obstacles to interfere FDI inflows into self-government local districts. Finally, the study suggests various stategies to improve the FDI environment of self-governed districts in Korea. The suggested strategies are : putting related infra-structure in good order, strengthening administrative independence of self-governed local districts, fostering the small-size firms located in local areas, making good relationships with foreign government organizations in Korea, and improving tax incentive system.

      • 구강내 결손부에 적용된 연조직 재건술식들에 대한 임상적 고찰

        김욱규,이승환,황대석,김용덕,신상훈,김종렬,정인교 부산대학교 병원 암연구소 2007 부산대병원학술지 Vol.- No.21

        To evaluate criteria, indications, and prognosis of the various reconstructive methods on the patients with intraoral soft tissue defect who had been treated at Dept. of Oral and Maxillofacial Surgery, Pusan National University Hospital from 2003 to 2005, we have reviewed the clinical data of the patients and analysed. The results were as follows: 1. Tongue flaps have been mainly applied on anterior portion of palate and maxilla. The survival rate was high percent, but the cooperation of patient was inevitable for the success. 2. Palatal mucosa rotational flaps were available on relative large defect on palate, oroantral fistula site. The side effect was a scaring band from secondary healing on denuded donor palate site. Sometimes the band came to be a hinderance to swallowing, phonation. 3. The application of free skin graft on entire maxilla site , palate was possible. The skin from thigh, abdomen could be applicable on fixed or movable tissues. The advantages of abdominal skin were easy harvest and direct donor site closure. 4. Forearm free flap was a workhorse flap for everywhere in intraoral defects. We had used the flap on cheek, floor of mouth, tongue without any significant complications. But the application of the flap was required for long operation time, which was disadvantageous to the old, weak patients. 5. Cervical platysmal flap could be easily applicable for buccal cheek, floor of mouth after excision of the cancer lesion. the design of the flap could be made simultaneously on neck dissection, but the danger of cancer remnants on the flap always might be remained. 6. Buccal fat pad pedicled flap must have been a primary flap for repair of oroantral fistula especially on posterior maxilla. The flap survival will be expected if the considerations for above reconstructivε methods on site, size, condition of defects primarily could be made.

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