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림프질 전이가 있는 하인두암과 하부식도암의 진단에 활용된 내시경초음파 유도하 Trucut 생검 1예
광명옥,이정환,문정섭,김유선,류수형,총배천,김형훈,김현태 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-
The incidence of double primary cancer is about 10% in all kinds of cancers. Double primary cancer is usually accompanied by gastrointestinal cancer. Esophageal cancer is supposed to be frequently accompanied by squamous cell carcinoma of the head and neck or the upper respiratory tract, because of such common carcinogens as smoking and alcohol ingestion. Esophageal cancer and hypopharyngeal cancer are usually diagnosed by esophagogastric endoscopy with biopsy. We performed endoscopic ultrasound-guided Trucut biopsy(EUS-TCB) to diagnose a mediastinal mass in a 49 year-old patient, who visited our hospital because of voice change. During procedure, we accidently found enlarged celiac lymph node, and obtained tissue from the mediastinal lymph node and the celiac lymph node. We confirmed double primary cancer of squamous cell carcinoma in the esophagus and the hypopharynx via esophagogastric endoscopy.
( Pei Chuan Tsung ),( Soo Hyung Ryu ),( In Hye Cha ),( Hee Won Cho ),( Jin Nam Kim ),( You Sun Kim ),( Jeong Seop Moon ) 대한간학회 2013 Clinical and Molecular Hepatology(대한간학회지) Vol.19 No.2
Background/Aims: Spontaneous bacterial peritonitis (SBP) has been known to greatly influence the survival rate of patients with liver cirrhosis. However, the factors that affect the survival rate in patients with SBP need to be clarified. Methods: This study enrolled 95 liver cirrhosis patients diagnosed with SBP. The laboratory findings of their serum and ascetic fluid were examined and the characteristics of the isolated microorganisms in their peritoneal fluid were analyzed. Results: The proportion of patients with culture-positive SBP was 41.1%, and 47 microorganisms were isolated from the ascetic fluid. The proportions of cultured bacteria that were Gram negative and Gram positive were 57.4% and 40.4%, respectively. The proportions of Escherichia coli, Klebsiella species, and Streptococcus species were 25.5%, 19.1%, and 19.1%, respectively. Enterococcus species represented 12.8% of the microorganisms cultured. The overall survival rates at 6, 12, and 24 months were 44.5%, 37.4%, and 32.2%, respectively. There was no relationship between the bacterial factors and the survival rate in SBP. Multivariate analysis revealed that the presence of hepatocellular carcinoma (HCC; P=0.001), higher serum bilirubin levels (≥3 mg/dL, P=0.002), a prolonged serum prothrombin time (I.e., international normalized ratio>2.3, p<0.001), renal dysfunction (creatinine >1.3 mg/dL, P<0.001), and lower glucose levels in the ascetic fluid (<50 mg/dL, p<0.001) were independent predictive factors of overall survival rate. Conclusions: HCC, higher serum bilirubin levels, a prolonged serum prothrombin time, renal dysfunction, and lower ascetic glucose levels are associated with higher mortality rates in cirrhotic patients with SBP.
GSEx4 Modulates White Adipose Tissues in High Fat Diet induced Obese Mice
Pei-Chin Tsung,Ki-Hyeon Yoon,Yang-Sam Jung,Hee-Young Lee,Hae-Gyeong Jeong(정해경),Su-Mi Park,Juran Ha,Yeonhee Hong,Seolwha Choi,Dongmin Park,Michung Yoon,Gyeong-Cheol Kim,Soon-Shik Shin 한국실험동물학회 2009 한국실험동물학회 학술발표대회 논문집 Vol.2009 No.-
Tsung Pei-Chi,Sung Soon Ki,Son Dong Wuk,Lee Sang Weon,Song Geun Sung 대한말초신경학회 2019 The Nerve Vol.5 No.1
Objective Diffusion tensor imaging (DTI) was used to study motor function prognosis in stroke and intracerebral hemorrhage (ICH) patients. In this study, we investigated the correlation between DTI and computed tomography (CT) and compared the predictability of clinical outcome in patients with stoke, ICH, brain tumor, and traumatic brain injury. Methods We retrospectively reviewed 22 patients with brain injury who underwent DTI and CT. Motor weakness was assessed using the Medical Research Council (MRC) grade scores. The fractional anisotropy (FA) of the region of interest (ROI) of DTI was compared between the injured and non-injured sites. Results The differences in the encephalomalacic changes of corticospinal tract injury between DTI and CT were not statistically significant in patients with motor weakness (p=0.09). Neither modality could predict the motor recovery rate (CT, p=0.89; DTI, p=0.86). However, DTI showed a significant difference in initial MRC grade (p=0.003). We evaluated the possibility of more accurate evaluation of MRC grade change using DTI. FA ROI in injured (450.73±105.32) and non-injured (582.18±99.68) sites showed a significant difference (p=0.00). Pearson’s correlation coefficient showed that FA ROI ratio had a significant correlation with initial (p=0.43) and follow-up (p=0.012) MRC grades, but not with MRC grade change (p=0.67). Conclusion DTI is more accurate than CT for evaluating motor deficit. It aids the treatment and rehabilitation plans in patients with brain injury. However, the prediction of motor function recovery is still insufficient.
GGEx16 Reduces Blood Lipid Levels and Adipose Tissues in High Fat Diet Induced Obese Mice
Pei-Chin Tsung,Hae-Gyeong Jeong(정해경),Su-Mi Park,Hee-Young Lee,Juran Ha,Yeonhee Hong,Seolwha Choi,Dongmin Park,Ki-Hyeon Yoon,Yang-Sam Jung,Michung Yoon,Soon-Shik Shin 한국실험동물학회 2009 한국실험동물학회 학술발표대회 논문집 Vol.2009 No.2
( Pei Chuan Tsung ),( Jong Hyeok Park ),( You Sun Kim ),( Sun Young Kim ),( Won Wo Park ),( Hyun Tae Kim ),( Jin Nam Kim ),( Yun Kyung Kang ),( Jeong Seop Moon ) 대한간학회 2013 Gut and Liver Vol.7 No.2
Background/Aims: Mini-probe endoscopic ultrasonography (mEUS) is a useful diagnostic tool for accurate assessment of tumor invasion. The aim of this study was to estimate the accuracy of mEUS in patients with early colorectal cancer (ECC). Methods: Ninety lesions of ECC underwent mEUS for pre-treatment staging. We divided the lesions into either the mucosal group or the submucosal group according to the mEUS findings. The histological results of the specimens were compared with the mEUS findings. Results: The overall accuracy for assessing the depth of tumor invasion (T stage) was 84.4% (76/90). The accuracy of mEUS was significantly lower for submucosal lesions compared to mucosal lesions (p=0.003) and it was lower for large tumors (≥2 cm) (p=0.034). The odds ratios of large tumors and submucosal tumors affecting the accuracy of T staging were 3.46 (95% confidence interval [CI], 1.05 to 11.39) and 6.25 (95% CI, 1.85 to 25.14), respectively. When submucosal tumors were combined with large size, the odds ratio was 14.67 (95% CI, 1.46 to 146.96). Conclusions: The overall accuracy of T stage determination with mEUS was considerably high in patients with ECC; however, the accuracy decreased when tumor size was >2 cm or the tumor had invaded the submucosal layer. (Gut Liver 2013;7:163-168)
Advanced Imaging of Nanometer-Scale Recorded Bits on Super-Resolution Near-Field Optical Disk
Pei Lin Yang,Din Ping Tsai,Cheng Wei Lin,Chih Ching Hsu,Pei Hsin Chang,Tsung Sheng Kao,Wei Chih Lin 한국물리학회 2005 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.47 No.1
An advanced imaging technique is demonstrated for fast, non-destructive and high resolution characterizations for nanometer-scale recorded bits on a super-resolution near-field optical disk (super-RENS). For the first time, an array of individual 100 nm recorded marks is imaged and studied by using the conductive-atomic force microscopy (C-AFM) method. Discussions also include comparisons of 300 nm, 200 nm and 100 nm recorded marks on both a super-RENS disk and a commercial DVD disk, and the image results are evidence of the high carrier-to-noise ratio (CNR) value on the super-RENS disk, even though the mark size has been shrunk to less than the diffraction limit.
A case of giant left atrial myxoma presenting with severe mitral valve obstructive symptoms
Chuan, Tsung-Pei,Sir, Jung-Ju,Park, Il-Kwon,Park, Young-Il,Kim, Hyun-Tae,Park, Kyung-Jun,Min, Seon-Kyung,Kim, Yong-In,Cho, Wook-Hyun,Choi, Suk-Koo 인제대학교 2008 仁濟醫學 Vol.29 No.-
심장 내 점액종은 매우 드문 질환이다. 본 증례는 지속적으로 악화되는 양상의 호흡 곤란을 주소로 내원한 35세 남자에서 심장 초음파 검사 상 좌심방 내 거대 심장내 종괴가 발견되어 입원 후 개흉 수술로 종괴를 제거하였으며 조직 검사상 점액종으로 확진된 증례이다. 심장 초음파 소견 상 종괴는 매우 유동적으로 심실 이완기에 승모판막 입구를 폐쇄하여 유입 혈류를 제한하는 양상이었다. 수술 후 환자는 증상이 호전되어 퇴원하였다.
Tsung-Yeh Wu,Po-Cheng Tsai,Shu-Cheng Lo,Yi-Ru Li,Kuang-Li Lee,Sen-Yeu Yang,Pei-Kuen Wei 한국물리학회 2018 Current Applied Physics Vol.18 No.1
We developed dielectric heating-assisted nanoimprint method for rapid fabrication of ultraflexible nanostructures. Using spin-coating polyvinyl-chloride (PVC) film on the glass slide, the dielectric heating on PVC film helped the pattern transfer from the mold to PVC film in few seconds. Various kinds of nanostructures were successfully made on PVC films with about 20-mm thickness. We demonstrated the applications of ultraflexible metallic nanostructures for bending measurement using surface plasmon resonance (SPR) and surface enhanced Raman scattering (SERS) on the curved surfaces. For measuring bending angles using SPR on capped nanowire arrays, the minimum detection angle was 2.4 103 degree under 0.02 nm wavelength resolution. For SERS measurement, the nanorod arrays on a curved substrate can increase SERS signals for two times as compared to planar SERS substrate.