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Lee, Hae-Young,Choi, Bong-Hwan,Lee, Jung-Sim,Jang, Gul-Won,Lee, Kyung-Tai,Chung, Ho-Young,Jeon, Jin-Tea,Cho, Byung-Wook,Lee, Jun-Heon,Kim, Tae-Hun Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.5
AMP-activated protein kinase alpha 2 (PRKAA2) plays a key role in regulation of fatty acid and cholesterol metabolism. This study investigated the porcine PRKAA2 gene as a positional candidate for intramuscular fat and backfat thickness traits in pig chromosome 6. A partial fragment of the porcine PRKAA2 gene, amplified by PCR, contained a putative intron 3 including a part of exon 3 and 4, comparable with that of human PRKAA2 gene. Within the fragment, several single nucleotide polymorphisms were identified using multiple sequence alignments. Of these, TaqI restriction enzyme polymorphism was used for genotyping various pig breeds including Korean reference family. Using linkage and physical mapping, the porcine PRKAA2 gene was mapped in the region between microsatellite markers SW1881 and SW1680 on chromosome 6. Allele frequencies were quite different among pig breeds. The full length cDNA of the porcine PRKAA2 (2,145 bp) obtained by RACE containing 1,656 bp open reading frame of deduced 552 amino acids, had sequence identities with PRKAA2 of human (98.2%), rat (97.8%), and mouse (97.5%). These results suggested that the porcine PRKAA2 is a positional candidate gene for fat deposition trait at near telomeric region of the long arm of SSC 6.
일측 Arnold - Chiari Malformation 을 동반한 쌍태 임신에서 임신 중반기 선택적 유산 1 예
이상헌(Sang Hun Lee),박성호(Sung Ho Park),박기한(Ki Han Park),조현진(Hyun Jin Cho),정태범(Tea Bum Chung),전현아(Hyun Ah Jun),이근영(Keun Young Lee) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.11
A 38-year-old woman with twin pregnancy was referred after detection of hydrocephalus in one fetus at 23+1 weeks` gestation. Sonography showed hydrocephalus, a scalloping of the frontal bone giving a lemon-like configuration, and meningocele. The affected twin was terminated by ultrasonographically guided intracardiac injection of 4 ml (8 mEq/L) potassium chloride solution at 24+5 weeks` gestation. Chromosomal analysis of the other fetus showed normal findings (46, XX). Serial ultrasound scans and coagulopathy tests were unremarkable. Preterm premature rupture of the membrane was developed at 33+3 weeks` gestation, and emergency Cesarian section was done. A healthy 1360 g female was born, with Apgar scores of 7 and 8 at one and five minutes, respectively.
A 90-Day Repeated Oral Dose Toxicity Study of Alismatis Rhizoma Aqueous Extract in Rats
Lee, Mu-Jin,Jung, Ho-Kyung,Lee, Ki-Ho,Jang, Ji-Hun,Sim, Mi-Ok,Seong, Tea-Gyeong,Ahn, Byung-Kwan,Shon, Jin-Han,Ham, Seong-Ho,Cho, Hyun-Woo,Kim, Yong-Min,Park, Sung-Jin,Yoon, Ji-Young,Ko, Je-Won,Kim, Jo Korean Society of ToxicologyKorea Environmental Mu 2019 Toxicological Research Vol.35 No.2
Alismatis rhizoma (AR), the dried rhizome of Alisma orientale (Sam.) Juzep, is a well-known, traditional medicine that is used for the various biological activities including as a diuretic, to lower cholesterol and as an anti-inflammatory agent. The present study was carried out to investigate the potential toxicity of the Alismatis rhizoma aqueous extract (ARAE) following 90-day repeated oral administration to Sprague-Dawley rats. ARAE was administered orally to male and female rats for 90 days at 0 (control), 500, 1,000 and 2,000 mg/kg/day (n = 10 for male and female rats for each dose). Additional recovery groups from the control group and high dose group were observed for a 28-day recovery period. Chromatograms of ARAE detected main compounds with four peaks. Treatment-related effects including an increase in the red blood cells, hemoglobin, hematocrit, albumin, total protein, and urine volume were observed in males of the 2,000 mg/kg/day group (p < 0.05). However, the diuretic effect of ARAE was considered, a major cause of hematological and serum biochemical changes. The oral no-observed-adverse-effect level (NOAEL) of the ARAE was > 2,000 mg/kg/day in both genders, and no target organs were identified.
가교제의 종류가 천연고무 발포체의 팽윤거동에 미치는 효과
이환광(Lee, Hwan-Kwang),정태경(Chung, Tea-Kyung),김성찬(Kim, Sung-Chan),김현기(Kim, Hyun-Gi),최경만(Choi, Kyung-Man),김영민(Kim, Young-Min),한동훈(Han, Dong-Hun) 한국산학기술학회 2008 한국산학기술학회논문지 Vol.9 No.6
가교제의 종류가 헬리콥터 연료탱크의 자기밀폐층 소재로 적용시키기 위한 천연고무 스폰지의 팽윤에 미치는 효과를 조사하였다. 과산화물과 황을 섞은 가교방식과 과산화물에 의한 가교방식을 채택하였다. 천연고무 콤파운드들 Kneader와 Roll-Mill을 활용하여 제조하고, 고압조건의 프레스에서 부분 가교시킨 후 대기압의 금형에서 발포와 완전가교를 실시하였다. 얻어진 스폰지의 겉보기밀도를 측정하고 스폰지의 셀구조를 주사전자현미경을 통하여 관찰하였다. 톨루엔, 이소옥탄과 항공유를 사용하여 실온에서 팽윤실험을 실시하였다. 용매에 2분 동안 침적 후 얻어지는 부피팽윤비 값은 과산화물 가교에 의한 천연고무 스폰지가 비슷한 양의 황과 과신화물의 혼합가교에 의한 경우보다 높았다. 스폰지의 겉보기밀도와 셀구조는 과산화물 함량에 매우 민감하였으며 이는 또한 천연고무 스폰지의 팽윤거동에 영향을 마쳤다. 천연고무 스폰지가 연료와 접촉하여 신속한 팽윤이 얻어지기 위하여 금형에서 동시에 발생하는 두 가지 반응인 발포제의 분해반응과 천연고무의 가교반응을 적절히 조절하는 것이 중요하다. The effects of the type of curing agent on the swelling of the natural rubber(NR) sponge applicable to the self-sealing layer of a helicopter fuel tank were investigated. The curing systems employed were peroxide and mixed ones of sulfur and peroxide. The NR compounds were prepared in a kneader and a roll-mill. The compounds were partially cured in a press at high pressure and subsequently cured fully with expansion in another press at atmospheric pressure. The apparent density of the NR sponge was measured and the cell structure was observed with scanning electron microscopy. The swelling experiments were performed at room temperature using toluene, iso-octane, and an aircraft fuel as a solvent. More rapid volume swelling of the NR sponge cured by peroxide was achieved than cured by sulfur and peroxide with similar amount of curing agent added in rubber compounds. The apparent density and cell structure of the sponge were extremely sensitive to the amount of peroxide, which influences again the swelling behavior of the NR sponge. It is important to control properly two reactions of decomposition of foaming agent and crosslinking of NR in the mold to obtain rapid swelling of the NR sponge on contact of the fuel.
한태희(Tea-hee Han),조용선(Yong-Sun Cho),박형민(Hyoung-Min Park),이나영(Na-Young Lee),남긍현(Goung-Hyun Nam),최효상(Hyo-Sang Choi),임성훈(Sung-Hun Lim),정동철(Dong-Chul Chung) 한국조명·전기설비학회 2006 한국조명·전기설비학회 학술대회논문집 Vol.2006 No.11월
The flux-lock type superconducting fault current limiter (SFCL) can be divided into the subtractive polarity winding and additive polarity winding according to the winding between the coil 1 and coil 2. We investigated quench and recovery characteristics of flux-lock type SFCL The quench time and recovery time for the superconductivity in the subtractive polarity winding became longer that of additive polarity winding under the same conditions. The quench and recovery characteristics of a superconducting element in the flux-lock type SFCL were dependent on winding direction.