「災難」という思考に潜む日本的「安全」認識

Takeshi Kaneko 계명대학교 국제학연구소 2012 국제학논총 Vol.17 No.-

The purpose of this paper is to show a way how Japanese people have recognized some conditions as “Disaster”, in order to set up an idea of “safety-first” as an important global standard. The modern idea of “safety-first” was received through a “cultural hybridity” mediated by Confucian ethic, and in such a process the idea has been practiced depending on a Charity of which subject is limited to be a range of a self-concentric circle. There exists a cultural system motivating Japanese people to “guilt” that is always resettable in the base. It is thought to be a factor obstructing the individualism regarding the practice of “safety-first”.

일본신찬을 통한 한국고대식의 추정연구 : 담산신사(談山神社)가길제(嘉吉祭)백미어식(2)

김천호,Kentaro Kaneko,Takeshi Sumino,Takashi Kaneda 한국식생활문화학회 1993 韓國食生活文化學會誌 Vol.8 No.2

談山神社의 前身은 한반도로부터 일본으로 佛敎전래 이후 佛敎文化가 번성하던 7세기에 건립된 妙樂寺이다. 近世에 들어와서 국가적인 廢佛毁釋으로 神社로 바뀌었으므로 古代로부터의 1200년간 절의 佛供양식이 그대로 답습되어 전승되어 왔다. 神饌이라고 하나 실제로는 古代佛敎文化의 원형이라고 볼 수 있다. 문화의 교류가 빈번했던 한국고대의 식문화를 연구하는데 참고가 되리라 본다. 1) 高排 음식의 형태는 本神社와 同時代 同系統의 春日大社나 法隆寺 등 古代의 절이나 神社에 남아 있어서 현존하는 한국 고배차림과 상통하는 점을 뚜렷이 볼 수 있다. 단지 일본은 현재로는 死者나 神에게 대한 제사에만 남아 있다는 점이 한국은 경사스런 행사에도 널리 쓰여지고 있다는 것이 차이점이다. 또 한가지는 本神社의 고배형태가 단순한 圓柱型에서상부가 지붕 같이 넓어지는 형태로 변형된 것이다. 그리고 한반도의 고배음식은 실제로 행사가 끝나면 나누어 먹을 수 있는 음식인데 비해 「百味御食」은 형태만을 화려하게 만든 상징적인 것이다. 이는 시대의 흐름에 따라 외관상의 모양만을 만든 것이라 보고 神人供食의 사상으로 볼 때 古代에는 먹을 수 있는 음식이였을 것이다. 현재 한국의 고배음식은 원래 불교, 도교, 유교, 샤마니즘 등의 복합적인 영향으로 형성된 것으로 보아 인도와 중국에 근원을 두어야 할 것이다. 뒷바침이 될만한 것이 없어서 앞으로 뿌리와 유래 그리고 변천과정 등을 조사해야 할 것이다. 2) 고배음식 위의 장식은 고추나 꽈리 등의 열매를 竹串(대나무 꽂이)에 꽂아서 더욱 화려하게 만든 점이 특징이다. 이는 李朝시대 궁중연회행사에서 고배음식에 床花로 꽂는데 까지의 발전과정에서 극히 시초단계의 형태로 본다. 생열매나 꽃이 보였고 다음이 떡으로 새나 꽃모양을 만들어 장식했고(사진 10) 그 다음이 계절과 관계없이 실크나 종이로 造花를 만들어 화려하게 장식했다. 3) 和稻의 紋樣은 매년 다르나 卍型은 필히 포함시키고 나머지는 다양한 종류중에서 선택한 것으로 보아 문양이 고대로부터 다양하게 발전했었음을 알 수 있고 卍자를 필히 넣는 것은 本神社가 절이였고 절형식의 영향을 크게 받고 있음을 증명해 준다. 4) 荒稻 本 제사에서는 현재의 벼보다 대가 수십센치나 긴 黑, 白, 赤 등 3종류의 古代米를 쓰고 있다. 赤米와 黑米는 玄米의 일종으로서 品種과 系統에 따라서 種皮의 색이 赤色系는 赤米, 黑紫色인 것을 黑米로 칭하여 사용했다. 白米는 현재의 도정된 쌀이라고 본다. 이도 원래는 대가 긴 古代米였다. 春日大社 제사에도 黑米飯이 나오는 것으로 보아 현재의 개량된 쌀이 되기 이전의 형태는 물론 최초에는 현미를 식용했던 점을 알 수 있다. 무엇보다 술이 달린 벼의 대를 그대로 장식한 것이 특이하다. 이는 쌀을 귀중한 식량으로 꼽았던 것으로 본다. 5) 果實御供의 과일은 각종 야생열매라고 보는 것이 타당하다. 현재 우리가 식용하지 않는 과일, 채소, 구근류가 보인다. 古代食用식물의 재연구조사가 필요하다. 6) 古代제사나 현재 고배음식에서 보이는 五色은 五行說에 근거를 두나 古代 신앙부터 다수의 종교의 부합적인 사상에 의하여 형성된 것으로 본다. The predeccessor of Danjanjinja was Myorak temple which is built in the 7th century. At that age, the Buddhist culture of Japan had highly prospected by transmitting Buddhism to Japan from Han peninsular On the other hand, the private god of Fujiwara family in Danjanjinja is Uchigami which is one of typical Japanese popular belief like Dangshin of Korean's. Through these historical background, it could by presumed that the Kakitsisai might be the original form of Korean Buddhist sacrificial offerings from ancient age. So this study on Kakitsisai what had handed down from generation to generation about for 1300 years help us to study and estimate the ancient dietary culture of Korean and Japanese. 1. Kakitsisai performed high filling method in the sacrificial offerings like Kasuga, Horyuji and Korea. 2. The patterns and colors of high filling offerings are various in Korea and Japan. 3. They used unpolished rice by ancient rice, and called red and black one. We can guess both of countries ate unpolished rice at that age. 4. They used many kind of ancient wild fruits and vegetables. We could recognize what the ancients had eaten the foods.

Inhibition of ENNG-Induced Pyloric Stomach and Small Intestinal Carcinogenesis in Mice by High Temperature- and Pressure-Treated Garlic

Kaneko, Takaaki,Shimpo, Kan,Chihara, Takeshi,Beppu, Hidehiko,Tomatsu, Akiko,Shinzato, Masanori,Yanagida, Takamasa,Ieike, Tsutomu,Sonoda, Shigeru,Futamura, Akihiko,Ito, Akihiro,Higashiguchi, Takashi Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

High temperature- and pressure-treated garlic (HTPG) has been shown to have enhanced antioxidative activity and polyphenol contents. Previously, we reported that HTPG inhibited 1,2-dimethylhydrazine-induced mucin depleted foci (premalignant lesions) and $O^6$-methylguanine DNA adduct formation in the rat colorectum. In the present study, we investigated the modifying effects of HTPG on N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG)-induced pyloric stomach and small intestinal carcinogenesis in mice. Male C57BL/6 mice were given ENNG (100 mg/l) in drinking water for the first 4 weeks, then a basal diet or diet containing 2% or 5% HTPG for 30 weeks. The incidence and multiplicity of pyloric stomach and small intestinal (duodenal and jejunal) tumors in the 2% HTPG group (but not in the 5% HTPG group) were significantly lower than those in the control group. Cell proliferation of normal-appearing duodenal mucosa was assessed by MIB-5 immunohistochemistry and shown to be significantly lower with 2% HTPG (but again not 5% HTPG) than in controls. These results in dicate that HTPG, at 2% in the diet, inhibited ENNG-induced pyloric stomach and small intestinal (especially duodenal) tumorigenesis in mice, associated with suppression of cell proliferation.

Inhibition of Azoxymethane-induced Colorectal Aberrant Crypt Foci in Mice Fed a High-fat Diet by Pleurotus eryngii (Eringi) and Hypsizygus marmoreus (Bunashimeji)

Kaneko, Takaaki,Chihara, Takeshi,Shimpo, Kan,Beppu, Hidehiko,Higashiguchi, Takashi,Sonoda, Shigeru Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Obesity markedly increases the risk of colorectal cancer. Recently, the preventive effects of edible mushrooms on triglyceride elevation and visceral fat accumulation have been reported. Here, the effects of Pleurotus eryngii (Eringi) and Hypsizygus marmoreus (Bunashimeji) on azoxymethane (AOM)-induced aberrant crypt foci (ACF; precancerous lesions) in the colorectums of mice fed a high-fat diet were examined. Eringi (ER) and Bunashimeji (BU) mushroom powder samples were used. Six-week-old male C57BL/6J mice received an intraperitoneal injection of AOM (10 mg/kg) once a week for two weeks, and were sacrificed and dissected at 6 weeks after the start of the experiment. After the initiation of the experiment, they received a normal diet (ND), high-fat diet (HFD), HFD + ER (1 or 5% of diet), or HFD + BU (1 or 5% of diet). As a result, body and fat weights were significantly lower in the 5% ER and BU groups than in the HFD group. Liver triglyceride levels were also significantly lower in the 5% ER and BU groups. Total liver cholesterol levels were significantly lower in the 5% ER group. The numbers of ACF (especially large ACF) showed strong inhibitory effects in both ER and BU groups. Measurement of the cell proliferation marker Ki-67 labeling index in the colonic mucosa demonstrated more significant suppression in both ER and BU groups than in the HFD group. These results suggest that the simultaneous intake of ER and BU may inhibit colorectal tumorigenesis in HFD-fed mice.

Cobalt-doped nickel oxide nanoparticles as efficient hole transport materials for low-temperature processed perovskite solar cells

Kaneko, Ryuji,Chowdhury, Towhid H.,Wu, Guohua,Kayesh, Md. Emrul,Kazaoui, Said,Sugawa, Kosuke,Lee, Jae-Joon,Noda, Takeshi,Islam, Ashraful,Otsuki, Joe Elsevier 2019 SOLAR ENERGY -PHOENIX ARIZONA THEN NEW YORK- Vol.181 No.-

<P><B>Abstract</B></P> <P>We have synthesized cobalt-doped NiO<I> <SUB>x</SUB> </I> nanoparticles containing 0.5, 1, 2, 5 and 10 mol% cobalt ions and have investigated their electronic properties, which can be processed into smooth and pinhole-free layers at low temperature (<150 °C) as hole transport layers (HTLs) for perovskite solar cells (PSCs). We have revealed that the relationship between conductivity of HTLs and hole extraction properties to improve the photovoltaic performance. The thin film of cobalt-doped NiO<I> <SUB>x</SUB> </I> nanoparticles showed higher conductivities compared to pristine NiO<I> <SUB>x</SUB> </I> nanoparticles. Consequently, PSCs with power conversion efficiencies over 14.5%, an improvement from 11.5% for those with the pristine NiO<I> <SUB>x</SUB> </I>-based HTL, have been obtained. This work will contribute to the development of doped metal oxide HTLs, which are processable at low temperature.</P> <P><B>Highlights</B></P> <P> <UL> <LI> NiO<I> <SUB>x</SUB> </I> nanoparticles with different concertation of cobalt ions are synthesized. </LI> <LI> Co-NiO<I> <SUB>x</SUB> </I> layers are fabricated at low-temperature process as a hole transport layer. </LI> <LI> The band alignment is optimized by decreased work function of Co-NiO<I> <SUB>x</SUB> </I> layer. </LI> <LI> The conductivity of Co-NiO<I> <SUB>x</SUB> </I> films is improved to 6.20 × <SUP> 10 - 6 </SUP> S <SUP> c m - 1 </SUP> . </LI> <LI> Conversion efficiency is improved to 14.5% using 1 mol% Co-NiO<I> <SUB>x</SUB> </I>. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Effects of Aloe-emodin and Emodin on Proliferation of the MKN45 Human Gastric Cancer Cell Line

Chihara, Takeshi,Shimpo, Kan,Beppu, Hidehiko,Yamamoto, Naoki,Kaneko, Takaaki,Wakamatsu, Kazumasa,Sonoda, Shigeru Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Aloe-emodin (1, 8-dihydroxy-3-hydroxyl-methylanthraquinone; AE) and emodin (1,3,8-trihydroxy-6-methylanthraquinone; EM) are anthraquinone derivatives that have been detected in some medical plants and share similar anthraquinone structures. AE and EM have been shown to exhibit anticancer activities in various cancer cell lines; however, the inhibitory effects of these derivatives on the growth of cancer cells were previously reported to be different. Gastric cancer is the second most common cause of cancer cell death worldwide. In the present study, we examined the inhibitory effects of 0.05 mM AE and 0.05 mM EM on the proliferation of the MKN45 human gastric cancer cell line. The proliferation of MKN45 cells was significantly inhibited in AE- and EM-treated groups 24 h and 48 h after treatment. Furthermore, the inhibitory effects of EM were stronger than those of AE. The cell cycle of MKN45 cells were arrested in G0/G1 phase or G0/G1 and G2/M phases by AE and EM, respectively. However, an analysis of intracellular polyamine levels and DNA fragmentation revealed that the mechanisms underlying cell death following cell arrest induced by AE and EM differed.

Successful Use of an eSheath for Failed Introduction of the Evolut R Valve during Transfemoral Transcatheter Aortic Valve Implantation

Umihiko Kaneko,Ken Kobayashi,Daisuke Hachinohe,Keijiro Mitsube,Azusa Furugen,Takeshi Kawamura,Ryuji Koshima,Tsutomu Fujita 대한심장학회 2020 Korean Circulation Journal Vol.50 No.4

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Reduction of Intestinal Polyp Formation in Min Mice Fed a High-Fat Diet with Aloe Vera Gel Extract

Chihara, Takeshi,Shimpo, Kan,Beppu, Hidehiko,Tomatsu, Akiko,Kaneko, Takaaki,Tanaka, Miyuki,Yamada, Muneo,Abe, Fumiaki,Sonoda, Shigeru Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7

Aloe vera gel supercritical $CO_2$ extract (AVGE) has been shown to contain five phytosterols, reduce visceral fat accumulation, and influence the metabolism of glucose and lipids in animal model experiments. Recent epidemiologic studies have shown that obesity is an established risk factor for several cancers including colorectal cancer. Therefore, we examined the effects of AVGE on intestinal polyp formation in Apc-deficient Min mice fed a high-fat diet. Male Min mice were divided into normal diet (ND), high fat diet (HFD), low dose AVGE (HFD+LAVGE) and high dose AVGE (HFD+HAVGE) groups. The ND group received AIN-93G diet and the latter 3 groups were given modified high-fat AIN-93G diet (HFD) for 7 weeks. AVGE was suspended in 0.5% carboxymethyl cellulose (CMC) and administered orally to mice in HFD+LAVGE and HFD+HAVGE groups every day (except on Sunday) for 7 weeks at a dose of 3.75 and 12.5 mg/kg body weight, respectively. ND and HFD groups received 0.5% CMC alone. Between weeks 4 and 7, body weights in the HFD and HFD+LAVGE groups were reduced more than those in the ND group. However, body weights were not reduced in the HFD+HAVGE group. Mice were sacrificed at the end of the experiment and their intestines were scored for polyps. No significant differences were observed in either the incidence and multiplicity of intestinal polyps (${\geq}0.5$ mm in a diameter) among the three groups fed HFD. However, when intestinal polyps were categorized by their size into 0.5-1.4, 1.5-2.4, or ${\geq}2.5$ mm, the incidence and multiplicity of large polyps (${\geq}2.5$ mm) in the intestine in the HFD+HAVGE group were significantly lower than those in the HFD group. We measured plasma lipid (triglycerides and total cholesterol) and adipocytokine [interleukin-6 and high molecular weight (HMW) adiponectin] levels as possible indicators of mechanisms of inhibition. The results showed that HMW adiponectin levels in the HFD group were significantly lower than those in the ND group. However, the levels in the HFD+HAVGE group were significantly higher than those in the HFD group. These results indicate that HAVGE reduced large-sized intestinal polyps and ameliorated reduction in plasma HMW adiponectin levels in Min mice fed HFD.

Dietary Aloe Vera Gel Powder and Extract Inhibit Azoxymethane-induced Colorectal Aberrant Crypt Foci in Mice Fed a High-fat Diet

Chihara, Takeshi,Shimpo, Kan,Kaneko, Takaaki,Beppu, Hidehiko,Higashiguchi, Takashi,Sonoda, Shigeru,Tanaka, Miyuki,Yamada, Muneo,Abe, Fumiaki Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2

Aloe vera gel exhibits protective effects against insulin resistance as well as lipid-lowering and anti-diabetic effects. The anti-diabetic compounds in this gel were identified as Aloe-sterols. Aloe vera gel extract (AVGE) containing Aloe-sterols has recently been produced using a new procedure. We previously reported that AVGE reduced large-sized intestinal polyps in Apc-deficient Min mice fed a high fat diet (HFD), suggesting that Aloe vera gel may protect against colorectal cancer. In the present study, we examined the effects of Aloe vera gel powder (AVGP) and AVGE on azoxymethane-induced colorectal preneoplastic aberrant crypt foci (ACF) in mice fed a HFD. Male C57BL/6J mice were given a normal diet (ND), HFD, HFD containing 0.5% carboxymethyl cellulose solution, which was used as a solvent for AVGE (HFDC), HFD containing 3% or 1% AVGP, and HFDC containing 0.0125% (H-) or 0.00375% (L-) AVGE. The number of ACF was significantly lower in mice given 3% AVGP and H-AVGE than in those given HFD or HFDC alone. Moreover, 3% AVGP, H-AVGE and L-AVGE significantly decreased the mean Ki-67 labeling index, assessed as a measure of cell proliferation in the colonic mucosa. In addition, hepatic phase II enzyme glutathione S-transferase mRNA levels were higher in the H-AVGE group than in the HFDC group. These results suggest that both AVGP and AVGE may have chemopreventive effects on colorectal carcinogenesis under the HFD condition. Furthermore, the concentration of Aloe-sterols was similar between 3% AVGP and H-AVGE, suggesting that Aloe-sterols were the main active ingredients in this experiment.

Successful Direct Iliac Transcatheter Aortic Valve Implantation to Overcome Significant Tortuosity of the Thoracic Aorta

Umihiko Kaneko,Ken Kobayashi,Daisuke Hachinohe,Satoshi Sumino,Azusa Furugen,Takeshi Kawamura,Hirosato Doi,Tsutomu Fujita 대한심장학회 2018 Korean Circulation Journal Vol.48 No.10