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C60(OH)n-ASSISTED DISPERSION OF SINGLE-WALLED CARBON NANOTUBES
YUTAKA MAEDA,TAKAAKI KATO,JUNKI HIGO,TADASHI HASEGAWA,TAKAHIRO KITANO,TAKAHIRO TSUCHIYA,TAKESHI AKASAKA,TOSHIYA OKAZAKI,JING LU,SHIGERU NAGASE 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2008 NANO Vol.3 No.6
We demonstrate that C60(OH)n-assists the dispersion of SWNTs in aqueous and nonaqueous solutions, which effectively exfoliates large-diameter SWNTs. The SWNT dispersions are characterized by absorption and photoluminescence spectra.
Takahiro MIYAJIMA,Takumi TOKISA,Shinya MAEDA,Hyoungseop KIM,Joo Kooi TAN,Seiji ISHIKAWA,Seiichi MURAKAMI,Takatoshi AOKI 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10
Recently, thorax MDCT images are used in visual screening for early detection of lung nodules. Radiologists can easily detect lung nodules on images, but it has enormous images and load of radiologist for visual screening. To reduce the load of radiologist and improve the detection accuracy, a CAD (Computer Aided Diagnosis) system is expected from medical fields. In the medical image processing fields, some related works are reported to develop the CAD system including temporal subtraction technique as helpful technical issues. In this paper, we propose a classification of lung nodules on temporal subtraction image based on image processing technique. At first, the candidate regions including nodules are detected by the multiple threshold technique in terms of the pixel value on the temporal subtraction images. Then, we remove vessel regions on nodules by the most suitable threshold technique and watershed method. Also we remove the false positives which are caused by mis-registration using selective enhancement filter, rule-base method and artificial neural networks. In this paper, we illustrate some experimental result which applied our algorithm to 31 chest MDCT cases including lung nodules.
Shogo Maeda,Shinsaku Kawabata,Itsuki Nagase,Ali Baratov,Masaki Ishiguro,Toi Nezu,Takahiro Igarashi,Kishi Sekiyama,Suguru Terai,Keito Shinohara,Melvin John F. Empizo,Nobuhiko Sarukura,Masaaki Kuzuhara 대한전자공학회 2024 Journal of semiconductor technology and science Vol.24 No.1
We have compared the electrical performance of a proposed normally-off GaN-based MIS-HEMTs employing ultrathin AlGaN barrier layer in the channel with those of conventional recessed-gate structure MIS-HEMTs. The proposed device exhibited much less density of interface states extracted from the measured capacitance-voltage characteristics, suggesting improved Al2O3/AlGaN interface. For corresponding three-terminal transistors, while the conventional reference device exhibited poor control of gate-to-source voltage on drain current with about 3 V hysteresis in the transfer curves, the proposed device showed well-behaved subthreshold characteristics with only 0.8 V hysteresis. Furthermore, the proposed device showed a much higher VTH of +5 V compared to +1 V of the conventional reference device.
Takashi Takahashi,Takahiro Maeda,Seungjun Lee,Dong-Hyun Lee,Sunjoo Kim 대한진단검사의학회 2020 Annals of Laboratory Medicine Vol.40 No.5
Background: The clindamycin-resistant erythromycin-susceptible (CRES) phenotype is rare in Streptococcus agalactiae (group B streptococci). We aimed to determine the molecular characteristics of CRES S. agalactiae using whole genome sequencing (WGS). Methods: Sixty-six S. agalactiae isolates obtained from blood (N=26), cerebrospinal fluid (N=10), urine (N=17), and vaginal discharge (N=13) between 2010 and 2017 in Korea were subjected to WGS. Based on the WGS data, we analyzed antimicrobial resistance (AMR) determinants, sequence types (STs), capsular polysaccharide (CPS) genotypes, and virulence gene profiles, and constructed a phylogenetic tree. We included the clindamycin-susceptible erythromycin-resistant (CSER) phenotype for comparison. Results: We identified seven CRES S. agalactiae isolates from urine (N=5) and vaginal discharge (N=2) collected between 2010 and 2011. All CRES isolates harbored AMR determinants of lnu(B), lsa(E), and aac(6’)-aph(2’’), revealed ST19 and CPS genotype III, and had a virulence gene profile of rib-lmb-cylE. Phylogenetic tree analysis revealed that all CRES isolates belonged to the same cluster, suggesting a clonal distribution. In contrast, seven CSER isolates showed a diverse distribution and clustered separately from the CRES isolates. Conclusions: CRES isolates collected between 2010 and 2011 showed a unique cluster with ST19 and CPS genotype III in Korea. This is the first report on WGS-based characteristics of S. agalactiae in Korea.
Takamasa Takahashi,Yuji Kaneoka,Atsuyuki Maeda,Yuichi Takayama,Hiroki Aoyama,Takahiro Hosoi,Kazuaki Seita 대한내시경로봇외과학회 2023 Journal of Minimally Invasive Surgery Vol.26 No.2
Purpose: In minimally invasive esophagectomy (MIE), it is important to reduce the rate of anastomotic leakage to ensure its safety. At our institute, the double-ligation method (DLM) has been introduced to insert and fix the anvil of the circular stapler for intracorporeal circular esophagojejunostomy in gastric surgery. We adopted this method for intrathoracic anastomosis (IA) in MIE. The aim of this study was to investigate the safety of IA with DLM in MIE. Methods: In this study, 48 patients diagnosed with primary middle or lower third segment thoracic esophageal carcinoma with clinical stage I, II, III or IV disease were retrospectively evaluated. Postoperative outcomes were assessed. Results: Among the 48 patients, 42 patients underwent laparo-thoracoscopic esophagectomy and IA using a circular stapler with the DLM. The average total operation time and thoracoscopic operation time were 433 and 229 minutes, respectively. The average pursestring suturing time was 4.7 minutes. The rates of anastomotic leakage and stenosis were 2.4% and 14.3%, respectively. The overall incidence of postoperative complications (Clavien- Dindo grade of ≥III) was 16.7%. The average postoperative stay was 16 days. Conclusion: The procedure of IA using a circular stapler with the DLM in MIE was safe and provided a low rate of anastomotic leakage.
TADASHI HASEGAWA,TAKESHI AKASAKA,YUTAKA MAEDA,MASAHIRO HASHIMOTO,MAKOTO KANDA,TAKAHIRO TSUCHIYA,TAKATSUGU WAKAHARA,YUHEI MIYAUCHI,SHIGEO MARUYAMA,JING LU,SHIGERU NAGASE 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2007 NANO Vol.2 No.4
Single-walled carbon nanotubes (SWNTs) synthesized by catalytic decomposition of an alcohol were purified by extraction. The purified SWNTs were characterized on the basis of visible-near infrared (vis-NIR) absorption, photoluminescence and Raman spectroscopic analyses, scanning electron microscopy (SEM) observation, and thermal analysis. Selective extraction of metallic nanotubes was also achieved by the extraction condition.
Yoshida Haruno,Kim Jung-Min,Maeda Takahiro,Goto Mieko,Tsuyuki Yuzo,Shibata Sachiko,Shizuno Kenichi,Okuzumi Katsuko,Kim Jae-Seok,Takahashi Takashi 대한진단검사의학회 2023 Annals of Laboratory Medicine Vol.43 No.3
Background: Comparative analysis of virulence factors (VFs) between Pasteurella canis and Pasteurella multocida are lacking, although both cause zoonotic infections. We determined the virulence-associated genome sequence characteristics of P. canis and assessed the toxin gene prevalence unique to P. canis among clinical isolates of P. canis and P. multocida. Methods: We selected 10 P. canis and 16 P. multocida whole-genome sequences (WGSs) from the National Center for Biotechnology database. The VFanalyzer tool was used to estimate P. canis-characteristic VFs. Amino acid sequences of VFs were compared with multiple-aligned sequences. The genome structure containing P. canis-characteristic and adjacent loci was compared to the corresponding P. multocida genome structure. After designing primer sequences and assessing their accuracy, we examined the gene prevalence of the P. canis-characteristic VFs using PCR among clinical isolates of P. multocida and P. canis. Results: Using VFanalyzer, we found virulence-associated cytolethal distending toxin (cdt)A–cdtB–cdtC loci common to all P. canis WGSs that were not found in P. multocida WGSs. Similarities in the multiple alignments of CdtA–CdtB–CdtC amino acid sequences were found among the 10 P. canis WGSs. Shared or similar loci around cdtA–cdtB–cdtC were identified between the P. canis and P. multocida genome structures. The PCR-based cdtA–cdtB–cdtC prevalence differed for P. canis and P. multocida clinical isolates. Conclusions: P. canis-specific cdtA–cdtB–cdtC prevalence was identified among clinical isolates. These three loci may be unique toxin genes and promising targets for the rapid identification of P. canis in clinical settings.