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- 저자 : Takaaki Matsumoto (검색결과 12 건)
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Multimodal Analysis of Prompt and Delayed Neutron Emission in Fission
Takaaki Ohsawa,Atsushi Matsumoto 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
The multimodal model of fission, in which the nucleus is considered tofollow a distinctive path on the deformation energy surface, finallyreaching a definite scission point configuration, has been proved to give agood description of the mass and kineticenergy distributions of fissionfragments. The Madland-Nix model of prompt fission neutron spectra (PFNS)considered the cooling of the fission fragments by neutron emission and theenergy dependence of the inverse reaction, providing a basic formalism forevaluation of the PFNS. Combination of the two models led to the multimodalMadland-Nix model. With further extension to consider the shell effects onthe level density and asymmetry in neutron multiplicity and nucleartemperature of the fragments, it was successfully applied to evaluation ofthe PFNS. On the other hand, the summation method of the delayed neutronyields (DNY) is the most fundamental approach to the estimation of thequantity. Combination of the method with the multimodal fission model led toa new approach to interpret the energy dependence of the DNY. Thisphysics-based approach has made it possible to understand the PFNS and DNYin a manner consistent with many other facets of fission physics. Someproblems about possible effects of scission neutrons, anisotropy of neutronemission in the center-of-mass system of the fragments, and neutron emissionduring acceleration are discussed.
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Tomohiro Matsumoto,Shiro Imagama,Hidenori Inoue,Takaaki Aoki,Naoki Ishiguro,Yoshimitsu Osawa 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.6
Study Design: Prospective comparative study. Purpose: To compare the incidence and severity of adverse reactions associated with myelography performed in outpatients vs. in inpatients and report the safety and usefulness of outpatient myelography in Japanese patients. Overview of Literature: Myelography is normally performed as an inpatient procedure in most hospitals in Japan. No studies have reported the usefulness and adverse effects of outpatient myelography in Japanese patients. Methods: We performed 221 myelography procedures. Eighty-five of the 221 patients underwent outpatient myelography using our new protocol. The incidence and severity of adverse reactions were compared with the other 136 patients, who underwent conventional inpatient myelography. We further compared the cost of outpatient and inpatient myelography. Results: The overall rate of adverse effects was 9.4% in outpatients, as compared with 7.4% in inpatients. Overall, 1.2% of outpatients and 0.74% inpatients experienced “severe” adverse effects (requiring hospitalization). There were no significant differences between the 2 groups in either the overall rate of adverse effects or the rate of “severe” adverse effects. Moreover, the average outpatient procedure cost was only one-third to one-half that of the inpatient procedure. Conclusions: This was the first study to address the safety and usefulness of outpatient myelography in Japanese patients. If selected according to proper inclusion criteria for outpatient procedure, no significant differences were observed in the adverse effects between inpatients and outpatients. The outpatient procedure is more economical and has the added benefit of being more convenient and time-efficient for the patient.
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Jeong-Beom Lee,Matsumoto Takaaki,Young-Ki Min,Hun-Mo Yang 한국실험동물학회 2008 Laboratory Animal Research Vol.24 No.4
Pikas inhabiting cold zones or high altitudes in the mountains are thought to be adapted to both the cold as well as to the high-altitude. However, the heat tolerance to heat exposure and insulative cold defenses in pikas has not been previously studied. Whether pikas have a circadian rhythm is controversial based on field observations. Comparisons of the ear to body surface area ratio of the rabbits, rats and pikas, has shown that the pikas have smaller ratios than the rabbits (P<0.001). Comparison of the body weights and blood glucose levels of the rabbits, rats and pikas, has shown that the pikas have lower levels than the rabbits (P<0.01). Comparison of the body temperatures of rabbits, rats and pikas, showed that the pikas had higher levels than the rabbits and rats (P<0.01). Comparison of the red blood cell count of the rabbits, rats and pikas, showed that the pikas had higher counts than the rabbits and rats (P<0.001). Therefore, autonomic characteristics including high body temperature, high metabolism and a poor heat loss ability such as poor panting and small ear pinnae were noted. In addition, it has been observed that behavioral characteristics including the fact that pikas live in burrows under the ground or in the shelter among rocks and hoard grasses for winter food to survive the winters. In conclusion, the pikas adapt to the cold not only ecologically and autonomically but also as a result of insulating cold defense mechanisms. Additional research is needed to better understand the absence of circadian body temperature rhythm in the pikas, which might also advance our understanding of circadian rhythm.
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Long-Term Tropical Residency Diminishes Central Sudomotor Sensitivities in Male Subjects
이정범,배준상,신영오,강종철,Takaaki Matsumoto,Aliopva Aziza Toktasynovna,Alipov Gabit Kaimovich,김완종,민영기,양훈모 대한약리학회 2007 The Korean Journal of Physiology & Pharmacology Vol.11 No.6
Tropical natives (TROP) are capable of tolerating tropical heat because of their long-term adaptation to tropical environments. When exposed to heat stress, these natives tend to respond with lower sweat output, which is generally thought to be the result of heat acclimatization. The main objective of this study was to clarify central mechanisms inherent to suppressed thermal sweating in tropical natives (Malaysians) by comparing their sweating responses to those of temperate native (TEMP) (Koreans). This experiment was conducted in a thermoneutral climatic chamber (24±0.5oC, 40±3% relative humidity). Heat loads were applied to each subject by the immersion of their lower legs in a hot water bath (43oC for 30 min). Sweat onset-time and sweat volume were compared between TROP and TEMP. The sweat onset-times on four selected points on the body ranged from 10.25 to 13.47 min in TEMP subjects, and from 16.24 to 17.83 min in TROP subjects (p<0.001). The local sweat volumes at the same sites ranged from 4.30 to 9.74 mg/cm2 in TEMP subjects, and from between 1.80 to 4.40 mg/cm2 in TROP subjects (p<0.001). These results demonstrated a significant difference between TROP and TEMP subjects with regard to the manner in which they regulate their body temperatures when exposed to heat loads, and verified that long-term thermal adaptation blunts sweating sensitivities.
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Yuma Onoi,Takafumi Hiranaka,Yuichi Hida,Takaaki Fujishiro,Koji Okamoto,Tomoyuki Matsumoto,Ryosuke Kuroda 대한정형외과학회 2022 Clinics in Orthopedic Surgery Vol.14 No.3
Background: To evaluate the clinical outcomes and second-look arthroscopic findings after intra-articular adipose-derived regenerative cell (ADRC) injection as treatment for knee osteoarthritis (OA). Methods: ADRCs were administered to 11 patients (19 knees; mean age, 61.7 years) with knee OA. Subcutaneous adipose tissue was harvested by liposuction from both thighs, and arthroscopic lavage was performed, followed by ADRC injection (mean dose, 1.40 × 107 cells) into the synovial fluid. Outcome measures included the Knee Injury and Osteoarthritis Outcome Score, Lysholm score, and visual analog scale score. Arthroscopic examinations were performed to assess the International Cartilage Repair Society cartilage injury grade preoperatively and overall repair postoperatively. Noninvasive assessments were performed at baseline and at 1-, 3-, and 6-month follow-ups; arthroscopic assessments were performed at baseline and at 6 months. Results: All outcome measures significantly improved after treatment. This improvement was evident 1 month after treatment and was sustained until the 6-month follow-up. Data from second-look arthroscopy showed better repair in low-grade cartilage lesions than in lesions with a greater degree of damage. No patients demonstrated worsening of Kellgren-Lawrence grade, and none underwent total knee arthroplasty during this period. Conclusions: Clinical outcomes were improved in patients with knee OA after ADRC administration. Cartilage regeneration was more effective in smaller damaged lesions than in bigger lesions.
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Long-Term Tropical Residency Diminishes Central Sudomotor Sensitivities in Male Subjects
Jeong-Beom Lee,Jun-Sang Bae,Young-Oh Shin,Jong-Chul Kang,Takaaki Matsumoto,Aliopva Aziza Toktasynovna,Alipov Gabit Kaimovich,Wan-Jong Kim,Young-Ki Min,Hun-Mo Yang 대한생리학회-대한약리학회 2007 The Korean Journal of Physiology & Pharmacology Vol.11 No.6
Tropical natives (TROP) are capable of tolerating tropical heat because of their long-term adaptation to tropical environments. When exposed to heat stress, these natives tend to respond with lower sweat output, which is generally thought to be the result of heat acclimatization. The main objective of this study was to clarify central mechanisms inherent to suppressed thermal sweating in tropical natives (Malaysians) by comparing their sweating responses to those of temperate native (TEMP) (Koreans). This experiment was conducted in a thermoneutral climatic chamber (24±0.5<SUP>o</SUP>C, 40±3% relative humidity). Heat loads were applied to each subject by the immersion of their lower legs in a hot water bath (43<SUP>o</SUP>C for 30 min). Sweat onset-time and sweat volume were compared between TROP and TEMP. The sweat onset-times on four selected points on the body ranged from 10.25 to 13.47 min in TEMP subjects, and from 16.24 to 17.83 min in TROP subjects (p<0.001). The local sweat volumes at the same sites ranged from 4.30 to 9.74 mg/cm<SUP>2</SUP> in TEMP subjects, and from between 1.80 to 4.40 mg/cm<SUP>2</SUP> in TROP subjects (p<0.001). These results demonstrated a significant difference between TROP and TEMP subjects with regard to the manner in which they regulate their body temperatures when exposed to heat loads, and verified that long-term thermal adaptation blunts sweating sensitivities.
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Long-Term Tropical Residency Diminishes Central Sudomotor Sensitivities in Male Subjects
Lee, Jeong-Beom,Bae, Jun-Sang,Shin, Young-Oh,Kang, Jong-Chul,Matsumoto, Takaaki,Toktasynovna, Aliopva Aziza,Kaimovich, Alipov Gabit,Kim, Wan-Jong,Min, Young-Ki,Yang, Hun-Mo The Korean Society of Pharmacology 2007 The Korean Journal of Physiology & Pharmacology Vol.11 No.6
Tropical natives (TROP) are capable of tolerating tropical heat because of their long-term adaptation to tropical environments. When exposed to heat stress, these natives tend to respond with lower sweat output, which is generally thought to be the result of heat acclimatization. The main objective of this study was to clarify central mechanisms inherent to suppressed thermal sweating in tropical natives (Malaysians) by comparing their sweating responses to those of temperate native (TEMP) (Koreans). This experiment was conducted in a thermoneutral climatic chamber ($24{\pm}0.5^{\circ}C,\;40{\pm}3%$ relative humidity). Heat loads were applied to each subject by the immersion of their lower legs in a hot water bath ($43^{\circ}C$ for 30 min). Sweat onset-time and sweat volume were compared between TROP and TEMP. The sweat onset-times on four selected points on the body ranged from 10.25 to 13.47 min in TEMP subjects, and from 16.24 to 17.83 min in TROP subjects (p<0.001). The local sweat volumes at the same sites ranged from 4.30 to $9.74 mg/cm^2$ in TEMP subjects, and from between 1.80 to $4.40mg/cm^2$ in TROP subjects (p<0.001). These results demonstrated a significant difference between TROP and TEMP subjects with regard to the manner in which they regulate their body temperatures when exposed to heat loads, and verified that long-term thermal adaptation blunts sweating sensitivities.
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Economical Sweating Function in Africans: Quantitative Sudomotor Axon Reflex Test
이정범,배준상,최정환,함주현,민영기,양훈모,Shimizu Kazuhiro,Takaaki Matsumoto 대한약리학회 2004 The Korean Journal of Physiology & Pharmacology Vol.8 No.1
People in tropics have the ability to tolerate heat by residential permanence in the tropics. Previously, we have shown that African and Thai subjects who lived for whole their lives in only their respective countries sweat less under hot conditions than South Koreans who also lived whole their lives in Korea. The difference in sweating responses was attributed to the dissimilar central and peripheral sweating mechanisms operating in people from both groups. In the present study, acetylcholine (ACh), the primary transmitter for the sudomotor functions, was iontophoretically administered to South Koreans and Africans to determine the characteristic sudorific responses of their acclimatized biologic make-up to their respective environments. Using quantitative sudomotor axon reflex test (QSART), direct (DIR) and axon reflex (AXR) responses were evaluated. The findings revealed that the sweat onset-time among South Koreans was 0.91 min earlier than among Africans (P<0.01). The axon reflex sweat volume of nicotine receptor activity AXR(1) and sweat volume of muscarinic receptor activity DIR(2) among South Koreans were 79% and 53% greater (P<0.01), respectively. These results indicate that the reduced thermal sweating among Africans is at least in part attributed to the diminished sensitivity of sweat glands to ACh.
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