http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Taher Taheri (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
( Payman Salamati ),( Reza Rostami ),( Soheil Saadat ),( Taher Taheri ),( Maryam Tajabadi ),( Ghazale Ranjbari ),( Zohrehsadat Naji ),( Saba Jafarpour ),( Vafa Rahimi Movaghar ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Patients with spinal cord injury (SCI) have a lower health related quality of life (HRQOL) in comparison with both healthy controls and the normal population. The aim of this study was to compare HRQOL between two groups of veteran and non-veteran SCI patients. Methods: Male paraplegic non-veterans who had sustained complete SCI before the year 1988 and were residents of Tehran province, Iran, and a similar group of SCI veterans were enrolled in this study. The participants were interviewed based on the Iranian version of SF-36 questionnaire by two psychologists. Eight sub-scales and two physical and mental component summaries of the instrument were assessed. We used chi-square, odds ratio, Mann-Whitney U, independent t-test, and linear regression for analysis. Results: Overall, 25 veterans and 22 non-veterans were enrolled in the study. The mean age, time since injury, and presence of comorbid illnesses were not signifi cantly different between veterans and non-veterans. A greater number of veterans were married (P=0. 003) and employed (P=0. 047). On average, veterans had more years of formal education than non-veterans (P=0. 001). The mean (SD) bodily pain sub-scale was 72. 73(31. 253) for non-veterans and 49. 7(28. 287) for veterans (P=0. 011). Absence of comorbid illnesses was associated with a better physical component summary (P<0. 001). Employment was associated with a better mental component summary (P=0. 022). Conclusions: We did not fi nd any difference in HRQOL between the two groups except for the bodily pain sub-scale. Further studies with larger sample sizes are recommended.
-
Samane Adib,Taki Tiraihi,Merzieh Darvishi,Taher Taheri,Hadi Kazemi 한국조직공학과 재생의학회 2015 조직공학과 재생의학 Vol.12 No.1
Human Bone marrow stromal cells (hBMSCs) can differentiate under appropriate experimental conditionsinto neuronal and glial-like cells. This study shows a protocol for producing human neural stem cells (hNSCs)from hBMSCs and the subsequent differentiation of hNSCs into cholinergic neurons (CNs), where sequential mediareplaced the culturing media. hBMSCs have been used in generating cell aggregates (CAs) using bFGF, EGF andB27. The hNSCs were isolated from CAs, and the CNs differentiated from the hNSCs using sequential media, wherebFGF, EGF and B27 were gradually replaced with NGF. The hNSC stemness was checked by RT-PCR of SOX2,Oct-4 and Nanog genes. Fibronectin, CD90, CD106, CD31, nestin, neurofilament 68 (NF-68), NF-200 and ChATimmunostaining evaluated the differentiation of the hBMSCs, the hNSCs and the CNs. FM1-43 was used in studyingthe function of the CNs. The hBMSCs were immunoreactive to fibronectin, CD90 and CD106; they werechecked for lipogenic and osteogenic differentiation. The cells of the CAs were immunoreactive to nestin. ThehNSCs were immunoreactive to nestin and NF-68, also, they expressed SOX2, Oct-4 and nanong. Nestin expressiondeclined sharply following NSC differentiation into CNs, while the expression of NF-200, synapsin I, synaptophysin,MAP-2 and ChAT increased. They were stained with FM1-43, where the synaptic vesicles were releasedfollowing stimulation. The present study demonstrates the conversion of hBMSCs into CASs under appropriate conditions. CAs generated hNSCs, which were induced in order to differentiate into CNs using sequential media, wherethe yield was 83%.
-
Hamid Aboutaleb Kadkhodaeian,Taki Tiraihi,Hamid Ahmadieh,Hossein Ziaei,Narsis Daftarian,Taher Taheri 한국조직공학과 재생의학회 2019 조직공학과 재생의학 Vol.16 No.3
BACKGROUND: Retinal degeneration causes blindness, and cell replacement is a potential therapy. The purpose of this study is to formation of pigmented neurospheres in a simple medium, low-cost, high-performance manner over a short period of time while expressing markers of RPE cells and the activation of specific genes of the pigment cells. Also, these neurospheres have the ability to produce a monolayer of retinal pigment epithelium-like cells (RPELC) with the ability of photoreceptor outer segment phagocytosis. METHODS: BMSC were isolated from pigmented hooded male rats and were immunoreactive to BMSC markers, then converted into neurospheres, differentiated into pigmented spheres (PS), and characterized using Retinal pigment epithelium-specific 65 kDa protein (RPE65), Retinaldehyde-binding protein 1 (CRALBP) and orthodenticle homeobox 2 (OTX2) markers by immunocytochemistry, RT-PCR and RT-qPCR. The PS were harvested into RPELC. The functionality of RPELC was evaluated by phagocytosis of fluorescein-labeled photoreceptor outer segment. RESULTS: The BMSC immunophenotype was confirmed by immunostained for fibronectin, CD90, CD166 and CD44. These cells differentiated into osteogenic and lipogenic cells. The generated neurospheres were immunoreactive to nestin and stemness genes. The PS after 7–14 days were positive for RPE65 (92.76–100%), CRALBP (95.21–100%) and OTX2 (94.88–100%), and after 30 days RT-PCR, qPCR revealed increasing in gene expression. The PS formed a single layer of RPELC after cultivation and phagocyte photoreceptor outer segments. CONCLUSION: Bone marrow stromal stem cells can differentiate into functional retinal pigmented epithelium cells in a simple, low-cost, high-performancemanner over a short period of time. These cells due to expressing theRPELCgenes andmarkers can be used in cell replacement therapy for degenerative diseases including age-relatedmacular degeneration as well as retinitis pigmentosa.
-
Evaluation of Pain and Its Effect on Quality of Life and Functioning in Men with Spinal Cord Injury
( Marzieh Hassanijirdehi ),( Mohammad Khak ),( Sohrab Afsharimirak ),( Kourosh Holakouienaieni ),( Soheil Saadat ),( Taher Taheri ),( Vafa Rahimimovaghar ) 대한통증학회 2015 The Korean Journal of Pain Vol.28 No.2
Background: Pain is one of the most important consequences of spinal cord injury (SCI). It may affect several aspects of life, especially the quality of life (QoL). Hence, this study was conducted to establish an understanding of pain and its correlates and effects on patients with SCI in our community. Methods: In a cross-sectional study, 58 male veterans suffering from SCI were admitted to our center for a regular follow-up. Demographic and SCI-related descriptive information were gathered using a self-reported questionnaire. To evaluate the patients’ pain quality and the effect of pain on daily life, a questionnaire in 3 parts of lumbar, cervical and shoulder pain was administered. EuroQoL questionnaire and General Health Questionnaire (GHQ) 12 were also used to assess the patients’ QoL. Results: The mean age of the participants was 45.91 ± 6.69 with mean injury time of 25.54 ± 5.91. forty-four patients (75.9%) reported pain, including lumbar pain (63%), cervical pain (39%) and shoulder pain (51%). The presence of pain was associated with lower QoL. Patients with lumbar pain reported a significant amount of pain affecting their daily life and this effect was higher in patients with lower GHQ score or anxiety/depressive disorder. Conclusions: Musculoskeletal pain, is a common complaint in veterans with SCI and is inversely associated with functioning and general health status. Lumbar and shoulder pain affects patient’s daily living more than cervical pain. (Korean J Pain 2015; 28: 129-136)
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
