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Son, Dae-Yong,Lee, Chang-Ryul,Shin, Hee-Won,Jang, In-Hyuk,Jung, Hyun Suk,Ahn, Tae Kyu,Park, Nam-Gyu The Royal Society of Chemistry 2015 Physical chemistry chemical physics Vol.17 No.23
<P>To understand the role of the dye/oxide interface, a model system using a nanocrystalline SnO<SUB>2</SUB> and 3-hexyl thiophene based MK-2 dye is proposed. A thin interfacial TiO<SUB>2</SUB> blocking layer (IBL) is introduced in between SnO<SUB>2</SUB> and MK-2 and its effects on photocurrent–voltage, electron transport-recombination, and density of states (DOS) are systematically investigated. Compared to the bare SnO<SUB>2</SUB> film, the insertion of IBL leads to a 14-fold improvement in the power conversion efficiency (PCE) despite little change in the dye adsorption amount, which is due to the 7-fold and 2-fold increase in the photocurrent density and voltage, respectively. The charge collection efficiency is substantially improved from 38% to 96% mainly due to the increase in the electron lifetime. The IBL is also found to enhance the dye regeneration efficiency as confirmed by the 15-fold faster dye bleaching recovery dynamics. The recombination resistance increases and the DOS decreases after surface modification of SnO<SUB>2</SUB>, which is responsible for the doubly increased voltage. This study suggests that the interfacial layer between the oxide and the dye plays a crucial role in retarding recombination, improving charge collection efficiency, increasing diffusion length, accelerating dye regeneration and narrowing the density of states.</P> <P>Graphic Abstract</P><P>The interfacial blocking layer between dye and oxide was found to play crucial roles in retarding recombination, increasing diffusion, accelerating dye regeneration and narrowing the density of states. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c5cp01816a'> </P>
Development of a Driving Simulator for Telematics Human-Machine Interface Studies
Tae-Yun Koo,Bae-Young Kim,Jung-Hun Park,Young-Tak Son,Myung-won Suh 한국자동차공학회 2008 한국자동차공학회 Symposium Vol.2008 No.9
Driving simulators are useful tools not only to test the components of future cars but also to evaluate the telematics service and HMI (Human-Machine Interface). However driving simulators available at present cannot be implemented to test and evaluate the telematics service system since the GPS (Global Positioning System), which contains basic functional support for the telematics module, does not work in the VR (virtual reality) environment. In this paper, a GPS simulator is developed which is able to emulate GPS satellite signals, consisting of the NMEA-0183 protocol and RS232C communication standards, and thereby presenting a method of implementing a telematics service for a driving simulator. It is expected that the driving simulator, together with the GPS simulator, can be used to study the HMI for evaluation of commercial telematics systems in order to realize the HiLESs (Human-in-the-Loop Evaluation Systems).
<i>Rhodanobacter koreensis</i> sp. nov., a bacterium isolated from tomato rhizosphere
Won, KyungHwa,Singh, Hina,Ngo, Hien T. T.,Son, HeungMin,Kook, MooChang,Kim, Ki–,Young,Yi, Tae–,Hoo International Union of Microbiological Societies 2015 International journal of systematic and evolutiona Vol.65 No.4
<P>A Gram-stain-negative, aerobic, rod-shaped and motile bacterium, designated THG-DD7<SUP>T</SUP>, was isolated from tomato plant rhizosphere soil. Strain THG-DD7<SUP>T</SUP> grew optimally at 25–30 °C, at pH 7.0–7.5 and in the presence of 0.5 % (w/v) NaCl. According to the results of 16S rRNA gene sequence comparisons, strain THG-DD7<SUP>T</SUP> was most closely related to <I>Rhodanobacter umsongensis</I> GR24-2<SUP>T</SUP> (98.2 %), <I>Rhodanobacter panaciterrae</I> LnR5-47<SUP>T</SUP> (98.0 %), <I>Rhodanobacter soli</I> DCY45<SUP>T</SUP> (97.9 %), <I>Rhodanobacter terrae</I> GP18-1<SUP>T</SUP> (97.9 %) and <I>Dyella ginsengisoli</I> Gsoil 3046<SUP>T</SUP> (97.7 %). The DNA G+C content was 65.2 mol%. In DNA–DNA hybridization, the DNA relatedness levels between strain THG-DD7<SUP>T</SUP> and its closest phylogenetically neighbours were below 40.0 %. The predominant isoprenoid quinone was ubiquinone Q-8. The major polar lipids were diphosphatidylglycerol, phosphtidylethanolamine, phosphatidyl-<I>N</I>-methylethanolamine and phosphatidylglycerol. The major fatty acids were iso-C<SUB>15 : 0</SUB>, iso-C<SUB>16 : 0</SUB>, iso-C<SUB>17 : 0</SUB>, anteiso-C<SUB>15 : 0</SUB> and iso-C<SUB>17 : 1</SUB>ω9<I>c</I> and/or C<SUB>16 : 0</SUB> 10-methyl (summed feature 9). These data supported the affiliation of strain THG-DD7<SUP>T</SUP> to the genus <I>Rhodanobacter</I> . The results of physiological and biochemical tests enabled strain THG-DD7<SUP>T</SUP> to be differentiated genotypically and phenotypically from the species of the genus <I>Rhodanobacter</I> with validly published names. Therefore, the novel isolate represents a novel species, for which the name <I>Rhodanobacter koreensis</I> sp. nov. is proposed. The type strain is THG-DD7<SUP>T</SUP> ( = KACC 17650<SUP>T</SUP> = JCM 19614<SUP>T</SUP>).</P>
( Tae Su Jang ),( Hai Yan Zhang ),( Geum Jin Kim ),( Dong Woo Kim ),( Byung Sun Min ),( Won Ku Kang ),( Kun Ho Son ),( Min Kyun Na ),( Seung Ho Lee ) 영남대학교 약품개발연구소 2012 영남대학교 약품개발연구소 연구업적집 Vol.22 No.0
Fatty acid synthase (FAS) is considered as a novel drug target for the development of anticancer and anti-obesity agents. Bioassay-guided fractionation of a n-hexane-soluble extract prepared from the roots of Salvia miltiorrhiza Bunge (Labiatae), using an in vitro enzyme assay, led to the isolation of five abietane diterpenoids: 15,16-dihydrotanshinone I (1), cryptotanshinone (2), tanshinone I (3), tanshinone IIA (4), and dansenspiroketallactone (5). Compounds 1-5 were tested for their in vitro FAS inhibitoryactivity and, except for compound 5 (IC(50) > 100 μM), compounds 1-4 inhibited the enzyme activity with IC(50) values ranging from 12.0 to 30.3 μM. Our findings may be partially related to the anticancer activity of abietane diterpenoids from the plant, suggesting a further study on the anticancer potential of tanshinone derivatives.
Son, Dong Ick,Shim, Jae Ho,Park, Dong Hee,Jung, Jae Hun,Lee, Jung Min,Park, Won Il,Kim, Tae Whan,Choi, Won Kook IOP Pub 2011 Nanotechnology Vol.22 No.29
<P>We present data, which were obtained before bending and after bending, for the electrical bistabilities, memory stabilities, and memory mechanisms of three-layer structured flexible bistable organic memory (BOM) devices, which were fabricated utilizing the ultrathin graphite sheets (UGS) sandwiched between insulating poly(methylmethacrylate) (PMMA) polymer layers. The UGS were formed by transferring UGS (about 30 layers) and using a simple spin-coating technique. Transmission electron microscopy (TEM) measurements were performed to investigate the microstructural properties of the PMMA/UGS/PMMA films. Current–voltage (<I>I</I>–<I>V</I>) measurements were carried out to investigate the electrical properties of the BOM devices containing the UGS embedded in the PMMA polymer. Current–time (<I>I</I>–<I>t</I>) and current–cycle measurements under flat and bent conditions were performed to investigate the memory stabilities of the BOM devices. The memory characteristics of the BOM maintained similar device efficiencies after bending and were stable during repeated bendings of the BOM devices. The mechanisms for these characteristics of the fabricated BOM are described on the basis of the <I>I</I>–<I>V</I> results. </P>
Son, Tae-Gen,Kim, So-Jung,Kim, Keun-Ho,Kim, Min-Sun,Chung, Hae-Young,Lee, Jae-Won 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.7
Senescence marker protein 30 (SMP30) is identified as an important aging marker molecule and known to play multifunctional roles as an intracellular calcium regulatory protein in the signaling process. To elucidate the functional significance of SMP30, we established the stably transfected P19 cell line with SMP30 expression vector. Overexpression of SMP30 slightly suppressed the proliferation of P19 cells. However, SMP30 overexpression was cytoprotective against calcium-mediated stress such as calcium ionophore (A23187), and thapsigargin. We found that SMP30 overexpression reduced the elevated intracellular calcium levels induced by A23187, but not by thapsigargin. In addition, SMP30 transfected P19 cells were more protective to tert-butylhydroperoxide induced cytotoxicity, indicating the antioxidative properties of SMP30. Taken together, our results suggest that external calcium regulation and antioxidant properties are involved in the cytoprotective mechanism of SMP30.
Genotypic characterization of fluoroquinolone-resistant Escherichia coli isolates from edible offal
Son, Se Hyun,Seo, Kwang Won,Kim, Yeong Bin,Noh, Eun Bi,Lee, Keun-Woo,Oh, Tae-Ho,Kim, Seung-Joon,Song, Jae-Chan,Kim, Tae-Wan,Lee, Young Ju The Korean Society of Veterinary Science 2020 大韓獸醫學會誌 Vol.60 No.3
Edible offal is easily contaminated by Escherichia coli (E. coli) and fluoroquinolone (FQ)-resistant E. coli is considered a serious public health problem, thus, this study investigated the genetic characteristics of FQ-resistant E. coli from edible offal. A total of 22 FQ-resistant E. coli isolates were tested. A double mutation in each gyrA and parC led the highest MIC. Four (18.2%) isolates carried plasmid-mediated quinolone resistance genes. The fimH, eaeA, escV, astA, and iucC genes were confirmed. Seventeen isolates (77.3%) were positive for plasmid replicons. The isolates showed high genetic heterogeneity based on pulsed-field gel electrophoresis patterns.