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A Case-based Design Framework for Screen Transition Diagram of Web Application
Junya Shimada,Taiki Enomoto,Susumu Takeuchi,Masanori Akiyoshi,Norihisa Komoda 한국멀티미디어학회 2009 한국멀티미디어학회 국제학술대회 Vol.2009 No.-
Web applications are widely used on the Internet and Intranets. They are easy to be provided because a provider does not have to deploy them to each client. Accordingly, screen transition diagram (STD) is used to analyze the requirements of Web applications quickly. STD is useful to grasp the outline of the whole application, but analysts in most cases draw the diagrams from the scratch, even if they contain similar functionalities. This paper addresses a case-based design framework for supporting to draw STD of Web applications. In this framework, the analysts would combine different parts of STD over multiple Web applications, by dividing STDs into Web Page Transition Groups (WPTGs) based on the exchanged data among the screens. Moreover, a search support method to find appropriate WPTGs is considered in the framework.
WonKyung Kang,Susumu Katsuma,Noriko Matsuda-Imai,Masaaki Kurihara,Toyoshi Yoshiga,Toru Shimada,Shogo Matsumoto 한국미생물학회 2012 The journal of microbiology Vol.50 No.3
The orf8 gene (Bm8) in Bombyx mori nucleopolyhedrovirus (BmNPV) is one of 17 genes unique to group I NPVs and is expressed as an early gene. We have reported that Bm8 may play an important role during viral infection and that Bm8 protein co-localized with IE1 to specific nuclear foci throughout infection. It was also demonstrated that both IE1 and BmNPV hr facilitate this localization of Bm8. To investigate further, host proteins interacting with Bm8 were screened using a yeast two-hybrid system. We identified 6 host clones as Bm8-interacting partners from three cDNA libraries derived from BmN cells or B. mori larvae. Further assays showed that the N-terminal region of Bm8 is important for the interaction with most host clones and that two of the clones can associate with IE1. Cloning and sequencing of full-length cDNAs revealed that most of the clones potentially encode either membrane-bound proteins or secreted proteins. Quantitative RT-PCR analysis revealed that some of these host genes were slightly induced during the early stage of infection in BmN cells, and that the expression of all genes was markedly reduced during the late stage of infection. Generation of mutant BmNPVs over-expressing these host genes also identified a gene that potentially functions as a negative factor during BmNPV infection. These features of Bm8-interacting host proteins strongly support that Bm8 is a multifunctional protein involved in multiple signaling pathways in host cells.