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- 저자 : Sunhui Choi (검색결과 4 건)
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Jeongsuk Son,Sunhui Choi,Jin Won Huh,Chae-Man Lim,Younsuck Koh,Kang Mo Kim,Ju Hyun Shim,Young-Suk Lim,Sang-Bum Hong 대한내과학회 2020 The Korean Journal of Internal Medicine Vol.35 No.4
Background/Aims: The quick Sepsis-related Organ Failure Assessment (qSOFA) is a newly developed risk stratification tool, which has been presented along with a new sepsis definition, to classify infected patients outside of the intensive care unit (ICU). We evaluated the clinical usefulness of qSOFA for predicting adverse outcomes in sepsis patients with liver cirrhosis. Methods: We performed a retrospective cohort study to assess the utility of qSOFA in sepsis patients with liver cirrhosis for whom medical emergency teams (METs) were activated in general wards at an academic tertiary care hospital between March 2008 and December 2015. qSOFA, Systemic inflammatory response syndrome (SIRS), modified early warning score (MEWS), and sequential (sepsis- related) organ failure assessment (SOFA) scores were calculated according to data at MET activation. Results: Of 188 patients, 69 (36.7%) had a qSOFA score of 0 or 1 point and 119 (63.3%) had ≥ 2 points. The areas under the receiver operating characteristic curve (AUROC) for ICU transfer on the SOFA (AUROC, 0.691; 95% confidence interval [CI], 0.615 to 0.767) or MEWS (AUROC, 0.663; 95% CI, 0.586 to 0.739) were significantly higher compared to those for qSOFA (AUROC, 0.589; 95% CI, 0.507 to 0.671) or SIRS (AUROC, 0.533; 95% CI, 0.451 to 0.616). Conclusions: Our findings suggest that qSOFA score may have limited utility in predicting adverse outcomes in sepsis patients with liver cirrhosis at MET activation. Either MEWS or another screening tool is needed for detecting early sepsis in these patients.
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Hwang, Hee-Jin,Han, Sunhui,Jeon, Sangok,Seo, Joeun,Oh, Dongho,Cho, Seong-Wan,Choi, Young Wook,Lee, Sangkil Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.8
For the present study, rhEGF was encapsulated into solid lipid nanoparticles (SLNs). The SLNs were prepared by the $W_1/O/W_2$ double emulsification method combined with the high pressure homogenization method and the physical properties such as particle size, zeta-potential and encapsulation efficiency were measured. The overall particle morphology of SLNs was investigated using a transmission electron microscopy (TEM). The percutaneous skin permeation and accumulation property of rhEGF was evaluated using Franz diffusion cell system along with confocal laser scanning microscopy (CLSM). The mean particle size of rhEGF-loaded SLNs was $104.00{\pm}3.99nm$ and the zeta-potential value was in the range of -$36.99{\pm}0.54mV$, providing a good colloidal stability. The TEM image revealed a spherical shape of SLNs about 100 nm and the encapsulation efficiency was $18.47{\pm}0.22%$. The skin accumulation of rhEGF was enhanced by SLNs. CLSM image analysis provided that the rhEGF rat skin accumulation is facilitated by an entry of SLNs through the pores of skin.
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천종숙,서동애,허지혜,최선희,양유영 연세대학교 생활과학연구소 1998 生活科學論集 Vol.12 No.-
This study was initiated to investigate the design and dress making techniques used for the reformed Korean traditional apparel. The researchers collected the data from 1997 fall and winter collections from five well known manufacturers. The results of the study were as followings: 1. The most apparent features of the reformed Jogori design was elimination of the fastening and adaptation of various neckline shapes devised during the Yi dynasty. Most men's Jogori had pockets at the waist. 2. The traditional Jogori construction designs remained were the center back seam, neckline shapes, front bodice extension, and neckline binding. 3. The traditional pattern cutting method for pants was still in use. However the waist and ankle closures were simplified. And the patch pockets were attached on the both sides of pants. 4. The skirt design was changed most. The waist length wrap skirt was closed at the front. The high-waist sleeveless one-piece dress was also included in skirt design. 5. The fabric used for the most of apparels collected for this study was 100% cotton.
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Predictor for deteriorating ward patient with repetitive Medical Emergency Team activation
( Jin Won Huh ),( Ju-ry Lee ),( Youn-kyoung Jung ),( Jin-mi Lee ),( Yujung Shin ),( Sunhui Choi ),( Jeongsuk Son ),( Eun-joo Choi ),( Da Hye Kim ),( Younsuck Koh ),( Chae-man Lim ),( Sang-bum Hong ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-
Purpose: Recurrent clinical deterioration and repetitive activation of Medical Emergency Team (MET) may be associated with poor outcome. The purpose of this study is to analyze the clinical characteristics of patients with repetitive MET activation and to predict the repetitive MET activation at first MET activation. Methods: We retrospectively reviewed the data of deteriorating patients who were contacted to the MET of Asan Medical Center from Jan 2012 to Nov 2016. The repetitive MET activation means the case of activation within 72 hours after the first MET activation. Results: A total of 7,470 patients were included during the study period. Of these patients, 892 (11.9%) experienced repetitive MET activation. ICU admission rate (49.0% vs. 27.8%, p<0.001) and in-hospital mortality rate (51.7% vs. 36.6%, p<0.001) were higher in the repetitive MET activation group than in the group who were once MET activation. The repetitive MET activation were independently associated with hematologic malignancies (OR: 1.45, 95% CI: 1.13-1.90), activation by respiratory distress(OR: 1.51, 95% CI: 1.20-1.89), airway suctioning (OR: 1.57, 95% CI: 1.24-1.98), apply of Bipap (OR: 1.97, 95% CI: 1.20-3.22), high SOFA (OR: 1.11, 95% CI: 1.07-1.15), and high SpO2/FiO2 score (OR: 1.14, 95% CI: 1.05-1.24) at first MET activation. Conclusion: These risk factors may be useful to identify patients at risk of repetitive MET activation at first MET activation, and then we could classify the high risk group and apply the aggressive intervention for better outcome.
KCI
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