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Sung Soo Kim,Hyun Kuk Kim,Hyung Wook Park,Myung Ho Jeong,임경섭,Hae Jin Kee,Yu Hee Ryu,Han Byul Kim,Joo-Young Na,Young-Jae Ki,Keun-Ho Park,Dong-Hyun Choi,Ki Hong Lee,Nam Sik Yoon,Jeong Gwan Cho 대한심장학회 2020 Korean Circulation Journal Vol.50 No.1
Background and Objectives: Antiarrhythmic effect of renal denervation (RDN) after acute myocardial infarction (AMI) remains unclear. The goal of this study was to evaluate the effect of RDN on ventricular arrhythmia (VA) after AMI in a porcine model. Methods: Twenty pigs were randomly divided into 2 groups based on RDN (RDN, n=10; Sham, n=10). After implanting a loop recorder, AMI was induced by occlusion of the middle left anterior descending coronary artery. Catheter-based RDN was performed for each renal artery immediately after creating AMI. Sham procedure used the same method, but a radiofrequency current was not delivered. Electrocardiography was monitored for 1 hour to observe VA. One week later, the animals were euthanized and the loop recorder data were analyzed. Results: Ventricular fibrillation event rate and the interval from AMI creation to first VA in acute phase were not different between the 2 groups. However, the incidence of premature ventricular complex (PVC) was lower in the RDN than in the Sham. Additionally, RDN inhibited prolongation of the corrected QT (QTc) interval after AMI. The frequency of non-sustained or sustained ventricular tachycardia, arrhythmic death was lower in the RDN group in the early period. Conclusions: RDN reduced the incidence of PVC, inhibited prolongation of the QTc interval, and reduced VA in the early period following an AMI. These results suggest that RDN might be a therapeutic option in patients with electrical instability after AMI.
Lower limb ischemia after bee sting
Ryu, Hee Yun,Yoo, Min Seok,Park, Ji Young,Choi, Jae Woong,Ryu, Sung Kee,Kim, Seunghwan,Lee, Se Jin,Kim, Young Bin Yeungnam University College of Medicine 2016 Yeungnam University Journal of Medicine Vol.33 No.2
Bee sting causes mild symptoms such as urticaria and localized pain, and severe symptoms including anaphylaxis, cardiovascular collapse, and death. We reported on a patient with arterial thrombotic occlusion and severe ischemia in the lower limb after multiple bee stings. The patient was stung 5 times and complained of pallor, pain, and coldness in the left toe, and did not have dorsalis pedis pulsation. Computed tomography angiography showed multiple thrombotic occlusion of the anterior and posterial tibial artery below the knee. Local thrombolytic therapy using urokinase was administered and the occluded arteries were successfully recanalized.
Microsatellite Analysis of the Silkworm Strains (Bombyx mori) Originated from China
( Kee Young Ki ),( Pil Don Kang ),( Kang Sun Ryu ),( Ki Hwan Kim ),( Gyoo Byung Sung ),( Sang Deok Ji ),( Mi Ja Kim ),( Iksoo Kim ) 한국잠사학회 2012 International Journal of Industrial Entomology Vol.25 No.1
A total of 85 Chinese-origin silkworm strains preserved in Korea were genotyped for eight polymorphic microsatellite loci. We obtained per-locus number of alleles, ranging from 5 to 14 with an average value of 9.5, perlocus observed heterozygosity, ranging from 0.07 to 0.99, and per-locus polymorphic information content PIC), ranging from 0.34 to 0.82, indicating that some loci are highly variable. Phylogenetic analysis with the eight concatenated microsatellite loci showed no clustering on the basis of known strain characteristics. A total of 22 strain-specific apomorphic alleles, which discriminate 19 among 85 silkworm strains were obtained from eight loci. These strain-specific alleles, thus, can casually be utilized for the discrimination of applicable strains without any further typing of other loci. Furthermore, a substantial number of homozygote strains, represented by 27 among 76 alleles in eight loci were found. These results collectively suggest that the silkworm microsatellite DNA is actually and potentially important molecular markers for the eventual discrimination of silkworm strains that are preserved as hundreds in Korea.
S-264 The impact of anemia on two-year clinical outcomes in patients with Acute MI undergoing PCI
( Sang Jin Jeon ),( Ji Young Park ),( Sung Kee Ryu ),( Jae Woong Choi ),( Seung Woon Rha ),( Byoung Geol Choi ),( Hong Seog Seo ),( Dong Joo Oh ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1
Background:?Anemia is an aggravating factor of cardiovascular disease. However, it is controversial whether anemia itself has adverse impact on clinical outcomes of the patients with acute myocardial infarction (AMI) treated with percutaneous coronary intervention (PCI) with drug-eluting stents (DESs). Methods:?In this study, a total of 881 consecutive AMI patients underwent PCI between 2004 and 2010 were analyzed. Anemia was defined using WHO criteria: hemoglobin level <13 g/dL for men and <12 g/dL for women. The patients were divided into the two groups: the anemia group (n=349) and the non-anemia group (n=532). Six-month angiographic and 2-year major clinical outcomes were compared between the two groups. Results:?At baseline, the anemia group had more female, elderly, hypertension, diabetes mellitus, chronic renal-insufficiency, and higher levels of cardiac markers than the non-anemia group. At 6 months, major angiographic outcomes were similar between the two groups. The incidence of vascular complicat-ions during PCI and stent thrombosis were similar between the two groups. To adjust confounders, we performed propensity score matching (PSM) analysis, and after PSM, AMI patients with anemia had higher cumulative incidence of total death, cardiac death, recurrent myocardial infarction (MI), target lesion revascularization (TLR)-major adverse cardiac events (MACEs), and all MACEs up to 2 years. After PSM, multivariate analysis showed that the anemia was an independent predictor of death at 2 years?[adjusted OR; 2.5, CI; 1.3-4.9, p<0.001] Conclusions:?Anemia on admission in patients with AMI undergoing PCI with DESs was associated with higher individual and composite adverse cardiovascular events compared to those of AMI patients without anemia up to 2 years. Keywords:?Anemia, Myocardial infarction, Percutaneous coronary intervention
Radiculopathy as Delayed Presentations of Retained Spinal Bullet
Ryu, Bang,Kim, Sung Bum,Choi, Man Kyu,Kim, Kee D The Korean Neurosurgical Society 2015 Journal of Korean neurosurgical society Vol.58 No.4
Bullet injuries to the spine may cause injury to the anatomical structures with or without neurologic deterioration. Most bullet injuries are acute, resulting from direct injury. However, in rare cases, delayed injury may occur, resulting in claudication. We report a case of intradural bullet at the L3-4 level with radiculopathy in a 30-year-old male. After surgical removal, radicular and claudicating pain were improved significantly, and motor power of the right leg also improved. We report the case of intradural bullet, which resulted in delayed radiculopathy.