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천추 갈색종양(Brown tumor)으로 발현된 부갑상선 기능항진증 1예
홍우정,구본정,이재민,한상우,이효진,나소영,노흥규,김영건,송민호 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2
부갑상선 기능항진증에 의한 골병변으로 갈색종양이 있다. 갈색종양은 주로 장골을 침범하고 척추골에서의 발생은 매우 드물다. 국내의 보고에서 갈색종양의 장골 침범은 있었으나, 척추골에서의 발생은 보고된바 없다 .저자들은 부갑상선 기능항진증으로 인하여 척추골의 천추에 발생된 갈색종양 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. The bony involvement in primary hyperparathyroidism present as browm tumor or osteitis fibrosa cystica and lead to pathologic fracture. Brown tumor commonly involve long bone such as femur, tibia, fibula, humerus, and radius. Brown tumor of axial skeleton is a rare entity. Previously reported case that involve axial skeleton still not present. We report a 47-year-old male patient that he has a hyperparathyroidism presenting as brown tumor involving sacrum.
김영호,이화영,김선우,박형석,손희정,김재준,배상수,최규완,백승운,고광철,이풍렬,이종철,박정호,박상종,천정학,심상군,김창섭 대한소화기학회 1999 대한소화기학회지 Vol.34 No.6
Background/Aims: The aim of this study was to investigate predictive factors for malignant transformation of colorectal adenomatous polyps in Korea. Methods: One thousand five hundred and eighty- nine sessions of colonoscopic polypectomy were performed from November 1994 to September 1998 for 1,375 patients with adenomatous polyps at Samsung Medical Center. We analyzed the 2,179 adenomatous polyps including 55 (2.5%) polyps with malignant transformation, retrospectively. Results: Six parameters showed significant differences in univariate (p$lt;0.01) and multivariate analysis. For each parameter, the proportions of malignant polyps were as follows: for number of polyps, 1.3% in cases of single polyp and 10.3% in cases of multiple polyps; for size, 1.4% of polyps less than 1 cm and 15.5% of polyps larger than 1 cm; for location, 4.6% of the polyps located in rectum or sigmoid colon and 1.1% of the polyps located in descending to ascending colon; for morphology, 0.9% in polyps of Yamada type I/II and 7.6% in polyps of Yamada type III/IV; for underlying histology, 1.4% in cases of tubular adenoma and 8.1% in cases of tubulovillous or villous adenoma; for degree of dysplasia, 1.2% in cases accompanied with low-grade dysplasia and 8.9% in cases accompanied with high-grade dysplasia. Conclusions: The malignant potential of colorectal adenomatous polyps in Korea is correlated with multiplicity, distal location, pedunculated shape as well as well-known factors like size, histologic type and degree of dysplasia.