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A Study on Canadian-Sino Trade and Investment
Sun Zhong Wei(Zhong Wei Sun) 한국캐나다학회 2007 Asia-Pacific Journal of Canadian Studies (APJCS) Vol.13 No.1
Foreign trade and FDI(foreign direct investment) are the two routes to take part in the world economy competition and cooperation. This paper researches mainly on Canada’s foreign trade with China and Canada’s FDI in China. After reviewing China and Canada’s foreign trade and investment respectively, this paper concentrates on Canadian-Sino trade and Canada’s FDI in China. Under rapid growth of Canadian-Sino trade, the goods structure has changed along with China’s industrialization and development. This provides Canada a big opportunity and Challenge at the same time. At the back of soaring increase of Canada’s FDI in China, this paper does further research on the relation between Canada’s FDI in China and Canadian-Sino trade. By empirical analysis, the conclusion is paradox that the increase of Canada’s FDI in China leads to the decrease of the bilateral trade. Based on theory of OLI, this paper analyzes the reason that the fields of Canadian-Sino trade are different to the fields which Canada invested in China, and at the same time, explain the paradox well. This paper also predicts the future of Canadian-Sino trade and investment and gives some advices to Canada. At the end of this paper, some conclusions are drawn.
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Wang, Jing-Luan,Wu, Da-Wei,Cheng, Zhao-Zhong,Han, Wei-Zhong,Xu, Sheng-Wei,Sun, Ni-Na Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12
Objective: This study evaluated the expression level of high mobility group box-B1 (HMGB-1) and matrix metalloproteinase-9 (MMP-9) in non-small cell lung cancer (NSCLC) inmorder to reveal any relation with development and prognosis. Methods: NSCLC and normal tissues were selected from 30 patients at age of 30-73, and used for RT-PCR and Western blot analyses of HMGB-1. A total of 100 paraffin embedded NSCLC tissues were also isolated from patients through surgical resection, and used for detection of HMGB-1 by immunohistochemistry. In addition, 50 samples were also applied for MMP-9 detection, and 30 normal tissues were considered as controls. Correlation analysis of HMGB-1 and MMP-9 was carried out by Pearsons correlation coefficient. Results: The average expression level of HMGB-1 in NSCLC patients was significantly higher than in normal lung tissues. In addition, patients in III-IV period exhibit significantly higher positive rate of HMGB-1 when compared with I-II period cases. Furthermore, a positive correlation with HMGB-1 was found in the expression of MPP-9. Conclusion: HMGB-1 was highly expressed in NSCLC, which may become a prognostic and predictive marker for NSCLC. Besides, MPP-9 was positively correlated with HMGB-1.
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Cloning of OLR1 Gene in Pig Adipose Tissue and Preliminary Study on Its Lipid-accumulating Effect
Sun, Chao,Liu, Chun-wei,Zhang, Zhong-pin Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.10
In this study we cloned and characterized a novel lipid-accumulating gene, the oxidized low-density lipoprotein receptor 1 (OLR1), which is associated with lipogenesis. We analyzed the gene structure and detected the mRNA transcriptional expression levels in pig adipose tissues at different months of age (MA) and in different economic types (lean type and obese type) using real-time fluorescence quantitative PCR. OLR1 expression profile in different tissues of pig was analyzed. Finally, we studied the correlation between OLR1 and lipid metabolism related genes including peroxisome proliferator-activated $receptor{\gamma}2$ ($PPAR{\gamma}2$), fatty acid synthetase (FAS), triacylglycerol hydrolase (TGH), CAAT/enhancer binding protein $\alpha$ ($C/EBP{\alpha}$) and sterol regulatory element binding protein-1c (SREBP-1c). Results indicated that the OLR1 gene of the pig exhibited the highest homology with the cattle (84%), and the lowest with the mouse (27%). The signal peptide located from amino acid 38 to 60 and the domain from amino acid 144 to 256 were shared by the C-type lectin family. The expression level of OLR1 in pig lung was exceedingly higher than other tested tissues (p<0.01). In pig adipose tissue, the expression level of OLR1 mRNA increased significantly with growth (p<0.01). The expression level of OLR1 mRNA in obese-type pigs was significantly higher than that of lean-type pigs of the same monthly age (p<0.05). In adipose tissue, the expression of OLR1 correlated with $PPAR{\gamma}2$, FAS and SREBP-1c, but not TGH or C/EBP${\alpha}$. In conclusion, OLR1 was highly associated with fat deposition and its transcription, as suggested by high correlations, was possibly regulated by $PPAR{\gamma}2$ and SREBP-1c.
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Wei-Bin Ni,De-Hao Qiao,Hong-Wei Sun,Xu Zhang,Zhong-Wen Zhang,Shao-Jie Wang 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.2
Precast concrete frame structure with nonrectangular columns are becoming attractive to researchers and engineers owing to advantages such as avoiding column protrusion from walls and saving space. This paper presents the experimental investigation of a full-scale precast concrete frame structure with L-shaped columns (PCFS) subjected to reverse cyclic loading. The precast connection adopted grouted anchor connection. As a comparison and benchmark, one full-scale monolithic sample (RCFS) was also tested. The results indicates that the greater steel ratio in the grouted anchor connection region leads to a high local stiffness of the elements, which contributed to delaying occurrence of the first crack at the grouting holes. The failure mode, lateral load capacity, stiffness degradation, load-carrying capacity degradation, energy-dissipating capacity, ductility and interlayer residual deformation were compared between two specimens. PCFS specimen exhibited comparatively better hysteretic behavior, energy-dissipating capacity, residual deformation-resisting capacity and ductility. For RCFS and PCFS specimens, the peak load difference was within 7%. About 15% increases in ductility were observed for PCFS specimen compared with RCFS specimen. The test results would provide reference for the application of the precast concrete structure with nonrectangular columns in the new residential buildings.
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Crystalline ZnO thin film by hydrothermal growth
Sun, Ke,Wei, Wei,Ding, Yong,Jing, Yi,Wang, Zhong Lin,Wang, Deli Royal Society of Chemistry 2011 Chemical communications Vol.47 No.27
<P>In this work, we have successfully synthesised ZnO crystal thin film with a high quality from hydrothermal reaction on sapphire substrate. The growth mechanism is clarified based on an extensive XTEM study. In addition, electrical and optical properties of the crystal thin film, which can be controlled by impurities, are characterized. The synthesis technique provides fairly high quality and cost-effective substrates for optoelectronic and renewable energy applications.</P> <P>Graphic Abstract</P><P>The capability to control the structural/optical/electrical properties is enabled using a high quality ZnO thin film from solution for electronics and optoelectronics applications. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1cc11397f'> </P>
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Sun Di,Mou Shan,Chen Lifeng,Yang Jie,Wang Rongrong,Zhong Aimei,Wang Wei,Tong Jing,Wang Zhenxing,Sun Jiaming 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Background: Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have been found to have a great potential for soft tissue repair due to various biological functions, including pro-angiogenesis and low immunogenicity. However, the low yield and heterogeneity of MSC-EVs limited their clinical transformation. This study was designed to develop a novel adipose-derived stem cell engineered nanovesicles (ADSC-NVs) with high production and explore its pro-angiogenetic effect and application in adipose tissue regeneration. Methods: Adipose-derived stem cell-derived extracellular vesicles (ADSC-EVs) were isolated from an EVs-free culture medium for human ADSCs (hADSCs). ADSC-NVs were prepared by sequentially extruding ADSCs followed by iodixanol density gradient ultracentrifugation and were compared with ADSC-EVs in morphology, size distribution, protein contents and yield. The pro-angiogenetic effect of ADSC-NVs in different doses (0, 5, 20 and 80 μg/mL) in vitro was determined using transwell assay, tube formation assay, western blot and qRT-PCR. In vivo, BALB/c nude mice were administered injection of a mixture of fat granules and different dose of ADSC-NVs and grafts were harvested at 12 weeks post-transplantation for further analysis. By analyzing the weight and volume of grafts and histological evaluation, we investigated the effect of ADSC-NVs in vessel formation and adipose tissue regeneration. Results: Our results showed yield of purified ADSC-NVs was approximately 20 times more than that of ADSC-EVs secreted by the same number of ADSCs. In vitro, both ADSC-NVs and ADSC-EVs exhibited a dose-dependent proangiogenetic effect, despite their distinct miRNA profiles. These effects of ADSC-NVs may be mediated by enriched miR-21-5p via PTEN inhibition and PI3K/p-Akt signaling activation. Furthermore, after a mixed injection of ADSC-NVs, vessel formation and adipose regeneration were observed in vivo in fat implants. Conclusions: Our study developed a potent alternative of ADSC-EVs. ADSC-NVs have a high pro-angiogenesis potential and can be used as cell-free therapeutic biomaterials in soft tissue regeneration.
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Wang, Zhong-Tang,Wei, Li-Li,Ding, Xiu-Ping,Sun, Ming-Ping,Sun, Hong-Fu,Li, Bao-Sheng Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Objective: To investigate the treatment effect of additional information obtained by single photon emission computed tomography (SPECT) lung perfusion imaging (LPI) in the radiotherapy planning process for patients with stage III non-small cell lung cancer (NSCLC). Methods: 39 patients with stage III NSCLC were enrolled. Gross tumor volume (GTV) was outlined by SPECT/CT images, SPECT-LPIs being used to define functional lung (FL) and non-functional lung (NFL) regions. Two sets of IMRT plans were designed to deliver 64Gy to PTV. One was a regular IMRT plan using CT images only (Plan 1), and the other was a corresponding IMRT plan using co-registered images (Plan 2). $FL_{Vx}$ (the % volume of functional lung receiving ${\geq}$x Gy) and $WL_{Vx}$ (% volume of whole lung to receive ${\geq}$x Gy) were compared by paired Student's t test. Kendalls correlation was used to analyze the factor (s) related with the FLV20 decrease. Results: Compared with plan 1, both $WL_{Vx}$ and $FL_{Vx}$ were decreased in plan 2. $WL_{V10}$, $WL_{V15}$, $WL_{V20}$, $WL_{V25}$, $WL_{V30}$ and $WL_{V35}$ decreased 9.7%, 13.8%, 17.2%, 12.9%, 9.8% and 9.8%, and $FL_{V10}$, $FL_{V15}$, $FL_{V20}$, $FL_{V25}$, $FL_{V30}$ and $FL_{V35}$ decreased 10.8%, 14.6%, 17.3%, 14.5%, 14.5% and 10.5%. $FL_{Vx}$ decreased significantly compared with $WL_{Vx}$. There were significant differences in $WL_{V10}$, $WL_{V15}$, $WL_{V20}$, $WL_{V25}$, $WL_{V3}$ and $FL_{V10}$, $FL_{V15}$, $FL_{V20}$, $FL_{V25}$, $FL_{V30}$ between plan 1 and plan 2 (P=0.002, 0.000, 0.000, 0.005, 0.027 and 0.002, 0.000, 0.000, 0.006, 0.010). According to Kendall correlation analysis, NFL had a negative relation with the percentage FLV20 decrease (r=-0.559, P<0.01), while the distance of PTV and NFL center had a significantly positive relation with the percentage of FLV20 decrease (r=0.768, P<0.01). Conclusion: Routine use of SPECT-LPI for patients undergoing radiotherapy planning for stage III NSCLC appears warranted.
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