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2-[(4-Cyanophenyl)amino]-3-chloro-1,4-naphthalenedione (NQ-Y15)의 돌연변이원성
김봉희,정기화,유충규,창동신,이기선,전선덕,소동수,채상호,문창규 德成女子大學校 藥學硏究所 2001 藥學論文誌 Vol.12 No.1
2-[(4-Cyanophenyl)amino]-3-chloro-1, 4-naphthalenedione (NQ-Y15) was asssayed for its genotoxic potential by using Salmonella typhimurium reversion assay and in vitro chromosome aberration test on Chinese hamster lung cells. In the Ames test, NQ-Y15 induced his+revertants of Salmonella typhimurium TA 98 and TA 1537, reaching levels twice the negative control values. But, NQ-Y15 induced only his+revertants of Salmonella typhimurium TA 1537 more than twice the control values under the condition with metabolic activation system. In the cytogenetic test on chinese hamster lung cells. NQ-Y15 showed significant chromosomal aberrations, but the incidence was significantly reduced in the presence of metabolic activation.
2-[(4-Cyanophenyl)amino]-3-chloro-1,4-naphthalenedione(NQ-Y15)의 돌연변이원성
김봉희,정기화,유충규,창동신,이기선,전선덕,소동수,채상호,문창규 한국환경독성학회 2000 환경독성보건학회지 Vol.15 No.4
2-[(4-Cyanophenyl)amino]-3-chloro-1, 4-naphthalenedione (NQ-Y15) was asssayed for its genotoxic potential by using Salmonella typhimurium reversion assay and in vitro chromosome aberration test on Chinese hamster lung cells. In the Ames test, NQ-Y 15 induced his+ revertants of Salmonella typhimurium TA 98 and TA1537, reaching levels twice the negative control values. But, NQ-Y15 induced only his^(+) revertants of Salmonella typhimurium TA1537 more than twice the control values under the condition with metabolic activation system. In the cytogenetic test on chinese hamster lung cells, NQ-Y15 showed significant chromosomal aberrations, but the incidence was significantly reduced in the presence of metabolic activation.
Enhancing Cross-Cultural Adaptation Skills of International Chinese Language Teachers
Zhang Lin(Lin Zhang),Sun Yi(Yi Sun) 아시아사회과학학회 2023 Jornal of Asia Social Science Vol.10 No.2
Since 2004, China National Office for Teaching Chinese as a Foreign Language began dispatching international Chinese language teachers to countries in need around the world, the teachers have made important contributions to international Chinese language education and cultural communication. International Chinese language teachers are bound to face various discomfort and difficulties when working and living in a cultural environment different from their own, which affects both their teaching and personal life. This paper attempts to analyze the internal and external factors that affect the teachers’ cross-cultural adaptability, as well as the deficiencies in pre-job training for international Chinese language teachers, to find the existing problems and make suggestions to solve them.
Wenfeng Zhang,Jianfeng Wang,Cheng Sun,Ting Zhang,Xueying Zhang,Tao Zhang 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.10
The induced magnetic anisotropy, domain structure and magnetic properties of nanocrystallized Fe72.9Si15.8B6.9Nb3.2Cu1Co0.2 materials by continuous stress-annealing at 803–903 K under 0–75 MPa were systematically investigated. It was found that the tensile stress applied during annealing is beneficial to reduce the coercivity and core loss by refining the grain size of α-Fe phase. The remanence and permeability for the annealed samples at 853–903 K are negatively correlated with the induced anisotropy, which increases with the applied tensile stress. The stress-annealed samples yield magnetic easy plane perpendicular to the stress axis with an induced anisotropy constant greater than 1200 J/m3. The nanocrystalline cores with a low AC coercivity of 6.0 A/m and low core loss of 16.1 W/kg in combination with a high DC bias capability was successfully fabricated by stress-annealing the amorphous precursor at 878 K under 40 MPa. The current nanocrystalline material has potential for the application as anti-DC transformers in the electronic field.
Huaqin Sun,Qiang Gu,Sundaram Kuppu,Li Sun,Xunlu Zhu,Neelam Mishra,Rongbin Hu,Guoxin Shen,Junling Zhang,Yizheng Zhang,Longfu Zhu,Xianlong Zhang,Mark Burow,Paxton Payton,Hong Zhang 한국식물생명공학회 2013 Plant biotechnology reports Vol.7 No.3
The Arabidopsis gene AVP1 encodes an H?-pyrophosphatase that functions as a proton pump at thevacuolar membranes, generating a proton gradient acrossvacuolar membranes, which serves as the driving force formany secondary transporters on vacuolar membranes suchas Na?/H?-antiporters. Overexpression of AVP1 couldimprove drought tolerance and salt tolerance in transgenicplants, suggesting a possible way in improving drought andsalt tolerance in crops. The AVP1 was therefore introducedinto peanut by Agrobacterium-mediated transformation. Analysis of AVP1-expressing peanut indicated that AVP1-overexpression in peanut could improve both droughtand salt tolerance in greenhouse and growth chamberconditions, as AVP1-overexpressing peanuts producedmore biomass and maintained higher photosynthetic ratesunder both drought and salt conditions. In the field, AVP1-overexpressing peanuts also outperformed wild-type plantsby having higher photosynthetic rates and producing higheryields under low irrigation conditions.
Wen-Yi Zhang,Xin-Ze Xiao,Chao Lv,Jia Zhao,Gong Wang,Xuan Gu,Ran Zhang,Bin-Bin Xu,Dan-Dan Zhang,Ai-Wu Li,Yong-Lai Zhang,Hong-Bo Sun 한국고분자학회 2013 Macromolecular Research Vol.21 No.3
Reported here is the fabrication of photopolymer hierarchical micronanostructures through a combinative process of electrospinning and subsequent photolithography. Electrospun SU-8 (epoxy-based negative photoresist)nanofiber films have been patterned into gratings with periods of 100, 200, 300, and 400 μm, respectively. Deposition of a silver nanolayer on these interlaced nanofiber films would lead to the formation of various plasmonic nanostructures,and therefore, giving rise to abundant surface-enhanced Raman scattering (SERS) “hot spots”. In the detection of Rhodamine 6G (R6G), probing molecule, the resultant SERS substrates show both high sensitivity and good reproducibility. The SERS enhancement factor could reach as high as ~108, indicating high efficiency. The fabrication of patterned, highly efficient SERS substrates may hold a great promise for the integration of SERS substrates in various microdevices such as microfluidic chips.
Study on economic performances of multi-span suspension bridges part 2: parametric study
Zhang, Li-Wen,Xiao, Ru-Cheng,Sun, Bin,Jiang, Yang,Zhang, Xue-Yi,Zhuang, Dong-Li,Zhou, Yun-Gang,Tu, Xue Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.47 No.2
Economic performances of consecutive multi-span suspension bridges are studied. The material amount and cost estimation formulas of the bridges have been derived in the part 1 of the study. A parametric study is carried out based on the formulas for investigating the different factors' effect on the bridge cost. The factors include the bridge sag, the bridge span, the bridge foundation and the environment condition, etc. Then, an economical layout of the bridges is proposed for different conditions. Lastly, a selection of suspension bridge types is discussed based on the economy of bridges.
Association Between XRCC1 Gene Polymorphisms and Risk of Glioma Development: A Meta-analysis
Sun, Jian-Ying,Zhang, Chun-Yang,Zhang, Zhen-Jun,Dong, Yan-Fang,Zhang, An-Long,Wang, Zhi-Wei,Mei, Xiao-Long Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9
Objective: Previous studies of the association between X-ray cross-complementing group 1 (XRCC1) gene polymorphisms and the gliomas risk have yielded conflicting results, and thus a meta-analysis was performed to provide a more accurate estimation. Methods: A computerized literature search of 5 electronic databases was conducted to identify the relevant studies. Fixed or random effect models were selected based on the heterogeneity test. Publication bias was estimated using Begg's funnel plots and Egger's regression test. Results: A total of 11 studies (3,810 cases and 6,079 controls), 7 studies (2,928 cases and 5,048 controls), and 4 studies (1,461 cases and 2,593 controls) were finally included in the analyses of the association between XRCC1 Arg399Gln, Arg194Trp, and Arg280His polymorphisms and glioma risk, respectively. The pooled results showed that GlnGln carriage was associated with moderately increased risk of gliomas in Asians (GlnGln vs. ArgArg, OR=1.490, 95%CI 1.031-2.153; GlnGln/ArgGln vs. ArgArg, OR=1.321, 95%CI 1.037-1.684), whereas a marginal association was revealed in Caucasians. For the Arg194Trp polymorphism, although a significant association was shown in the homozygous genotype comparisons (TrpTrp vs. ArgArg, OR = 2.209, 95%CI 1.398-2.945), no significant link was found on subgroup analysis stratified by ethnicity. With regard to the Arg280His polymorphism, no significant association was found in each comparison. No particular study was found to significantly influence the pooled results, and no potential publication bias was detected. Conclusions: This meta-analysis suggested that the XRCC1 Arg399Gln polymorphism is moderately associated with increased risk of gliomas in Asians, while Arg194Trp and Arg280His polymorphisms demonstrated no significant influence. Due to the limited studies and the potential confounders, further studies are needed to confirm these results.
Performance investigation of nanoscale thermal cloak by the perforated silicon film
Zhang Jian,Zhang Haochun,Zhang Dong,Sun Wenbo,Li Yiyi 한국물리학회 2022 Current Applied Physics Vol.35 No.-
In recent years, nanoscale thermal cloak, as a representative of nanoscale heat flux regulation devices, has attracted a lot of attention from researchers. However, the existing design methods are relatively complicated and all adopt constant temperature boundaries, the temperature changes constantly in the real environment, which greatly hinders its engineering applications. In this paper, inspired by phonon localization theory, we construct a nanoscale thermal cloak by a perforated silicon membrane and evaluate its cloaking performance and dynamic response. Results show that when the perforated area is fixed, the more the number of holes, the better the cloaking performance. In addition, the nanoscale thermal cloak still exhibits good cloaking performance in the dynamic environment. Finally, the cloaking mechanism is analyzed by calculating the phonon density of states (PDOS) and mode participation rate (MPR), and the reduction of thermal conductivity in the functional region is attributed to phonon localization.