患者에서 分離한 腸內細菌(大腸菌)에 대한 血淸型 및 抗生劑 耐性傳達에 관한 硏究

김승곤,최성민 서울保健大學 1994 論文集 Vol.14 No.1

This study was undertaken the biochemical characteristics, serotyping and antibiotics susceptibility to 79 strans of Escherichia coli isolated from patient from march in 1993 to December in 1993. Of 79 isolates, thirty one isolates(39.2%) were idenfied by pathogenic E. coli immune sera producted by Denka Seiken. Among them, 9 isolates(11.4%) were 06, followed by 015 and 044(4 isolates, 12.9%), respectively. 018, 0114, 0119, 0125, 0146, 0153 and 0164 were identified 1 isolate(3.2%), repectively. Resistance rate of E. coli isolated from patients against 12 antibiotics were 86.1%(68 isolates). Of them, resistance rate against TC was 68.3%(54 isolates), AM 64.4%(51 isolates), CB 62.0%(49 isolates), NN and NA 8.9%(7 isolates) and PB 1.3%(1 isolate), respectively. Of 68 resistant isolates, 59 isolates(86.8%) were resistant to more than 2 drug, followed by 2 drugs-resistance pattern01 isolates, 16.2%), 3 drug and 6 drig resistance pattern(9 isolates, 13.2%). Of multipleresistance pattern, AM-CB-SM and AM-CB-SM-TE pattern were most frequent(5 isolates, 7.4%, respectively) and more than 10 drugs resistance pattern was 1 isolate. Of 68 resistant isolates, 42(61.8%) were transferred their resistance to recipient cell (E. coli ML1410Na^(r)), Of them, the most frequently multiple transferred drugs was 2 drugs(40.5%, 17isolates) and the most frequently multiple transferred pattren was AM-CB(23.8%. 10 isolates).

연폭로 근로자들에서 적혈구 Pyrimidine 5'-Nucleotidase 활성도 및 요중 N-Acetyl-β-D-Glucosaminidase 활성도와의 상관관계 연구

서홍규,이병국,황천현,장성훈,이성수,이원진,최재욱 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.2

In this study, we measured the activity of the erythrocyte pyrimidin 5'-nuclectidase(P5N) and urinary N-acetyl-β-D-glucosaminidase(NAG) from 154 workers exposed to lead and 43 workers not exposed. We analyzed the correlation of the P5N activity and NAG activity with other biololgical exposure indices of lead such as blood lead(PbB) and zinc protoporphyrin(ZPP). The measurement was performed by using high performance liquid chromatography(HPLC), spectrophotometer and atomic absorption spectrophotometer. The results are as follows : 1. The mean value of P5N activity for workers exposed to lead was 9.50±3.13 μmol uridine/hr/g Hb and 11.60±2.2 μmol uridine/hr/g Hb for workers not exposed. The P5N activity showed a normal distribution, but the other indices of lead showed logarithmic normal distributions. 2. The P5N activity and ZPP were decreased as PbB was increased. But the NAG activity had no correlation with changes of PbB. 3. The correlation coefficients of the P5N activity with other biological exposure indices of lead such as PbB, ZPP, NAG activity were -0.72, -0.55, and 0.05, respectively. We speculated that the P5N activity can be used as a reliable biological exposure index of lead but NAG activity can be used as a biological management index of lead.

모 중장비 제조 사업장의 유해작업요인 평가에 관한 연구

장성훈,이원진,서창호,김종규,이영신,황천현,서동윤 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.6 No.-

We evaluated the types and the amount of hazards in a heavy equipment factory and a plant factory to improve workers' health and to determine the priority in occupational health programs. We first inspected the working processes to find hazardous agents, measured them in each process environment, and compare the results with their TLVs(Threshold Level Value). This study was carried out from December 26, 1995 to January 30, 1996. The results are as follows: 1. In two factories, we identified the following hazardous agents: noise, dust, heavy metal fume, organic solvents, illumination, gases and ultraviolet light. 2. In the heavy equipment factory, some agents were over their TLVs in the following departments. 1) Preparation Department: dust, Pb, Mn, Fe₂O₃, NO₂ 2) Manufacture Department: noise, dust, Pb, Mn, Fe₂O₃, NO₂ 3) Assembly Department: noise 4) Technique Department: NO₂ 3. In the plant factory, some agents were over their TLVs in the following departments: 1) 1 Bay: illumination, Pb, Mn, Fe₂O₃ 2) 2 Bay: dust, illumination, Cu 3) 3 Bay: illumination 4) 4 Bay: noise, dust, Pb, Mn, Fe₂O₃, NO₂ 5) 5 Bay: noise, dust, Pb, Mn, Fe₂O₃, NO₂ 6) 6 Bay: Pb, Mn, NO₂ We concluded that the hazardous agents such as heavy metal fume, noise and noxious gas were required to be controlled at first.

의료기관의 의료시혜 확대 및 사회복지 서어비스 제공에 관한 모형연구

김성이,김융일 聖心女子大學校 1981 論文集 Vol.12 No.1

The purpose of this study is to establish a model for enlargement of medical services as well as social services in rural areas by community medical centers. In rural areas the level of medical services is very low in terms of quality and quantity because of the concentration of medical personnel and facilities in urban areas which has resulted from the low level of financial ability of rural residents, the high cost of medical care, and the prepayment system for medical services. However, it has been recently pointed out that the lower level of medical personnel and facilities is not fully utilized because of mismanagement. Furthermore, the medical delivery system is not integrated into other social agencies and services. Therefore, the major purpose of this study is to suggest a basic practical and theoretical concept for a medical delivery system. To achieve this end, two research methods were used. One is a Field study examining the current situations and system of four leading community medical service centers such as the Korean Community Medical Cooperation's Sabook Medical Center, the Asan Social Welfare Program Foundation's Inje Medical Center, the Korean Health Development Institute's Hong Chun Medical Center, and Yeonsei University's Kang Hwa Medical Program Center. The other is a survey of all the households in Wontong 7th Ri and Hange 2nd Ri areas which are covered by the Asan Social Welfare Program Foundation's Inje Medical program in order to develop a model and to examine the effectiveness of this medical program. These collected data were analyzed by association analysis such as Kendall's Tau as well as the descriptive analysis such as a frequency test and cross tabsulation methods. The delivery system's theoretical framework is based on the primary health care concept. The primary health care concept is to integrate medical services into social services in order to improve living conditions. Therefore, the primary health care program consists of a family health care program, human development services, and a community development program. These three major parts are closely interrelated. Therefore, the three parts should be brought under one system to increase effectiveness. Thus the community medical center should give these three kind of services for residents as well as for the agency itself. In order to carry out the above basic concept, the service centers should perform the following roles: First, the center should try to gather the material and non-material resources from the communitie agencys and the residents. Second, the center should gather the medicalresources through rational management of the center's medical manpower and facilities. Third, the center should use the community's combined resources for purposeful development of the community. Last, the center should use the combined resources from the center itself for enlargement and maintenance of the center. The four reles of the center seem to be the successfully carried out in a county unit, in other words, in county medical centers or hospitals in county areas. Furthermore the county medical center should be integrated into private hospitals in terms of function (which may be called the community medical center). In order to perform the four functions the community medical center should manage and control the organization which is composed of the residents, the community agencies and the government branches. For example, committees for sponsoring community affairs, administrative cooperation committees and medical insurance organizations should be controlled by the community medical center. The next important thing to be considered is the principle of closing the gap between the community medical center and the residents. This role is taken over by primary care centers and village health workers. The primary care centers should be located in areas where the residents have difficulty reaching medical care for lack of transportation. The village health worker has the function as innovator of changing the residents' health awareness and behavior as well as being a first aid helper. Therefore, the village health worker is selected from people who are respected and are active participants in village affairs. In summary, the whole medical delivery system can be classified into two parts: one is the main office's system and the other is the connections system the main office system and the residents. The main office system is composed of the community service department. The connection system is composed of the primary health center and the village health worker. The primary care center does the functions which are delegated from by the main office in those areas where the main office directly serves the residents. The village health worker's major role is to influence the opinion of residents on health. The suggested conceptual model was checked partly by other researchers and authors of this study. The results of this research show the positive effects of this system. Therefore, if the suggested model is used over a given period of time, the community medical services would be expanded and achieve their purposes.

矩形斷面水路의 亂流構造解析

朴成天,李三魯,文炳錫,李英錫 여수대학교 1989 論文集 Vol.3 No.-

The study, in a rectangular open channel, has carried out highly sccurate measurements of secondary currents of straight flows by making use of Hot-wire Anemometer system. The effect of primary and secondary velocity distribution, turbulence intensity, Reynolds-stress distribution, friction velocity by free-surface were investigated. As the results, (1) The maximum-velocity appears at Y??/H=0.6 under surface, the contour lines of velocity show the projecting form in the direction of the side-wall. (2) The limited friction velocity satisfactorily estmated logarithemic method around the side-wall, a friction velocity is distributed the reflection of secondary current. (3) The turbulence degree of strength(u') increases as one goes on along the direction of free-surface, but v' decreases. (4) Reynolds-stress appears a negative field near the free-surface.

Cation基의 분포가 다른 Cationic Polyacrylamides(C-PAM)의 펄프에의 흡착성 : 흡착시간의 영향에 대하여

朴成培,趙鍾洙,尹承洛,田中浩雄 진주산업대학교 농업기술연구소 1999 農業技術硏究所報 Vol.12 No.-

The adsorption of two cationic polyacrylamides (C-PAM), with similar molecular weights (MW) 5.3·10^5 and 5.1·10^5 and charge density (CD) 1.19 and 1.25 meq/g but with different distribution of cationic groups respectively has been studied. There are two kinds of substrates ; one is cellulose fiber without fine fraction, and the other is cellulose fibers with fine fraction. At the stirring speed used, the adsorption of these C-PAMs onto cellulose fibers was rapid regadless of cationic distribution, and the adsorption amount of C-PAM with homogeneous cationic distribution was a little greater than that with heterogeneous cationic distribution. This small difference is probably due to the existence of irregularities on the surface of cellulose fibers and the greater diffusion of the C-PAM with homogeneous cationic distribution. That only a small difference is observed is due primarily to the strong attraction between opposite charges. The adsorbed amounts of C-PAM gradually increased both for cellulose fibers, most rapidly for Cellulose fibers with fine fraction and most slowly for Cellulose fibers without fine fraction. These results can be attributed to the porous nature of the cellulose fibers and the adsorption area of the fine fraction.

돼지의 세균성 설사증에 대한 항균펩타이드(Buforin Ⅱb)의 야외효능 실험

권성균,이완규 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.2

The objectives in the present study were to evaluate the therapeutic effect of antimicrobial peptide (Buforin Ⅱ b) against piglet diarrhea in the field test. Experiment was conducted to evaluate the efficacy of Buforin Ⅱb on piglets having diarrhea with two treatments; Treatment A (2 mg of Buforin Ⅱ b/ml) and Treatment B (4 mg of Buforin Ⅱb/ml). Changes in body weight, average daily gains, diarrhea index and shedding of hemolytic E. coli were monitored for the experimental period under field conditions. In this study ( n= 40 pigs), Treatment A and B group reduced diarrhea index(p<0.01, p<0.001) and shedding of hemolytic E. coli, and increased body weight and average daily gain, compared to the Control(+) group. This study indicated that Buforin Ⅱb had therapeutic effect and possibility for treatment in piglets having diarrhea.

韓國産 파리의 硏究 第18報 腐肉에 誘引된 파리類에 關하여 : 慶北大學校 캠퍼스 한 곳을 對象으로 At a site on the Kyungpook University campus

朴星湖,孫錫洛 慶北大學校 1982 論文集 Vol.33 No.-

1. A total of 8,434 flies were collected by the fly trap laid in the Kyungpook university campus on 28 separate occasion over a eight-month period. The collection comprised 21.7% males and 78.3% female at male-to-female sex ratio of 29.5. 2. The catches were identified and classified into 22 species: Calliphora lata Pierretia ugamskii Aldrichina grahami Ravinia striata Phaenicia sericata Musca domestica P. cuprina M. tempestiva Lucilia illustris Muscina stabulans Parasarcophaga similis M. angustifrons P. crassipalpis Fannia canicularis P. albiceps F. scalaris P. harpax Ophyra leucostoma Helicophagella melanura Anthomyia illocata Boettcherisca peregrina Graphomyia maculata 3. Of the 22 species, eight were of sanitary significance occurring in numbers exceeding 80. Arranged in the descending order in size of the catches: Lucilia, Phaenicia spp. 53.8% of the total collection (at sex ratio of 8.9), Fannia scalaris 11.2% (64.9), Aldrichina grahami 8.8% (93.2), Boettcherisca peregrina 6.6%, Ophyra leucostoma 4.9%(7.9), Muscina angustifrons 4.0%(21), Calliphora lata 2.7%(21.5) and Helicophagella melanura 1.9%. 4. As seasonal prevalence common among the species collected five times in 26 April, 24 May, 5 July, 27 September and 25 October while the least occurrences were observed in 17 May and 4 October. 5. Temperature and the length of sunlight hours, among the environmental factors, appeared closely related to the sized of the catches. 6. The five most frequently occurring species of sanitary significance, paragraph four above, were paired into four groups in terms of the similarity in their seasonal prevalence: Calliphora lata and Aldrichina grahami, Boettcherisca peregrina and Helicophagella melanura, Phaenicia, Lucilia spp. and Ophyra leucostoma, and Muscina stabulans and M. angustifrons. 7. Many similarities were observed in the seasonal prevalences of the flies collected simultaneously at a site on the Kyungpook University campus and at a hog and chicken raising farmhouse lacated in Gosan in the suburbs of Daegu. 8. Among the catches collected at the both sites, Phaenicia, Lucilia spp. prevailed the most at 53.8% on the Kyungpook University campus and 38% at the farmhouse of Gosan. 9. The seasonal prevalences of the five most dominant species collected at the both sites were compared.

정보의 보존성과 자유의식 : For Integrate Understanding between Neuroscience and philosophy 신경과학과 철학의 통합적 이해를 위해

이성훈 大韓神經精神醫學會 1993 신경정신의학 Vol.32 No.3

This is written to elucidate relationship between neuroscientific and psychiatric approach to information and consciousness and philosophical approach to cognition and existence. Information endeavors to preserve itself through possession of a self of its own, and defensive information is added to pure information because such ability to preserve causes disturbance in proper information processing. What is needed to overcome this disturbance is consciousness. Consciousness is essentially an unpreserving and non-informative existence, and it is through such unpreserving function that conflict and irony of information processing are conquered. This process is analogous to that which tries to properly perceive phenomenon(information) itself through pure consciousness in the phenomenology. Moreover, pure informations obtained by way of unpreserving function of consciousness are developed into its own proper information through concentration and integration within consciousness, and this can be regarded as similar to the concept of the intentionality of consiousness of phenomenology. The domination relationship between the preservative self of information and the self of consciousness can be understood from the ontological viewpoint It can be viewed that the process of integration into being through nonbeing, where self of consciousness is freed from subordination to preservative self of information, presents a possibility of encountering ontology of philosophy. It is considered that a new possibility can be uncovered for the phenomena of neuroscience and psychiatry to meet with philosophical reasons through such relationship between information and consciousness.

충주시 농촌지역 주민의 건강행태 및 의료이용

장성훈,이건세,이원진,박종태 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.6 No.-

To evaluate the health behavior and medical utilization patterns of residents in Choongju rural area is useful for district health authority and health facilities in identifying the problems and setting the priorities. The reason is that rural area in Choongju city has a relatively few health resources except public health subcenters and public health posts. We evaluated the health behavior, health status, and medical utilization pattern of people in Choongju rural area using the household survey in summer, 1995. From 12 Myuns, randomly selected 6 Myuns first, and then applied convenient sample method. The residents had many health problems. 98(32%) out of the 307 respondents had some health problems, most of which were musculoskeletal and gastro-intestinal problems. A total of 218 persons(72%) thought that it was individual responsibility. Because the Lay referral system was poor and many of residents had to make the decisions about their health problems and medical seeking by themselves. When they were ill, 34% of respondents answered that they would visit hospitals first, and 24% would visit health-subcenter. But, when illness was severe, 72% of respondents answered that they would use hospitals at first. We suggest that public health facilities in rural area should be activated since they play the major role in promoting the health of rural residents. Health programmes such as health education, counseling, and disease prevention program, are also necessary especially for most of elderly persons.