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Soon Sung Lim,Hye Mi Kim,Sun Young Kim,Young Eun Jeon,Yeon Sil Lee,Il-Jun Kang 한국식품과학회 2009 Food Science and Biotechnology Vol.18 No.1
The inhibition effects of an Alpinia officinarum (AO, Zingiberaceae) on the formation of advanced glycation end products, aldose reductase, and scavenging effect on 1,1-diphenyl-2-picryl-hydrazil (DPPH) radical for the prevention and/or treatment of diabetic complications were investigated. The ethyl acetate fraction of AO was the most effective among all fractions. Through the tests with electron impact-mass spectrometry and nuclear magnetic resonance, two compounds (compound 1 and 2) finally obtained from the ethyl acetate fraction of AO were identified as galangin (1) and kaempferide (2), respectively. In addition, the compound 1 and 2 and the ethyl acetate fraction were compared for the prevention effect on advanced glycation end products, aldose reductase, and the scavenging effect on DPPH radical. The ethyl acetate fraction was significantly more effective than the 2 compounds for those preventive activities.
Lim, Jin-ah,Kim, Dong Hyun,Yoon, Yeoil,Jeong, Soon Kwan,Park, Ki Tae,Nam, Sung Chan American Chemical Society 2012 ENERGY AND FUELS Vol.26 No.6
<P>Aqueous potassium salt solutions of <SMALL>l</SMALL>-alanine and <SMALL>l</SMALL>-proline were investigated as carbon dioxide (CO<SUB>2</SUB>) absorbents. The CO<SUB>2</SUB> absorption capacities and absorption heats (−Δ<I>H</I><SUB>abs</SUB>) of the aqueous amino acid salts were measured in a semi-batch absorption system and differential reaction calorimeter (DRC). The solution experiments tested concentrations of 2.5 M and were carried out at 298 and 313 K. The <SUP>13</SUP>C and <SUP>1</SUP>H nuclear magnetic resonance (NMR) spectra were used to identify the species distributions in the CO<SUB>2</SUB>-loaded absorbents. The absorption properties were compared to those of the commercial monoethanolamine (MEA) absorbent, revealing that the CO<SUB>2</SUB> loading capacity was higher than that of MEA (0.68 mol of CO<SUB>2</SUB>/mol of solute for the potassium salt of <SMALL>l</SMALL>-alanine > 0.5 mol of CO<SUB>2</SUB>/mol of solute for MEA). The absorption heat was lower than that of MEA at 298 K (53.26 kJ/mol of CO<SUB>2</SUB> for the potassium salt of <SMALL>l</SMALL>-alanine < 81.77 kJ/mol of CO<SUB>2</SUB> for MEA).</P>
Convexity-based sequential track resource allocation for a phased array radar
Soon-Seo Park,Dae-Sung Jang,Han-Lim Choi 제어로봇시스템학회 2018 제어로봇시스템학회 국제학술대회 논문집 Vol.2018 No.10
This paper presents optimal resource allocation for multi-target tracking with a phased array radar. To fully exploit the radar potential, the resource manager must allocate resource to tasks in a way which maximises performance. Especially, the track tasks are required to be executed to consider expected tracking performance while utilizing limited time resource. Thus, in this paper, we propose sequential resource allocation algorithms for multiple track tasks that ensure optimality under a justifiable convexity assumption. The proposed algorithms are validated on a ballistic objects tracking example.
Effects of Proton on Lysolipid-induced Actions in OGR1-subfamily GPCRs
( Sung Mee Lim ),( Dong Soon Im ) 한국응용약물학회 2007 Biomolecules & Therapeutics(구 응용약물학회지) Vol.15 No.1
Lysolipids such as lysophosphatidylcholine (LPC), sphingosylphosphorylcholine (SPC), galactosyl-sphingosine (psychosine) have been matched as ligands for OGRI-subfamily G-protein-coupled receptors (GPCR), consisted of OGRl, GPR4, G2A, and TDAG8. Recently, those members of GPCRs have been reported as proton-sensing GPCRs. We used Jurkat T cells, which express four members of OGRI subfamily GPCRs endogenously to investigate effects of proton on lysolipid-induced several cellular events. We found no significant effect of proton on the lysolipid-induced Ca2+ increase and ROS production in Jurkat T cells. Further investigation is necessary to clarify the relationship of lysolipid and proton on the OGRI-subfamily GPCRs.
( Sung Yong Oh ),( Suee Lee ),( Sung Hyun Kim ),( Ji Hyun Lee ),( Hyo Jin Kim ),( Jung Hun Kang ),( Soon Il Lee ),( Young Mi Seo ),( Young Jin Choi ),( Min Jae Park ),( Moon Jin Kim ),( Ho Yeong Lim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: By defi nition, primary adenocarcinoma of the bladder (PAB) is a malignant neoplasm derived from urothelium of the bladder showing histologically pure glandular differentiation.Because of its rarity, role of chemotherapy for metastatic PAB is still questionable. Therefore, we performed a retrospective analysis of the clinical features and chemotherapy outcomes of metastatic PAB. Methods: Eligible patients for this retrospective analysis were initially diagnosed with adenocarcinoma and presented with a clinically no other primary site of origin. Unifi ed case report forms were provided to participating institutions. Results: We retrospectively reviewed 27 patients who treated with chemotherapy as metastatic PAB at nine Korean medical institutions from 2004 to 2014.The median age of patients was 58 years (range, 26 to 78 years) and 51.9% of the patients were female. Fourteen patients were urachal adenocarcinoma. Of 25 symptomatic patients, 19 experienced gross hematuria. Ten patients had two or more metastatic sites of the lungs (48.1%), peritoneum (33.3%), and ovary (22.2%), as the most common sites. Eleven patients were treated with 5-FU based chemotherapy, 4 were gemcitabine based, 3 were taxane and adriamycin based, and others. 13 of them achieved CR (14.8%) or PR (33.3%). Median PFS and OS for all patients were 10.6 months (95% confi dence interval [CI], 9.6 to 11.6 months) and 23.5 months (95% CI, 13.6 to 33.4 months), respectively. In the prognostic factor analysis, the cases of urachal adenocarcinoma had worse tendency in PFS and OS (p=0.058 and P=0.113, respectively). Conclusions: Metastatic PAC is a highly aggressive form of bladder cancer. Despite most of chemotherapy, PFS and OS were short, however, there were some long-term survivors, therefore, additional research on the predictive markers of several clinical, pathological differences and their treatments will be needed.
Lim, Sang-Soon,Kim, Ju-Heon,Kwon, Beomjin,Kim, Seong Keun,Park, Hyung-Ho,Lee, Ki-Suk,Baik, Jeong Min,Choi, Won Jun,Kim, Dong-Ik,Hyun, Dow-Bin,Kim, Jin-Sang,Baek, Seung-Hyub Elsevier 2016 JOURNAL OF ALLOYS AND COMPOUNDS Vol.678 No.-
<P><B>Abstract</B></P> <P>As a field-assisted technique, spark plasma sintering (SPS) enables densification of specimens in a very short period of time compared to other sintering techniques. For high performance thermoelectric material synthesis, SPS is widely used to fabricate nanograin-structured thermoelectric materials by rapidly densifying the nanopowders suppressing grain growth. However, the microstructural evolution behavior of thermoelectric materials by SPS, another important process during sintering, has been rarely studied. Here, we explore SPS as a tool to control the microstructure by long-time SPS. Using p-type (Bi<SUB>0.25</SUB>Sb<SUB>0.75</SUB>)<SUB>2</SUB>Te<SUB>3</SUB> thermoelectric materials as a model system, we systematically vary SPS temperature and time to understand the correlations between SPS conditions, microstructural evolution, and the thermoelectric properties. Our results show that the relatively low eutectic temperature (∼420 °C) and the existence of volatile tellurium (Te) are critical factors to determine both microstructure and thermoelectric property. In the liquid-phase sintering regime, rapid evaporation of Te leads to a strong dependence of thermoelectric property on SPS time. On the other hand, in the solid-phase sintering regime, there is a weak dependence on SPS time. The optimum thermoelectric figure-of-merit (Z) of 2.93 × 10<SUP>−3</SUP>/K is achieved by SPS at 500 °C for 30 min. Our results will provide an insight on the optimization of SPS conditions for materials containing volatile elements with low eutectic temperature.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Spark plasma sintering (SPS) is used to synthesize the thermoelectric (Bi<SUB>0.25</SUB>Sb<SUB>0.75</SUB>)<SUB>2</SUB>Te<SUB>3</SUB>. </LI> <LI> Liquid phase and volatile element are a key for the microstructure and thermoelectric property. </LI> <LI> Thermoelectric figure-of-merit of 2.9 × 10<SUP>−3</SUP>/K is achieved at 500 °C for 30 min. </LI> </UL> </P>
Lim, Jong-Sung,Jung, Mee-Kum,Kim, Mi-Soon,Ahn, Jae-Hyung,Ka, Jong-Ok The Microbiological Society of Korea 2004 The journal of microbiology Vol.42 No.2
Twelve mecoprop-degrading bacteria were isolated from soil samples, and their genetic and phenotypic characteristics were investigated. Analysis of 16S rDNA sequences indicated that the isolates were related to members of the genus Sphingomonas. Ten different chromosomal DNA patterns were obtained by polymerase-chain-reaction (PCR) amplification of repetitive extragenic palindromic (REP) sequences from the 12 isolates. The isolates were found to be able to utilize the chiral herbicide meco-prop as a sole source of carbon and energy. While seven of the isolates were able to degrade both (R)-and (S)-mecoprop, four isolates exhibited enantioselective degradation of the (S)-type and one isolate could degrade only the (R)-enantiomer. All of the isolates were observed to possess plasmid DNAs. When certain plasmids were removed from isolates MPll, MP15, and MP23, those strains could no longer degrade mecoprop. This compelling result suggests that plasmid DNAs, in this case, conferred the ability to degrade the herbicide. The isolates MP13, MP15, and MP24 were identified as the same strain; however, they exhibited different plasmid profiles. This indicates that these isolates acquired dif-ferent mecoprop-degradative plasmids in different soils through natural gene transfer.
Effect of Garlic on Serum Lipids Profiles and Leptin in Rats Fed High Fat Diet
Soon Ah Kang,Ho Jung Shin,Ki-Hyo Jang,Sung Eun Choi,Kyung Ah Yoon,Jin Sook Kim,Hye Kyung Chun,Yoongho Lim 한국식품영양과학회 2006 Preventive Nutrition and Food Science Vol.11 No.1
Although garlic has been reported to have impressive effects in lowering serum lipids, there have been controversial evaluations on these effects. To find the potential fator causing the inconsistency in the previous studies, we examined the effects of two types of garlic according to the producing-area (hangihyung garlic, nangihyung garlic) on serum lipid profiles and leptin level. Thirthy six of 4 wk old Sprague Dawley male rats fed high fat diet (40% of calories as fat) for 6 wks to induce obesity, and subsequently fed 5% garlic powder supplemented (HF+H: hangihyung garlic powder, HF+N: nangihyung garlic powder) high fat diets (w/w) for further 5 wk. For the comparison, normal control group fed AIN-76A diet (11.7% of calories as fat). Supplementation with hangihyung and nangihyung garlic resulted in a significant reduction of high fat induced body weight gain, white fat (i.e., epididymal, visceral and peritoneal fat) development, adipocyte hypertrophy and the development of hyperinsulinemia and hyperliptinemia. Serum triglyceride and total cholesterol level was greatly reduced by hangihyung garlic supplementation (p<0.05). The HDL-cholesterol level was increased by dietary hangihyung and nangihyung garlic. There were slight non-significant decreases in triglyceride and total cholesterol of HF+N group as compared to those of HF group. Leptin level of HF+H group was found to be significantly lower than HF group (p<0.05). There was no significant difference among N group and HF+N group. These results suggest that hangihyung garlic may lead to the higher activity in improving lipid profiles than nangihyung garlic. Whether the hypolipidemic effect of garlic increases in a species-dependent has yet to be determined and awaits further research.