채용시 건강진단 폐지 후 배치전 건강진단의 실태

서춘희,이종태,김대환,손병철,이창희,김휘동,안진동 大韓産業醫學會 2008 대한직업환경의학회지 Vol.20 No.3

목적: 산업안전보건법 개정 후 배치전 건강진단의 실시 현황 및 보건관리자의 인식도를 파악하고자 하였다. 방법: 부산과 경남에 위치하는 특수건강진단기관 2개소 에서 2006년 1월 1일에서 2006년 12월 31일까지 배치전 건강진단을 받은 근로자 6,507명을 대상으로 배치전 건 강진단서 판정결과를 검토하였다. 건강관리구분 유소견자 판정을 받은 근로자 330명을 대상으로 전화인터뷰를 시도하여 성공한 185명을 최종 연구 대상으로 하였다. 그리고 동 기관에서 관리하고 있으며 특수건강진단을 실시하는 보건관리대행 사업장 중에서 169개의 사업장 보건 관리자를 대상으로 2007년 5월 1일에서 9월 30일까지 설문조사를 하였다. 결과: 근로자 전화 인터뷰 조사에서 배치전 건강진단 결과 질환 유소견 판정때문에 채용이 거부된 사람은 51명 (27.4%)이었다. 보건관리자를 대상으로 한 설문조사에서 채용시 건강진단의 폐지를 모르는 사업장이 39개(23.1%)였다. 배치전 건강진단을 근로자 채용결정 후 부서배치 전에 실시하는 사업장 73개(43.2%)중에서 그 결과를 부서배치에 활용한다고 응답한 사업장이 63개 (37.3%)였다 질환유소견 판정을 받았을 때 고혈압,당뇨병,고지혈증 등 만성 칠환이 있는 경우 각각 20개(11.8%),21개(12.4%),22개(13.0%) 사업장에서 근로자를 고용하지 않는다고 답했고,업무상 질병과 관련된 청력이상,요추부 방사선 이상소견이 있을 때 각각 76개 (44.4%),75개(43.8%) 사업장에서 근로자를 고용하지 않는다고 답했다. 결론: 채용전 건강진단이 폐지되고 배치전 건강진단에 대한 법 조항이 개정되었음에도 불구하고 사업장에서는 법규에 대한 이해가 불충분하여 여전히 배치전 건강진단이 취업시 불건강자를 가려내는 목적으로 이용되고 있으며,업무 적합성 개념에 대한 이해가 불충분하였다. 따라서 사업주는 배치전 건강진단 실시시기를 준수하고 건강 진단 기관에 배치 예정 업무에 대해 구체적인 정보를 제공하여야 한다. 정부에서는 법규 개정 후 홍보에 힘쓰고,법규 시행 후 적절한 정책 평가도 병행하여야 한다. Objectives: We investigated the status of the preplacement medical examination after the revision of the industrial safety and health law on Oct. 7, 2005 by the Ministry of Labor. Methods: Preplacement medical certificates of 6,507 recruits issued by two hospitals in Busan, Kyeongnam Province from Jan. 1 to Dec. 31,2006 were reviewed. Telephone interviews were performed to the recruits with disease and self-reported questionnaires were administrated to health and safety personnel from May 1 to Sep. 30, 2007. Results: Interviews were conducted with 185(56.1 %) recruits with disease, 51(27.4%) of whom were rejected for employment due to the preplacement medical certificate. The questionnaire survey for the health and safety personnel revealed that 39(22.9%) personnel were unaware of the annulment of the preemployment medical examination. Eighty(48.8%) of the health and safety personnel answered that they performed a preplacement medical examination after employment, and 63(37.3%) made a practical application of the workers' placement. The recruits with chronic conditions were refused employment: 20 (11.8%) due to hypertension, 21 (12.4%) diabetes mellitus and 22(13.0%) hyperlipidemia. The recruits with work-related diseases were also refused employments: 76(44.4%) due to lumbar spine abnormality and 75(43.8%) hearing loss. Conclusions: Despite the annulment of the pre-employment medical examination, a preplacement medical examination was often used to discriminate among healthy and diseased recruits. Employers must respect the law for the point of time of the preplacement medical examination and the payment of cost. The government should publicize the revision of the objectives of the law. We suggest that health professionals elucidate the job fitness through the development of the assessment tools and maintain the confidentiality of recruits.

대심도 연약지반에 근입된 PHC말뚝기초의 형태별 관입성 분석

손창희(Chang-Hui Son),최영수(Young-Soo Choi),김명학(Myung-Hak Kim) 한국지반환경공학회 2006 한국지반환경공학회 학술발표회논문집 Vol.2006 No.-

서평 : 서울대학교 노동법연구회편, 『노동법연구』

손창희 ( Son Chang Hui ) 서울대학교 법학연구소 1992 서울대학교 法學 Vol.33 No.2

Sauchinone, a lignan from Saururus chinensis, attenuates neutrophil pro-inflammatory activity and acute lung injury

( Hui Jing Han ),( Mei Li ),( Jong Keun Son ),( Chang Seob Seo ),( Seung Won Song ),( Sang Hyun Kwak ),( Hong Beom Bae ) 영남대학교 약품개발연구소 2014 영남대학교 약품개발연구소 연구업적집 Vol.24 No.0

Previous studies have shown that sauchinone modulates the expression of inflammatory mediators through mitogen-activated protein kinase (MAPK) pathways in various cell types. However, little information exists about the effect of sauchinone on neutrophils, which play a crucial role in inflammatory process such as acute lung injury (ALI). We found that sauchinone decreased the phosphorylation of p38 MAPK in lipopolysaccharide (LPS)-stimulated murine bone marrow neutrophils, but not ERK1/2 and JNK. Exposure of LPS-stimulated neutrophils to sauchinone or SB203580, a p38 inhibitor, diminished production of tumor necrosis factor (TNF)-α and macrophage inflammatory protein (MIP)-2 compared to neutrophils cultured with LPS. Treatment with sauchinone decreased the level of phosphorylated ribosomal protein S6 (rpS6) in LPS-stimulated neutrophils. Systemic administration of sauchinone to mice led to reduced levels of phosphorylation of p38 and rpS6 in mice lungs given LPS, decreased TNF-α and MIP-2 production in bronchoalveolar lavage fluid, and also diminished the severity of LPS-induced lung injury, as determined by reduced neutrophil accumulation in the lungs, wet/dry weight ratio, and histological analysis. These results suggest that sauchinone diminishes LPS-induced neutrophil activation and ALI.

Sauchinone, a lignan from Saururus chinensis, attenuates neutrophil pro-inflammatory activity and acute lung injury

( Hui Jing Han ),( Mei Li ),( Jong Keun Son ),( Chang Seob Seo ),( Seung Won Song ),( Sang Hyun Kwak ),( Hong Beom Bae ) 영남대학교 약품개발연구소 2013 영남대학교 약품개발연구소 연구업적집 Vol.23 No.0

Previous studies have shown that sauchinone modulates the expression of inflammatory mediators through mitogen-activated protein kinase (MAPK) pathways in various cell types. However, little information exists about the effect of sauchinone on neutrophils, which play a crucial role in inflammatory process such as acute lung injury (ALI). We found that sauchinone decreased the phosphorylation of p38 MAPK in lipopolysaccharide (LPS)-stimulated murine bone marrow neutrophils, but not ERK1/2 and JNK. Exposure of LPS-stimulated neutrophils to sauchinone or SB203580, a p38 inhibitor, diminished production of tumor necrosis factor (TNF)-α and macrophage inflammatory protein (MIP)-2 compared to neutrophils cultured with LPS. Treatment with sauchinone decreased the level of phosphorylated ribosomal protein S6 (rpS6) in LPS-stimulated neutrophils. Systemic administration ofsauchinone to mice led to reduced levels of phosphorylation of p38 and rpS6 in mice lungs given LPS, decreased TNF-α and MIP-2 production in bronchoalveolar lavage fluid, and also diminished the severity of LPS-induced lung injury, as determined by reduced neutrophil accumulation in the lungs, wet/dry weight ratio, and histological analysis. These results suggest that sauchinone diminishes LPS-induced neutrophil activation and ALI. ⓒ2013 Elsevier B.B.All rights reserved.

Evaporation Heat Transfer Characteristics of $CO_2$ in a Horizontal Tube

Son Chang-Hyo,Kim Dae-Hui,Choi Sun-Muk,Kim Young-Ryul,Oh Hoo-Kyu The Society of Air-Conditioning and Refrigerating 2005 International Journal of Air-Conditioning and Refr Vol.13 No.4

The evaporation heat transfer coefficient of $CO_2$ (R-744) in a horizontal tube was investigated experimentally. The experiments were conducted without oil in a closed refrigerant loop which was driven by a magnetic gear pump. The main components of the refrigerant loop are a receiver, a variable-speed pump, a mass flow meter, a pre-heater and evaporator (test section). The test section consists of a smooth horizontal stainless steel tube of 7.75 mm inner diameter. The experiments were conducted at mass flux of 200 to $500kg/m^2s$, saturation temperature of $-5^{\circ}C\;to\;5^{\circ}C$, and heat flux of 10 to $40kW/m^2$. The test results showed the evaporation heat transfer of $CO_2$ has greater effect on nucleate boiling than convective boiling. The evaporation heat transfer coefficient of $CO_2$ is highly dependent on the vapor quality, heat flux and saturation temperature. The evaporation heat transfer coefficient of $CO_2$ is very larger than that of R-22 and R-134a. In comparison with test results and existing correlations, the best fit of the present experimental data is obtained with the correlation of Jung et al. But the existing correlations failed to predict the evaporation heat transfer coefficient of $CO_2$. Therefore, it is necessary to develop reliable and accurate predictions determining the evaporation heat transfer coefficient of $CO_2$ in a horizontal tube.

Evaporation Heat Transfer Characteristics of CO₂ in a Horizontal Tube

Chang-Hyo Son,Dae-Hui Kim,Sun-Muk Choi,Young-Ryul Kim,Hoo-Kyu Oh 대한설비공학회 2005 International Journal Of Air-Conditioning and Refr Vol.13 No.4

The evaporation heat transfer coefficient of CO₂ (R-744) in a horizontal tube was investigated experimentally. The experiments were conducted without oil in a closed refrigerant loop which was driven by a magnetic gear pump. The main components of the refrigerant loop are a receiver, a variable-speed pump, a mass flow meter, a pre-heater and evaporator(test section). The test section consists of a smooth horizontal stainless steel tube of 7.75 ㎜ inner diameter. The experiments were conducted at mass flux of 200 to 500 ㎏/㎡s, saturation temperature of -5℃ to 5℃, and heat flux of 10 to 40 ㎾/㎡. The test results showed the evaporation heat transfer of CO₂ has greater effect on nucleate boiling than convective boiling. The evaporation heat transfer coefficient of CO₂ is highly dependent on the vapor quality, heat flux and saturation temperature. The evaporation heat transfer coefficient of CO₂ is very larger than that of R-22 and R-134a. In comparison with test results and existing correlations, the best fit of the present experimental data is obtained with the correlation of Jung et al. But the existing correlations failed to predict the evaporation heat transfer coefficient of CO₂. Therefore, it is necessary to develop reliable and accurate predictions determining the evaporation heat transfer coefficient of CO₂ in a horizontal tube.

Screening of Natural Compounds Stimulating ADH Using Natural Products Libraries

Chang Hee Lee,Jong Hwa Kim,Ki Yu Kim,Mi Hui Son,Kyung Sook Im,Eun Jung Ku,Kwang Hee Park,Mi Hye Yoon 한국식품영양과학회 2016 한국식품영양과학회 학술대회발표집 Vol.2016 No.10

Diastereoisomer- and species-specific distribution of hexabromocyclododecane (HBCD) in fish and marine invertebrates

Son, Min-Hui,Kim, Jongchul,Shin, Eun-Su,Seo, Sung-hee,Chang, Yoon-Seok Elsevier 2015 Journal of hazardous materials Vol.300 No.-

<P><B>Abstract</B></P> <P>The levels and distributional characteristics of hexabromocyclododecane (HBCD) diastereoisomers have been largely reported for various fish and select shellfish. In this study, we reclassified a number and variety of marine invertebrates, including shellfish, to further contribute to the comprehensive understanding of the effects and assessment of human exposure to HBCD. Overall, 30 marine invertebrate species (<I>n</I> =188) were investigated and the following order of ∑<SUB>2</SUB>HBCD (α- and γ-HBCD) was observed: fish>chordata>cephalopoda>echinodermata>bivalve>crustacea. The marine invertebrates that were reclassified into nektonic and benthic organisms showed similar concentration of ∑<SUB>2</SUB>HBCD. The feeding habits and modes of the marine organisms were considered to compare the degree of bioaccumulation and diastereoisomer-specific distribution of HBCD due to the effects of the environment in and around pollution sources, as well as the organisms’ metabolic capacities. To the best of our knowledge, this is the first study to examine the species-specific distribution patterns of HBCD for both fish and marine invertebrates. We expect to significantly expand the understanding of the environmental fate of HBCD for marine organisms.</P> <P><B>Highlights</B></P> <P> <UL> <LI> This study shows the levels of HBCD diastereoisomers in fish and marine invertebrates. </LI> <LI> Fish and marine invertebrates with different metabolic capacities may affect the distribution patterns of HBCD diastereoisomers. </LI> <LI> α-HBCD was the dominant diastereoisomer in almost all species. </LI> <LI> There are no significant differences in levels of ∑<SUB>2</SUB>HBCD between nektonic and benthic organisms. </LI> <LI> Feeding habits and feeding modes of marine organisms also have a similar effect on the diastereoisomeric fraction of α-HBCD. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet induced obese mice

Hui Jung Son,Min-Ju Seo,Soon Ju Park,A Reum Lee,Seo-Hyuk Chang,Kye Won Park 한국식품영양과학회 2018 한국식품영양과학회 학술대회발표집 Vol.2018 No.10