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Smyth, S.R.,Bailey, W.G.,Skretkowiez, A.L. The Korean Society of Ginseng 1988 Journal of Ginseng Research Vol.12 No.2
Correlations between various morphological characteristics of Panax quinquefolium plants grown in Lytton, British Columbia, Canada were assessed for 1-through 4-year old plants. Root dry weight, the dependent variable, was found to be strongly related to leaf dry weight, leaf length and root length for 1-and 2-year old plants during the middle of the growing season. For 1- and 2-year old plants at the end of the growing season, root dry weight was found to be related to leaf dry weight, leaf length and stem dry weight. For 3 and 4-year old plants, root dry weight was found to be related to leaf dry weight, leaf length and stem dry weight. For 3- and 4-year old plants, root dry weight was found to be related to leaf dry weight. For practical considerations, this latter relationship provides a simple method for selecting superior plants from which seed can be harvested.
The Neuroimmunology of Schizophrenia
Annya M. Smyth,Stephen M. Lawrie 대한정신약물학회 2013 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.11 No.3
Schizophrenia (SCZ) is a polygenic, multi-factorial disorder and a definitive understanding of its pathophysiology has been lacking since it was first described more than a century ago. The predominant pharmacological approach used to treat SCZ is the use of dopamine receptor antagonists. The fact that many patients remain symptomatic, despite complying with medication regimens,emphasises the need for a more encompassing explanation for both the causes and treatment of SCZ. Recent neuroanatomical,neurobiological, environmental and genetic studies have revived the idea that inflammatory pathways are involved in the pathogenesis of SCZ. These new insights have emerged from multiple lines of evidence, including the levels of inflammatory proteins in the central nervous system (CNS) of patients with SCZ and animal models. This review focuses on aberrant inflammatory mechanisms present both before and during the onset of the psychotic symptoms that characterise SCZ and discusses recent research into adjunctive immune system modulating therapies for its more effective treatment.
Sarah Louise Smyth,Hooman Soleymani Majd 대한산부인과학회 2023 Obstetrics & Gynecology Science Vol.66 No.5
Objective We present an educational technique for the safe completion of complete cytoreduction of diaphragmatic disease for the management of advanced ovarian malignancy. Methods We demonstrated these steps with attention to anatomical landmarks and surgical approaches, considering intraoperative and postoperative morbidity and mortality. Results We present the case of a 49-year-old female patient diagnosed with suspected stage 3C ovarian malignancy following diagnostic laparoscopy. We demonstrate the surgical application of the Pringle manoeuvre, type 3 liver mobilisation, and full-thickness diaphragmatic resection. This was completed with a primary closure technique, with integrity ensured through the performance of an air test and Valsalva manoeuvre. Final histology confirmed a serous borderline tumour with invasive implants within a port site nodule (stage 4A). Conclusion This technique affirms the essential skills in gynaecological oncology training and details a challenging case requiring advanced surgical skills and knowledge, with specific consideration for intraoperative multidisciplinary decision-making.
Extraction and characterization of a novel Terminalia pectin
Chaliha, Mridusmita,Williams, David,Smyth, Heather,Sultanbawa, Yasmina 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.1
This study reports the investigation into pectin present in Terminalia ferdinandiana-a native Australian fruit utilised in dietary supplement industry. Citric acid extraction was carried out to extract pectin from two commercially available T. ferdinandiana products-frozen puree and freeze-dried puree powder. The yields of the extracted pectin were measured at various pHs (2.0, 3.0 and 4.0) and times (30, 60 and 120 min) at $75^{\circ}C$. Pectin yield ranged between 4.8 and 21%. Freeze-dried powder had a higher pectin yield compared to puree. Extraction at pH 3 for 120 min resulted in the highest yield from both puree (15%) and powder (21%). T. ferdinandiana pectins were found to have low methoxyl content with degree of esterification of 35.07 and 34.74% for puree and powder, respectively. Fourier transform infrared spectroscopy confirmed that the extracts were pectin.
THE ROLE OF CONFUCIAN VALUES IN EAST ASIAN DEVELOPMENT : BEFORE AND AFTER THE FINANCIAL CRISIS
Wang, Jin-guo,Russell Smyth,Hwee, Tan-Dai 서울대학교 국제지역원 2000 Journal of International and Area Studies Vol.7 No.1
Asian Values provided a convincing cultural explanation for high economic growth in East Asia up until the recent economic crisis, without many of the social problems that are normally associated with rapid development, However, the Asian economic crisis has prompted a re-examination of Asian values. This paper argues that the positive aspects of Confucian values outweigh its minuses and that it is up to the East Asian economies to take steps to maximize its positive aspects, The paper also argues that its minuses and that it is up East Asian economies to take steps to maximize its positive aspects, The paper also argues that its Weakness cannot be entirely blamed for the Asian economic crisis and that given the overwhelming evidence of East Asia's remarkable economic performance over a sustained period, the effects of Confucianism on economic development should not be overlooked.
Extraction and characterization of a novel Terminalia pectin
Mridusmita Chaliha,David Williams,Heather Smyth,Yasmina Sultanbawa 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.1
This study reports the investigation into pectin present in Terminalia ferdinandiana—a native Australian fruit utilised in dietary supplement industry. Citric acid extraction was carried out to extract pectin from two commercially available T. ferdinandiana products—frozen puree and freeze-dried puree powder. The yields of the extracted pectin were measured at various pHs (2.0, 3.0 and 4.0) and times (30, 60 and 120 min) at 75 C. Pectin yield ranged between 4.8 and 21%. Freeze-dried powder had a higher pectin yield compared to puree. Extraction at pH 3 for 120 min resulted in the highest yield from both puree (15%) and powder (21%). T. ferdinandiana pectins were found to have low methoxyl content with degree of esterification of 35.07 and 34.74% for puree and powder, respectively. Fourier transform infrared spectroscopy confirmed that the extracts were pectin.
Matthew J. Herpin,Hugh D. C. Smyth 한국약제학회 2018 Journal of Pharmaceutical Investigation Vol.48 No.1
Super-heated aqueous particle engineering (SHAPE) is a novel particle engineering technology that utilizes the elevated boiling point of pressurized water in order to melt and emulsify hydrophobic drug particles, and then use the newly formed droplets as templates for engineering new particles with different physicochemical properties. When the temperature of an aqueous phase is elevated above the melting point of a drug, the drug quickly melts and forms a low viscosity, immiscible liquid, which is then broken up into nano or micro sized droplets under continuous stirring. The interfacial tension between the droplets and liquid serves to shape them into uniform spherical particles. These droplets can hold their shape as the dispersion is cooled back down below the melting point of the drug. During this cooling stage, either solid crystalline or amorphous microparticles can be formed depending on the cooling rate that is selected. The particles are then collected and can be utilized in many different pharmaceutical applications. In this manuscript, we use this particle engineering technique, employing the model drug carvedilol (CARV), to investigate the effect that different stabilizers/surfactants exert on the particle size and morphology.