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      • KCI등재

        Band gap opening in zigzag graphene nanoribbon modulated with magnetic atoms

        Shi-Hua Tan,Li-Ming Tang,Ke-Qiu Chen 한국물리학회 2014 Current Applied Physics Vol.14 No.11

        The effects of magnetic atom on the band structure of zigzag-edged graphene nanoribbons are investigated by the density functional theory. The results show that for narrow zigzag-edged graphene nanoribbons, the band gap can be opened duo to the spin-up/spin-down charges being re-enriched on the edge sites. However, for the wide zigzag-edged graphene nanoribbons, a spin-up/spin-down halfmetallic property can be observed. Moreover, it is found that the Seebeck coefficients in the narrow zigzag-edged graphene nanoribbons are reversed and enlarged, which provides a way to design novel thermoelectric device.

      • SCOPUSKCI등재

        Managing the Indirect Effects of Environmental Regulation and Performance Measurement

        Tan, Kim Hua,Shi, Lei,Tseng, M.L.,Cui, Wen-Jie Korean Institute of Industrial Engineers 2014 Industrial Engineeering & Management Systems Vol.13 No.2

        Sustainable development has always been the top agenda of many governments. Especially, the concept of 'Ecological Civilisation (EC)' is gaining substantial attention from China's new leaders. However, regional government officers may manipulate or change top level policy in order to suit their own interests or if they are unable to meet the varied pressures of achieving the set measures. Thus, policy makers can unwittingly cause a negative or positive impact on the firms or regional development through the implementation of EC regulations and the requirement to measure, monitor and report performance measurement (PM) information. This can potentially have significant consequences for the firms, the industry sector, and China as a whole. The aim of this research is to explore and evaluate previous work focusing on the relationship and links between regulation and PM. This research will make a significant knowledge contribution to the emerging and yet important area in EC related research. A good understanding of the linkages between PM and EC will assist policy makers to better formulate suitable regulatory control mechanisms at the field level. Moreover, they may take the PM and EC linkages into consideration when setting policy frameworks by minimizing the negative effects and take advantages of the positive consequences.

      • SCISCIESCOPUS

        The MALATANG Survey: The <i>L</i><sub>GAS</sub>-<i>L</i><sub>IR</sub> Correlation on Sub-kiloparsec Scale in Six Nearby Star-forming Galaxies as Traced by HCN <i>J</i> = 4 → 3 and HCO<sup>+</sup><i>J</i> = 4 → 3

        Tan, Qing-Hua,Gao, Yu,Zhang, Zhi-Yu,Greve, Thomas R.,Jiang, Xue-Jian,Wilson, Christine D.,Yang, Chen-Tao,Bemis, Ashley,Chung, Aeree,Matsushita, Satoki,Shi, Yong,Ao, Yi-Ping,Brinks, Elias,Currie, Malco American Astronomical Society 2018 The Astrophysical journal Vol.860 No.2

        <P>We present HCN J = 4 -> 3 and HCO+ J = 4 -> 3 maps of six nearby star-forming galaxies, NGC 253, NGC 1068, IC 342, M82, M83, and NGC 6946, obtained with the James Clerk Maxwell Telescope as part of the MALATANG survey. All galaxies were mapped in the central 2' x 2' region at 14 '' (FWHM) resolution (corresponding to linear scales of similar to 0.2-1.0 kpc). The L-IR-L'(dense) relation, where the dense gas is traced by the HCN J = 4 -> 3 and the HCO+ J = 4 -> 3 emission, measured in our sample of spatially resolved galaxies is found to follow the linear correlation established globally in galaxies within the scatter. We find that the luminosity ratio, L-IR/L'(dense), shows systematic variations with L-IR within individual spatially resolved galaxies, whereas the galaxy-integrated ratios vary little. A rising trend is also found between L-IR/L'(dense) ratio and the warm-dust temperature gauged by the 70 mu m/100 mu m flux ratio. We find that the luminosity ratios of IR/HCN (4-3) and IR/HCO+ (4-3), which can be taken as a proxy for the star formation efficiency (SFE) in the dense molecular gas (SFEdense), appear to be nearly independent of the dense gas fraction (f(dense)) for our sample of galaxies. The SFE of the total molecular gas (SFEmol) is found to increase substantially with f(dense) when combining our data with those on local (ultra) luminous infrared galaxies and high-z quasars. The mean L'(HCN(4-3))/L'(HCO+(4-3)) line ratio measured for the six targeted galaxies is 0.9 +/- 0.6. No significant correlation is found for the L'(HCN(4-3)) L'(HCO+(4-3)) ratio with the star formation rate as traced by L-IR, nor with the warm-dust temperature, for the different populations of galaxies.</P>

      • KCI등재

        Managing the Indirect Effects of Environmental Regulation and Performance Measurement

        Kim Hua Tan,Lei Shi,M. L. Tseng,Wen-Jie Cui 대한산업공학회 2014 Industrial Engineeering & Management Systems Vol.13 No.2

        Sustainable development has always been the top agenda of many governments. Especially, the concept of ‘Ecological Civilisation (EC)’ is gaining substantial attention from China’s new leaders. However, regional government officers may manipulate or change top level policy in order to suit their own interests or if they are unable to meet the varied pressures of achieving the set measures. Thus, policy makers can unwittingly cause a negative or positive impact on the firms or regional development through the implementation of EC regulations and the requirement to measure, monitor and report performance measurement (PM) information. This can potentially have significant consequences for the firms, the industry sector, and China as a whole. The aim of this research is to explore and evaluate previous work focusing on the relationship and links between regulation and PM. This research will make a significant knowledge contribution to the emerging and yet important area in EC related research. A good understanding of the linkages between PM and EC will assist policy makers to better formulate suitable regulatory control mechanisms at the field level. Moreover, they may take the PM and EC linkages into consideration when setting policy frameworks by minimizing the negative effects and take advantages of the positive consequences.

      • <i>Dendrobiumnaungmungense</i> ( Orchidaceae , Dendrobieae ), a new species from Kachin State, Myanmar

        Liu, Qiang,Zhou, Shi-Shun,Jin, Xiao-Hua,Pan, Bo,Maung, Kyaw Win,Zyaw, Myint,Li, Ren,Quan, Rui-Chang,Tan, Yun-Hong Pensoft Publishers 2018 PhytoKeys Vol.94 No.-

        <P>Abstract</P><P><I>Dendrobiumnaungmungense</I>, a new species from Naungmung, Kachin State, North Myanmar, is described and illustrated. It is morphologically similar to <I>D.ciliatilabellum</I> and <I>D.vexabile</I>, but the epichile is oblong with three long-ciliate laminae and the column wing has significant denticulation. A preliminary risk-of-extinction assessment shows that the new species should be regarded as Critically Endangered (CR) according to the IUCN Red List Categories and Criteria.</P>

      • KCI등재

        New Safrole Oxide Derivatives: Synthesis and in vitro Antiproliferative Activities on A549 Human Lung Cancer Cells

        Li-Ying Wang,Xiu-Hua Wang,Jia-Lian Tan,Shuai Xia,Heng-Zhi Sun,Jin-Wen Shi,Ming-Dong Jiang,Liang Fang,Hua Zuo,Gautam Dupati,장기완,신동수 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.11

        A number of novel small molecules, safrole oxide derivatives 4a-c, 6a-c, 9a-h, were synthesized by the reaction of safrole oxide with anilines 3 and 5, or its alkyl allyl ether derivative 7 with alkyl bromide 8 in moderate yields. The antiproliferative effects of all the target molecules on A549 cell growth were investigated and it was found that the 14 novel compounds could suppress A549 lung cancer cell growth. Among them, compound 6b was the most effective compound in inhibiting the proliferation of A549 cells.

      • SCOPUSKCI등재

        New Safrole Oxide Derivatives: Synthesis and in vitro Antiproliferative Activities on A549 Human Lung Cancer Cells

        Wang, Li-Ying,Wang, Xiu-Hua,Tan, Jia-Lian,Xia, Shuai,Sun, Heng-Zhi,Shi, Jin-Wen,Jiang, Ming-Dong,Fang, Liang,Zuo, Hua,Dupati, Gautam,Jang, Kiwan,Shin, Dong-Soo Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.11

        A number of novel small molecules, safrole oxide derivatives 4a-c, 6a-c, 9a-h, were synthesized by the reaction of safrole oxide with anilines 3 and 5, or its alkyl allyl ether derivative 7 with alkyl bromide 8 in moderate yields. The antiproliferative effects of all the target molecules on A549 cell growth were investigated and it was found that the 14 novel compounds could suppress A549 lung cancer cell growth. Among them, compound 6b was the most effective compound in inhibiting the proliferation of A549 cells.

      • KCI등재

        Selection of the Lowest Instrumented Vertebra and Relative Odds Ratio of Distal Adding-on for Lenke Type 1A and 2A Curves in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis

        Che-Wei Liu,Lawrence G. Lenke,Lee A. Tan,Taemin Oh,Kou-Hua Chao,Shi-Ding Lin,Ru-Yu Pan 대한척추신경외과학회 2020 Neurospine Vol.17 No.4

        Objective: To examine existing literature and pool the data to determine the relative odds ratio of “adding-on” (AO) based on various reported criteria for lower instrumented vertebra (LIV) selection in Lenke type 1A and 2A curves. Methods: Using electronic databases, studies reporting on AO and LIV selection in Lenke type 1A and 2A curves were identified. Studies were excluded if they failed to meet the following criteria: ≥30 patients, Lenke type 1A or 2A curves, thoracic-only fusions, and inclusion of outcome differences in AO and non-AO groups. Review articles, letters, and case reports were excluded. Results: Six studies were identified reporting on 732 patients with either Lenke type 1A or 2A curves treated with thoracic-only fusions. Five different landmarks were used for LIV selection in these studies including the stable vertebra (SV) -1, end vertebra (EV) +1, neutral vertebra (NV), touched vertebra (TV), and substantially touched vertebra (STV) versus nonsubstantially touched vertebra (nSTV) +1. The pooled odds ratios of AO for choosing LIV at levels above the afore landmarks (i.e., ending the construct “short”) versus at the landmarks were 2.59 (SV-1), 2.43 (EV+1), 3.05 (NV), 3.40 (TV), and 4.52 (STV/nSTV+1), all at 95% confidence interval. Conclusion: Five landmarks shared a similar characteristic in that the incidence of AO was significantly higher if the LIV was proximal to the chosen landmark. In addition, choosing STV/(nSTV+1) as the LIV have the lowest absolute risk of AO and the greatest risk reduction. If additional levels were fused (i.e., LIV distal to the landmark), there was no statistically significant benefit in further reducing the risk of AO. Selection of the optimal LIV is a complex issue and spine surgeons must balance the risk of AO with the need for motion preservation in young patients.

      • Intervention Effects of Nedaplatin and Cisplatin on Proliferation and Apoptosis of Human Tumour Cells in Vitro

        Su, Xiang-Yu,Yin, Hai-Tao,Li, Su-Yi,Huang, Xin-En,Tan, Hua-Yang,Dai, Hong-Yu,Shi, Fang-Fang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

        Objective: To study synergistic effects of nedaplatin and cisplatin on three human carcinoma cell lines (esophageal carcinoma cell line Eca-109, ovarian carcinoma Skov-3 and cervical carcinoma Hela). Methods: Inhibition effects were evaluated by MTT assay and cell apoptosis was detected by flow cytometry. In addition, changes of Ki-67, Bax and Bcl-2 at mRNA and protein levels were quantified by RT-PCR and Western blotting. Results: Growth inhibition in each cell lines was dose-dependent after exposure to nedaplatin or cisplatin alone. The interaction of the two drugs was synergistic at higher concentrations according to the median-effect principle. The inhibition rates with nedaplatin, cisplatin and combined treatment were $41.9{\pm}4.1%$, $47.4{\pm}2.9%$, $52.5{\pm}0.9%$(Eca-109), $39.0{\pm}1.26%$, $45.0{\pm}1.45%$, $56.2{\pm}1.44%$ (Skov-3) and $44.8{\pm}2.11%$, $46.9{\pm}0.99%$, $56.6{\pm}1.83%$ (Hela) respectively, with increase in apoptosis. Compared with the nedaplatin or cisplatin alone treatment group, the combinative treatment group's Ki-67 and bcl-2 mRNA (protein) expression was decreased while that of Bax mRNA (protein) was increased. Conclusion: Compared to the effects of nedaplatin or cisplatin alone at high concentrations, combination of nedaplatin and cisplatin at low concentrations proved to be much more effective for inhibition of proliferation and the induction of apoptosis in the Eca-109, Skov-3 and Hela cell lines.

      • SCIESCOPUSKCI등재

        Effects of a traditional Chinese medicine formula and its extraction on muscle fiber characteristics in finishing pigs, porcine cell proliferation and isoforms of myosin heavy chain gene expression in myocytes

        Yu, Qin Ping,Feng, Ding Yuan,He, Xiao Jun,Wu, Fan,Xia, Min Hao,Dong, Tao,Liu, Yi Hua,Tan, Hui Ze,Zou, Shi Geng,Zheng, Tao,Ou, Xian Hua,Zuo, Jian Jun Asian Australasian Association of Animal Productio 2017 Animal Bioscience Vol.30 No.11

        Objective: This study evaluated the effects of a traditional Chinese medicine formula (TCMF) on muscle fiber characteristics in finishing pigs and the effects of the formula's extract (distilled water, ethyl acetate and petroleum ether extraction) on porcine cell proliferation and isoforms of myosin heavy chain (MyHC) gene expression in myocytes. Methods: In a completely randomized design, ninety pigs were assigned to three diets with five replications per treatment and six pigs per pen. The diets included the basal diet (control group), TCMF1 (basal diet+2.5 g/kg TCMF) and TCMF2 (basal diet+5 g/kg TCMF). The psoas major muscle was obtained from pigs at the end of the experiment. Muscle fiber characteristics in the psoas major muscle were analyzed using myosin ATPase staining. Cell proliferation was measured using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) dye and cytometry. Isoforms of MyHC gene expression were detected by real-time quantitative polymerase chain reaction. Results: The final body weight and carcass weight of finishing pigs were increased by TCMF1 (p<0.05), while the psoas major muscle cross-sectional area was increased by TCMF (p<0.05). The cross-sectional area and diameter of psoas major muscle fiber Ι, IIA, and IIB were increased by TCMF2 (p<0.05). The cross-sectional area and fiber diameter of psoas major muscle fiber IIA and IIB were increased by diet supplementation with TCMF1 (p<0.05). Psoas major muscle fiber IIA and IIB fiber density from the pigs fed the TCMF1 diet and the type IIB fiber density from the pigs fed the TCMF2 diet were lower compared to pigs fed the control diet (p<0.05). Pigs fed TCMF2 had a higher composition of type Ι fiber and a lower percentage of type IIB fiber in the psoas major muscle (p<0.05). The expression levels of MyHC Ι, MyHC IIa, and MyHC IIx mRNA increased and the amount of MyHC IIb mRNA decreased in the psoas major muscle from TCMF2, whereas MyHC Ι and MyHC IIx mRNA increased in the psoas major muscle from TCMF1 (p<0.05). Peroxisome proliferator-activated receptor ${\gamma}$ $coactivator-1{\alpha}$ and CaN mRNA expression in the psoas major muscle were up-regulated by TCMF (p<0.05). Porcine skeletal muscle satellite cell proliferation was promoted by $4{\mu}g/mL$ and $20{\mu}g/mL$ TCMF water extraction (p<0.05). Both $1{\mu}g/mL$ and $5{\mu}g/mL$ of TCMF water extraction increased MyHC IIa, MyHC IIb, and MyHC IIx mRNA expression in porcine myocytes (p<0.05), while MyHC Ι mRNA expression in porcine myocytes was decreased by $5{\mu}g/mL$ TCMF water extraction (p<0.05). Porcine myocyte MyHC Ι and MyHC IIx mRNA expression were increased, and MyHC IIa and MyHC IIb mRNA expression were down-regulated by $5{\mu}g/mL$ TCMF ethyl acetate extraction (p<0.05). MyHC Ι and MyHC IIa mRNA expression in porcine myocytes were increased, and the MyHC IIb mRNA expression was decreased by $1{\mu}g/mL$ TCMF ethyl acetate extraction (p<0.05). Four isoforms of MyHC mRNA expression in porcine myocytes were reduced by $5{\mu}g/mL$ TCMF petroleum ether extraction (p<0.05). MyHC IIa mRNA expression in porcine myocytes increased and MyHC IIb mRNA expression decreased by $1{\mu}g/mL$ in a TCMF petroleum ether extraction (p<0.05). Conclusion: These results indicated that TCMF amplified the psoas major muscle cross-sectional area through changing muscle fiber characteristics in finishing pigs. This effect was confirmed as TCMF extraction promoted porcine cell proliferation and affected isoforms of MyHC gene expression in myocytes.

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