米麥混食이 Cholesterol 및 無機質代射에 미치는 影響

姜信英,孫延瑗,柳總根 고려대학교 의과대학 1986 고려대 의대 잡지 Vol.23 No.1

This study was devised to investigate the effect of dietary fiber of barley on cholesterol metabolism and absorption of mineral on feeding either rice diets or barley mixed diets. Wistar albino rats were administered starch, rice, rice containing balrey by 10%, 30%, and 60% and barley diets for 2, 4, and 6 weeks. 1. Serum cholesterol level was higher in the rice diet group than in the barley diet group. In the meantime, fecal steroid content was highest in the barley diet group and decreased as the proportion of barley in diets became lower. 2. Correlation coefficient between the increase of fecal n-eight and the increase of fecal steroid content was 0. 988(p<0. 001). 3. Fecal Fe and Ca content was net affected by the extent of barley and rice in diets. But fecal Ka and K content was high in the barley diet group. 4. Fecal weight and fecal moisture content was highest in the barley diet group, and became lower in the diet group where barley was added in smaller proportion. The increase of fecal weight was significantly related with the increase of fecal water content(r=0.918, p<0.001). 5. Serum lipid level was lower in the diet group containing more barley than in the rice diet group. In contrast, focal lipid content was highest in the barley diet group, and decreased in proportion to the decrease of barley addition in diets. 6. Accumulation of adipose tissue was observed In the rice diet group, 2nd the more barley mixed in diets, the lower it was. 7. Length of small intestine was longer in the barley diet group than in the rice diet group.

成熟赤血球의 Evans´blue 吸收에 미치는 二價金屬이온의 影響에 關한 硏究

姜信英,曺龍鎬 慶熙大學校 1984 論文集 Vol.13 No.-

Non-nucleated mature erythrocytes of human blood were stored at 4℃ in darkness for 4 hours. Upon the storage erythrocytes were separated by the fractional centrifugal method. The effect of divalent metallic ions on the percent of dye uptake rate of Evans' blue as a neutral salt of a organic dye in the presence of 580mM glucose was observed and the following results were obtained. 1. The dye uptake rate was found to be kinetically proportional in function of incubation period in the stored eryrocytes for 4 hours with the dye uptake of 42.2 percent for 120 minutes incubation. 2. The statistical analysis of this effect of the relationship between the incubation period and the percent dye uptake rate was found to be very highly significant (p<0.001). 3. The effect of magnesium ion (5 mM) on the percent dye uptake rate in function of incubation times was kinetically increased in human matured erythrocytes when compared to that of control group. At the end of 40 minutes of incubation the human matured erythrocytes treated with magnesium ion ( 5 mM) increased about 1.5 times more of 30.5 percent dye uptake than the control group of 20.3 percent dye uptake. 4. The effect of magnesium ion was slightly accelerated with the addition of 0.01 mM magnesium ion; between 0.05 mM and 10 mM of magnesium ions the influence of this divalent metallic ion was greatest. 5. The increase in the concentration of copper ion inhibited proportionally and remarkablly the percent dye uptake rate by human matured erythrocytes. Fifty percent inhibitory concentration (1_50) of copper ion on the percent dye uptake rate by human matured erythrocytes was found to be 10.07 micromoles. 6. Also, the effect of ferrous ion (5 micromoles) on the percent dye uptake rate is human matured erythrocytes for 40 minutes incubation was found to be 21.4 percent inhibition and it inhibited that the effect of hematin (5 micormoles) on the percent dye uptake rate o Evans' blue by 65.6 percent points for 40 minutes incubation. 7. No effect was exerted on the percent dye uptake rate in human matured erythrocytes during the incubation periods by the addition of calciumion (5 mM) and manganese ion (tmicromoles). 8. The addition of lithium ion at the concentration of 5 micormoles to reactant mixture was effectively increased on the percent dye uptake rate of Evans' blue for a incubation of 40 minutes when compared to that control group (20.3%) to 43.9 percent. In view of the above findings it is clear that the effect of magnesium ion and lithium ion, as divalent metallic ions, on the Evans' blue absorbed into non-nucleated erythrocytes is considered to accelerate this enhancing effect while it does not accelerate that of hematin and copper ion. However, the effects of calcium ion and manganese ion was ineffective on the percent dye uptake of Evans' blue by human matured erythrocytes.

교육용 비디오 자료에서의 자막 특성을 이용한 대표화면추출 및 자막화면추출에 관한 연구

유신(Sheen Lew),신희정(HeeJung Sheen),이완주(WanJoo Lee),이병래(Yongkyu Kim),김용규(ByeongRae Lee),강현철(Hyunchul Kang) 한국정보과학회 1999 한국정보과학회 학술발표논문집 Vol.26 No.1B

본 연구에서는 자막특성을 이용하여 대표 프레임 추출과 문자 인식을 위한 문자 프레임 추출을 수행함과 동시에 장면전환을 검출할 수 있는 시스템을 구현하였다. 이는 기존의 방식인 장면전환 검출을 통해 비디오자료를 샷(shot)단위로 구조화하고 단순대표 프레임으로 각 샷의 내용을 요약하는 방식과는 달리, 비디오 스트림의 내용에 기반하여, 중요도가 상대적으로 높은 프레임을 대표 프레임으로 추출, 대표 프레임의 의미적(semantic)효용성을 보장한다. 이러한 기법은 교육용 비디오자료 특성에 기반하여 적용되었으며, 본 논문에서 제안한 시스템은 수행시간과 정확성면에서 뛰어난 특성을 보였다.

샷 분류에 의한 교육용 비디오 자료에서의 대표화면 추출

유신(Sheen Lew),조선길(Sungil Cho),신희정(HeeJung Sheen),양춘석(Yang Chunsuck),이완주(WanJoo Lee),이병래(ByeongRae Lee),김용규(Yongkyu Kim),강현철(Hyunchul Kang) 한국통신학회 1999 한국통신학회 학술대회논문집 Vol.1999 No.7

The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles

Yhun Yhang, Sheen,Minjung, Cho,Wan-Seob, Cho,Mina, Choi,Sueng Jun, Kim,Beam Seak, Han,Sheen Hee, Kim,Hyoung Oak, Kim,Ja Young, Jeong 이화여자대학교 약학연구소 2010 藥學硏究論文集 Vol.- No.20

Many approaches for the application of nano-sized particles to the human body as nanotechnology have been recently developed. The size of nanoparticles is related to their useful character and also plays a key role in toxicity. Since this surface area can interact with biological components of cells, nanoparticles can be more reactive in than larger particles. In the present study, a fluorescence dye-labeled 50, 100 and 200 nm-sized silica particle suspension was intravenously injected into mice to identify the toxicity, tissue distribution and excretion of silica nanoparticles in vivo. Incidence and severity of inflammatory response was transiently increased with injection of 200 and 100 nm silica nanoparticles within 12h. But there was no significant response related to injection of 50 nm particles. The silica particles of 50, 100 and 200 nm were cleared via urine and bile. The 50 nm silica anoparticles cleared to urine and bile than 100 nm and particles of 200 nm existed at lower concentration than other two smaller particles in urine and feces. Silica nanoparticles were trapped by macrophages in the spleen and liver and remained there until 4 weeks after the single injection.

미용서비스 종사자의 직무스트레스와 직무소진의 관계에서 자아탄력성의 매개효과

신영식(Young Seek Sheen),권도희(Do Hee Kwon),오경희(Kyung Hee Oh),신라미(La Mee Sheen) 한국인체미용예술학회 2017 한국인체미용예술학회지 Vol.18 No.4

This study aimed to figure out correlations among job stress, ego resilience and job burn out in beauty salon workers. For this, a questionnaire survey was administered to 300 beauty salon workers in Busan and the capital region from May 2nd to 31st, 2014. Except for 44 poorly answered ones, 256 copies were used for a final analysis. For analysis of the data, the analysis was conducted to analyze the frequency analysis and the validity of the measurement of the measurement participants’ characteristics. In addition, a correlation analysis was conducted to verify the validity of the variables and the identification validity of the variables, and conducted a regression analysis to verify the suitability and validity of the research model. The study results found the following: while a positive correlation was found between job stress and job burn out, a negative correlation was observed between ego resilience and job burn out. In other words, job stress has a negative effect on beauty salon workers’ life as well as their working environment. In contrast, ego resilience reduces job burn out by helping staff build the ability to handle problems in a positive manner.

Magnitude scaling relationships using P waves for earthquake early warning in South Korea

Sheen, D. H.,Lim, I. S.,Park, J. H.,Chi, H. C. The Association of Korean Geosciences Societies 2014 Geosciences Journal Vol.18 No.1

The scaling relationships of the peak displacement, P (d) , and the maximum predominant period, tau (p) (max) , of P waves were investigated to estimate magnitudes for earthquake early warning in South Korea. P (d) and tau (p) (max) were measured for 504 vertical records from 70 earthquakes at distances of 20 to 100 km. The earthquakes occurred between 2001 and 2011 and ranged from M (L) = 3.0 to 5.2. Since the events were generally low to moderate in magnitude, the parameter for a real-time high-pass filter was adjusted and the first 3 seconds of the P-waves were processed. The scaling relationships of P (d) and tau (p) (max) obtained from iterative regressions were M = 1.17 log(P (d) ) + 0.87 log(R) + 6.57 and M = 3.30 log(tau (p) (max) ) + 5.75, respectively, where R is the epicentral distance in kilometers, P (d) is in centimeters, and tau (p) (max) is in seconds. The average errors of the magnitude estimates obtained from the mean of the P (d) magnitude and tau (p) (max) were 0.06 magnitude units for the calibration data but 0.37 for a recent magnitude 3.9 event, which implies that the scaling relationships can be used in these forms but the relationships still need to be improved with more data to be useful for mitigating damage from future earthquakes around the Korean Peninsula.

Time domain Gauss–Newton seismic waveform inversion in elastic media

Sheen, Dong-Hoon,Tuncay, Kagan,Baag, Chang-Eob,Ortoleva, Peter J. Blackwell Publishing Ltd 2006 Geophysical journal international Vol.167 No.3

<P>SUMMARY</P><P>We present a seismic waveform inversion methodology based on the Gauss–Newton method from pre-stack seismic data. The inversion employs a staggered-grid finite difference solution of the 2-D elastic wave equation in the time domain, allowing accurate simulation of all possible waves in elastic media. The partial derivatives for the Gauss–Newton method are obtained from the differential equation of the wave equation in terms of model parameters. The resulting wave equation and virtual sources from the reciprocity principle allow us to apply the Gauss–Newton method to seismic waveform inversion. The partial derivative wavefields are explicitly computed by convolution of forward wavefields propagated from each source with reciprocal wavefields from each receiver. The Gauss–Newton method for seismic waveform inversion was proposed in the 1980s but has rarely been studied. Extensive computational and memory requirements have been principal difficulties which are addressed in this work. We used different sizes of grids for the inversion, temporal windowing, approximation of virtual sources, and parallelizing computations. With numerical experiments, we show that the Gauss–Newton method has significantly higher resolving power and convergence rate over the gradient method, and demonstrate potential applications to real seismic data.</P>

Paradigm Shift in Intra-Arterial Mechanical Thrombectomy for Acute Ischemic Stroke : A Review of Randomized Controlled Trials after 2015

Sheen, Jae Jon,Kim, Young Woo The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.4

Three randomized control trials (RCTs), published in 2013, investigated efficacy of mechanical thrombectomy in large vessel occlusions and did not show better results compared to intravenous (IV) recombinant tissue-type plasminogen activator (tPA) alone. However, most clinicians treating stroke consider mechanical thrombectomy as the standard treatment rather than using IV tPA alone. This paradigm shift was based on five RCTs investigating efficacy of mechanical thrombectomy in acute ischemic stroke conducted from 2010 to 2015. They demonstrated that mechanical thrombectomy was effective and safe in acute ischemic stroke with anterior circulation occlusion when performed within 6 hours of stroke onset. There are four reasons underlying the different results observed between the trials conducted in 2013 and 2015. First, the three RCTs of 2013 used low-efficiency thrombectomy devices. Second, the three RCTs used insufficient image selection criteria. Third, following the initial presentation at the hospital, reperfusion treatment required a long time. Fourth, the three RCTs showed a low rate of successful recanalization. Time is the most important factor in the treatment of acute ischemic stroke. However, current trends utilize advanced imaging techniques, such as diffusion-weighted imaging and multi-channel computer tomographic perfusion, to facilitate the detection of core infarction, penumbra, and collateral flows. These efforts demonstrate that patient selection may overcome the barriers of time in specific cases.

Low frequency cultural noise

Sheen, Dong-Hoon,Shin, Jin Soo,Kang, Tae-Seob,Baag, Chang-Eob American Geophysical Union 2009 Geophysical research letters Vol.36 No.17