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      • KCI우수등재

        Intrauterine diabetic milieu instigates dysregulated adipocytokines production in F1 offspring

        ( Shady H. Tawfik ),( Maha M. Haiba ),( Mohamed I. Saad ),( Taha M. Abdelkhalek ),( Mervat Y. Hanafi ),( Maher A. Kamel ) 한국동물자원과학회(구 한국축산학회) 2017 한국축산학회지 Vol.59 No.1

        Background: Intrauterine environment plays a pivotal role in the origin of fatal diseases such as the metabolic syndrome. Diabetes is associated with low-grade inflammatory state and dysregulated adipokines production. The aim of this study is to investigate the effect of maternal diabetes on adipocytokines (adiponectin, leptin and TNF-α) production in F1 offspring in rats. Methods: The offspring groups were as follows: F1 offspring of control mothers under control diet (CD) (CF1-CD), F1 offspring of control mothers under high caloric diet (HCD) (CF1-HCD), F1 offspring of diabetic mothers under CD (DF1-CD), and F1 offspring of diabetic mothers under HCD (DF1-HCD). Every 5 weeks post-natal, 10 pups of each subgroup were culled to obtain blood samples for biochemical analysis. Results: The results indicate that DF1-CD and DF1-HCD groups exhibited hyperinsulinemia, dyslipidemia, insulin resistance and impaired glucose homeostasis compared to CF1-CD (p > 0.05). DF1-CD and DF1-HCD groups had high hepatic and muscular depositions of TGs. The significant elevated NEFA level only appeared in offspring of diabetic mothers that was fed HCD. DF1-CD and DF1-HCD groups demonstrated low serum levels of adiponectin, high levels of leptin, and elevated levels of TNF-α compared to CF1-CD (p > 0.05). These results reveal the disturbed metabolic lipid profile of offspring of diabetic mothers and could guide further characterization of the mechanisms involved. Conclusion: Dysregulated adipocytokines production could be a possible mechanism for the transgenerational transmittance of diabetes, especially following a postnatal diabetogenic environment. Moreover, the exacerbating effects of postnatal HCD on NEFA in rats might be prone to adipcytokine dysregulation. Furthermore, dysregulation of serum adipokines is a prevalent consequence of maternal diabetes and could guide further investigations to predict the development of metabolic disturbances.

      • A Case Study for a Zero Impact Building in Belgium: Mondo Solar-2002

        Attia, Shady Sustainable Building Research Center 2011 International journal of sustainable building tech Vol.2 No.2

        This paper presents the Solar-2002 zero impact renovation project in Belgium. Its characteristics are based on fundamental principles taking advantage of natural resources by diverting the sun shine and rain in the building design. The building has been renovated aiming to achieve principals of occupant health and comfort, energy efficiency, renewable energy production, resource conservation and reduction of environmental impacts. The paper reviews the design concepts including the passive and active strategies and compare building actual performance to actual monitoring results. Innovations related to architectural design, building system performance and simulation are presented. Results show that the house achieved energy and carbon neutral balance, closed water cycle and almost a cradle to cradle building material cycle. However, monitoring results shows the difficulty to maintain optimal thermal comfort during extreme summer and winter periods. Achieving the environmental zero impact objectives is not economically feasible without the subsidies from the federal and regional government.

      • KCI등재

        Epoxylite Influence on Field Electron Emission Properties of Tungsten and Carbon Fiber Tips

        Alnawasreh, Shady S,Al-Qudah, Ala'a M,Madanat, Mazen A,Bani Ali, Emad S,Almasri, Ayman M,Mousa, Marwan S Korean Society of Microscopy 2016 Applied microscopy Vol.46 No.4

        This investigation deals with the process of field electron emission from composite microemitters. Tested emitters consisted of a tungsten or carbon-fiber core, coated with a dielectric material. Two coating materials were used: (1) Clark Electromedical Instruments Epoxylite resin and (2) Epidian 6 Epoxy resin (based on bisphenol A). Various properties of these emitters were measured, including the current-voltage characteristics, which are presented as Fowler-Nordheim plots, and the corresponding electron emission images. A field electron microscope with a tip (cathode) to screen (anode) distance of 10 mm was used to electrically characterize the emitters. Measurements were carried out under ultra-high vacuum conditions with a base pressure of $10^{-6}$ Pascal ($10^{-8}$ mbar).

      • KCI등재

        New process for ex situ electrokinetic pollutant removal. I: Process evaluation

        Ahmed Abou-Shady,Changsheng Peng 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.6

        Soil electrokinetic remediation (SEKR) is a proven technique for treating inorganic, organic, and radionuclide pollutants, particularly in fine-grained soils. The main obstacle to implementing SEKR is the high pH zone adjacent to the cathode surface, which adversely affects electromigration and electroosmosis mechanisms. There have been many attempts to overcome this drawback, but most of the intended solutions are impractical due to excessive cost or the need for chemical additives. We developed a new process for soil electrokinetic treatment in which the cathode is a vertical perforated pipe inserted into the soil. The removals of Pb2+ and Zn2+ from kaolinite were evaluated using the Taguchi approach, in which the effects of five four-level parameters (operation time, electrical potential, cathode gap, concentration, and hydrostatic head) were analyzed. The perforated cathode pipe SEKR system (PCPSS) was designed to investigate vertical soil electrokinetic remediation, which has not been extensively studied. The obtained results showed that increasing the cathode gap and hydrostatic head enhanced electroosmosis role. Satisfactory removal of Zn2+ (93.9%) was achieved, however the maximum removed Pb2+ was 42.7%. The removed Pb2+ and Zn2+ above the cathode gap was much better than the cathode. The effects of cathode gap, concentration, and hydrostatic head did not exhibit any influence on current passing.

      • KCI등재

        A Feasible Approximation to Optimum Decision Support System for Multidimensional Cases through a Modular Decomposition

        Ivan Vrana,Shady Aly 한국지능시스템학회 2009 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.9 No.4

        The today’s decision making tasks in globalized business and manufacturing become more complex, and ill-defined, and typically multiaspect or multi-discipline due to many influencing factors. The requirement of obtaining fast and reliable decision solutions further complicates the task. Intelligent decision support system (DSS) currently exhibit wide spread applications in business and manufacturing because of its ability to treat ill-structuredness and vagueness associated with complex decision making problems. For multi-dimensional decision problems, generally an optimum single DSS can be developed. However, with an increasing number of influencing dimensions, increasing number of their factors and relationships, complexity of such a system exponentially grows. As a result, software development and maintenance of an optimum DSS becomes cumbersome and is often practically unfeasible for real situations. This paper presents a technically feasible approximation of an optimum DSS through decreasing its complexity by a modular structure. It consists of multiple DSSs, each of which contains the homogenous knowledge’s, decision making tools and possibly expertise’s pertaining to a certain decision making dimension. Simple, efficient and practical integration mechanism is introduced for integrating the individual DSSs within the proposed overall DSS architecture.

      • KCI등재

        A Feasible Approximation to Optimum Decision Support System for Multidimensional Cases through a Modular Decomposition

        Vrana, Ivan,Aly, Shady Korean Institute of Intelligent Systems 2009 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.9 No.4

        The today's decision making tasks in globalized business and manufacturing become more complex, and ill-defined, and typically multiaspect or multi-discipline due to many influencing factors. The requirement of obtaining fast and reliable decision solutions further complicates the task. Intelligent decision support system (DSS) currently exhibit wide spread applications in business and manufacturing because of its ability to treat ill-structuredness and vagueness associated with complex decision making problems. For multi-dimensional decision problems, generally an optimum single DSS can be developed. However, with an increasing number of influencing dimensions, increasing number of their factors and relationships, complexity of such a system exponentially grows. As a result, software development and maintenance of an optimum DSS becomes cumbersome and is often practically unfeasible for real situations. This paper presents a technically feasible approximation of an optimum DSS through decreasing its complexity by a modular structure. It consists of multiple DSSs, each of which contains the homogenous knowledge's, decision making tools and possibly expertise's pertaining to a certain decision making dimension. Simple, efficient and practical integration mechanism is introduced for integrating the individual DSSs within the proposed overall DSS architecture.

      • The 'Architect-friendliness' Of Six Building Performance Simulation Tools: A Comparative Study

        Weytjens, Lieve,Attia, Shady,Verbeeck, Griet,De Herde, Andre Sustainable Building Research Center 2011 International journal of sustainable building tech Vol.2 No.3

        Concerning net zero energy buildings, providing early design support for architects has never been more important. In this context, building performance simulation tools could be a strong supportive technique, when integrated early in the architectural design process. However, despite the available range of tools, most of them do not meet the architects' requirements. To identify this gap, this study compared the 'architect-friendliness' of six state-of-the-art simulation tools, to highlight the architects' requirements for these tools and to develop guidelines for researchers and tool developers. The examined tools included ECOTECT, IES/VE - Sketch-Up, Energy10, eQuest, HEED, and Design Builder. The analysis was based on an extensive list of criteria defining the user-friendliness of tools from an architect's point of view. The results show that no single tool is entirely adequate to assist the architect's decision-making process. One of the major limitations is the poor communication and visualization of the output results.

      • KCI등재

        Hybrid fuzzy sliding mode for stick-slip suppression in drill string systems

        Abdelbasset Krama,Mohamed Gharib,Shady S. Refaat,Sadok Sassi 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.3

        Stick-slip vibration is one of the main factors that contribute greatly to reducing the service life of drill string equipment and decreasing the efficiency of the overall drilling system. Thus, it would be very desirable to overcome the challenge of stick-slip vibration via an effective control strategy. This paper proposes a new robust active controller based on the fuzzy sliding mode approach to suppress stick-slip vibration and to maintain the angular velocity of the drill components at the desired references. A discontinuous lumped parameter torsional model of a vertical drill string based on four degrees of freedom is used in this study. In addition to the drill bit and rotary table, the drill pipes and drill collars are included in the model. Moreover, nonlinear interactions between the drill bit and the rocks, including friction torque and the mud drilling effect, are considered. The proposed hybrid controller is based on a combination of artificial intelligence and a discontinuous first-order sliding mode control approach. A comprehensive numerical analysis was conducted by means of MATLAB and Simulink software. Real-time implementation of the system was conducted using dSPACE control board. The proposed controller has been tested under severe weight on bit variation and at different angular velocities. The results of the simulation and the real-time implementation are presented to demonstrate the good performance and feasibility of the proposed controller.

      • KCI등재

        The Effects of Dielectric Coatings on Electron Emission from Tungsten

        Al-Qudah, Ala'a M.,Alnawasreh, Shady S.,Madanat, Mazen A.,Trzaska, Oliwia,Matykiewicz, Danuta,Alrawshdeh, Saad S.,Hagmann, Mark J.,Mousa, Marwan S. Korean Society of Microscopy 2017 Applied microscopy Vol.47 No.1

        Field electron emission measurements were performed on dielectric-coated tungsten emitters, with apex radii in the nanometer and micrometer range, which were prepared by electrochemical etching in NaOH solution. Measurements were performed in a field electron microscopy (FEM) with a base pressure <$10^{-6}$ Pascal ($10^{-8}$ mbar). Four different types of dielectric were used, namely: (1) Clark Electromedical Instruments epoxylite resin, (2) Epidian 6 produced by Ciech Sarzyna S. A., (3) a Radionox solution of colloidal graphite; and (4) Molyslip 2001 E compound ($MoS_2$ and MoS). Current-voltage measurements and FEM images were used to investigate the characteristics of these composite emitters, and to assess how the different types of dielectric coating affect the suitability of the composite emitter as a potential electron source.

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